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市場調查報告書

商品編碼

1672884

無細胞蛋白質表現市場按產品類型、應用、最終用戶和地區分類

Cell-free Protein Expression Market, By Product Type, By Application, By End User, By Geography

出版日期: 2025年02月07日 | 出版商:

Coherent Market Insights | 英文 182 Pages | 商品交期: 2-3個工作天內

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簡介目錄

2025 年全球無細胞蛋白質表現市場規模估計為 3.414 億美元，預計到 2032 年將達到 5.594 億美元，2025 年至 2032 年的複合年成長率為 7.3%。

報告範圍		報告詳細資訊
基準年	2024	2025 年市場規模	3.414億美元
效能資料	2020-2024	預測期	2025-2032
預測期：2025 年至 2032 年複合年成長率	7.30%	2032 年金額預測	5.594億美元

數字。 2025 年無細胞蛋白質表現市場佔有率（%）（按地區分類）

無細胞蛋白質表現（也稱為體外蛋白質合成）是一種生物技術過程，利用來自細菌、酵母菌和其他細胞的細胞成分（例如核醣體、胺基酸、DNA/mRNA 和其他因子）在試管中在活細胞外產生活性蛋白質。無細胞系統不是使用細菌或酵母等生物體來生產蛋白質，而是描述了一種靈活的套件，可以在活細胞外、易於控制的環境中透過轉錄和翻譯等機制來編程表達。這使得可以使用無細胞方法來生產對宿主細胞有毒或難以在細胞中表現的蛋白質。由於生物製藥、合成生物學和基礎生物學研究等行業對快速、可擴展且經濟高效的蛋白質生產技術的需求不斷增加，無細胞蛋白質表現市場正在不斷成長。

市場動態

推動無細胞蛋白質表現市場成長的關鍵因素是生物醫學研究和治療開發對功能性天然人類蛋白質的需求不斷增加。與傳統的原核和真核表達方法相比，無細胞系統正在得到更快的採用，因為它們可以快速、可擴展且經濟地評估多種蛋白質變體，而無需對活細胞進行基因操作。然而，製備細胞裂解物和最佳化反應條件的技術挑戰阻礙了該技術的廣泛商業化。針對各種蛋白質類別最佳化的穩健、標準化無細胞平台的開發將有助於克服現有的缺點並擴大應用。持續交換無細胞 (CECF) 方法和結合無細胞表達和下游分析的整合系統的日益普及為市場提供了有利可圖的機會。

研究的主要特點

本報告對全球無細胞蛋白表達市場進行了詳細分析，並提供了預測期（2025-2032）的市場規模和年複合成長率（CAGR%），假設 2024 年為基準年。

它還揭示了各個領域的潛在商機，並解釋了該市場的有吸引力的投資提案矩陣。

它還提供了對市場促進因素、限制因素、機會、新產品發布和核准、市場趨勢、區域前景以及主要企業採用的競爭策略的重要見解。

全球無細胞蛋白表達市場的主要企業根據公司亮點、產品系列、關鍵亮點、財務績效和策略等參數進行分析。

主要企業包括賽默飛世爾科技公司 (Thermo Fisher Scientific, Inc.)、Takara Bio Inc.、默克公司 (Merck KGaA)、New England Biolabs、Bio-Rad Laboratories, Inc.、Promega Corporation、Jena Bioscience GmbH、GeneCopoeia, Inc.、CellFree Sciences Co.Ltd.、Cube BIoTech GmbH、Moderna Therapeutics、BIoTechrabbit GmbH 和 Profacgen。

本報告的見解將使負責人和企業經營團隊能夠就未來產品發布、新興趨勢、市場擴張和行銷策略做出明智的決策。

全球無細胞蛋白質表現市場報告迎合了該行業的各個相關人員，例如投資者、供應商、產品製造商、經銷商、新進業者和金融分析師。

相關人員將透過全球無細胞蛋白質表現市場分析中使用的各種策略矩陣來做出決策。

Report Coverage	Report Details
Base Year:	2024	Market Size in 2025:	USD 341.4 Mn
Historical Data for:	2020 To 2024	Forecast Period:	2025 To 2032
Forecast Period 2025 to 2032 CAGR:	7.30%	2032 Value Projection:	USD 559.4 Mn

Cell-free protein expression, also known as in vitro protein synthesis, is a biotechnological process that utilizes cellular components like ribosomes, amino acids, DNA/mRNA, and other factors from bacteria, yeast, or other cells to produce active proteins outside living cells in a test tube. Rather than using live organisms like bacteria or yeast to produce proteins, cell-free systems provide a flexible toolkit to program expression through mechanisms like transcription and translation outside living cells in an easily controlled environment. This allows proteins which are toxic to the host cell or difficult to express intracellularly to be produced using cell-free methods. The cell-free protein expression market is growing due to the increasing demand for rapid, scalable, and cost-effective techniques for protein production across industries like biopharmaceuticals, synthetic biology, and basic biological research.

Market Dynamics:

The major drivers fueling growth in the cell-free protein expression market include rising demand for functional and native human proteins in biomedical research and therapeutics development. Cell-free systems allow rapid, scalable, and economical evaluation of multiple protein variants without genetic manipulation of live cells which is accelerating its adoption over traditional prokaryotic and eukaryotic expression methods. However, technical challenges related to optimizing cell lysate preparation and reaction conditions restrain the wider commercialization of this technique. Development of robust, standardized cell-free platforms optimized for different protein classes can help address existing shortcomings and expand applications. Growing deployment of continuous-exchange cell-free (CECF) methods and integrated systems coupling cell-free expression with downstream analysis presents lucrative opportunities in the market.

Key Features of the Study:

This report provides in-depth analysis of the global cell-free protein expression market, and provides market size (US$ Mn) and compound annual growth rate (CAGR%) for the forecast period (2025-2032), considering 2024 as the base year

It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market

This study also provides key insights about market drivers, restraints, opportunities, new product launches or approvals, market trends, regional outlook, and competitive strategies adopted by key players

It profiles key players in the global cell-free protein expression market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies

Key companies covered as a part of this study include Thermo Fisher Scientific, Inc., Takara Bio Inc., Merck KGaA, New England Biolabs, Bio-Rad Laboratories, Inc., Promega Corporation, Jena Bioscience GmbH, GeneCopoeia, Inc., CellFree Sciences Co., Ltd., Cube Biotech GmbH, Moderna Therapeutics, Biotechrabbit GmbH, and Profacgen

Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics

The global cell-free protein expression market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts

Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global cell-free protein expression market

Market Segmentation

By Product Type Insights (Revenue, USD Mn, 2019 - 2032)
- Expression Systems
- Insect Cells Cell-free Protein Expression System
- coli Cell-free Protein Expression System
- Rabbit Reticulocytes Cell-free Protein Expression System
- Others
- Reagents
- Others (Vectors, yeast cell extracts, etc.)
By Application Insights (Revenue, USD Mn, 2019 - 2032)
- Enzyme Engineering
- High Throughput Production
- Protein-Protein interaction
- Others (High Throughput Production, etc.)
By End User Insights (Revenue, USD Mn, 2019 - 2032)
- Biotechnological Companies
- Pharmaceutical Companies
- Contract Research Organizations
- Others (Academic and Research Institutes, etc.)
Regional Insights (Revenue, USD Mn, 2019 - 2032)
- North America
- U.S.
- Canada
- Latin America
- Brazil
- Argentina
- Mexico
- Rest of Latin America
- Europe
- Germany
- U.K.
- Spain
- France
- Italy
- Russia
- Rest of Europe
- Asia Pacific
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
- Middle East
- GCC Countries
- Israel
- Rest of Middle East
- Africa
- South Africa
- North Africa
- Central Africa
Key Players Insights
- Thermo Fisher Scientific, Inc.
- Takara Bio Inc.
- Merck KGaA
- New England Biolabs
- Bio-Rad Laboratories, Inc.
- Promega Corporation
- Jena Bioscience GmbH
- GeneCopoeia, Inc.
- CellFree Sciences Co., Ltd.
- Cube Biotech GmbH
- Moderna Therapeutics
- Biotechrabbit GmbH
- Profacgen

1. Research Objectives and Assumptions

Research Objectives
Assumptions
Abbreviations

2. Market Purview

Report Description
- Market Definition and Scope
Executive Summary
- Cell-free Protein Expression Market, By Product Type
- Cell-free Protein Expression Market, By Application
- Cell-free Protein Expression Market, By End User
- Cell-free Protein Expression Market, By Region

3. Market Dynamics, Regulations, and Trends Analysis

Market Dynamics
Impact Analysis
Key Highlights
Regulatory Scenario
Product Launches/Approvals
PEST Analysis
PORTER's Analysis
Merger and Acquisition Scenario
Market Trends
Key Developments

4. Global Cell-free Protein Expression Market, By Product Type, 2020-2032, (USD Mn)

Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021 - 2032
- Segment Trends
Expression Systems
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
- Insect Cells Cell-free Protein Expression System
- coli Cell-free Protein Expression System
- Rabbit Reticulocytes Cell-free Protein Expression System
- Others
Reagents
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
Others (Vectors, yeast cell extracts, etc.)
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)

5. Global Cell-free Protein Expression Market, By Application, 2020-2032, (USD Mn)

Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021 - 2032
- Segment Trends
Enzyme Engineering
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
High Throughput Production
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
Protein-Protein interaction
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
Others (High Throughput Production, etc.)
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)

6. Global Cell-free Protein Expression Market, By End User, 2020-2032, (USD Mn)

Introduction
- Market Share Analysis, 2025 and 2032 (%)
- Y-o-Y Growth Analysis, 2021 - 2032
- Segment Trends
Biotechnological Companies
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
Pharmaceutical Companies
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
Contract Research Organizations
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)
Others (Academic and Research Institutes, etc.)
- Introduction
- Market Size and Forecast, and Y-o-Y Growth, 2020-2032, (USD Mn)

7. Global Cell-free Protein Expression Market, By Region, 2020 - 2032, Value (USD Mn)

Introduction
- Market Share (%) Analysis, 2025,2028 & 2032, Value (USD Mn)
- Market Y-o-Y Growth Analysis (%), 2021 - 2032, Value (USD Mn)
- Regional Trends
North America
- Introduction
- Market Size and Forecast, By Product Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- U.S.
- Canada
Latin America
- Introduction
- Market Size and Forecast, By Product Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- Brazil
- Argentina
- Mexico
- Rest of Latin America
Europe
- Introduction
- Market Size and Forecast, By Product Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- Germany
- U.K.
- Spain
- France
- Italy
- Russia
- Rest of Europe
Asia Pacific
- Introduction
- Market Size and Forecast, By Product Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- China
- India
- Japan
- Australia
- South Korea
- ASEAN
- Rest of Asia Pacific
Middle East
- Introduction
- Market Size and Forecast, By Product Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country, 2020 - 2032, Value (USD Mn)
- GCC Countries
- Israel
- Rest of Middle East
Africa
- Introduction
- Market Size and Forecast, By Product Type, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Application, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By End User, 2020 - 2032, Value (USD Mn)
- Market Size and Forecast, By Country/Region, 2020 - 2032, Value (USD Mn)
- South Africa
- North Africa
- Central Africa

8. Competitive Landscape

Thermo Fisher Scientific, Inc.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Takara Bio Inc.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Merck KGaA
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
New England Biolabs
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Bio-Rad Laboratories, Inc.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Promega Corporation
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Jena Bioscience GmbH
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
GeneCopoeia, Inc.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
CellFree Sciences Co., Ltd.
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Cube Biotech GmbH
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Moderna Therapeutics
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Biotechrabbit GmbH
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies
Profacgen
- Company Highlights
- Product Portfolio
- Key Developments
- Financial Performance
- Strategies