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市場調查報告書
商品編碼
1661108
2025 年至 2033 年生物製藥市場報告,按適應症(自體免疫疾病、腫瘤學、代謝紊亂等)、類別(重組蛋白、單株抗體、純化蛋白)和地區分類Biopharmaceutical Market Report by Indication (Autoimmune Diseases, Oncology, Metabolic Disorders, and Others), Class (Recombinant Proteins, Monoclonal Antibodies, Purified Proteins), and Region 2025-2033 |
2024IMARC Group全球生物製藥市場規模達到 3,262 億美元。慢性病發病率不斷上升、生物製藥的重大進步、政府支持和醫療支出的增加、個人化醫療和標靶治療、生物相似藥的擴張以及人工智慧和機器學習的利用率不斷提高等因素推動了市場的發展。
生物製藥,也稱為生物製劑,是一類源自生物來源的藥物。它們是利用細菌、酵母或哺乳動物細胞等生物體透過生物技術過程生產的。與化學合成的傳統小分子藥物不同,生物製藥是大型複雜分子,與體內的生物標靶表現出高度特異性的相互作用。與傳統藥物相比,它們具有多種優勢。它們的作用往往具有高度特異性,通常針對特定的受體或分子,從而提高療效並減少副作用。此外,生物製藥還有潛力治療以前難以用傳統藥物治療的疾病。
由於個人化醫療需求不斷增加,市場正在經歷顯著成長。此外,生物製藥在治療癌症、糖尿病、牛皮癬和類風濕性關節炎方面的應用越來越廣泛,這也是另一個主要的成長誘導因素。此外,大眾對生物製藥的有效性和可用性的認知不斷提高,這是另一個重要的成長因素。此外,對罕見疾病和孤兒藥的日益關注正在推動市場的成長。這些罕見疾病通常以患者人數少為特徵,存在著巨大的未滿足的醫療需求。除此之外,世界各國政府和監管機構都推出了激勵措施並簡化了監管流程,以鼓勵開發這些疾病的治療方法。此外,生物製藥公司正在投資研發針對罕見疾病的孤兒藥,從而解決關鍵醫療需求並為市場擴張創造機會。
個人化醫療需求不斷成長
個人化醫療已導致生物製藥市場向標靶治療和精準醫療方法的轉變。生物製藥公司越來越注重開發針對特定基因突變、生物標記或與疾病相關的分子路徑的治療方法。此外,個人化醫療推動了藥物基因組學的進步,該學科是研究個人基因組成如何影響其對藥物的反應。了解影響藥物代謝、功效和安全性的基因變異可以識別可能有不良反應風險的患者或更有可能對特定治療產生良好反應的患者。這些知識使生物製藥公司能夠針對個別患者制定針對性的治療方法和給藥方案,從而提高治療效果並降低不良事件的風險。
慢性病和生活方式相關疾病的盛行率不斷上升
慢性疾病,包括心血管疾病、糖尿病、癌症、呼吸系統疾病和自體免疫疾病,已成為全球主要的健康挑戰。這些疾病通常具有複雜的潛在機制,需要有針對性的個人化治療方法。單株抗體、重組蛋白和基因療法等生物製藥可提供精準的標靶和客製化的治療方案。這些療法可以針對與慢性疾病相關的特定分子路徑、受體或細胞,從而提高療效並減少副作用。此外,慢性病和生活方式相關疾病的負擔越來越重,人們的關注點從緩解症狀轉移到改善疾病和預防,這也推動了市場的成長。
生物技術的各種進步
生物技術大大加速了藥物發現和開發的進程。高通量篩選、組合化學和計算建模等先進技術能夠在更短的時間內識別和測試大量候選藥物。這提高了藥物研發的效率和速度,使生物製藥公司能夠更快地將新療法推向市場。此外,分析個別基因組成、識別疾病標記和了解分子路徑的能力使得針對特定患者群體的標靶治療方法的開發成為可能。基因組學、下一代定序和基因編輯技術等生物技術工具徹底改變了人們對疾病機制的理解,並推動了針對特定基因變異和分子標靶的治療方法的開發,從而推動了市場的發展。
The global biopharmaceutical market size reached USD 326.2 Billion in 2024. Looking forward, IMARC Group expects the market to reach USD 664.8 Billion by 2033, exhibiting a growth rate (CAGR) of 8.2% during 2025-2033. The market has been propelled by the increasing prevalence of chronic illnesses, significant advancements in biopharmaceutical, rising government support and healthcare expenditure, personalized medicine and targeted therapies, expansion of biosimilars, and increasing utilization of artificial intelligence and machine learning.
Biopharmaceuticals, also known as biologics, are a class of pharmaceutical drugs derived from biological sources. They are produced using living organisms, such as bacteria, yeast, or mammalian cells, through biotechnological processes. Unlike traditional small-molecule drugs, which are chemically synthesized, biopharmaceuticals are large, complex molecules that exhibit highly specific interactions with biological targets in the body. They offer several advantages over traditional pharmaceuticals. They tend to be highly specific in their action, often targeting specific receptors or molecules, resulting in increased efficacy and reduced side effects. Additionally, biopharmaceuticals have the potential to treat diseases that were previously challenging to address using conventional drugs.
The market is experiencing significant growth due to the escalating demand for personalized medicine. In addition, the increasing utilization of biopharmaceuticals to treat cancer, diabetes, psoriasis, and rheumatoid arthritis represents another major growth-inducing factor. Besides, the growing awareness among the masses regarding the effectiveness and availability of biopharmaceuticals represents another major growth-inducing factor. Moreover, the rising focus on rare diseases and orphan drugs is driving the growth of the market. These rare diseases, often characterized by small patient populations, present significant unmet medical needs. Other than this, governments and regulatory agencies worldwide have introduced incentives and streamlined regulatory processes to encourage the development of therapies for these conditions. Moreover, biopharmaceutical companies are investing in R&D to develop orphan drugs, which target rare diseases, thereby addressing critical medical needs and creating opportunities for market expansion.
The escalating demand for personalized medicine
Personalized medicine has led to a shift toward targeted therapies and precision medicine approaches in the biopharmaceutical market. Biopharmaceutical companies are increasingly focusing on the development of therapies that target specific genetic mutations, biomarkers, or molecular pathways associated with diseases. Moreover, personalized medicine has led to advancements in pharmacogenomics, which is the study of how an individual's genetic makeup influences their response to drugs. Understanding the genetic variations that impact drug metabolism, efficacy, and safety allows for the identification of patients who may be at risk of adverse reactions or those who are more likely to respond favorably to a specific treatment. This knowledge enables biopharmaceutical companies to develop targeted therapies and dosage regimens tailored to individual patients, enhancing treatment effectiveness and reducing the risk of adverse events.
The growing prevalence of chronic and lifestyle-related diseases
Chronic diseases, including cardiovascular disorders, diabetes, cancer, respiratory diseases, and autoimmune conditions, have become major global health challenges. These diseases often have complex underlying mechanisms, requiring targeted and personalized treatment approaches. Biopharmaceuticals, such as monoclonal antibodies, recombinant proteins, and gene therapies, offer precise targeting and tailored treatment options. These therapies can target specific molecular pathways, receptors, or cells associated with chronic diseases, resulting in enhanced efficacy and reduced side effects. Moreover, the increasing burden of chronic and lifestyle-related diseases has shifted the focus from symptomatic relief to disease modification and prevention, which is also propelling the market growth.
Various advancements in biotechnology
Biotechnology has greatly accelerated the drug discovery and development process. Advanced techniques, such as high-throughput screening, combinatorial chemistry, and computational modeling, enable the identification and testing of a large number of drug candidates in a shorter time frame. This has led to an increase in the efficiency and speed of drug discovery, allowing biopharmaceutical companies to bring new therapies to market more rapidly. Besides, the ability to analyze an individual's genetic makeup, identify disease markers, and understand molecular pathways has enabled the development of targeted therapies tailored to specific patient populations. Biotechnology tools, such as genomics, next-generation sequencing, and gene editing techniques, have revolutionized the understanding of disease mechanisms and enabled the development of therapies that address specific genetic variations and molecular targets, thus propelling the market.
Autoimmune diseases represent the leading segment
Autoimmune diseases are often chronic and complex conditions that require long-term management and treatment. These diseases can affect multiple organs and systems in the body, leading to a wide range of symptoms and complications. Biopharmaceutical therapies have shown promising results in managing and controlling autoimmune diseases, providing relief from symptoms, slowing disease progression, and improving quality of life for patients. Therapies, including monoclonal antibodies and other biologics, have emerged as a vital treatment option for autoimmune diseases. They target specific molecules, cells, or pathways involved in the autoimmune response, providing more precise and effective therapeutic interventions.
Monoclonal antibodies exhibit a clear dominance in the market
Monoclonal antibodies are highly specific in targeting disease-specific antigens or cells. They are designed to bind to a specific target with precision, minimizing off-target effects and reducing the risk of adverse reactions. This specificity contributes to their efficacy in treating various diseases, including autoimmune disorders, cancer, inflammatory conditions, and infectious diseases. They also have a wide range of therapeutic applications across different disease areas. They can be used as therapeutic agents on their own or in combination with other treatments. Monoclonal antibodies have been successful in neutralizing pathogens, blocking cell receptors, modulating immune responses, and delivering therapeutic payloads, making them versatile tools for disease management.
North America accounts for the majority of market share
The report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Latin America (Mexico, Brazil, and Argentina); Europe (Germany, France, Italy, Spain, the United Kingdom, Russia, and Turkey); and Asia Pacific (Japan, China, Australia, South Korea, India, and Indonesia). According to the report, North America was the largest market for biopharmaceuticals.
North America, particularly the United States, boasts a highly developed healthcare infrastructure, including robust research and development capabilities, advanced clinical facilities, and a strong regulatory framework. The region is home to renowned academic institutions, pharmaceutical companies, and research organizations that drive innovation in the biopharmaceutical industry. The presence of these institutions and infrastructure facilitates the development, manufacturing, and commercialization of biopharmaceutical products. The region has a well-established ecosystem that supports biopharmaceutical innovation, including government funding initiatives, research grants, venture capital investments, and collaborations between academia, industry, and research institutes.
The competitive landscape of the biopharmaceutical market is highly dynamic and competitive, with numerous global and regional players vying for market share. Nowadays, leading biopharmaceutical companies are heavily investing in R&D to discover and develop innovative therapies. They are conducting preclinical and clinical trials, and advance promising candidates through the regulatory approval process. These investments aim to expand their product pipelines, address unmet medical needs, and stay ahead of competitors in terms of therapeutic advancements. They are also forming strategic partnerships and collaborations with academic institutions, research organizations, and other industry players. These alliances enable them to access new technologies, scientific expertise, and complementary resources.
Pfizer and BioNTech developed and distributed their mRNA-based COVID-19 vaccine, Comirnaty (BNT162b2). The vaccine received emergency use authorizations and has been widely deployed globally, playing a crucial role in combating the COVID-19 pandemic.
Amgen Inc. recently received FDA approval for Lumakras (sotorasib), a targeted therapy for non-small cell lung cancer (NSCLC) with specific genetic mutations.
AbbVie Inc. has made significant advancements in immunology, particularly with its flagship product, Humira (adalimumab). Humira is one of the world's best-selling biologic drugs used to treat autoimmune conditions, including rheumatoid arthritis, psoriasis, and Crohn's disease.