細胞治療的自動化市場:技術，治療方法，策略，預測

本報告提供全球細胞治療的自動化市場相關調查，市場概要，以及各市場區隔的技術趨勢，市場影響要素，及加入此市場的主要企業簡介等資訊。

目錄

摘要整理

電池單元自動化技術

• 市場區隔
• 競爭技術
• 生物反應器
• 微電信業者
• 人口統計與成長
• 推動市場要素
• 危險因素

細胞培養監測

• 探針為基礎的感測器
  • 電化學感測器
  • 光化學感測器系統
• 膠囊技術
• 拋棄式感測器貼片
• 品管
  • CMC
  • 光譜感測器
• 技術課題
• 電子干涉

實行技術

• 自主感應技術
• 無線資料傳送
• 檢體濃度
• 技術的限制

自動細胞療法製造平台

• 下一代平台

市場要素

• 法規
  • FDA
  • GMP

企業簡介

“ Cell Therapy Automation: Technologies, Therapeutics, Strategies & Forecasts ” is a comprehensive evaluation and analysis of the technology, products and participants providing the driving force behind this growing oncolytic segment of the immunological therapy sector. The report has been designed and developed to provide pharmaceutical company decision makers, drug developers and formulators, device designers, and industry strategists with a detailed understanding of the expanding impact of cell therapy on pharmaceutical strategies and healthcare treatment protocols. Provider organization business managers, healthcare administrators and investors will also benefit from this publication.

Converging Factors Driving Cell Therapy Developments

Cell therapy has emerged as a promising new approach to treat malignancies that could only be treated on a palliative basis. Among those therapies, chimeric antigen receptor (CAR) modified T cell therapies has proved to be effective for hematological malignancies. To generate CAR T cells, patient- (autologous) or donor-derived (allogeneic) T cells are modified to express a CAR. The CAR is a chimeric construct containing at least one signaling domain of the T cell receptor and a single chain variable fragment (scFv).

The production of autologous CAR T cells is carried out by a variety of manufacturing approaches all comprising the same common steps. First, the patient's white blood cells (WBCs) are isolated by leukapheresis and washed. Then, the T cells are activated, transduced with the CAR transgene, expanded to the required cell numbers for therapy, formulated and filled. After quality control testing and preparatory lymphodepleting chemotherapy for the patient, the product is injected into the patient.

What You Will Learn:

• What current treatments are supplied as cell therapy treatments, how are they administered, what are the specifics, and who markets them?

• What cell Therapy treatments are in development, who are the developers, and what indications are they targeting?

• What are the major factors driving cell therapy demand?

• What is the size of the market today, who are the market share leaders, and what will the market share be in 2028?

• How important are drug developer relationships and what are the key alliances in the industry?

• What are the essential tech factors, technologies and market development issues for cell therapy products?

• What are the significant economic, technology, and regulatory factors affecting the market for cell therapy treatments?

Table of Contents

Executive Summary

Cell Automation Technologies

• Market Segments
• Competing Technologies
• Bioreactors
• Microcarriers
• Demographics and Growth
• Market Drivers
• Risk Factors

Cell Culture Monitoring

• Probe Based Sensors
  • Electrochemical Sensor
  • Optical Chemosensor Systems

• Capsule Technology
• Disposable Sensor Patches

• Quality Control
  • CMC
  • Spectroscopic Sensors

• Technical Challenges
• Electronic Interference

Enabling Technology

• Autonomous Sensor Technology
• Wireless Data Transmission

• Analyte Concentration
  • Photoluminescence Intensity
  • Absorption

• Technical Limitations
  • Electronic Interference

Automated Cell Therapy Manufacturing Platforms

• Next Generation Platforms
  • Cell Therapy Process Convergence
  • CT Process Standardization
  • Robotics

Market Factors

• Regulations
  • FDA
  • GMP

Company Profiles