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市場調查報告書
商品編碼
1634171
全球乾粉吸入器 (DPI) 市場 - 2025 - 2033Global Dry Powder Inhalers (DPIs) Market - 2025 - 2033 |
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2024年,全球乾粉吸入器市場規模達到10.2億美元,預計2033年將達到15.6億美元,2025-2033年預測期間複合年成長率為5.1%。
乾粉吸入器 (DPI) 是將粉狀藥物直接注入肺部的醫療設備。它們通常用於治療氣喘和慢性阻塞性肺病(COPD)等呼吸系統疾病。乾粉吸入器的特徵是其呼吸活化機制,確保只有當患者透過吸嘴深用力吸氣時藥物才會釋放。與利用推進劑給藥的計量吸入器 (MDI) 不同,DPI 利用患者的吸入將粉末狀藥物分散成氣霧劑形式,從而到達肺部狹窄的氣道。
對乾粉吸入器的需求不斷成長是預測期內推動市場的促進因素。例如,呼吸系統疾病的日益流行增加了對乾粉吸入器的需求,因為它們在慢性呼吸系統疾病的治療和管理中發揮著至關重要的作用。例如,根據美國氣喘和過敏基金會的數據,美國有近 2800 萬人患有氣喘。這相當於大約每十二個人中就有一個。在美國,氣喘影響著 18 歲及以上的近 2,300 萬人。女性比男性更容易患氣喘。氣喘影響約 11.0% 的成年女性和 6.8% 的男性。它是青少年的主要慢性疾病。目前,約有 490 萬名 18 歲以下兒童患有氣喘。
驅動程式和限制
對乾粉吸入器的需求不斷增加
對乾粉吸入器的需求不斷成長預計將成為全球乾粉吸入器市場成長的重要因素。呼吸系統疾病病例數量的增加、藥物輸送比傳統吸入器更方便、技術進步、研究經費增加以及認知的提高增加了對乾粉吸入器的需求並推動了市場。
隨著慢性阻塞性肺病、氣喘和鼻竇炎等慢性呼吸道疾病在全球範圍內變得越來越普遍,乾粉吸入器的需求不斷增加,因為它在支氣管炎、慢性阻塞性肺病和哮喘等慢性呼吸道疾病的管理和控制中發揮著重要作用。例如,根據衛生與公共服務部的數據,全球每 20 人就有 1 人患有慢性呼吸道疾病 (CRD)。東亞和南亞的 CRD 死亡率最高。中低和低社會人口指數 (SDI) 國家的 CRD 死亡率年齡標準化率最高。關於慢性呼吸道疾病 (CRD) 的新研究結果顯示,它是全球第三大死因,導致全球約 400 萬人死亡。這些人中約 60%(約 2.62 億)被診斷出患有氣喘,使其成為最常見的 CRD。自 1990 年以來,CRD 新病例數量增加了 49.0%,這主要是由於人口成長。另一方面,年齡標準化發生率下降了 5.3%。
與傳統吸入器相比,乾粉吸入器的藥物輸送簡單性和使用者友善性增加了需求。與典型吸入裝置相比,DPI 的主要優點之一是能夠將藥物直接輸送到肺部,而無需推進劑或液體。這項屬性不僅提高了患者的依從性,也減少了對環境的影響。 DPI 旨在方便用戶使用且便於攜帶,使其成為需要持續治療慢性呼吸系統疾病的患者的合適選擇。 DPI 的簡便性和有效性預計將提高其在醫療保健專業人員和患者中的接受度。
此外,DPI 設計和配方的技術進步正在推動市場擴張。諸如基於膠囊的設備等創新技術可減少水分暴露,從而提高可靠性和性能,從而提高患者滿意度和依從性。將智慧技術融入吸入器(例如監控使用情況的感測器),為改善治療結果和患者參與創造了新的前景。這些進步不僅滿足了現有患者的需求,也吸引了以前可能不願意採用吸入療法的新用戶。
用於開發和改進乾粉吸入器 (DPI) 的資金對於加強呼吸護理和增加有效治療的機會至關重要。例如,2023 年 10 月,美國食品藥物管理局 (FDA) 資助澳洲研究人員 100 萬澳元(687,000 美元),用於開發改進的乾粉吸入器測試程序。該計劃將使吸入器,特別是通用吸入器設備的開發更加有效,目標是為全球氣喘患者提供負擔得起的吸入器。
與使用乾粉吸入器相關的副作用
與使用乾粉吸入器相關的副作用等因素預計將阻礙全球乾粉吸入器市場。一個主要問題是鵝口瘡的流行,這是一種真菌疾病,當粉狀藥物沉積在口腔或喉嚨時就會發生。根據研究,透過 DPI 使用吸入性皮質類固醇會增加鵝口瘡的發生率,尤其是較大劑量時。患者可能會出現口腔不適、喉嚨刺激和聲音沙啞等症狀,這可能會影響他們繼續使用這些設備的意願。此外,有些人可能對乳糖敏感,乳糖是許多 DPI 中常見的載體,可能會導致乳糖不耐受患者胃腸道不適或過敏反應。
除了局部副作用外,透過 DPI 持續給予皮質類固醇可能會產生全身性副作用。隨著時間的推移,高劑量可能會導致骨質疏鬆症、糖尿病和其他全身性疾病等問題。這些潛在的健康危害可能會增加患者對長期使用 DPI 的焦慮,並導致不遵守規定的治療。
The global dry powder inhalers market reached US$ 1.02 billion in 2024 and is expected to reach US$ 1.56 billion by 2033, growing at a CAGR of 5.1% during the forecast period 2025-2033.
Dry powder inhalers (DPIs) are medical devices that administer powdered drugs directly into the lungs. They are generally used to treat respiratory disorders like asthma and chronic obstructive pulmonary disease (COPD). A dry powder inhaler is distinguished by its breath-activated mechanism, which ensures that the drug is only released when the patient inhales deeply and forcefully via the mouthpiece. Unlike metered-dose inhalers (MDIs), which utilize propellants to administer medication, DPIs employ the patient's inhalation to disperse the powdered medication into an aerosol form that can reach the narrow airways of the lungs.
The increasing demand for dry powder inhalers is the driving factor that drives the market over the forecast period. For instance, the increasing prevalence of respiratory diseases increases the demand for dry powder inhalers since they play a vital role in the treatment and management of chronic respiratory diseases. For instance, according to the Asthma and Allergy Foundation of America, Nearly 28 million people in the United States suffer from asthma. This equates to around one in every twelve people. Asthma affects almost 23 million persons in the United States, aged 18 and older. Asthma is more frequent in women than men. Asthma affects around 11.0% of female adults and 6.8% of male people. It is a major chronic disease among youngsters. Currently, around 4.9 million children under the age of 18 have asthma.
Market Dynamics: Drivers & Restraints
Increasing demand for dry powder inhalers
The increasing demand for dry powder inhalers is expected to be a significant factor in the growth of the global dry powder inhalers market. The increasing number of cases of respiratory disorders, ease of drug delivery than traditional inhalers, technological advancements, increased research funds, and increasing awareness increase the demand for dry powder inhalers and drive the market.
As chronic respiratory conditions like COPD, asthma, and sinusitis become more prevalent globally, the demand for dry powder inhalers increases as it plays an important role in the management and control of chronic respiratory diseases like bronchitis, COPD, and asthma. For instance, according to the Department of Health & Human Services, 1 in 20 people globally suffers from chronic respiratory disease (CRD). East Asia and South Asia had the highest rates of CRD mortality. Low-middle and low Socio-demographic Index (SDI) countries had the highest age-standardized rates of CRD deaths. New findings on chronic respiratory disease (CRD) now show it is the third leading cause of death globally, accounting for approximately 4 million deaths worldwide. Asthma was diagnosed in approximately 60% of these people (approximately 262 million), making it the most common CRD. Since 1990, the number of new cases of CRDs has increased by 49.0%, owing primarily to population growth. The age-standardized incidence rate, on the other hand, has decreased by 5.3%.
The ease of drug delivery and user-friendly nature of dry powder inhalers to traditional inhalers increase the demand. One of the primary advantages of DPIs over typical inhalation devices is their ability to deliver medication directly to the lungs, eliminating the need for propellants or liquids. This attribute not only improves patient compliance but also reduces environmental effects. DPIs are intended to be user-friendly and portable, making them a suitable option for patients who require ongoing treatment for chronic respiratory disorders. The ease and effectiveness of DPIs are projected to drive their acceptance among both healthcare professionals and patients.
Furthermore, technological advancements in DPI design and formulation are driving market expansion. Innovations like capsule-based devices that decrease moisture exposure improve dependability and performance, resulting in higher patient satisfaction and adherence. The incorporation of smart technology into inhalers, such as sensors that monitor usage, creates new prospects for improving treatment outcomes and patient participation. These advancements not only meet existing patient needs but also attract new users who may have previously been unwilling to adopt inhalation therapy.
The funding allocated for the development and improvement of dry powder inhalers (DPIs) is critical to enhancing respiratory care and increasing access to effective therapies. For instance, in October 2023, The US Food and Drug Administration (FDA) funded Australian researchers $AU1 million ($US687,000) to develop improved dry powder inhaler testing procedures. The initiative will enable more effective development of inhalers, particularly generic inhaler devices, with the goal of providing access to affordable inhalers for asthma patients across the globe.
Side effects associated with the usage of dry powder inhalers
Factors such as side effects associated with the usage of dry powder inhalers are expected to hamper the global dry powder inhalers market. One major issue is the prevalence of oral thrush, a fungal disease that can develop when powdered drugs settle in the mouth or throat. According to research, using inhaled corticosteroids via DPIs increases the incidence of oral thrush, especially at larger doses. Patients may endure symptoms such as discomfort in the mouth, throat irritation, and hoarseness, which can influence their willingness to continue using these devices. Furthermore, some people may be sensitive to lactose, a frequent carrier found in many DPIs, which can cause gastrointestinal discomfort or allergic responses in lactose-intolerant patients.
In addition to local side effects, there are concerns regarding systemic side effects from continuous corticosteroid administration via DPIs. High doses over time might result in problems such as osteoporosis, diabetes, and other systemic disorders. These potential health hazards can increase patient anxiety over long-term DPI use and lead to nonadherence to prescribed therapy.
The global dry powder inhalers market is segmented based on product type, dosage, indication type, distribution channel, and region.
The multi-dose dry powder inhalers segment is anticipated to dominate the global dry powder inhalers market owing to its cost-effectiveness, longer shelf life, ease of use, strategic partnerships, and increasing prevalence of respiratory disorders.
One of the primary benefits of MDPIs is their cost-effectiveness. These devices often have a longer shelf life and less pharmaceutical waste, making them cost-effective for both patients and healthcare systems. The combination of price and ease of use makes MDPIs a popular alternative, particularly as healthcare providers prioritize effective and efficient respiratory disease treatment solutions.
Technological developments will also play an important part in the expansion of the multi-dose segment. Smart inhalers, which combine digital health solutions, improve patient involvement and treatment adherence. These devices can monitor usage patterns, remind patients to take their prescriptions and provide feedback on inhaling practices, ultimately enhancing treatment outcomes. As healthcare systems increasingly adopt digital health technology, MDPIs are likely to gain from greater integration into patient care initiatives.
For instance, according to the American Lung Association, COPD affects 11.7 million adults, resulting in hundreds of thousands of emergency department visits and tens of billions of dollars in healthcare expenses each year. Moreover, according to the Cystic Fibrosis Foundation, Cystic fibrosis affects about 40,000 children and adults in the United States (an estimated 105,000 people have been diagnosed with the disease in 94 countries), and it can affect people of any ethnic background. So, multi-dose dry powder inhalers play an important role in the treatment and management of chronic respiratory disorders. The increasing number of chronic respiratory disorders upsurges the demand for multi-dose dry powder inhalers.
The strategic partnerships took place to enhance the quality and efficiency of the multi-dose dry powder inhalers. For instance, in May 2023, H&T Presspart, a global supplier of drug delivery devices and components, announced a collaborative partnership with Hovione, a specialist integrated CDMO and leader in spray drying and particle engineering, to develop the new Sunrise high-performance dry powder inhaler technology platform. H&T Presspart's revolutionary Sunriser technology is adaptable enough to meet the challenges of both traditional carrier-based and spray-dried tailored formulations, as well as an expanding range of dry powder formulations, new particle engineering, and powder processing technologies. As part of the collaborative development agreement, H&T Presspart will continue to develop and manufacture the Sunriser device.
The dominance of the North American market in the global dry powder inhaler market is due to various factors such as advanced healthcare infrastructure, high prevalence of respiratory diseases, strategic partnerships, technological advancements, product launches, and approvals, and increasing adoption of innovative medical technologies.
One of the primary factors contributing to North America's dominance in the dry powder inhaler market is technological improvements that improve the functionality and user experience of dry powder inhalers. Recent advances have focused on enhancing device usability, drug delivery accuracy, and patient adherence. Many recent DPI advancements include integrated dose counters and audible feedback mechanisms that assist patients in receiving the exact dosage while also serving as medication adherence reminders. Furthermore, advances in materials and design have resulted in the creation of lightweight, portable inhalers that are easier for patients to transport and use on the go.
For instance, in February 2024, Catalent, Inc., a global leader in enabling the development and supply of better therapies for patients, completed remodeling and device advancement to its capsule filling of Dry Powders for Inhalation and capsule blistering suites in Boston, MA, to handle strong pharmaceuticals. Catalent is currently the CDMO with the most GMP capacity for capsule spray-dried and carrier-based inhaled powders, due to recent enhancements that include more capacity for both development and commercial spray drying.
The increasing prevalence of respiratory disorders in this region increases the demand for dry powder inhalers. For instance, according to health.gov, respiratory diseases affect millions of people in the United States. More than 25 million people in the United States have asthma. Strategies to reduce environmental triggers and make sure people get the right medications can help prevent hospital visits for asthma. In addition, more than 16 million people in the United States have COPD (chronic obstructive pulmonary disease), which is a major cause of death.
Asia Pacific is growing at the fastest pace in the global dry powder inhalers market
The Asia Pacific region is emerging as the fastest-growing market for dry powder inhalers, owing to a combination of demographic trends, increased healthcare investment, recent launches, and an increasing prevalence of respiratory diseases.
The increasing prevalence of respiratory diseases is one of the factors that drive the market in this region. For instance, according to The International Primary Care Respiratory Group, India has one of the highest rates of chronic respiratory illness. India accounts for 15.69% of worldwide chronic respiratory diseases, whereas 30.28% of all global deaths from chronic respiratory diseases occur in India. India has the world's greatest number of COPD (Chronic Obstructive Pulmonary Disease) cases, totaling 55.23 million. India has the second-highest number of COPD-related deaths globally, accounting for almost 0.85 million.
There are recent product launches of anesthesia devices in this region. For instance, in 2023, Aptar Pharma launched Orbital Dry Powder Inhaler (DPI), a revolutionary device for delivering high-payload powder medication formulations directly to the lungs. This innovative inhaler technology stands out for its ability to give accurate and consistent dosing over several inhalations, which improves patient compliance and minimizes the risk of coughing during administration. The Orbital DPI is adaptable to both single-use and reuse applications, making it suitable for a wide range of therapeutic purposes.
The major global players in the global dry powder inhalers market include AstraZeneca, Boehringer Ingelheim International GmbH, Vectura Group Ltd, Otsuka Pharmaceutical Co., Ltd., Respira Therapeutics Inc., CHIESI Farmaceutici S.p.A., Cipla, GlaxoSmithKline plc., Hovione, Mankind Pharma among others.
Emerging Players
Merxin Ltd, Aerovate Therapeutics, and PULMATRiX, Inc. among others
The global dry powder inhalers market report delivers a detailed analysis with 60+ key tables, more than 50 visually impactful figures, and 176 pages of expert insights, providing a complete view of the market landscape.
Target Audience 2024
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