市場調查報告書
商品編碼
1272769
2023-2030 年細胞培養蛋白表面塗層的全球市場Global Cell Culture Protein Surface Coating Market - 2023-2030 |
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細胞培養蛋白表面塗層的全球市場規模預計到 2022 年將達到 8.434 億美元,到 2030 年將達到 18.105 億美元,在預測期內(2023-2030 年)增長 10.3%。預計將增長複合年增長率。 主要參與者增加產品發布將有助於在預測期內促進細胞培養蛋白表面塗層市場的增長。 例如,2020年6月,康寧公司推出了包括Matrigel matrix-3D板在內的新產品。
作為附加表面處理的塗層是指為增強細胞粘附而進行的任何附加修改,以及製造商對所有細胞培養塑料進行的標準等離子或電暈處理。 塗層通常用蛋白質或□完成。 細胞培養的一個缺點是它需要高度熟練的人員,動物細胞比許多常見的污染物(細菌、病毒和真菌)生長得慢,並且必須在嚴格的無菌技術下進行。
3D 細胞培養的額外維度是影響細胞反應的關鍵特徵。 這不僅會影響與周圍細胞相互作用的細胞表面受體的空間組織,還會對細胞施加物理限制。
3D 培養的這些空間和物理方面從外到內影響細胞信號,最終影響基因表達和細胞行為。 與 2D 培養相比,3D 培養中的細胞反應已被證明可以更接近地模擬體內行為。
細胞培養需要持續監測以防止污染,同時要避免細胞培養蛋白表面塗層的浪費,它本身也很昂貴,影響了市場增長。
此外,組織組成是可變的和異質的。 來自同一樣本的副本具有不同的成分。 必須通過連續傳代多次操作細胞系才能重現實驗結果。
例如,任何文化都會與原本不同,其構成也不統一。 為了解決這個問題,複製品在每一代隨機混合,生長條件的選擇壓力傾向於產生最佳顯性表型。 這些缺點將阻礙細胞培養蛋白表面塗層市場的增長。
根據 2022 年 7 月發表在《臨床病毒學雜誌》上的一份報告,在培養物中分離出 SARS-CoV-2 的概率、出現症狀的天數更少以及 RT-PCR 循環閾值更低之間存在顯著差異。存在顯著的正相關。
因此,在 COVID-19 中,細胞培養被用於正確診斷,這有望推動細胞培養蛋白表面塗層市場的增長。 病毒研究仍在進行中,因此預計將在未來產生重大影響。
俄羅斯和烏克蘭之間的衝突中斷了文化中使用的某些設備的供應鏈,增加了消費者的成本,並使他們更難獲得所需的設備。 這些因素對細胞培養蛋白表面塗層市場產生了重大影響。
The global cell culture protein surface coating market size was valued at US$ 843.4 million in 2022 and is estimated to reach US$ 1,810.5 million by 2030, growing at a CAGR of 10.3% during the forecast period (2023-2030). An increase in the product launches by major key players helps to boost cell culture protein surface coating market growth over the forecast period. For instance, in June 2020, Corning Incorporated launched new products, including Matrigel matrix-3D plates.
Coating as an additional surface treatment stands for all additional modifications made to increase cell adhesion and the standard plasma or corona treatment performed on all cell culture plastic by the manufacturer. Usually, a coating is done with proteins or peptides. The disadvantages of cell culture are: highly skilled personnel, techniques must be performed using strict asepsis techniques because animal cells grow slower than many of the common contaminants (bacteria, viruses, and fungi).
The additional dimensionality of 3D cell cultures is the crucial feature leading to the differences in cellular responses. It not only influences the spatial organization of the cell surface receptors engaged in interactions with surrounding cells, but it also induces physical constraints on cells.
These spatial and physical aspects in 3D cultures affect the signal transduction from the outside to the inside of cells and ultimately influence gene expression and cellular behavior. It has been demonstrated that cell responses in 3D cultures are more similar to in vivo behavior compared to 2D cultures.
Cell cultures should be constantly monitored to prevent contamination and avoid wastage of protein surface coating of the cell cultures, which can be expensive in nature, thereby impacting the growth of the market.
In addition, tissue composition is variable and heterogeneous. Replicas from the same sample have various constituents. To replicate an experimental result, cell lines must be manipulated many times in serial passages.
For instance, every culture will be different from the original and less uniform in its constitution. The replicas are randomly mixed in each passage to resolve this issue, and the selective pressure of growing conditions tends to produce an optimal prevalent phenotype. These disadvantages will hamper the cell culture protein surface coating market growth.
As per the report published by the Journal of Clinical Virology in July 2022, there was a significant positive correlation between the probability of isolating SARS-CoV-2 in culture, fewer days of symptoms, and a lower RT-PCR cycle threshold value.
Hence, the cell culture was used during COVID-19 for proper diagnosis and was expected to drive the growth of the cell culture protein surface coatings market. As viral studies are still ongoing, it is expected to have a significant impact in the coming future.
The conflict between Russia and Ukraine has caused a disruption of the supply chain for some of the equipment used in culture, increasing costs for consumers and making it more difficult for them to access the necessary equipment. These factors have had a significant impact on the cell culture protein surface coating market.
The global cell culture protein surface coating market is segmented based on coating type, protein source, and region.
In coating type segment, the precoating segment accounted for the highest cell culture protein surface coating market size of around 3/5th in 2022. Depending on the quality and quantity control of the plasma treatment surface of the flask, petri dish or microwell plates are activated for adhesion either homogeneously or artefacts, and it may be inserted, as regions like edges are not treated or parts in the middle area or over or under activated.
Another important part of choosing a cell culture consumable supplier is the construction design. Multiwell plates and petri dishes are strongly influenced by adhesion.
One of the secrets that allow Canada to punch above its weight in the biomanufacturing economy is the tradition of collaboration between academia, industry, non-profits, and government support. In British Columbia, both the University of Victoria and the University of British Columbia have strong undergraduate programs in biomedical engineering that provide an important supply of talent to feed the growing biomanufacturing ecosystems and address challenges in regenerative medicine.
The Canadian government has already invested 1.2 billion dollars into a national biomanufacturing strategy that they continue to support. The Canadian government also supports research and development through its national funding agency - the Natural Sciences and Engineering Research Council.
The major global players include Thermo Fisher Scientific, Corning, Merck, PerkinElmer, Greiner Bio-One International GmbH, Agilent Technologies, BRAND GMBH + CO KG, Kollodis BioSciences, DenovoMATRIX, and faCellitate among others.
The global cell culture protein surface coating market report would provide approximately 92 tables, 108 figures and 195 Pages.
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