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市場調查報告書
商品編碼
1654380
美國醫藥市場規模、佔有率和趨勢分析報告:按分子、產品類型、給藥途徑、疾病、年齡層、分銷管道、細分預測,2025-2030 年U.S. Pharmaceutical Market Size, Share & Trends Analysis Report By Molecule, By Product, By Type, By Route Of Administration, By Disease, By Age Group, By Distribution Channel, And Segment Forecasts, 2025 - 2030 |
預計 2024 年美國醫藥市場規模為 6,343.2 億美元,到 2030 年將達到 8,839.7 億美元,2025 年至 2030 年的複合年成長率為 5.72%。這種成長是由於慢性病患病率上升、老齡人口成長、政府機構增加醫療保健支出以及普遍努力提高藥品的可負擔性和可獲得性。
由於治療方法的進步和強大的產品平臺,美國製藥業正在經歷強勁成長。標靶治療、生技藥品和個人化醫療的發展正在重塑治療模式,並為癌症、自體免疫和遺傳性疾病等複雜疾病提供更有效的解決方案。基因療法和基於 RNA 的療法正在獲得 FDA核准,例如治療遺傳性視網膜疾病和某些癌症,有助於推動產業發展。用於治療某些癌症的CAR-T細胞療法等尖端藥物的核准表明市場對精準醫療的關注度日益提高,為治療以前無法治癒的疾病帶來了希望。顯著的進展包括免疫腫瘤療法的持續進步,重新定義了癌症治療。
在美國醫藥市場,GLP-1受體促效劑及GLP-1/GIP雙重促效劑的突破性臨床結果為肥胖治療樹立了新的標準。 GLP-1受體促效劑和GLP-1/GIP雙重促效劑作為將帶來前所未有的臨床效果的突破性治療方法而備受關注。這些藥物,包括Semaglutide和替澤帕肽,已被證明可以使體重減輕高達 25%,遠遠超過先前只能達到 7% 左右減重效果的藥物類別。這項突破重塑了患者和醫療保健提供者的肥胖治療模式,為長期難以控制的疾病提供了可行的醫療解決方案。加上數位健康工具的進步,這些治療現在已成為將藥物治療與技術、行為指導和個人化介入相結合的綜合護理模式的一部分。這種綜合方法不僅能解決肥胖問題,還能改善患者的整體治療效果,為克服美國重大公共衛生挑戰指明了方向。
美國醫藥品研究開發費用是市場成長的重要驅動力,該領域不斷投資於發現和開發新的治療方法。 2023年,美國製藥公司在研發上的投入將超過800億美元,而且這個數字每年都在增加。強生、默克、禮來等大公司認知到開發創新藥物以應對人口老化和慢性病增加的重要性,並將公司收益的很大一部分用於研發。
如此高水準的投資正在推動腫瘤學、免疫學和罕見疾病等多個領域的突破性治療方法的發現。根據牛津學術雜誌的報導,到2023年,美國的藥品支出將增加13.6%,達到7,225億美元。這一成長是由利用率增加 6.5%、新藥增加 4.2% 以及價格上漲 2.9% 所推動的。 2023 年最暢銷的藥物是Semaglutide,其次是Adalimumab和Apixaban。此外,到 2023 年,非聯邦醫院的藥品支出預計將下降 1.1% 至 371 億美元,而診所的藥品支出將增加 15.0% 至 1,357 億美元。診所的成長是由利用率的提高所推動的,僅受到新產品和價格變化的輕微影響。對於非聯邦醫院,利用率降低導致支出降低,但新藥和價格的影響很小。預計 2024 年將推出的幾種新藥將繼續推動支出,尤其是在專科、內分泌和腫瘤治療領域。
新型創新藥物不斷湧入市場也是美國醫藥市場發展的主要動力之一。隨著患者和醫療保健提供者越來越意識到新療法的有效性,對具有更好結果和更少副作用的最先進治療的需求也日益增加。特別是生技藥品、基因治療、免疫治療對癌症、自體免疫疾病等的應用日益廣泛。例如,單株抗體(如用於免疫腫瘤學的抗體)的快速應用已經改變了治療格局,市場領導者 Keytruda 和Opdivo 的與前一年同期比較實現了令人印象深刻的成長。近日,2024年9月,API研發中心接受了1,400萬美元的戰略資金,旨在加強美國製藥獨立性。這筆資金將支持美國關鍵活性藥物原料藥(API) 製造能力的發展,提高供應鏈的彈性並減少對海外來源的依賴。這項舉措符合加強國內生產、提高國家安全和確保持續獲得基本藥物的努力。
然而,主要藥物的專利到期是美國製藥業發展的一大限制因素。當專利到期時,學名藥往往會進入市場,導致品牌藥銷售量急劇下降。例如,2023年1月,艾伯維的重磅藥物Humira(Adalimumab)的專利將到期,該藥物年銷售額超過200億美元,為生物學名藥的競爭打開了大門。從品牌藥物轉變為學名藥的轉變將減少原產公司的市場佔有率,從而嚴重影響其收益來源。整體市場動態也將受到學名藥定價壓力的影響,迫使原產公司降低價格或尋找新的市場利基。這種轉變在生技藥品市場尤為明顯,其中Enbrel和Herceptin等主要產品的專利已到期,為更便宜的替代品鋪平了道路。
The U.S. pharmaceutical market size was estimated at USD 634.32 billion in 2024 and is expected to grow at a CAGR of 5.72% from 2025 to 2030, to reach an estimated value of USD 883.97 billion by 2030. This growth can be attributed to the rising prevalence of chronic diseases, increasing geriatric population, growing healthcare expenditure by government organizations, and extensive efforts to improve the affordability & accessibility of pharmaceuticals.
The U.S. pharmaceutical industry has experienced significant growth due to advancements in therapeutics and a robust product pipeline. The development of targeted therapies, biologics, and personalized medicine has reshaped treatment model, offering more effective solutions for complex conditions such as cancer, autoimmune diseases, and genetic disorders. Gene therapies and RNA-based treatments, like those for inherited retinal diseases and certain types of cancers, have gained FDA approvals, contributing to the industry's momentum. The approval of cutting-edge drugs such as CAR-T cell therapies for certain cancers exemplifies the market's growing focus on precision medicine, offering hope for previously untreatable conditions. A notable advancement is the continued progression in immuno-oncology treatments, which are redefining cancer care.
In the U.S. market for pharmaceuticals, the transformative clinical outcomes of GLP-1 receptor agonists and GLP-1/GIP dual agonists, have set a new benchmark for obesity treatment. As they are emerged as transformative therapies, delivering unprecedented clinical results. These medications, such as semaglutide and tirzepatide, have demonstrated weight loss of up to 25%, significantly outperforming earlier drug classes, which achieved only about 7% weight reduction. This breakthrough has reshaped the obesity treatment paradigm for both patients and providers, offering a viable medical solution to a condition long viewed as difficult to manage. Coupled with advances in digital health tools, these therapies are part of integrated care models that combine pharmacological treatments with technology, behavioral coaching, and personalized interventions. This comprehensive approach not only addresses obesity but also improves overall patient outcomes, presenting a credible pathway to overcoming a major public health challenge in the U.S.
Pharmaceutical R&D spending in the U.S. has been a pivotal driver of market growth, with the sector continuously investing in the discovery and development of new therapies. In 2023, pharmaceutical companies in the U.S. spent over USD 80 billion on R&D, a figure that continues to rise annually. Major companies like Johnson & Johnson, Merck, and Eli Lilly have earmarked significant portions of their revenues to R&D, recognizing the importance of developing innovative drugs to meet the demands of an aging population and the increasing prevalence of chronic diseases.
This high level of investment fuels the discovery of breakthrough therapies across various segments, including oncology, immunology, and rare diseases. According to an article by oxford Academic, in 2023, U.S. pharmaceutical spending rose by 13.6% to reach USD 722.5 billion. This increase was driven by a 6.5% rise in utilization, a 4.2% boost from new drugs, and a 2.9% uptick in prices. The top-selling drug of 2023 was semaglutide, followed by adalimumab and apixaban. Furthermore, In 2023, drug spending in nonfederal hospitals decreased by 1.1%, totaling USD 37.1 billion, while expenditures in clinics increased by 15.0% to USD 135.7 billion. Clinic growth was driven by higher utilization, with a minor impact from new products and price changes. In nonfederal hospitals, lower utilization led to reduced spending, while new drugs and prices had a modest influence. Several new drugs expected in 2024, especially in specialty, endocrine, and cancer treatments, will continue to drive spending.
The growing market adoption of innovative and modern medicines is another key driver of the U.S. pharmaceutical market. As patients and healthcare providers become more aware of the effectiveness of new treatments, there is an increasing demand for cutting-edge therapies that offer better outcomes and fewer side effects. The uptake of biologics, gene therapies, and immunotherapies in oncology, autoimmune diseases, and other areas has been particularly notable. For example, the rapid adoption of monoclonal antibodies, such as those used in immuno-oncology, has transformed the treatment landscape, with market leaders like Keytruda and Opdivo showing impressive year-on-year sales growth. Recently, in September 2024, the API Innovation Center received USD 14 million in strategic funding aimed at strengthening U.S. pharmaceutical independence. The funding will support the development of critical Active Pharmaceutical Ingredients (API) manufacturing capabilities within the U.S., enhancing resilience in the supply chain and reducing reliance on foreign sources. This initiative aligns with efforts to bolster domestic production, improve national security, and ensure consistent access to essential medicines.
However, Patent expiration of key pharmaceutical drugs has emerged as a significant restraint for the growth of the U.S. pharmaceutical industry. Once patents expire, generic versions of these drugs can enter the market, often leading to a sharp decline in sales for the original branded drugs. For instance, in January 2023, the patent for AbbVie's blockbuster drug Humira (adalimumab), which generated over USD 20 billion in annual sales, expired, allowing biosimilars to compete. The shift from branded to generic drugs reduces the market share of originator companies and significantly impacts their revenue streams. The overall market dynamics are also affected by the pricing pressure brought on by these generics, forcing branded companies to reduce prices or find new market niches. This change is particularly evident in the biologics market, where patents for key products like Enbrel and Herceptin have expired, opening the door for cheaper alternatives.
U.S. Pharmaceutical Market Report Segmentation
This report forecasts revenue growth and provides an analysis on the latest trends in each of the sub-segments from 2018 to 2030. For the purpose of this report, Grand View Research has segmented the U.S. pharmaceutical market report based on molecule, product, type, disease, route of administration, age group, and distribution channel: