吸入止痛藥：不斷發展的藥物和新的商機

隨著發達國家預期壽命的增加和人口老齡化，慢性和急性疼痛的發生率以及相關的發病率也在增加，這使得疼痛管理成為對患者及其家人而言更加重要的生活質量問題。這一點已經開始顯現。

本報告考察了吸入止痛藥市場，並概述了疼痛管理、監管環境、需求驅動因素分析、競爭格局和參與者概況。

內容

• 通過吸入治療疼痛
• 執行摘要
• 疼痛管理市場機會
• 疼痛管理指南的演變
• 疼痛管理實踐中的區域因素
• 疼痛管理的需求驅動因素
• 競爭格局
• 增長限制因素
• 吸入技術、平台、設計因素
• 制定
• 配方技術
• 輔料和釋放曲線
• 口服吸入器的設計因素
• 乾粉吸入器
• 固定劑量吸入器
• 霧化器
• 鼻內吸入
• 鼻內給藥的藥代動力學
• 鼻內器械的特點
• 績效因素
• 生物利用度
• 劑量重現性
• 活性化合物的穩定性
• 吸入器的主要短期止痛市場
• 突破性癌痛 (cBTP)
• 偏頭痛和叢集性頭痛
• 中度至重度疼痛
• 吸入性鎮痛產品
• FDA 批准的藥物
• 阿斯利康
• 葛蘭素史克
• 威朗特
• Mylan/Roxane/Apotex
• 酮咯酸
• 處於開發階段的藥物
• 布托啡諾
• 芬太尼
• 雙氫麥角胺
• 氯胺酮
• 嗎啡
• 全氯拉秦
• 曲坦類
• 市場因素
• 易於使用和患者偏好
• 監管問題
• 患者依從性
• CMO/CSO 的角色
• 公司簡介

‘Inhaled Pain Management: Evolving Therapeutics, Emerging Opportunities’ is a comprehensive evaluation and analysis of the technology, products and participants providing the driving force behind this evolving segment of the healthcare sector.

The study is designed to provide drug company decision makers, drug delivery developers, device designers, healthcare marketers, and supply chain participants with a detailed understanding of the economics, technologies, disease segments, and commercial opportunities for inhaled pain management drug therapeutics. Provider organization business managers, healthcare administrators and investors will also benefit from this study.

User-friendly Administration for a Diverse and Growing Therapeutic Need

As life expectancy in the developed world increases and populations age, the incidence and associated morbidity of chronic and acute pain is increasing and placing a higher level of emphasis on pain management as a quality-of-life issue for patients and their families. Responding to this trend, drug developers are increasingly turning to inhalable formulations of pain management drugs. Because it has the potential to improve drug therapy compliance, inhaled pain drug delivery addresses a key healthcare issue - one that is particularly problematic in aging populations and developing economies. Several of these development programs involve international partnerships designed to take advantage of perceived opportunities in regional markets.

What You Will Learn:

• Analyzes and evaluates inhaled pain management drugs currently in development and assesses the market potential for existing and probable future products.

• Examines inhalation device technology for commercial and development-stage devices, and evaluates product technology issues and evolving market factors for inhaled pain management therapeutics.

• Provides detailed assessments of market segments, market potential, and growth prospects.

• Forecasts the impact of new and emerging inhaled pain management drug therapeutics on healthcare markets and prescribing decisions.

• Profiles Inhaled pain management drug product market participants, their technology, product development activity, and business strategies.

• Evaluates the impact of economic, technology, and regulatory factors on market sector companies and their alliance partners.

Table of Contents

• Inhaled Pain Management
• Executive Summary
• The Pain Management Market Opportunity
• Evolution in Pain Management Guidelines
• Regional Factors in Pain Management Practice
• Pain Management Demand Drivers
• Competitive Landscape
• Factors Limiting Growth
• Inhalation Technology, Platforms and Design Factors
• Drug Formulations
• Formulation Technologies
• Excipients and Release Profiles
• Oral Inhalation Device Design Factors
• Dry Powder Inhalers
• Metered Dose Inhalers
• Nebulizers
• Intranasal Inhalation
• Intranasal Delivery Pharmacokinetics
• Intranasal Device Characteristics
• Performance Factors
• Bioavailability
• Dose Reproducibility
• Active Compound Stability
• Key Near-Term Pain Markets for Inhaled Drugs
• Breakthrough Cancer Pain
• Migraine and Cluster Headaches
• Moderate to Severe Pain
• 1Inhaled Pain Management Products
• FDA-Approved Drugs
• AstraZeneca
• GlaxoSmithKline
• Valeant
• Mylan/Roxane/Apotex
• Ketorolac
• Development-Stage Drugs
• Butorphanol
• Fentanyl
• Dihydroergotamine
• Ketamine
• Morphine
• Perchlorperazine
• Triptans
• Market Factors
• Usability and Patient Preferences
• Regulatory Issues
• Patient Compliance
• The Role of CMOs/CSOs
• Company Profiles