Product Code: GVR-4-68040-384-0
Market Size & Trends:
The global acute myeloid leukemia treatment market size was estimated at USD 3.47 billion in 2024 and is projected to grow at a CAGR of 10.6% from 2025 to 2030. Rising incidences of acute myeloid leukemia and increasing need for advanced therapeutics are attributed to factors such as genetic mutations, unhealthy lifestyles, continued exposure to hazardous chemicals such as benzene, and radiation exposure. Moreover, the increasing geriatric population base and growing unmet healthcare needs are expected to boost market growth further.
Advancements in targeted therapies have been at the forefront of the progress in Acute Myeloid Leukemia (AML) treatment so far. In recent years, there has been substantial development in therapies such as BCL2 inhibitors, IDH inhibitors, and FLT3 inhibitors. These therapies provide personalized treatment options tailored to specific genetic mutations, resulting in improved outcomes for patients. For instance, in July 2023, the FDA approved quizartinib (Vanflyta) for newly diagnosed FLT3-ITD positive acute myeloid leukemia in the U.S., enhancing treatment options alongside standard chemotherapy.
Combinations such as venetoclax with azacitidine or other hypomethylating agents have shown promising results in enhancing survival rates for AML patients. Additional research interest focuses on incorporating venetoclax into the traditional 7+3 chemotherapy regimen, which aims to maximize treatment efficacy. Such innovative approaches indicate a growing commitment to developing multifaceted treatment strategies that promise to improve patient outcomes.
Moreover, the exploration of immunotherapies, including CAR-T cell therapies, represents a transformative trend in AML treatment. These therapies are designed to bolster the immune system's response to cancer cells, thus providing new hope for patients who have limited options. The advancements in the understanding of genetic mutations associated with AML have further contributed to personalized treatment strategies, such as targeting specific mutations such as KMT2A and NPM1 with menin inhibitors.
The growing incidence of AML, driven by factors such as genetic mutations, unhealthy lifestyles, and environmental hazards, underscores the urgent need for innovative therapies. According to the American Cancer Society, approximately 22,010 individuals are estimated to be diagnosed with AML in 2025, further highlighting the rising demand for effective treatment options. In December 2023, scientists at the University of Montreal secured a USD 6 million grant from Genome Canada to develop a novel Cyclin K degrader for high-risk acute myeloid leukemia patients, aiming to enhance treatment outcomes and stimulate economic growth in Canada. The development of innovative therapies for high-risk patients, along with substantial global investments in research and development, is expected to drive market growth. Furthermore, partnerships between pharmaceutical companies and research institutions are enhancing the pace of new AML treatment development.
Global Acute Myeloid Leukemia Treatment Market Report Segmentation
This report forecasts revenue growth at global, regional, and country levels and provides an analysis of the latest industry trends in each of the sub-segments from 2018 to 2030. For this study, Grand View Research has segmented the global acute myeloid leukemia treatment market report based on disease, treatment, route of administration, end use, and region:
- Disease Outlook (Revenue, USD Million, 2018 - 2030)
- Myeloblastic Leukemia
- Myelomonocytic Leukemia
- Promyelocytic Leukemia
- Monocytic Leukemia
- Other Diseases
- Treatment Outlook (Revenue, USD Million, 2018 - 2030)
- Chemotherapy
- Anti-metabolites
- Alkylating Agents
- Anthracycline Drugs
- Others
- Targeted Therapy
- FLT3 Inhibitors
- Rydapt
- Vanflyta
- Xospata
- IDH Inhibitors
- Tibsovo
- Rezlidhia
- Idhifa
- Mylotarg
- BCL-2 Inhibitor
- Hedgehog Pathway Inhibitor
- Immunotherapy
- Bispecific Antibodies
- Antibody-drug Conjugates
- Immune Checkpoint Inhibitors
- Chimeric Antigen Receptor (CAR) T-cell Therapy
- Other Treatments
- Route of Administration Outlook (Revenue, USD Million, 2018 - 2030)
- Parenteral
- Oral
- End Use Outlook (Revenue, USD Million, 2018 - 2030)
- Hospitals and Clinics
- Specialty Centers
- Homecare Setting
- Ambulatory Care Centers
- Regional Outlook (Revenue, USD Million, 2018 - 2030)
- North America
- Europe
- UK
- Germany
- France
- Italy
- Spain
- Denmark
- Sweden
- Norway
- Asia Pacific
- Japan
- China
- India
- Australia
- South Korea
- Thailand
- Latin America
- Middle East & Africa
- South Africa
- Saudi Arabia
- UAE
- Kuwait
Table of Contents
Chapter 1. Methodology and Scope
- 1.1. Market Segmentation & Scope
- 1.2. Segment Definitions
- 1.2.1. Disease
- 1.2.2. Treatment
- 1.2.3. Route of Administration
- 1.2.4. End Use
- 1.3. Estimates and Forecast Timeline
- 1.4. Research Methodology
- 1.5. Information Procurement
- 1.5.1. Purchased Database
- 1.5.2. GVR's Internal Database
- 1.5.3. Secondary Sources
- 1.5.4. Primary Research
- 1.6. Information Analysis
- 1.6.1. Data Analysis Models
- 1.7. Market Formulation & Data Visualization
- 1.8. Model Details
- 1.8.1. Commodity Flow Analysis
- 1.9. List of Secondary Sources
- 1.10. Objectives
Chapter 2. Executive Summary
- 2.1. Market Snapshot
- 2.2. Segment Snapshot
- 2.3. Competitive Landscape Snapshot
Chapter 3. Acute Myeloid Leukemia Treatment Market Variables, Trends, & Scope
- 3.1. Market Lineage Outlook
- 3.2. Market Dynamics
- 3.2.1. Market Driver Analysis
- 3.2.2. Market Restraint Analysis
- 3.3. Business Environment Analysis
- 3.3.1. Industry Analysis - Porter's Five Forces Analysis
- 3.3.1.1. Supplier Power
- 3.3.1.2. Buyer Power
- 3.3.1.3. Substitution Threat
- 3.3.1.4. Threat of New Entrants
- 3.3.1.5. Competitive Rivalry
- 3.3.2. PESTLE Analysis
- 3.4. Pipeline Analysis
Chapter 4. Acute Myeloid Leukemia Treatment Market: Disease Business Analysis
- 4.1. Disease Market Share, 2024 & 2030
- 4.2. Disease Segment Dashboard
- 4.3. Market Size & Forecasts and Trend Analysis, by Treatment, 2018 to 2030 (USD Million)
- 4.4. Myeloblastic Leukemia
- 4.4.1. Myeloblastic Leukemia Market, 2018 - 2030 (USD Million)
- 4.5. Myelomonocytic Leukemia
- 4.5.1. Myelomonocytic Leukemia Market, 2018 - 2030 (USD Million)
- 4.6. Promyelocytic Leukemia
- 4.6.1. Promyelocytic Leukemia Market, 2018 - 2030 (USD Million)
- 4.7. Monocytic Leukemia
- 4.7.1. Monocytic Leukemia Market, 2018 - 2030 (USD Million)
- 4.8. Other Diseases
- 4.8.1. Other Diseases Market, 2018 - 2030 (USD Million)
Chapter 5. Acute Myeloid Leukemia Treatment Market: Treatment Business Analysis
- 5.1. Treatment Market Share, 2024 & 2030
- 5.2. Treatment Segment Dashboard
- 5.3. Market Size & Forecasts and Trend Analysis, by Treatment, 2018 to 2030 (USD Million)
- 5.4. Chemotherapy
- 5.4.1. Chemotherapy Market, 2018 - 2030 (USD Million)
- 5.4.2. Anti-metabolites
- 5.4.3. Anti-metabolites Market, 2018 - 2030 (USD Million)
- 5.4.4. Alkylating Agents
- 5.4.5. Alkylating Agents Market, 2018 - 2030 (USD Million)
- 5.4.6. Anthracycline Drugs
- 5.4.7. Anthracycline Drugs Market, 2018 - 2030 (USD Million)
- 5.4.8. Others
- 5.4.9. Others Market, 2018 - 2030 (USD Million)
- 5.5. Targeted Therapy
- 5.5.1. Targeted Therapy Market, 2018 - 2030 (USD Million)
- 5.5.2. FLT3 Inhibitors
- 5.5.3. FLT3 Inhibitors Market, 2018 - 2030 (USD Million)
- 5.5.3.1. Rydapt
- 5.5.3.1.1. Rydapt Market, 2018 - 2030 (USD Million)
- 5.5.3.2. Vanflyta
- 5.5.3.2.1. Vanflyta Market, 2018 - 2030 (USD Million)
- 5.5.3.3. Xospata
- 5.5.3.3.1. Xospata Market, 2018 - 2030 (USD Million)
- 5.5.4. IDH Inhibitors
- 5.5.5. IDH Inhibitors Market, 2018 - 2030 (USD Million)
- 5.5.5.1. Tibsovo
- 5.5.5.1.1. Tibsovo Market, 2018 - 2030 (USD Million)
- 5.5.5.2. Rezlidhia
- 5.5.5.2.1. Rezlidhia Market, 2018 - 2030 (USD Million)
- 5.5.5.3. Idhifa
- 5.5.5.3.1. Idhifa Market, 2018 - 2030 (USD Million)
- 5.5.6. Mylotarg
- 5.5.6.1. Mylotarg Market, 2018 - 2030 (USD Million)
- 5.5.7. BCL-2 Inhibitor
- 5.5.7.1. BCL-2 Inhibitor Market, 2018 - 2030 (USD Million)
- 5.5.8. Hedgehog Pathway Inhibitor
- 5.5.8.1. Hedgehog Pathway Inhibitor Market, 2018 - 2030 (USD Million)
- 5.6. Immunotherapy
- 5.6.1. Immunotherapy Market, 2018 - 2030 (USD Million)
- 5.6.2. Bispecific Antibodies
- 5.6.2.1. Bispecific Antibodies Market, 2018 - 2030 (USD Million)
- 5.6.3. Antibody-drug Conjugates
- 5.6.3.1. Antibody-drug Conjugates Market, 2018 - 2030 (USD Million)
- 5.6.4. Immune Checkpoint Inhibitors
- 5.6.4.1. Immune Checkpoint Inhibitors Market, 2018 - 2030 (USD Million)
- 5.6.5. Chimeric Antigen Receptor (CAR) T-cell Therapy
- 5.6.5.1. Chimeric Antigen Receptor (CAR) T-cell Therapy Market, 2018 - 2030 (USD Million)
- 5.7. Other Treatments
- 5.7.1. Other Treatments Market, 2018 - 2030 (USD Million)
Chapter 6. Acute Myeloid Leukemia Treatment Market: Route of Administration Business Analysis
- 6.1. Route of Administration Market Share, 2024 & 2030
- 6.2. Route of Administration Segment Dashboard
- 6.3. Market Size & Forecasts and Trend Analysis, by Route of Administration, 2018 to 2030 (USD Million)
- 6.4. Parenteral
- 6.4.1. Parenteral Market, 2018 - 2030 (USD Million)
- 6.5. Oral
- 6.5.1. Oral Market, 2018 - 2030 (USD Million)
Chapter 7. Acute Myeloid Leukemia Treatment Market: End Use Business Analysis
- 7.1. End Use Market Share, 2024 & 2030
- 7.2. End Use Segment Dashboard
- 7.3. Market Size & Forecasts and Trend Analysis, by End Use, 2018 to 2030 (USD Million)
- 7.4. Hospitals and Clinics
- 7.4.1. Hospitals and Clinics Market, 2018 - 2030 (USD Million)
- 7.5. Specialty Centers
- 7.5.1. Specialty Centers Market, 2018 - 2030 (USD Million)
- 7.6. Homecare Setting
- 7.6.1. Homecare Setting Market, 2018 - 2030 (USD Million)
- 7.7. Ambulatory Care Centers
- 7.7.1. Ambulatory Care Centers Market, 2018 - 2030 (USD Million)
Chapter 8. Acute Myeloid Leukemia Treatment Market: Regional Estimates & Trend Analysis
- 8.1. Regional Market Share Analysis, 2024 & 2030
- 8.2. Regional Market Dashboard
- 8.3. Market Size, & Forecasts Trend Analysis, 2018 to 2030:
- 8.4. North America
- 8.4.1. North America Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, By Country, 2018 - 2030 (USD Million)
- 8.4.2. U.S.
- 8.4.2.1. Key Country Dynamics
- 8.4.2.2. Regulatory Framework
- 8.4.2.3. Competitive Insights
- 8.4.2.4. U.S. Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.4.3. Canada
- 8.4.3.1. Key Country Dynamics
- 8.4.3.2. Regulatory Framework
- 8.4.3.3. Competitive Insights
- 8.4.3.4. Canada Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.4.4. Mexico
- 8.4.4.1. Key Country Dynamics
- 8.4.4.2. Regulatory Framework
- 8.4.4.3. Competitive Insights
- 8.4.4.4. Mexico Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.5. Europe
- 8.5.1. Europe Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, By Country, 2018 - 2030 (USD Million)
- 8.5.2. UK
- 8.5.2.1. Key Country Dynamics
- 8.5.2.2. Regulatory Framework
- 8.5.2.3. Competitive Insights
- 8.5.2.4. UK Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.5.3. Germany
- 8.5.3.1. Key Country Dynamics
- 8.5.3.2. Regulatory Framework
- 8.5.3.3. Competitive Insights
- 8.5.3.4. Germany Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.5.4. France
- 8.5.4.1. Key Country Dynamics
- 8.5.4.2. Regulatory Framework
- 8.5.4.3. Competitive Insights
- 8.5.4.4. France Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.5.5. Italy
- 8.5.5.1. Key Country Dynamics
- 8.5.5.2. Regulatory Framework
- 8.5.5.3. Competitive Insights
- 8.5.5.4. Italy Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.5.6. Spain
- 8.5.6.1. Key Country Dynamics
- 8.5.6.2. Regulatory Framework
- 8.5.6.3. Competitive Insights
- 8.5.6.4. Spain Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.5.7. Norway
- 8.5.7.1. Key Country Dynamics
- 8.5.7.2. Regulatory Framework
- 8.5.7.3. Competitive Insights
- 8.5.7.4. Norway Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.5.8. Denmark
- 8.5.8.1. Key Country Dynamics
- 8.5.8.2. Regulatory Framework
- 8.5.8.3. Competitive Insights
- 8.5.8.4. Denmark Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.5.9. Sweden
- 8.5.9.1. Key Country Dynamics
- 8.5.9.2. Regulatory Framework
- 8.5.9.3. Competitive Insights
- 8.5.9.4. Sweden Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.6. Asia Pacific
- 8.6.1. Asia Pacific Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, By Country, 2018 - 2030 (USD Million)
- 8.6.2. Japan
- 8.6.2.1. Key Country Dynamics
- 8.6.2.2. Regulatory Framework
- 8.6.2.3. Competitive Insights
- 8.6.2.4. Japan Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.6.3. China
- 8.6.3.1. Key Country Dynamics
- 8.6.3.2. Regulatory Framework
- 8.6.3.3. Competitive Insights
- 8.6.3.4. China Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.6.4. India
- 8.6.4.1. Key Country Dynamics
- 8.6.4.2. Regulatory Framework
- 8.6.4.3. Competitive Insights
- 8.6.4.4. India Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.6.5. South Korea
- 8.6.5.1. Key Country Dynamics
- 8.6.5.2. Regulatory Framework
- 8.6.5.3. Competitive Insights
- 8.6.5.4. South Korea Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.6.6. Australia
- 8.6.6.1. Key Country Dynamics
- 8.6.6.2. Regulatory Framework
- 8.6.6.3. Competitive Insights
- 8.6.6.4. Australia Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.6.7. Thailand
- 8.6.7.1. Key Country Dynamics
- 8.6.7.2. Regulatory Framework
- 8.6.7.3. Competitive Insights
- 8.6.7.4. Thailand Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.7. Latin America
- 8.7.1. Latin America Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, By Country, 2018 - 2030 (USD Million)
- 8.7.2. Brazil
- 8.7.2.1. Key Country Dynamics
- 8.7.2.2. Regulatory Framework
- 8.7.2.3. Competitive Insights
- 8.7.2.4. Brazil Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.7.3. Argentina
- 8.7.3.1. Key Country Dynamics
- 8.7.3.2. Regulatory Framework
- 8.7.3.3. Competitive Insights
- 8.7.3.4. Argentina Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.8. MEA
- 8.8.1. MEA Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, By Country, 2018 - 2030 (USD Million)
- 8.8.2. South Africa
- 8.8.2.1. Key Country Dynamics
- 8.8.2.2. Regulatory Framework
- 8.8.2.3. Competitive Insights
- 8.8.2.4. South Africa Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.8.3. Saudi Arabia
- 8.8.3.1. Key Country Dynamics
- 8.8.3.2. Regulatory Framework
- 8.8.3.3. Competitive Insights
- 8.8.3.4. Saudi Arabia Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.8.4. UAE
- 8.8.4.1. Key Country Dynamics
- 8.8.4.2. Regulatory Framework
- 8.8.4.3. Competitive Insights
- 8.8.4.4. UAE Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
- 8.8.5. Kuwait
- 8.8.5.1. Key Country Dynamics
- 8.8.5.2. Regulatory Framework
- 8.8.5.3. Competitive Insights
- 8.8.5.4. Kuwait Acute Myeloid Leukemia Treatment Market Estimates And Forecasts, 2018 - 2030 (USD Million)
Chapter 9. Competitive Landscape
- 9.1. Participant Overview
- 9.2. Company Market Position Analysis
- 9.3. Company Categorization
- 9.4. Strategy Mapping
- 9.5. Company Profiles/Listing
- 9.5.1. Astellas Pharma Inc.
- 9.5.1.1. Overview
- 9.5.1.2. Financial Performance
- 9.5.1.3. Product Benchmarking
- 9.5.1.4. Strategic Initiatives
- 9.5.2. Bristol-Myers Squibb Company
- 9.5.2.1. Overview
- 9.5.2.2. Financial Performance
- 9.5.2.3. Product Benchmarking
- 9.5.2.4. Strategic Initiatives
- 9.5.3. DAIICHI SANKYO COMPANY, LIMITED
- 9.5.3.1. Overview
- 9.5.3.2. Financial Performance
- 9.5.3.3. Product Benchmarking
- 9.5.3.4. Strategic Initiatives
- 9.5.4. Jazz Pharmaceuticals plc
- 9.5.4.1. Overview
- 9.5.4.2. Financial Performance
- 9.5.4.3. Product Benchmarking
- 9.5.4.4. Strategic Initiatives
- 9.5.5. Novartis AG
- 9.5.5.1. Overview
- 9.5.5.2. Financial Performance
- 9.5.5.3. Product Benchmarking
- 9.5.5.4. Strategic Initiatives
- 9.5.6. Otsuka Pharmaceuticals Co.,Ltd.
- 9.5.6.1. Overview
- 9.5.6.2. Financial Performance
- 9.5.6.3. Product Benchmarking
- 9.5.6.4. Strategic Initiatives
- 9.5.7. Pfizer Inc.
- 9.5.7.1. Overview
- 9.5.7.2. Financial Performance
- 9.5.7.3. Product Benchmarking
- 9.5.7.4. Strategic Initiatives
- 9.5.8. Rigel Pharmaceuticals, Inc.
- 9.5.8.1. Overview
- 9.5.8.2. Financial Performance
- 9.5.8.3. Product Benchmarking
- 9.5.8.4. Strategic Initiatives
- 9.5.9. Merck KGaA
- 9.5.9.1. Overview
- 9.5.9.2. Financial Performance
- 9.5.9.3. Product Benchmarking
- 9.5.9.4. Strategic Initiatives
- 9.5.10. Sanofi
- 9.5.10.1. Overview
- 9.5.10.2. Financial Performance
- 9.5.10.3. Product Benchmarking
- 9.5.10.4. Strategic Initiatives