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市場調查報告書
商品編碼
1519761
2024-2032 年按產品、類型、應用、最終用途和地區分類的器官晶片市場報告Organ-on-chip Market Report by Offering, Type, Application, End Use, and Region 2024-2032 |
IMARC Group年,全球器官晶片市場規模達到6,160萬美元。該市場的推動力是其在加強藥物研發方面的關鍵作用,受到技術進步、協作努力以及透過醫學研究中更準確和人性化的替代方案減少動物試驗的監管和道德日益重視的刺激。
主要市場促進因素:由於製藥和生物技術領域對更準確和道德的研究方法的需求,晶片器官市場正在迅速擴張。
主要市場趨勢:3D生物列印和微流體等技術進步正在徹底改變晶片器官模型,提高其準確性和適用性。
地理趨勢:北美在強大的研究基礎設施和積極的監管政策的支持下引領市場;然而,由於生物技術投資不斷增加,歐洲和亞太地區正迅速迎頭趕上。
競爭格局:器官晶片行業的一些主要市場參與者包括Allevi Inc.、Altis Biosystems、AxoSim、BiomimX Srl、Elveflow、Emulate Inc.、InSphero、MIMETAS、Nortis Inc.、TARA Biosystems Inc.、TissUse GmbH 等。
挑戰與機會:雖然技術複雜性和高成本帶來了挑戰,但日益向個人化醫療的轉變和向多器官模型的擴展帶來了重要的器官晶片市場機會。
加強藥物研發
器官晶片的市場潛力大大增加,因為它可以極大地促進藥物的開發和發現。與傳統的2D細胞培養物和動物模型相比,這些技術可以更精確地模擬人體器官的反應,因此有助於減少藥物測試和開發的時間。因此,這項創新提供了無與倫比的預測準確性,對於減少藥物發現過程中的持續時間、成本和失敗率至關重要。因此,製藥組織開始將器官晶片技術整合到其研發過程中,以縮小差距,從而推動個人化和精準醫療的進步以及更高的治療成功率。此外,這種轉變帶來了許多藥物快速獲得批准的前景,這部分彌補了那些在最後階段失敗的藥物的成本。
技術創新與合作
持續的技術進步是改變器官晶片產業的主要推動力之一。製造能夠同時複製多個器官系統功能的晶片是一種更完整的分析工具,涵蓋了臨床前測試的第一階段,並使臨床試驗更接近人群。正在進行的發明包括整合微流體、多維結構內的細胞 3D 列印以及自動化成像,使片上器官系統具有更好的功能和可擴展性。此外,生物技術公司、研究機構和技術專家之間的聯合已經形成了跨學科研究的策略環境,從而促進了該領域的快速進步。這些合作對於克服技術問題和改進應用以及促進有毒物質檢測、疾病建模和精準醫學等各個領域至關重要。例如,器官晶片(OOC) 技術透過提供更準確的預測模型徹底改變了傳統的體外 ADME 和毒性測試,從而促進藥物開發,預計每年成長率為 15%。 OOC 平台結合了多器官系統,增強了藥物動力學和藥效學研究,提供了對藥物分子的時間和劑量依賴性效應的深入了解。根據器官晶片市場收入,這些先進技術預計到 2025 年市場規模將達到 2.2 億美元,其精確的流量控制和快速的樣品處理優於傳統的 2D 培養,使其對於功效研究和毒性評估至關重要。
監管與道德轉變
關於動物在科學研究中的應用的倫理問題和更嚴格的法規也刺激了器官晶片產業的發展。世界各地的機構和部門逐漸認知到這些技術在提供比動物模型更相關的資料的價值。這正是美國食品藥物管理局的器官晶片計畫等項目所提倡的。因此,這種轉變與公眾和政府日益推動的動物友善調查技術是一致的。器官晶片技術不僅符合更高的監管標準,而且在倫理上也是有保證的,因為它們可以促進向更人性化和科學先進的研究技術的範式轉移。這種道德立場在晶片器官設備用於研究和開發的更廣泛批准中發揮著越來越重要的作用。
IMARC Group提供了每個細分市場的主要趨勢分析,以及 2024-2032 年全球、區域和國家層面的預測。我們的報告根據產品、類型、應用和最終用途對市場進行了分類。
產品
服務
該報告根據發行提供了詳細的市場細分和分析。這包括產品和服務。
肝
心
肺
腎
其他
龍業佔據產業最大佔有率
報告還提供了基於類型的詳細市場細分和分析。這包括肝臟、心臟、肺、腎臟等。報告稱,肺臟佔了最大的市場佔有率。
根據器官晶片市場趨勢,肺晶片由於其在呼吸系統研究和藥物發現中的高應用而得到最廣泛的應用。此技術適合對人體肺部的複雜結構和功能進行建模,為呼吸系統疾病、藥物反應評估、吸入物質毒性評估提供動態平台。它在加速開發針對不同肺部疾病(例如氣喘和慢性阻塞性肺病(COPD))的個人化療法過程中的作用確實得到了強調。晶片肺模型可以更可靠、更合乎道德地取代動物試驗,從而向當局保證藥物的功效和安全性,這是成功進入市場的先決條件。這使得藥物發現和生物技術成為該領域的領導角色,從而繼續並增加器官晶片的市場佔有率。
生理模型開發
藥物發現
毒理學研究
藥物發現代表了領先的細分市場
該報告根據應用程式提供了詳細的市場細分和分析。這包括生理模型開發、藥物發現和毒理學研究。根據該報告,藥物發現佔據了最大的部分。
根據晶片器官市場概述,藥物發現是藥物開發所有階段的最大部分。這是因為該部門擁有開發藥品流程的關鍵轉變方式。器官晶片系統可以以其他方式不可能的方式模擬人體器官在各種條件下的反應,使科學家能夠對潛在藥物進行早期篩選。電腦的這種能力成功地使我們能夠估計這些藥物將如何受到人體組織的影響,這反過來又朝著有效性和安全性測試過程的正確方向邁出了一步。因此,藥物發現時間大大縮短,臨床試驗成本和風險也降低。製藥公司對這些技術的廣泛利用表明該領域存在一個巨大的機會,可以使藥物搜尋更快,但不僅成本更低,而且符合更好的安全性和有效性監管要求。
製藥和生物技術公司
學術及研究機構
化妝品產業
其他
製藥和生物技術公司在市場上表現出明顯的主導地位
報告還提供了基於最終用途的詳細市場細分和分析。這包括製藥和生物技術公司、學術和研究機構、化妝品行業等。報告顯示,製藥和生物技術公司佔據了最大的市場。
製藥和生物技術公司佔據最大的市場佔有率。這種優點主要是由於微器官模型在這些產業的藥物發現和開發階段的使用增加所致。器官晶片公司利用技術複製人體功能及其反應,其水平高於使用動物實驗和2D細胞培養的傳統方法。提高匹配人體器官功能和在實驗室環境中相互作用的能力,可以在開發的早期階段更好地檢測藥物功效和毒性。它不僅提高了臨床試驗成功的前景,而且減少了新藥商業化過程中涉及的時間和成本。由於製藥和生物技術公司不斷尋找能夠加速研發過程的創新方法,器官晶片技術的利用率預計將不斷增加,因此使該細分市場成為市場上最大的細分市場,並創造了一個新的市場。器官晶片市場前景樂觀。
北美洲
美國
加拿大
亞太
中國
日本
印度
韓國
澳洲
印尼
其他
歐洲
德國
法國
英國
義大利
西班牙
俄羅斯
其他
拉丁美洲
巴西
墨西哥
其他
中東和非洲
北美市場領先,佔據最大的器官晶片市場佔有率
該報告還對所有主要區域市場進行了全面分析,其中包括北美(美國和加拿大);歐洲(德國、法國、英國、義大利、西班牙、俄羅斯等);亞太地區(中國、日本、印度、韓國、澳洲、印尼等);拉丁美洲(巴西、墨西哥等);以及中東和非洲。報告稱,北美是器官晶片最大的區域市場。
根據晶片器官市場報告,最大的市場是北美。這種優勢來自於強大的研究基礎設施、生物技術和製藥行業的良好資金支持,以及政府和私營部門對創新醫療保健解決方案的模範支持。地位隨著器官晶片技術需求的不斷成長,始終推動醫學現場工作前沿的研究機構。除此之外,該領域還培育了一個現有的監管框架,為藥物開發和個人化醫療(包括器官晶片)的尖端工具提供了很高的採用機會。這些經濟實體的主導地位推動其他參與者進行創新,這些技術的開發和部署有助於在全球市場中佔據區域主導地位。這種活躍且先進的獸醫系統提供了器官晶片市場成長模型,使這些模型可用於醫學研究和藥物測試。
The global organ-on-chip market size reached US$ 61.6 Million in 2023. Looking forward, IMARC Group expects the market to reach US$ 541.8 Million by 2032, exhibiting a growth rate (CAGR) of 26.5% during 2024-2032. The market is driven by its critical role in enhancing pharmaceutical R&D, stimulated by technological advancements, collaborative efforts, and increasing regulatory and ethical emphasis on reducing animal testing through more accurate and humane alternatives in medical research.
Major Market Drivers: The organ-on-chip market is expanding rapidly, driven by the need for more accurate and ethical research methods in pharmaceuticals and biotechnology.
Key Market Trends: Technological advancements such as 3D bioprinting and microfluidics are revolutionizing organ-on-chip models, increasing their accuracy and applicability.
Geographical Trends: North America leads the market, supported by robust research infrastructure and proactive regulatory policies; however, Europe and Asia-Pacific are quickly catching up due to rising investments in biotech.
Competitive Landscape: Some of the major market players in the organ-on-chip industry include Allevi Inc., Altis Biosystems, AxoSim, BiomimX S.r.l., Elveflow, Emulate Inc., InSphero, MIMETAS, Nortis Inc., TARA Biosystems Inc., TissUse GmbH., etc. among many others.
Challenges and Opportunities: While technological complexities and high costs pose challenges, the growing shift towards personalized medicine and the expansion into multi-organ models present significant organ-on-chip market opportunities.
Pharmaceutical Research and Development Enhancement
The organ-on-chip market potential is greatly increased because it can dramatically enhance drug development and discovery. These techniques provide a more precise simulation of how human organs respond compared to conventional 2D cell cultures, and animal models and hence they help to reduce the time taken in drug testing and development. This innovation, thus, offers unparalleled prediction accuracy, essential for decreasing the duration, cost, and failure rates during drug discovery. As a result, pharmaceutical organizations are starting to integrate organ-on-chip technologies into their R&D processes to narrow the gap, leading to the advancement of personalized and precise medicine and higher therapeutic success rates. Besides, this shift produces the prospect of many quick drug approvals which partly cover the cost of those that failed in the final stage.
Technological Innovations and Collaborations
Continuous technological advancements are one of the major stimuli that are transforming the organ-on-chip industry. The manufacturing of chips capable of replicating several organ systems' functionalities at the same time is a more complete analysis tool, covering the first stage of preclinical testing and bringing clinical trials closer to the population. The inventions being made include incorporating microfluidics, 3D printing of cells within multi-dimensional structures, and automated imaging which allows for better functionality and scalability of organ-on-chip systems. Furthermore, associations between biotech firms, research institutions, and technology specialists have formed a strategic environment for cross-disciplinary studies that, in turn, results in fast improvements in this field. These collaborations are vital to overcoming technical issues and improving applications, as well as promoting various sectors like toxic things testing, disease modeling, and precision medicine. For instance, Organ-on-chip (OOC) technology revolutionizes traditional in vitro ADME and toxicity tests by offering a more accurate predictive model, enhancing drug development with an estimated growth rate of 15% annually. Incorporating multi-organ systems, OOC platforms enhance pharmacokinetic and pharmacodynamic studies, providing insights into the time and dose-dependent effects of drug molecules. Based on organ-on chip market revenue, these advanced technology, projected to reach a market size of $220 million by 2025, outperforms conventional 2D cultures with its precise flow control and rapid sample processing, making it essential for efficacy studies and toxicity evaluations.
Regulatory and Ethical Shifts
Ethical issues and stricter regulations concerning the application of animals in scientific research are additionally stimulating the growth of the organ-on-chip industry. Agencies and departments all around the world are coming to recognize the value of these technologies in providing more relevant data than animal models. This is what is being promoted by endeavors such as the USFDA's Organ-on-Chip program. Therefore, this transition is consistent with the growing public and governmental push for animal-friendly investigation techniques. Organ-on-chip technologies, not only qualifying for higher regulatory standards, are also ethically warranted, since they can promote a paradigm shift towards more human and scientifically advanced research techniques. This ethical standpoint is getting an increasing role in wider approval for organ-on-chip devices to be used in research and development.
IMARC Group provides an analysis of the key trends in each segment of the market, along with forecasts at the global, regional, and country levels for 2024-2032. Our report has categorized the market based on offering, type, application, and end use.
Products
Services
The report has provided a detailed breakup and analysis of the market based on the offering. This includes products and services.
Liver
Heart
Lung
Kidney
Others
Lung holds the largest share of the industry
A detailed breakup and analysis of the market based on the type have also been provided in the report. This includes the liver, heart, lung, kidney, and others. According to the report, lung accounted for the largest market share.
According to the organ-on-chip market trend, the lung-on-chip is the most expanded due to its high application in respiratory studies and drug discovery. This technology is suitable for modeling the complex structure and function of the human lung to provide a dynamic platform for respiratory diseases, drug response evaluation, and inhaled substances toxicity assessment. Its role in the process of speeding up the development of personalized therapies for different lung diseases, such as asthma and chronic obstructive pulmonary disorder (COPD), is truly emphasized. Lung-on-chip model leads to a more reliable and ethical replacement of animal testing, hence the assurance of drug efficacy and safety to the authorities, which is a prerequisite for successful market entry. This shifts drug discovery and biotechnology to the leadership role in this area, continuing and increasing the organ-on-chip market share.
Physiological Model Development
Drug Discovery
Toxicology Research
Drug discovery represents the leading market segment
The report has provided a detailed breakup and analysis of the market based on the application. This includes physiological model development, drug discovery, and toxicology research. According to the report, drug discovery represented the largest segment.
As per the organ-on-chip market overview, drug discovery is the largest segment for all phases of drug development. This is because the segment has such a key transforming way of developing the processes of pharmaceutical products. Organ-on-chip systems can mimic human organs' responses under various conditions in a way that otherwise would be impossible, allowing scientists to do early screenings for a prospective drug. This ability of the computer successfully enables us to estimate how those drugs will be affected by the human tissues, which in turn creates a step in the right direction of the efficacy and safety test process. It therefore follows that the drug discovery time frame is greatly shortened, and the clinical trial costs and risk become lower. The broadening utilization of these technologies by a pharmaceutical company indicates a great opportunity in this area to make drug hunting faster but not only, less costly and in line with better regulatory requirements for safety and effectiveness.
Pharmaceutical and Biotechnology Companies
Academic and Research Institutes
Cosmetics Industry
Others
Pharmaceutical and biotechnology companies exhibit a clear dominance in the market
A detailed breakup and analysis of the market based on the end use have also been provided in the report. This includes pharmaceutical and biotechnology companies, academic and research institutes, cosmetics industry, and others. According to the report, pharmaceutical and biotechnology companies accounted for the largest market share.
The pharmaceutical and biotechnology companies account for the largest market share. This superiority is mainly caused by the increased usage of micro-organ models in the drug discovery and development phases of these industries. The organ-on-chip companies use technology to copy human body functions and its responses to a higher level than conventional methods which use animal experimenting and 2D cell cultures. Improved capacities to match human organ functions and interact in a laboratory setting provide better detection of drug efficacy and toxicity at an early stage of development. It not only improves the prospects of success in the clinical trials but also decreases the time and cost involved in the process of commercialization of a new drug. Being that pharmaceutical and biotechnology company are constantly in search of inventive ways that will accelerate the research and development process, the utilization of organ-on-chip technologies is anticipated to keep increasing, therefore making this segment the largest one in the market and creating a positive organ-on-chip market outlook.
North America
United States
Canada
Asia-Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
North America leads the market, accounting for the largest organ-on-chip market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, North America represents the largest regional market for organ-on-chip.
According to the organ-on-chip market report, the largest segment here is North America. This superiority comes from a strong research infrastructure, good funding of the biotechnology and pharmaceutical industry, and the exemplary support given to innovative healthcare solutions by the government and the private sector North American confident leadership in the market is further fortified by the existence of leading universities and research institutions that always drive the frontiers of the medical fieldwork with the Increasing organ-on-chip demand in technologies. Other than that, the area fosters an already existing regulatory framework that provides high adoption opportunities of cutting-edge tools for drug development and personalized medicine which include organ-on-chip. The dominance of these economic entities is what pushes other players to innovate the development and deployment of such technologies contribute to the regional prominence in the global market. This active and advanced veterinary system provides organ-on-chip market growth models which makes these models in use in medical research and pharmaceutical testing.
Allevi Inc.
Altis Biosystems
AxoSim
BiomimX S.r.l.
Elveflow
Emulate Inc.
InSphero
MIMETAS
Nortis Inc.
TARA Biosystems Inc.
TissUse GmbH
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)
Major players in the organ-on-chip industry keep improving and broadening their technological arsenals by different means, including research and development, cooperation, and mergers and acquisitions. According to organ-on-chip recent developments businesses aim to develop more specific and versatile organ-on-chip models capable of simulating human physiology more precisely for drug testing and disease modeling. The pragmatic cooperation is responsible for the quick product commercialization of new technologies in addition to broadening the microfluidic systems' application scope in personalized medicine, safety pharmacology, and complex biological research, which consequently fortifies their market positions. According to the organ-on-chip market forecast, strategic collaborations with pharmaceutical companies, academic institutions, and technology providers are creating a positive outlook for the market.
On March 7, 2023, Allevi, a pioneer in 3D bioprinting, adopted this transformative technology for its ability to accurately mimic human biological systems in animal-free research. Its expanding applications in drug discovery, regenerative and translational medicine, and preclinical research highlight the significant potential of this platform.
On January 23, 2024, CN Bio and Altis Biosystems partnered to create an advanced human Gut/Liver in vitro model for improved ADME studies, leveraging their organ-specific expertise for more accurate predictions. This next-generation Organ-on-a-Chip solution is available early through CN Bio's Contract Research Services.
On October 24, 2023, AxoSim, Inc., a leader in biomimetic human drug discovery platforms for neurological diseases, has completed its acquisition of microBrain(TM) assets from Vyant Bio's StemoniX subsidiary. This move enhances AxoSim's capabilities in advancing neurological research.