Product Code: GVR-4-68040-116-2
Recombinant Protein Therapeutics CDMO Market Growth & Trends:
The global recombinant protein therapeutics CDMO market is expected to reach USD 52.0 billion by 2030 and is expected to expand at a CAGR of 13.95% from 2024 to 2030, according to a new report by Grand View Research, Inc. Growing technological innovations about the development of novel recombinant protein therapeutics and rising research and development for biologics are anticipated to influence the recombinant protein therapeutics CDMO industry positively. The development of novel recombinant protein therapeutics has observed significant advancements due to various technological innovations.
Recombinant proteins are bioengineered proteins produced by introducing the gene encoding the desired protein into a host cell, typically a microorganism or a mammalian cell, to express and produce the protein of interest. Several protein engineering platform technologies are currently employed to enhance the circulating half-life, targeting the precision and functionality of novel therapeutic protein drugs. These technologies also aim to boost production yield and ensure product purity.
Besides, the biopharmaceutical industry has witnessed significant growth, with an increasing number of companies investing in research and development of biologics, including recombinant proteins. This growth has been facilitated by advancements in manufacturing technologies, including adopting single-use bioreactors and other innovative production methods. For instance, in January 2024, Eurofins CDMO Alphora, Inc. announced the successful completion of its pilot-scale biologics development facility. With an expansive area of 3,300 square feet, this facility is exclusively dedicated to developing and scaling monoclonal antibodies (mAbs) and other therapeutic proteins derived from mammalian sources.
Moreover, the global increase in the prevalence of chronic and complex diseases, such as cancer, autoimmune disorders, & metabolic diseases, has increased the demand for innovative and effective therapeutic options. Recombinant protein therapeutics offer a diverse range of candidates to address these complex medical conditions. For instance, based on estimates from the American Cancer Society, it is projected that in 2023, there will be approximately 1,958,310 new cases of cancer and 609,820 cancer-related deaths in the U.S. Furthermore, according to a research article published by Oxford University, in June 2022, the number of approved and marketed antibody therapies reached 162, nearly half of which (42.6%) were being developed for the treatment of cancer.
In March 2023, the U.S. FDA granted accelerated clearance to Incyte Corporation's retifanlimab-dlwr for the treatment of adult patients with metastatic or recurrent, locally advanced Merkel Cell Carcinoma (MCC). Besides, biological therapy in cancer supports repairing, stimulating, or enhancing the immune response. Therefore, many pharmaceutical & biopharmaceutical companies are willing to invest in cancer-related novel treatments.Such advancements collectively aim to achieve a higher yield of quality products.
Recombinant Protein Therapeutics CDMO Market Report Highlights:
- The others segment dominated the market in 2023. The segment growth is driven by increasing recombinant protein therapies as a safer option than plasma-derived products owing to the potential to reduce bloodborne transmission of infectious diseases
- Based on the source, mammalian systems held the largest market share of 67.4% in 2023 attributed to an increase in the adoption of mammalian systems for sourcing recombinant proteins. Mammalian cell culture systems offer advantages in producing complex proteins with appropriate post-translational modifications, making them suitable for a wide range of therapeutic applications
- Based on indication, the metabolic disorders segment held a market share of 21.8% in 2023. The segment is driven by a growing aging population, and robust demand for pharmaceutical industry, which has contributed to its prominence in this field
- North America dominated the market with a share of 38.5% in 2023. The region has a strong R&D infrastructure and a robust biopharmaceutical industry, which has contributed to the market growth. Furthermore, the U.S. has a sophisticated and well-developed manufacturing infrastructure for biopharmaceuticals, including recombinant protein therapeutics
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation & Scope
- 1.1.1. Regional Scope
- 1.1.2. Estimates and Forecast Timeline
- 1.2. Research Methodology
- 1.3. Information Procurement
- 1.3.1. Purchased Database
- 1.3.2. GVR's InternalL Database
- 1.3.3. Secondary Sources
- 1.3.4. Primary Research
- 1.3.5. Details Of Primary Research
- 1.4. Information Or Data Analysis
- 1.4.1. Data Analysis Models
- 1.5. Market Formulation & Validation
- 1.5.1. Region Wise Market: Base Estimates
- 1.5.2. Global Market: CAGR Calculation
- 1.6. Model Details
- 1.6.1. Commodity Flow Analysis (Model 1)
- 1.6.2. Value-Chain-Based Sizing & Forecasting (Model 2)
- 1.6.3. QFD Model Sizing & Forecasting (Model 3)
- 1.6.4. Bottom-Up Approach (Model 4)
- 1.7. Market Definitions
- 1.8. List Of Secondary Sources
- 1.9. List Of Abbreviations
- 1.10. Objectives
- 1.10.1. Objective - 1
- 1.10.2. Objective - 2
- 1.10.3. Objective - 3
- 1.10.4. Objective - 4
Chapter 2. Chapter 2 Executive Summary
- 2.1. Market Snapshot
- 2.2. Segment Snapshot
- 2.3. Competitive Landscape Snapshot
Chapter 3. Recombinant Protein Therapeutics CDMO Market: Variables, Trends, & Scope
- 3.1. Market Lineage Outlook
- 3.1.1. Parent Market Outlook
- 3.1.2. Ancillary Market Outlook
- 3.2. Recombinant Protein Therapeutics CDMO Market Dynamics
- 3.2.1. Market Driver Impact Analysis
- 3.2.1.1. Rising Adoption Of Biologics And Biosimilars
- 3.2.1.2. Technological Innovations About The Development Of Novel Recombinant Protein Therapeutics
- 3.2.1.3. Increasing Rate Of Clinical Research To Boost Demand For Recombinant Protein Therapeutics
- 3.2.2. Market Restraint Analysis
- 3.2.2.1. Regulatory Hurdles
- 3.2.2.2. Challenges Related To Quality Control
- 3.3. Recombinant Protein Therapeutics CDMO Market: Analysis Tools
- 3.3.1. Porter's Five Forces Analysis
- 3.3.2. PESTEL Analysis
- 3.4. Impact Of Covid-19 On Recombinant Protein Therapeutics CDMO Market
- 3.5. Covid-19 Impact On Bioprocessing And Outsourcing
- 3.5.1. Clinical Trial Supply & Logistics Services: Impact Of Covid-19
- 3.5.2. Supply Chain
- 3.5.3. Activities By CDMOs Increased Post-Covid-19 Pandemic, Supporting The Development Of Recombinant Protein Therapeutics
- 3.5.4. Changes In The Long Term
Chapter 4. Recombinant Protein Therapeutics CDMO Market: Type Estimates & Trend Analysis
- 4.1. Definitions and Scope
- 4.1.1. Growth Hormones
- 4.1.2. Interferons
- 4.1.3. Vaccines
- 4.1.4. Immunostimulating Agents
- 4.1.5. Others
- 4.2. Segment Dashboard
- 4.3. Global Recombinant Protein Therapeutics CDMO Market Movement Analysis
- 4.4. Global Recombinant Protein Therapeutics CDMO Market Size & Trend Analysis, by Type, 2018 to 2030 (USD Million)
- 4.4.1. Growth Hormones
- 4.4.1.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 4.4.2. Interferons
- 4.4.2.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 4.4.3. Vaccines
- 4.4.3.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 4.4.4. Immunostimulating Agents
- 4.4.4.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 4.4.5. Others
- 4.4.5.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
Chapter 5. Recombinant Protein Therapeutics CDMO Market: Source Estimates & Trend Analysis
- 5.1. Definitions and Scope
- 5.1.1. Mammalian Systems
- 5.1.2. Microbial Systems
- 5.1.3. Others
- 5.2. Segment Dashboard
- 5.3. Global Recombinant Protein Therapeutics CDMO Market Movement Analysis
- 5.4. Global Recombinant Protein Therapeutics CDMO Market Size & Trend Analysis, by Source, 2018 to 2030 (USD Million)
- 5.4.1. Mammalian Systems
- 5.4.1.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 5.4.2. Microbial Systems
- 5.4.2.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 5.4.3. Others
- 5.4.3.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
Chapter 6. Recombinant Protein Therapeutics CDMO Market: Indication Estimates & Trend Analysis
- 6.1. Definitions and Scope
- 6.1.1. Oncology
- 6.1.2. Infectious Diseases
- 6.1.3. Immunological Disorders
- 6.1.4. Metabolic Disorders
- 6.1.5. Haematological Disorders
- 6.1.6. Others
- 6.2. Segment Dashboard
- 6.3. Global Recombinant Protein Therapeutics CDMO Market Movement Analysis
- 6.4. Global Recombinant Protein Therapeutics CDMO Market Size & Trend Analysis, by Indication, 2018 to 2030 (USD Million)
- 6.4.1. Oncology
- 6.4.1.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 6.4.2. Infectious Diseases
- 6.4.2.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 6.4.3. Immunological Disorders
- 6.4.3.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 6.4.4. Metabolic Disorders
- 6.4.4.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 6.4.5. Haematological Disorders
- 6.4.5.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
- 6.4.6. Others
- 6.4.6.1. Market Estimates and Forecast 2018 to 2030 (USD Million)
Chapter 7. Recombinant Protein Therapeutics CDMO Market: Regional Estimates & Trend Analysis by Type, Source, Indication
- 7.1. Regional Market Dashboard
- 7.2. Global Regional Market Snapshot
- 7.3. Market Size, & Forecasts Trend Analysis, 2018 to 2030:
- 7.4. North America
- 7.4.1. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.4.2. U.S.
- 7.4.2.1. Key Country Dynamics
- 7.4.2.2. Competitive Scenario
- 7.4.2.3. Regulatory Scenario
- 7.4.2.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.4.3. Canada
- 7.4.3.1. Key Country Dynamics
- 7.4.3.2. Competitive Scenario
- 7.4.3.3. Regulatory Scenario
- 7.4.3.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.5. Europe
- 7.5.1. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.5.2. UK
- 7.5.2.1. Key Country Dynamics
- 7.5.2.2. Competitive Scenario
- 7.5.2.3. Regulatory Scenario
- 7.5.2.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.5.3. Germany
- 7.5.3.1. Key Country Dynamics
- 7.5.3.2. Competitive Scenario
- 7.5.3.3. Regulatory Scenario
- 7.5.3.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.5.4. France
- 7.5.4.1. Key Country Dynamics
- 7.5.4.2. Competitive Scenario
- 7.5.4.3. Regulatory Scenario
- 7.5.4.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.5.5. Italy
- 7.5.5.1. Key Country Dynamics
- 7.5.5.2. Competitive Scenario
- 7.5.5.3. Regulatory Scenario
- 7.5.5.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.5.6. Spain
- 7.5.6.1. Key Country Dynamics
- 7.5.6.2. Competitive Scenario
- 7.5.6.3. Regulatory Scenario
- 7.5.6.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.5.7. Denmark
- 7.5.7.1. Key Country Dynamics
- 7.5.7.2. Competitive Scenario
- 7.5.7.3. Regulatory Scenario
- 7.5.7.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.5.8. Sweden
- 7.5.8.1. Key Country Dynamics
- 7.5.8.2. Competitive Scenario
- 7.5.8.3. Regulatory Scenario
- 7.5.8.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.5.9. Norway
- 7.5.9.1. Key Country Dynamics
- 7.5.9.2. Competitive Scenario
- 7.5.9.3. Regulatory Scenario
- 7.5.9.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.6. Asia Pacific
- 7.6.1. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.6.2. Japan
- 7.6.2.1. Key Country Dynamics
- 7.6.2.2. Competitive Scenario
- 7.6.2.3. Regulatory Scenario
- 7.6.2.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.6.3. China
- 7.6.3.1. Key Country Dynamics
- 7.6.3.2. Competitive Scenario
- 7.6.3.3. Regulatory Scenario
- 7.6.3.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.6.4. India
- 7.6.4.1. Key Country Dynamics
- 7.6.4.2. Competitive Scenario
- 7.6.4.3. Regulatory Scenario
- 7.6.4.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.6.5. Australia
- 7.6.5.1. Key Country Dynamics
- 7.6.5.2. Competitive Scenario
- 7.6.5.3. Regulatory Scenario
- 7.6.5.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.6.6. Thailand
- 7.6.6.1. Key Country Dynamics
- 7.6.6.2. Competitive Scenario
- 7.6.6.3. Regulatory Scenario
- 7.6.6.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.6.7. South Korea
- 7.6.7.1. Key Country Dynamics
- 7.6.7.2. Competitive Scenario
- 7.6.7.3. Regulatory Scenario
- 7.6.7.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.7. Latin America
- 7.7.1. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.7.2. Brazil
- 7.7.2.1. Key Country Dynamics
- 7.7.2.2. Competitive Scenario
- 7.7.2.3. Regulatory Scenario
- 7.7.2.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.7.3. Mexico
- 7.7.3.1. Key Country Dynamics
- 7.7.3.2. Competitive Scenario
- 7.7.3.3. Regulatory Scenario
- 7.7.3.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.7.4. Argentina
- 7.7.4.1. Key Country Dynamics
- 7.7.4.2. Competitive Scenario
- 7.7.4.3. Regulatory Scenario
- 7.7.4.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.8. MEA
- 7.8.1. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.8.2. South Africa
- 7.8.2.1. Key Country Dynamics
- 7.8.2.2. Competitive Scenario
- 7.8.2.3. Regulatory Scenario
- 7.8.2.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.8.3. Saudi Arabia
- 7.8.3.1. Key Country Dynamics
- 7.8.3.2. Competitive Scenario
- 7.8.3.3. Regulatory Scenario
- 7.8.3.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.8.4. UAE
- 7.8.4.1. Key Country Dynamics
- 7.8.4.2. Competitive Scenario
- 7.8.4.3. Regulatory Scenario
- 7.8.4.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
- 7.8.5. Kuwait
- 7.8.5.1. Key Country Dynamics
- 7.8.5.2. Competitive Scenario
- 7.8.5.3. Regulatory Scenario
- 7.8.5.4. Market Estimates and Forecast, 2018 - 2030 (USD Million)
Chapter 8. Competitive Landscape
- 8.1. Company Categorization
- 8.2. Recombinant Protein Therapeutics CDMO Market Share Analysis, 2023
- 8.3. Major Deals and Strategic Alliances Analysis
- 8.3.1. Strategy Mapping
- 8.3.2. Expansion
- 8.3.3. Partnerships
- 8.3.4. Acquisitions
- 8.4. Vendor Landscape
- 8.4.1. Key company market share analysis, 2023
- 8.4.2. Richter-Helm BioLogics
- 8.4.2.1. Company overview
- 8.4.2.2. Financial performance
- 8.4.2.3. Product benchmarking
- 8.4.2.4. Strategic initiatives
- 8.4.3. Lonza
- 8.4.3.1. Company overview
- 8.4.3.2. Financial performance
- 8.4.3.3. Product benchmarking
- 8.4.3.4. Strategic initiatives
- 8.4.4. Catalent, Inc
- 8.4.4.1. Company overview
- 8.4.4.2. Financial performance
- 8.4.4.3. Product benchmarking
- 8.4.4.4. Strategic initiatives
- 8.4.5. FUJIFILM Diosynth Biotechnologies
- 8.4.5.1. Company overview
- 8.4.5.2. Financial performance
- 8.4.5.3. Product benchmarking
- 8.4.5.4. Strategic initiatives
- 8.4.6. WuXi Biologics
- 8.4.6.1. Company overview
- 8.4.6.2. Financial performance
- 8.4.6.3. Product benchmarking
- 8.4.6.4. Strategic initiatives
- 8.4.7. Curia Global, Inc.
- 8.4.7.1. Company overview
- 8.4.7.2. Financial performance
- 8.4.7.3. Product benchmarking
- 8.4.7.4. Strategic initiatives
- 8.4.8. Batavia Biosciences B.V.
- 8.4.8.1. Company overview
- 8.4.8.2. Financial performance
- 8.4.8.3. Product benchmarking
- 8.4.8.4. Strategic initiatives
- 8.4.9. HALIX B.V.
- 8.4.9.1. Company overview
- 8.4.9.2. Financial performance
- 8.4.9.3. Product benchmarking
- 8.4.9.4. Strategic initiatives
- 8.4.10. BIOVIAN
- 8.4.10.1. Company overview
- 8.4.10.2. Financial performance
- 8.4.10.3. Product benchmarking
- 8.4.10.4. Strategic initiatives
- 8.4.11. Enzene Biosciences Ltd
- 8.4.11.1. Company overview
- 8.4.11.2. Financial performance
- 8.4.11.3. Product benchmarking
- 8.4.11.4. Strategic initiatives