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市場調查報告書
商品編碼
1712541
全球胃癌治療市場 - 2025-2033Global Gastric Cancer Treatment Market - 2025-2033 |
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2024年全球胃癌治療市場規模達58.2億美元,預計2033年將達到146.6億美元,2025-2033年預測期內的複合年成長率為10.9%。
胃癌,也稱為胃癌,是指始於胃內壁細胞的一種癌症。它是世界上最常見和最致命的癌症之一,在東亞、歐洲和南美洲部分地區尤其常見。胃癌可以在胃的任何部位發展,並可能擴散到其他器官,如食道、胰臟、肝臟和淋巴結。
胃癌主要起源於胃壁上皮細胞,導致腺癌,這是最常見的胃癌類型(約佔 90-95% 的病例)。然而,胃癌也包括其他較為罕見的形式,如淋巴瘤(淋巴組織癌)、胃腸道間質瘤(GIST)和神經內分泌腫瘤。
駕駛員和約束裝置
標靶治療的不斷進步顯著推動了胃癌治療市場的成長
胃癌治療中最顯著的進步之一是 HER2 標靶療法的開發。 HER2(人類表皮生長因子受體 2)是一種在某些胃癌細胞中過度表現的蛋白質,導致細胞生長不受控制。曲妥珠單抗(赫賽汀)是一種針對 HER2 的單株抗體,是 HER2 陽性胃癌的突破性治療方法。這種治療方法的成功使得它與化療聯合治療晚期胃癌被廣泛使用。
例如,2024年10月,安斯泰來製藥公司宣布,美國食品藥品監督管理局(FDA)批准VYLOY(zolbetuximab-clzb)聯合含氟嘧啶和鉑類化療,用於一線治療局部晚期不可切除或轉移性人表皮生長因子受體2(HER2)陰性胃腺癌或胃食管連接部(CLGEFDA)檢測VYLOY 是美國首個也是唯一一個核准的 CLDN18.2 標靶療法
標靶治療的不斷進步成為胃癌治療市場成長的重要動力。朝向更個人化和有效的治療轉變,加上 FDA 對新藥的批准、不斷成長的市場接受度以及患者存活率的提高,都促進了這一成長。隨著該領域研究的不斷深入,預計標靶治療將更加精細化,為胃癌患者帶來更大的希望,市場規模也將進一步擴大。
與治療相關的副作用和安全問題阻礙了市場的成長
儘管胃癌治療取得了重大進展,但副作用和安全問題仍然是疾病管理的重大挑戰。傳統療法和標靶療法的不良反應常常使患者不願遵守規定的治療方案,影響他們的生活品質,並使治療方案複雜化。這些擔憂反過來又阻礙了胃癌治療市場的廣泛應用和成長。
化療仍然是胃癌治療的基石,但它會帶來一系列嚴重的副作用。這些可能導致劑量減少、治療停止和生活品質下降,最終阻礙市場成長。雖然標靶治療和免疫療法徹底改變了胃癌治療,但這些療法並非沒有風險。儘管它們的副作用往往比化療少,但它們仍然可能導致嚴重的免疫相關不良事件(irAE)或脫靶效應。
流行病學分析
胃癌的發生率呈上升趨勢。根據DataM情報估計,2024年全球患病人數預計將接近102萬,其中亞太地區患病人數最多,達1.9028億。透過篩檢進行早期發現、更好的治療選擇以及改善的公共衛生措施促使已開發國家的發病率和死亡率下降。然而,胃癌仍然是一個沉重的醫療負擔,特別是在發展中國家和高風險族群。
The global gastric cancer treatment market size reached US$ 5.82 billion in 2024 and is expected to reach US$ 14.66 billion by 2033, growing at a CAGR of 10.9% during the forecast period 2025-2033.
Gastric cancer, also known as stomach cancer, refers to a type of cancer that begins in the cells lining the stomach. It is one of the most common and deadly forms of cancer worldwide, particularly prevalent in East Asia, Europe, and parts of South America. Gastric cancer can develop in any part of the stomach and may spread to other organs, such as the esophagus, pancreas, liver, and lymph nodes.
Gastric cancer primarily originates from the epithelial cells that line the stomach, leading to adenocarcinoma, which is the most common type of gastric cancer (around 90-95% of cases). However, gastric cancer can also include other, rarer forms such as lymphoma (cancer of lymphatic tissue), gastrointestinal stromal tumors (GISTs), and neuroendocrine tumors.
Market Dynamics: Drivers & Restraints
Rising advancements in targeted therapies are significantly driving the gastric cancer treatment market growth
One of the most notable advancements in gastric cancer treatment has been the development of HER2-targeted therapies. HER2 (human epidermal growth factor receptor 2) is a protein overexpressed in some gastric cancer cells, leading to uncontrolled cell growth. Trastuzumab (Herceptin), a monoclonal antibody targeting HER2, has been a groundbreaking treatment for HER2-positive gastric cancer. The success of this treatment has led to its widespread use in combination with chemotherapy for advanced gastric cancer.
For instance, in October 2024, Astellas Pharma Inc. announced that the U.S. Food and Drug Administration (FDA) approved VYLOY (zolbetuximab-clzb) in combination with fluoropyrimidine- and platinum-containing chemotherapy for the first-line treatment of adults with locally advanced unresectable or metastatic human epidermal growth factor receptor 2 (HER2)-negative gastric or gastroesophageal junction (GEJ) adenocarcinoma whose tumors are claudin (CLDN) 18.2 positive as determined by an FDA-approved test. VYLOY is the first and only CLDN18.2-targeted therapy approved in the U.S.
The rising advancements in targeted therapies have been a significant driver for the growth of the gastric cancer treatment market. The shift towards more personalized and effective treatments, combined with the FDA approvals of new drugs, the growing market acceptance, and the increased survival rates in patients, all contribute to this growth. As the research in this field continues to progress, it is expected that targeted therapies will become even more refined, offering greater hope for gastric cancer patients and expanding the market further.
Side effects and safety concerns associated with the treatment are hampering the market growth
Despite the significant advancements in gastric cancer treatment, side effects and safety concerns continue to pose major challenges in the management of the disease. The adverse effects associated with both traditional and targeted therapies often deter patients from adhering to prescribed regimens, impact their quality of life, and complicate treatment regimens. These concerns, in turn, hinder the widespread adoption and growth of the gastric cancer treatment market.
Chemotherapy remains a cornerstone of treatment for gastric cancer, but it is associated with a range of severe side effects. These can lead to dose reductions, discontinuation of therapy, and decreased quality of life, which ultimately hampers market growth. While targeted therapies and immunotherapies have revolutionized gastric cancer treatment, these therapies are not without their risks. Although they tend to have fewer side effects than chemotherapy, they can still cause severe immune-related adverse events (irAEs) or off-target effects.
Epidemiology Analysis
The incidence of gastric cancer is rising. As per DataM intelligence estimates, nearly 1.02 million prevalent cases are estimated worldwide in 2024. The region with the highest prevalence is the Asia-Pacific, accounting for 190.28 million cases. Early detection through screening, better treatment options, and improved public health measures have contributed to the decline in incidence and mortality rates in developed countries. However, gastric cancer continues to present a major healthcare burden, particularly in developing nations and among high-risk populations.
The global gastric cancer treatment market is segmented based on cancer type, treatment type, route of administration, and region.
The chemotherapy segment is expected to dominate the gastric cancer treatment market with the highest market share
Chemotherapy is frequently used as the primary treatment in advanced gastric cancer, often in combination with targeted therapies or immunotherapy. In cases where surgery is not possible, chemotherapy serves as a crucial palliative treatment to control symptoms, slow the disease's progression, and improve survival rates. For instance, FOLFOX (a combination of 5-fluorouracil (5-FU), oxaliplatin, and leucovorin) is a standard chemotherapy regimen used in gastric cancer. This regimen is particularly effective for advanced gastric cancer and has been widely adopted.
Chemotherapy is frequently combined with targeted therapies like trastuzumab, ramucirumab, and nivolumab to enhance efficacy, especially in advanced or metastatic gastric cancer. These combination regimens have become the standard of care in many treatment protocols. The growing trend of combining chemotherapy with newer therapies has expanded its market dominance, as it remains the central component of first-line and second-line treatment regimens in both HER2-positive and HER2-negative gastric cancers.
North America is expected to hold a significant position in the global gastric cancer treatment market with the highest market share
The FDA (U.S. Food and Drug Administration) and Health Canada are at the forefront of regulatory approvals for new cancer therapies, including those for gastric cancer. These agencies have fast-tracked and drug approvals for novel treatments like TEVIMBRA (tislelizumab-jsgr), nivolumab (Opdivo), trastuzumab (Herceptin), and ramucirumab (Cyramza). This further accelerates the market growth in the region with various effective treatments.
For instance, in December 2024, BeiGene, Ltd., a global oncology company that intends to change its name to BeOne Medicines Ltd., announced the U.S. Food and Drug Administration (FDA) approved TEVIMBRA (tislelizumab-jsgr), in combination with platinum and fluoropyrimidine-based chemotherapy, for the first-line treatment of unresectable or metastatic HER2-negative gastric or gastroesophageal junction adenocarcinoma (G/GEJ) in adults whose tumors express PD-L1 (>=1).
North America has been a leader in adopting targeted therapies and immunotherapies, which are increasingly used to treat gastric cancer. The region's healthcare system supports the use of expensive, but highly effective, biologics and immunotherapy drugs that target specific proteins or immune checkpoints involved in cancer progression. For instance, Trastuzumab (Herceptin) is widely used for HER2-positive gastric cancer, and its combination with chemotherapy has led to better survival rates. Nivolumab (Opdivo), an immune checkpoint inhibitor, is also approved for use in gastric cancer and has been shown to significantly improve survival in combination with chemotherapy.
Top companies in the gastric cancer treatment market include Merck & Co., Inc., Eli Lilly and Company, Genentech USA, Inc., Pfizer Inc., Astellas Pharma Inc., Bristol-Myers Squibb Company, Blueprint Medicines Corporation, Daiichi Sankyo, Inc., BeiGene, Ltd., Ipsen Biopharmaceuticals Inc., Taiho Oncology, Inc., and Deciphera Pharmaceuticals, LLC., and among others.
The global gastric cancer treatment market report delivers a detailed analysis with 68 key tables, more than 61 visually impactful figures and 198 pages of expert insights, providing a complete view of the market landscape.
Target Audience 2024
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