骨成長產品的全球市場 - Focused Insights(2024年～2029年)

2023年至2029年，全球骨生長產品市場規模預計將以3.72%的複合年增長率成長。

市場機會與推動因素

自供電植入式裝置的興起

侵入式骨骼生長刺激器是一種植入式設備，可將電能傳送到未癒合的骨折或骨融合部位，以誘導骨形成、刺激生長並促進癒合。這些設備使用透過植入導線傳遞的直流電向骨折部位傳遞一致的電流，克服了非侵入性系統中發現的患者依從性問題。侵入式刺激器特別適用於脛骨、股骨和肱骨的非骨融合，並用於接受腰椎或骶骨融合的高風險患者（有融合失敗史或有吸煙、肥胖或糖尿病等健康狀況的患者）已被證明對患者有效。骨頭是一種壓電材料，因此應變會產生微小的電荷，有助於癒合。此類設備的優勢越來越大，因此在已開發國家擴大採用，並且正在進行研究以提高其市場佔有率和有效性。

骨形態發生蛋白（BMP）對脊椎融合和骨再生的影響

骨形態發生蛋白 (BMP) 是轉化生長因子-β (TGF-β) 家族的一部分，已成為自體骨移植的有前途的替代品，特別是在脊椎融合手術和骨再生中。 BMP 於 2002 年獲得 FDA 批准用於前路腰椎融合術，旨在促進骨癒合，並且比傳統植入方法併發症更少。與髂嵴移植（ICBG）的76%相比，BMP顯示出98%的高效率，並且適用於椎間融合、後外側融合和環週融合等各種脊椎融合技術。 BMP 在安全性和有效性方面與 ICBG 相當，並且正在擴展到適應症外用途，例如後路脊椎融合和頸椎融合。 BMP 與 FGF、PDGF 和 IGF 等其他生物因子一起，在促進骨再生中發揮重要作用。儘管自體移植仍然是骨科手術的標準，但 BMP 提供了一個經過充分研究的有效替代方案。

擴大採用生物相容性合成骨移植物和生物製劑

越來越多地使用生物相容性合成骨移植物和生物製劑是骨生長產品市場的主要驅動力。由陶瓷、聚合物和複合材料等材料製成的合成骨移植物模仿天然骨結構，為新骨生長提供支架，同時消除與同種異體移植物和自體移植物相關的疾病，降低傳播和免疫排斥的風險。這些植入物尤其適合脊椎融合手術和創傷病例。骨形態發生蛋白 (BMP) 和富血小板血漿 (PRP) 等生物製劑可透過促進細胞活性和骨生長來促進自然骨癒合。 BMP 誘導骨形成並改善複合骨折的結果，而 PRP 則促進癒合。這些創新正在改變骨損傷的治療方法，提供更有效、高效和個人化的解決方案，並隨著醫療保健提供者尋求更安全、更具成本效益的選擇而擴大市場，我們正在促進成長。

產業限制因子

應對快速的技術進步

骨骼生長刺激劑價格昂貴，通常不在保險範圍內，促使許多人尋求經濟實惠的替代療法，如物理治療、阿育吠陀和脊椎按摩療法。由於成本效益高，這些替代藥物在日本、中國和印度等地區很受歡迎。此外，骨刺激器引起的不適以及骨科醫生的缺乏迫使患者轉向傳統治療。提高意識、改善治療機會和擴大保險範圍可能會支持中低收入地區採用骨生長產品。

競爭狀況

市場競爭非常激烈，美敦力 (Medtronic)、強生 (Johnson & Johnson)、史賽克 (Stryker) 和 Zimmer Biomet 等跨國公司透過收購、合作和新產品推出處於領先地位。越來越多的中小企業進入市場，創新、高性價比的產品備受關注。為了應對骨再生的課題，特別是老年人和糖尿病患者的骨再生課題，人們越來越重視開發先進的骨癒合療法，例如脈衝電磁場療法。 Bioventus、Orthofix 和 Terumo 等領先公司正在透過創新解決方案增強其產品組合。

主要供應商

• Bioventus
• Enovis Corp
• Johnson & Johnson
• Medtronic
• Orthofix
• Stryker Corp
• Zimmer Biomet

其他的著名供應商

• Altis Biologics
• Bio-Dynamic Technologies
• BTT Health
• Cellumed
• Elizur
• EmCyte
• Fintek Bio-Electric
• IGEA
• ITO
• Kinex Medical
• Ossatec Benelux
• Pain Rehab Products
• Royal Biologics
• Fujifilm Corp
• Smith & Nephew
• Specialized Orthopedic Solutions
• Stimulate Health
• Terumo
• Globus Medical
• ATEC
• Moximed
• Anika Therapeutics
• Highridge Medical

本報告提供全球骨成長產品市場相關調查分析，各地區的收益與預測，預測與機會，競爭情形等資訊。

目錄

第1章 骨成長產品市場概要

• 摘要整理
• 主要調查結果

第2章 骨成長產品市場

第3章 骨成長產品市場區隔資料

• 全球收益的預測:各產品
  • 骨生長刺激植入裝置
  • 骨形成蛋白
  • 多血小板血漿
• 全球收益的預測:各用途
  • 脊椎融合手術
  • 口腔·顎顏面手術
  • 癒合延遲·不癒合骨折
  • 其他
• 全球收益的預測:各終端用戶
  • 醫院·診療所
  • 專門整形外科·脊椎中心
  • 門診病人手術中心(ASC)

第4章 主要地區概要

• 北美的骨成長產品市場收益的預測
  • 美國的骨成長產品市場收益的預測
  • 加拿大的骨成長產品市場收益的預測
• 歐洲的骨成長產品市場收益的預測
  • 德國的骨成長產品市場收益的預測
  • 法國的骨成長產品市場收益的預測
  • 英國的骨成長產品市場收益的預測
  • 義大利的骨成長產品市場收益的預測
  • 西班牙的骨成長產品市場收益的預測
• 亞太地區的骨成長產品市場收益的預測
  • 中國的骨成長產品市場收益的預測
  • 日本的骨成長產品市場收益的預測
  • 印度的骨成長產品市場收益的預測
  • 澳洲的骨成長產品市場收益的預測
  • 韓國的骨成長產品市場收益的預測
• 南美的骨成長產品市場收益的預測
  • 巴西的骨成長產品市場收益的預測
  • 墨西哥的骨成長產品市場收益的預測
  • 阿根廷的骨成長產品市場收益的預測
• 中東·非洲的骨成長產品市場收益的預測
  • 土耳其的骨成長產品市場收益的預測
  • 沙烏地阿拉伯的骨成長產品市場收益的預測
  • 南非的骨成長產品市場收益的預測

第5章 骨成長產品市場預測和機會

• 骨成長產品市場機會和趨勢
• 骨成長產品市場促進因素
• 骨成長產品市場阻礙因素

第6章 骨成長產品產業概要

• 骨成長產品市場 - 競爭情形
• 骨成長產品市場 - 主要供應商的簡介
• 骨成長產品市場 - 其他的著名供應商
• 骨成長產品市場 - 主要策略的推薦事項

第7章 附錄

The global bone growth products market is expected to grow at a CAGR of 3.72% from 2023 to 2029.

MARKET OPPORTUNITIES & DRIVERS

The Rise of Self-Powered Implantable Devices

Invasive bone growth stimulators are implantable devices that supply electrical energy to non-healing fractures or bone fusion sites, aiming to induce bone formation, stimulate growth, and promote healing. These devices, which use direct current delivered via an implanted lead, offer a consistent current to the fracture site, overcoming issues related to patient compliance seen in non-invasive systems. Invasive stimulators are particularly indicated for non-unions of the tibia, femur, and humerus and have proven effective for high-risk individuals undergoing lumbar or sacral fusion, including those with a history of fusion failure or conditions such as smoking, obesity, or diabetes. Bone, being a piezoelectric material, generates a small electrical charge under strain, which aids in healing. The growing advantages of these devices suggest increased adoption in developed countries, with ongoing research to enhance their market presence and efficacy.

Impact of Bone Morphogenetic Proteins (BMPs) in Spinal Fusion and Bone Regeneration

Bone morphogenetic proteins (BMPs), part of the transforming growth factor-beta (TGF-beta) family, have become a promising alternative to autologous bone grafts, especially in spinal fusion and bone regeneration. Approved by the FDA in 2002 for anterior lumbar fusion, BMPs aim to enhance bone healing with fewer complications than traditional grafting methods. They have shown high effectiveness, with fusion rates of 98% compared to 76% for iliac crest grafts (ICBGs), and are used in various spinal fusion techniques, including interbody, posterolateral, and circumferential fusion. BMPs are comparable to ICBGs in safety and efficacy and are expanding into off-label uses, such as posterior spinal fusion and cervical fusion. BMPs, alongside other biological factors like FGF, PDGF, and IGF, play a significant role in advancing bone regeneration. While autologous grafts remain the standard in orthopedic procedures, BMPs offer a well-researched, effective alternative.

The Rising Adoption of Biocompatible Synthetic Bone Grafts and Biologics

The growing use of biocompatible synthetic bone grafts and biologics is a key driver of the bone growth products market. Synthetic grafts, made from materials like ceramics, polymers, and composites, mimic natural bone structure, providing scaffolds for new bone growth while reducing disease transmission and immune rejection risks associated with allografts and autografts. These grafts are especially in demand for spinal fusion surgeries and trauma cases. Biologics, such as bone morphogenetic proteins (BMPs) and platelet-rich plasma (PRP), enhance natural bone healing by promoting cellular activity and bone growth. BMPs induce bone formation, improving outcomes in complex fractures, while PRP accelerates healing. These innovations are transforming the treatment of bone injuries, offering more effective, efficient, and personalized solutions, driving market growth as healthcare providers seek safer, cost-effective options.

INDUSTRY RESTRAINTS

Keeping Up with Rapid Technical Advancements

Bone growth stimulators are expensive and often not covered by insurance, leading many to seek affordable alternatives like physiotherapy, Ayurveda, and chiropractic care, especially in developing countries with high out-of-pocket costs. Due to their cost-effectiveness, these alternatives are popular in regions like Japan, China, and India. Additionally, discomfort from bone stimulators and a shortage of orthopedic surgeons drive patients toward traditional treatments. Expanding awareness, improving treatment access, and increasing insurance coverage could boost the adoption of bone growth products in low- and middle-income areas.

SEGMENTATION INSIGHTS

INSIGHTS BY PRODUCT

The global bone growth products market by product is segmented into bone growth stimulator devices, bone morphogenetic protein, and platelet-rich plasma. The bone growth stimulator devices segment accounted for the largest market share. Bone healing is a natural process, with the body continually replacing old bone with new. While fractures generally heal with appropriate treatments like casts, realignment, and surgery, complications such as delayed healing or non-union can occur. To address these issues, medical professionals seek ways to enhance and accelerate bone healing. Bone stimulators are designed to support this healing process and come in various forms, including electrical and ultrasonic stimulators. This segment dominates the market due to many patients preferring non-invasive or minimally invasive treatments to avoid surgical risks and long recovery periods. Bone growth stimulators, which can be used externally or with minimal intervention, align with this growing patient preference.

By Product

• Bone Growth Stimulator Devices
• Bone Morphogenetic Protein
• Platelet Rich Plasma

INSIGHTS BY APPLICATION

The global bone growth products market by application is categorized into spinal fusion surgeries, oral & maxillofacial surgeries, delayed union & non-union bone fractures, and others. The spinal fusion surgeries show the highest growth during the forecast period. Bone Growth Stimulation (BGS) is a therapeutic technique commonly prescribed by surgeons following spinal fusion procedures to enhance the healing of bones in the spine. A bone growth stimulator is often used for patients undergoing cervical (neck) or lumbar (low back) spine surgeries to promote spinal fusion. This device helps to improve bone healing by stimulating growth and is particularly beneficial in cases where the fusion process is delayed or fails. Studies have shown that BGS significantly enhances fusion outcomes in both cervical and lumbar regions, making it a popular choice for post-operative treatment, thus helping segmental growth.

By Application

• Spinal Fusion Surgeries
• Oral & Maxillofacial Surgeries
• Delayed Union & Non-union Bone Fractures
• Others

INSIGHTS BY END-USER

Based on the end-user, the hospitals & clinics segment holds the largest global bone growth products market share. Hospitals serve as the primary point of care for bone-related issues, often investing in advanced technologies and materials to improve treatment outcomes. However, only larger multispecialty and Tier-I hospitals provide cutting-edge treatments such as bone morphogenetic proteins (BMP) and platelet-rich plasma (PRP). This is due to the complexity and cost of these therapies. Increasing patient awareness and improved insurance coverage have fueled the demand for advanced treatments, including bone stimulators, BMP, and PRP, which are particularly effective for treating difficult fractures like non-union fractures. Physician offices and clinics, especially in remote areas, are many patients' first point of contact. While these facilities may not be able to offer advanced treatments, they play a crucial role in referring patients to larger, specialized hospitals, which are helping the market grow.

By End-User

• Hospitals & Clinics
• Specialty Orthopedic & Spine Centers
• Ambulatory Surgical Centers (ASCs)

GEOGRAPHICAL ANALYSIS

North America accounted for the largest global bone growth products market share, followed by Europe. The U.S. remains a major revenue contributor in North America due to the high penetration of spinal fusion procedures and a considerable volume of spinal fusion and non-fusion surgeries. The increasing prevalence of orthopedic diseases, accidental injuries, and the aging population primarily drive the growth. The availability of advanced, safer, and minimally invasive surgical treatments and ongoing technological innovations further support market expansion.

In Europe, Germany, France, the UK, Italy, and Spain are the primary revenue contributors to the global bone growth products market. This region benefits from a well-established and sophisticated healthcare infrastructure, providing access to advanced medical services, including spinal fusion and non-fusion procedures. The market's growth is driven by the increasing prevalence of bone disorders and the availability of reimbursement coverage for spinal fusion surgeries across many European countries.

By Geography

• North America
  • The U.S.
  • Canada
• Europe
  • Germany
  • France
  • UK
  • Italy
  • Spain
• APAC
  • China
  • Japan
  • India
  • Australia
  • South Korea
• Latin America
  • Brazil
  • Mexico
  • Argentina
• Middle East & Africa
  • Turkey
  • Saudi Arabia
  • South Africa

COMPETITIVE LANDSCAPE

The global bone growth products market report includes exclusive data on 30 vendors. The market is highly competitive, with global players like Medtronic, Johnson & Johnson, Stryker, and Zimmer Biomet leading through acquisitions, collaborations, and new product launches. Small and mid-sized companies increasingly enter the market, focusing on novel, cost-effective products. There is a growing emphasis on developing advanced bone healing therapies, such as pulsed electromagnetic field therapies, to address challenges in bone regeneration, especially for elderly and diabetic patients. Key players like Bioventus, Orthofix, and Terumo are enhancing their product portfolios with innovative solutions.

Key vendors

• Bioventus
• Enovis Corp
• Johnson & Johnson
• Medtronic
• Orthofix
• Stryker Corp
• Zimmer Biomet

Other Prominent Vendors

• Altis Biologics
• Bio-Dynamic Technologies
• BTT Health
• Cellumed
• Elizur
• EmCyte
• Fintek Bio-Electric
• IGEA
• ITO
• Kinex Medical
• Ossatec Benelux
• Pain Rehab Products
• Royal Biologics
• Fujifilm Corp
• Smith & Nephew
• Specialized Orthopedic Solutions
• Stimulate Health
• Terumo
• Globus Medical
• ATEC
• Moximed
• Anika Therapeutics
• Highridge Medical

KEY QUESTIONS ANSWERED:

1. How big is the global bone growth products market?

2. What Is the growth rate of the global bone growth products market?

3. Which region dominates the global bone growth products market?

4. Who are the major players in the global bone growth products market?

5. What are the key drivers of the global bone growth products market?

TABLE OF CONTENTS

CHAPTER - 1: Bone Growth Products Market Overview

• Executive Summary
• Key Findings

CHAPTER - 2: Bone Growth Products Market

• GLOBAL: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)

CHAPTER - 3: Bone Growth Products Market Segmentation Data

• GLOBAL: Projected Revenue by Product (2020-2029; $Millions)
  • Bone Growth Stimulator Devices
  • Bone Morphogenetic Protein
  • Platelet Rich Plasma
• GLOBAL: Projected Revenue by Application (2020-2029; $Millions)
  • Spinal Fusion Surgeries
  • Oral & Maxillofacial Surgeries
  • Delayed Union & Non-union Bone Fractures
  • Others
• GLOBAL: Projected Revenue by End-User (2020-2029; $Millions)
  • Hospitals & Clinics
  • Specialty Orthopedic & Spine Centers
  • Ambulatory Surgical Centers (ASCs)

CHAPTER - 4: Key Regions Overview

• North America: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in US
  • Projected Revenue of Bone Growth Products Market in Canada
• Europe: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in Germany
  • Projected Revenue of Bone Growth Products Market in France
  • Projected Revenue of Bone Growth Products Market in UK
  • Projected Revenue of Bone Growth Products Market in Italy
  • Projected Revenue of Bone Growth Products Market in Spain
• APAC: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in China
  • Projected Revenue of Bone Growth Products Market in Japan
  • Projected Revenue of Bone Growth Products Market in India
  • Projected Revenue of Bone Growth Products Market in Australia
  • Projected Revenue of Bone Growth Products Market in South Korea
• Latin America: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in Brazil
  • Projected Revenue of Bone Growth Products Market in Mexico
  • Projected Revenue of Bone Growth Products Market in Argentina
• Middle East & Africa: Projected Revenue of Bone Growth Products Market (2020-2029; $Millions)
  • Projected Revenue of Bone Growth Products Market in Turkey
  • Projected Revenue of Bone Growth Products Market in Saudi Arabia
  • Projected Revenue of Bone Growth Products Market in South Africa

CHAPTER - 5: Bone Growth Products Market Prospects & Opportunities

• Bone Growth Products Market Opportunities & Trends
• Bone Growth Products Market Drivers
• Bone Growth Products Market Constraints

CHAPTER - 6: Bone Growth Products Industry Overview

• Bone Growth Products Market - Competitive Landscape
• Bone Growth Products Market - Key Vendor Profiles
• Bone Growth Products Market - Other Prominent Vendors
• Bone Growth Products Market - Key Strategic Recommendations

CHAPTER - 7: Appendix

• Research Methodology
• Abbreviations
• About Arizton

LIST OF EXHIBITS

Exhibit 1: Projected Revenues of Global Bone Growth Products (2020-2029, $ MN)

Exhibit 2: Market Size & Forecast - Bone Growth Stimulator Devices (2020-2029, $ MN)

Exhibit 3: Market Size & Forecast - Bone Morphogenetic Protein (2020-2029, $ MN)

Exhibit 4: Market Size & Forecast - Platelet Rich Plasma (2020-2029, $ MN)

Exhibit 5: Market Size & Forecast - Spinal Fusion Surgeries (2020-2029, $ MN)

Exhibit 6: Market Size & Forecast - Oral & Maxillofacial Surgeries (2020-2029, $ MN)

Exhibit 7: Market Size & Forecast - Delayed Union & Non-union Bone Fractures (2020-2029, $ MN)

Exhibit 8: Market Size & Forecast - Others (2020-2029, $ MN)

Exhibit 9: Market Size & Forecast - Hospitals & Clinics (2020-2029, $ MN)

Exhibit 10: Market Size & Forecast - Specialty Orthopedic & Spine Centers (2020-2029, $ MN)

Exhibit 11: Market Size & Forecast - Ambulatory Surgical Centers (ASCs) (2020-2029, $ MN)

Exhibit 12: Projected Revenues of Bone Growth Products in North America (2020-2029, $ MN)

Exhibit 13: Projected Revenues of Bone Growth Products in the US (2020-2029, $ MN)

Exhibit 14: Projected Revenues of Bone Growth Products in Canada (2020-2029, $ MN)

Exhibit 15: Projected Revenues of Bone Growth Products in Europe (2020-2029, $ MN)

Exhibit 16: Projected Revenues of Bone Growth Products in Germany (2020-2029, $ MN)

Exhibit 17: Projected Revenues of Bone Growth Products in France (2020-2029, $ MN)

Exhibit 18: Projected Revenues of Bone Growth Products in the UK (2020-2029, $ MN)

Exhibit 19: Projected Revenues of Bone Growth Products in Italy (2020-2029, $ MN)

Exhibit 20: Projected Revenues of Bone Growth Products in Spain (2020-2029, $ MN)

Exhibit 21: Projected Revenues of Bone Growth Products in APAC (2020-2029, $ MN)

Exhibit 22: Projected Revenues of Bone Growth Products in China (2020-2029, $ MN)

Exhibit 23: Projected Revenues of Bone Growth Products in Japan (2020-2029, $ MN)

Exhibit 24: Projected Revenues of Bone Growth Products in India (2020-2029, $ MN)

Exhibit 25: Projected Revenues of Bone Growth Products in Australia (2020-2029, $ MN)

Exhibit 26: Projected Revenues of Bone Growth Products in South Korea (2020-2029, $ MN)

Exhibit 27: Projected Revenues of Bone Growth Products in Latin America (2020-2029, $ MN)

Exhibit 28: Projected Revenues of Bone Growth Products in Brazil (2020-2029, $ MN)

Exhibit 29: Projected Revenues of Bone Growth Products in Mexico (2020-2029, $ MN)

Exhibit 30: Projected Revenues of Bone Growth Products in Argentina (2020-2029, $ MN)

Exhibit 31: Projected Revenues of Bone Growth Products in the MEA (2020-2029, $ MN)

Exhibit 32: Projected Revenues of Bone Growth Products in Turkey (2020-2029, $ MN)

Exhibit 33: Projected Revenues of Bone Growth Products in Saudi Arabia (2020-2029, $ MN)

Exhibit 34: Projected Revenues of Bone Growth Products in South Africa (2020-2029, $ MN)

LIST OF TABLES

LIST OF TABLES

Table 1: Projected Revenues of Global Bone Growth Products Market (2020-2029, $ MN)

Table 2: Global Bone Growth Products Market by Product (2020-2029, %)

Table 3: Global Bone Growth Products Market by Product (2020-2029, $ MN)

Table 4: Global Bone Growth Products Market by Application (2020-2029, %)

Table 5: Global Bone Growth Products Market by Application (2020-2029, $ MN)

Table 6: Global Bone Growth Products Market by End-User (2020-2029, %)

Table 7: Global Bone Growth Products Market by End-User (2020-2029, $ MN)

Table 8: Global Bone Growth Products Market by Geography (2020-2029, %)

Table 9: Global Bone Growth Products Market by Geography (2020-2029, $ MN)