‘Non-antibiotic Bacterial Therapeutics ’ is a comprehensive evaluation and analysis of the technology, products and participants providing the driving force behind this evolving segment of the healthcare sector. The study is designed to provide drug company decision makers, drug delivery developers, device designers, healthcare marketers, and supply chain participants with a detailed understanding of the economics, technologies, disease segments, and commercial opportunities for non-antibiotic therapeutic substances that can treat bacterial infections that are resistant to many or most available antibiotics. Provider organization business managers, healthcare administrators and investors will also benefit from this study.
Novel Approaches Creating New Opportunities in Bacterial Therapeutics
As bacteria grow resistant to conventional antibiotics, alternatives are being investigated, including antibodies, probiotics, bacteriophages, and antimicrobial peptides currently undergoing clinical trials. The specificity of antibodies, and the inability of bacteria to develop resistance against them, make antibodies attractive, albeit expensive, alternative therapeutic agents. Bacteriophages have been used for therapy in some parts of the world. Antimicrobial peptides have long been considered as potential replacements for antibiotics but with limited success. Synthetic peptides and synthetic Antibiotic membrane-active agents might herald a shift in treatment options.
What You Will Learn:
- What are the classes of non-antibiotics drugs that can treat bacterial infections alone or in conjunction with existing antibiotics?
- What non-antibiotic bacterial therapies are in late stage development, who are the developers, and what indications are they targeting?
- What are the major factors driving demand for non-antibiotic bacterial treatments?
- What is the size of the market today, who are the market share leaders, and what will the market share be in 2028?
- What are the essential factors, technologies and market development issues for non-antibiotic bacterial therapeutics products?
- What are the significant economic, technology, and regulatory factors affecting the market for non-antibiotic bacterial therapies.
Table of Contents
- Bacterial Therapeutics Beyond Antibiotics
- Executive Summary
- Market Dynamics
- The Unmet Need
- Defining the Scope
- Recent Developments and the Need for Antibiotic Innovation
- The Evolving Landscape
- Age-appropriate Antibiotics
- Technology
- Antibodies
- Antibiotic-deactivating Enzymes
- Bacteriophages
- Antimicrobial peptides
- Antimicrobial Nanoparticles
- Antisense therapy/gene silencing
- Active extrusion of bacterial compounds by membrane pumps
- Overexpression of Multidrug resistance efflux pumps
- Siderophores
- Non-antibiotic Microbial Therapeutics - Therapies
- Antibodies
- Aerucin (Aridis)
- Zinplava/Bezlotoxumab (Merck)
- MEDI 3902 (MedImmune)
- 514G3 (XBiotech)
- Lysins
- Phages
- Antimicrobial Peptides
- Defensins
- Arenicin (Adenium Biotech)
- Murepavadin (POL7080) (Polyphor Ltd)
- Host Directed Therapies
- Univ of Hong Kong
- Case Western
- Boston's Children's Hospital
- Global Market Regulations and Standards
- North America
- US FDA
- US Centers for Disease Control
- Europe
- European Centre for Disease Prevention and Control
- Asia
- Chinese Center for Disease Control and Prevention
- National Centre for Disease Control (India)
- Company Profiles