市場調查報告書
商品編碼
1464888
去礦骨基質市場:按產品、型態、應用和最終用途 - 2024-2030 年全球預測Demineralized Bone Matrix Market by Product (Gel, Putty, Putty Combined with Cancellous Chips), Administration Mode (Implantation, Injection), Application, End-Use - Global Forecast 2024-2030 |
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脫礦骨基質市場規模預計到2023年為6.7114億美元,2024年達到7.1336億美元,預計到2030年將達到10.4637億美元,複合年成長率為6.54%。
去礦骨基質(DBM)是一種骨移植物,源自同種異體骨的膠原蛋白基質,經由酸萃取過程脫礦。這種脫礦過程暴露了骨生長因子,尤其是骨生成激素(BMP),使 DBM 具有骨誘導性並能夠促進新骨形成。 DBM 的使用不斷成長的主要因素包括其在骨骼修復和再生方面的有效性,其在各種整形外科、牙科和脊柱手術中作為移植物延長劑的作用,其減少自體移植物需求的潛力,從而包括最大限度地減少供體部位發病率。然而,DBM製劑之間骨誘導能力的差異、免疫抗原性反應的可能性以及某些DBM製劑的高成本對DBM製劑的採用提出了重大挑戰。為了解決這些限制,正在進行的研究和技術進步集中在提高 DBM 配方的一致性和骨誘導潛力。該策略包括開發將DBM與合成或天然生物材料結合的複合植入物,以改善結構和功能特性,以及先進的加工以在確保安全的同時保持生物活性。擴大新興地區的應用以及與下一代生技藥品的整合代表了 DBM 的動態成長路徑,並為研發和臨床應用打開了新的大門。
主要市場統計 | |
---|---|
基準年[2023] | 67114萬美元 |
預測年份 [2024] | 71336萬美元 |
預測年份 [2030] | 10.4637 億美元 |
複合年成長率(%) | 6.54% |
膩子與 DBM 產品的鬆質碎片的結合使用可以實現廣泛的骨骼修復。
DBM 凝膠是一種流動製劑,可輕鬆應用於需要精確骨移植的手術,例如脊椎融合手術和某些牙科應用。其延展性使其適合空間和精確度至關重要的微創手術。 DBM膩子在不需要結構支撐、需要最少干涉和精確塗抹的情況下是首選。 DBM 膩子是一種更具延展性的解決方案,可塗布手術部位並根據需要成型。由於其多功能性,它被廣泛用於各種骨骼修復手術,包括但不限於脊椎手術、骨折修復和關節重組。選擇它是因為其多功能性和易用性,適用於需要生長因子輸送和一定成型性的各種外科應用。含鬆質骨片的膩子是混合有鬆質骨片的DBM膩子,兼具骨誘導性和骨傳導性,使其成為修復大塊骨缺損和大規模重組手術的新選擇。此尖端適用於需要改善可成形性、穩定性和骨癒合特性的各種骨骼修復手術。
DBM 在應用整形外科手術的快速普及
脊椎融合手術利用脫礦骨基質 (DBM) 促進脊椎骨融合。此應用利用 DBM 的骨誘導特性來刺激人體的自然骨形成機制。透過協助融合過程,DBM 促進脊椎穩定,並為患有退化性椎間盤疾病、椎間滑脫、脊椎等的患者提供緩解。 DBM 在牙科手術中有著重要的應用,特別是與植入和牙周修復相關的骨移植。 DBM 充當支架,支持缺損部位新骨的生長,提高人工植牙的穩定性和成功率,並幫助因牙周病流失的骨再生。在整形外科,DBM 可用於治療骨缺損和骨折。 DBM 的骨傳導和骨誘導特性對於需要骨再生和修復的情況至關重要。 DBM 在關節重組置換術中的使用,特別是髖關節和膝關節關節重建,有助於假體關節組件與宿主骨的整合。 DBM 應用於合成骨組件周圍,以促進骨骼生長,從而植入並提高長期穩定性。在顱顎顏面手術中,DBM 用於修復創傷、先天性疾病或切除引起的骨缺損。它支持骨形成的能力對於這個複雜解剖區域的重組手術至關重要,從而獲得卓越的功能和美學效果。
區域洞察
在美洲,特別是在美國,由於先進的醫療基礎設施和骨骼相關疾病的高發病率,DBM 的使用受到嚴格監管但被廣泛接受。該地區的生產遵循嚴格的 FDA 法規,確保產品的安全性和有效性。各大公司都擁有強大的研發投資和廣泛的銷售網路的支持。亞太地區市場正在快速成長,但其特點是監管環境多樣化,以及因整形外科手術的興起而帶來的高需求。本土製造商不斷湧現,利用 DBM 產品和區域客製化的成本優勢。歐洲、中東和非洲市場根據國家的不同有不同的法規環境,是歐洲國家先進醫療保健系統與中東和非洲新興市場的均衡融合。該地區的特點是擁有大量全球 DBM 參與者和適應當地醫療保健需求和合規標準的當地子公司。這些公司正在將 DBM 添加到其全面的骨移植產品組合中,從而實現更廣泛的商業化。
FPNV定位矩陣
FPNV定位矩陣對於評估去礦骨基質市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可對脫礦骨基質市場供應商的現狀進行深入而詳細的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。這種詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,從而在市場上獲得競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4.競爭評估及資訊:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況、製造能力等進行綜合評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1.脫礦骨基質市場規模及預測為何?
2.在去礦骨基質市場的預測期內,有哪些產品、細分市場、應用和領域需要考慮投資?
3.脫礦骨基質市場的技術趨勢和法規結構是什麼?
4.脫礦骨基質市場主要供應商的市場佔有率為何?
5.進入脫礦骨基質市場合適的型態和策略手段是什麼?
[186 Pages Report] The Demineralized Bone Matrix Market size was estimated at USD 671.14 million in 2023 and expected to reach USD 713.36 million in 2024, at a CAGR 6.54% to reach USD 1,046.37 million by 2030.
Demineralized bone matrix (DBM) is a type of bone graft material obtained from the collagen matrix of allogeneic bone, which has had its mineral content removed through an acid extraction process. This demineralization process exposes the bone's growth factors, particularly bone morphogenetic proteins (BMPs), making DBM osteoinductive and capable of promoting new bone formation. The primary factors contributing to the expansion of DBM use include its efficacy in bone repair and regeneration, its role as a graft extender in various orthopedic, dental, and spinal surgeries, and its potential to reduce the need for autografts, thus minimizing donor site morbidity. However, the variability in osteoinductive potential between different DBM products, the potential for immunogenic reaction, and the high costs associated with some DBM preparations pose significant challenges to their adoption. To address these restraints, ongoing research, and technological advancements focus on enhancing the consistency and osteoinductive potential of DBM products. Strategies include the development of composite grafts that combine DBM with synthetic or natural biomaterials to improve structural and functional properties and the application of advanced processing and sterilization techniques to preserve biological activity while ensuring safety. Expanding applications in emerging regions and integration with next-generation biologics signify dynamic growth avenues for the DBM, opening new doors for research, development, and clinical application.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 671.14 million |
Estimated Year [2024] | USD 713.36 million |
Forecast Year [2030] | USD 1,046.37 million |
CAGR (%) | 6.54% |
Product: Adoption of putty combined with cancellous chips form of DBM for extensive bone repair situations
DBM gel is a fluid-like formulation that allows for easy application in surgeries requiring precise bone graft placement, such as spinal fusion and certain dental applications. Its malleability makes it well-suited for minimally invasive procedures where space and precision are paramount. They are preferred in scenarios requiring minimal intervention and precise application without structural support. DBM putty offers a more malleable solution that can be applied to the surgical site and shaped as needed. Its versatility makes it widely used in a variety of bone repair procedures, including, but not limited to, spinal surgeries, fracture repair, and joint reconstruction. They are chosen for their versatility and ease of use in a broad range of surgical applications where both the delivery of growth factors and some degree of moldability are required. Putty combined with cancellous chips form combines DBM putty with cancellous bone chips, offering both osteoinductive and osteoconductive properties, making it an ideal choice for procedures requiring a scaffold for new bone growth, such as large bone defect repair and major reconstructive surgeries. They are preferred in extensive bone repair procedures where a blend of moldability, stability, and enhanced bone healing properties are needed.
Application: Exponential adoption of DBM for orthopedic surgical procedures
In spinal fusion surgery, a demineralized bone matrix (DBM) is utilized to promote the fusion of vertebrae. This application leverages the osteoinductive properties of DBM, which stimulate the body's natural bone-forming mechanisms. By aiding in the fusion process, DBM facilitates the stabilization of the spine, offering relief to patients with conditions such as degenerative disc disease, spondylolisthesis, and scoliosis. DBM finds significant applications in dental surgery, particularly in bone grafting procedures associated with dental implants and periodontal disease repair. It acts as a scaffold, supporting new bone growth in areas of deficiency, thus enhancing the stability and success rate of dental implants and aiding in the regeneration of bone lost to periodontal disease. Orthopedic surgery benefits from DBM in the treatment of bone defects and fractures. DBM's osteoconductive and osteoinductive characteristics are vital in scenarios where bone regeneration and repair are required. The use of DBM in joint reconstruction surgeries, particularly in hip and knee replacements, enhances the integration of the prosthetic components with the host bone. It is applied around the prosthetic components to promote bone ingrowth, thereby securing the implant and improving its long-term stability. In craniomaxillofacial procedures, DBM is used to repair bone defects resulting from trauma, congenital conditions, or resections. Its ability to support bone formation makes it an integral part of reconstructive surgeries in this complex anatomical region, contributing to both functional and aesthetic outcomes.
Regional Insights
In the Americas, particularly the United States, the use of DBM is highly regulated but widely accepted, driven by an advanced healthcare infrastructure and a high incidence of bone-related disorders. Production in this region is characterized by stringent FDA regulations, ensuring product safety and efficacy. Major companies are backed by robust R&D investments and expansive distribution networks. The APAC market, while rapidly growing, presents a contrast with a diverse regulatory landscape and a high need stemming from increasing orthopedic surgeries. Local manufacturers are emerging, leveraging cost advantages and regional customization of DBM products. The EMEA market, with its diverse regulatory environment across countries, shows a balanced blend of advanced healthcare systems in European countries and emerging markets in the Middle East and Africa. The region is marked by a strong presence of both global DBM players and local entities adapting to regional healthcare needs and compliance standards. They are working on including DBM with their comprehensive bone graft portfolio, enabling its wider commercialization.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Demineralized Bone Matrix Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Demineralized Bone Matrix Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Demineralized Bone Matrix Market, highlighting leading vendors and their innovative profiles. These include Advanced Biotech Products P Ltd, AlloSource, Arthrex, Inc., Bioventus LLC, Cerapedics.Inc., Curasan AG, Exactech, Inc., Geistlich Pharma AG, Globus Medical, HansBioMed., Institut Straumann AG, Integra LifeSciences Holdings Corporation, Johnson & Johnson Services, Inc., KLS Martin SE & Co. KG, Kuros Biosciences Ltd., Medtronic PLC, NovaBone by Halma PLC, Orthofix Medical Inc., Osteogenics Biomedical, RTI Surgical Holdings, Inc., SpineWave, Inc., Stryker Corporation, Synerheal, XTANT Medical, and Zimmer Biomet.
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Demineralized Bone Matrix Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Demineralized Bone Matrix Market?
3. What are the technology trends and regulatory frameworks in the Demineralized Bone Matrix Market?
4. What is the market share of the leading vendors in the Demineralized Bone Matrix Market?
5. Which modes and strategic moves are suitable for entering the Demineralized Bone Matrix Market?
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