市場調查報告書
商品編碼
1470776
局部止血劑市場:按產品、配方、應用和最終用途 - 全球預測 2024-2030Topical Hemostat Market by Product, Formulation, Application, End-Use - Global Forecast 2024-2030 |
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預計2023年外用止血劑市場規模為21.2億美元,預計2024年將達22.6億美元,2030年將達33.6億美元,複合年成長率為6.80%。
外用止血劑是指用於促進止血的產品。當直接塗布傷口或手術部位時,它可以防止過度出血並促進血塊形成。局部止血劑用於各種醫療環境,從急診和外科手術到慢性傷口處理。外用止血劑含有促進人體自然凝血過程或提供物理屏障以幫助抑制血液的活性物質。由於人口老化和慢性病增加,全球手術數量增加推動了該市場的發展。然而,先進止血材料的高成本以及與使用某些止血材料相關的潛在併發症可能會限制其應用並限制其可用性。然而,能夠模仿自然止血的合成和生物活性材料的開拓以及新興市場止血劑開發中奈米技術的使用預計將為市場提供利潤豐厚的機會。
主要市場統計 | |
---|---|
基準年[2023] | 21.2億美元 |
預測年份 [2024] | 22.6億美元 |
預測年份 [2030] | 33.6億美元 |
複合年成長率(%) | 6.80% |
由於預防產品感染疾病等其他好處,外用止血劑的合併使用正在迅速增加。
基於膠原蛋白的局部止血劑源自於動物膠原蛋白,並透過提供促進凝塊形成的基質來促進止血。膠原蛋白吸引並活化血小板,促進自然凝血連鎖。這些產品型態多種形式,包括海綿、粉末和薄膜,用於各種手術環境中控制出血。組合局部止血劑結合了多種止血劑或機制以增強其有效性。它通常將膠原蛋白或明膠等物理基質與凝血酶和抗生素等促凝血物質結合以預防感染。此類多效產品同時提供控制出血和控制感染等其他益處,使其適合在手術領域更困難的出血情況下使用。明膠局部止血劑由豬或牛來源的明膠組成,通常呈現顆粒、發泡體或壓縮海綿形式。這些止血材料提供了吸收血液並將凝血因子濃縮在出血部位的物理基質。明膠止血劑由於其有效性和易於使用而常用於手術和緊急情況。氧化再生纖維素基止血材料(外用止血劑)是透過對植物來源的纖維素進行化學處理而製成的,以提高其止血性能。這些產品提供凝血基質,降低傷口周圍的 pH 值,並有助於止血過程。基於凝血酶的局部止血劑含有凝血酶,這是一種將纖維蛋白原轉化為纖維蛋白的酶,誘導血塊形成。這些止血劑由人類、牛或重組凝血酶製成,通常與其他材料(例如明膠或膠原蛋白墊片)結合使用。當手動壓力不足或不切實際時,這種類型的止血劑對於控制出血特別有用。
配方:基質和凝膠止血材料擴大使用,因為它們能夠適應不規則的傷口表面。
基質和凝膠止血劑是生物可吸收劑,其工作原理是提供支撐穩定血栓形成的物理支架。它們通常含有天然或合成物質,如膠原蛋白、明膠和纖維素。這些物質可與凝血酶和其他活性凝血劑結合,增強止血效果。粉狀止血劑由顆粒狀或絨毛狀材料組成,黏附在傷口部位並透過脫水機制和凝血因子濃縮來幫助凝血。通常使用高嶺土、沸石和其他礦物質等活性成分。它們特別有利,因為它們易於應用於出血表面,可用於微創手術,並且可以使用施用器或氣腹進行應用。片狀止血器和墊片止血器通常是止血材料的扁平結構,設計用於直接放置在出血組織表面上。常用的材料有氧化再生纖維素(ORC)、聚乙二醇(PEG)聚合物和膠原蛋白等。這些材料通常是優選的,因為它們易於處理,可以切割成所需的形狀,並且適合提供促進凝塊形成的機械屏障。海綿止血劑由明膠或膠原蛋白等可吸收材料製成,具有多孔結構,可為凝塊形成提供機械支撐,並為血小板黏附和聚集提供基質。這些止血材料常用於各種外科手術,可應用於滲出表面或填充難以控制出血的空腔。
應用局部止血劑在心血管手術的重要用途
在心血管手術中,局部止血劑廣泛用於控制血管吻合、移植部位和心臟組織的出血。它對於高風險患者的促進止血起著至關重要的作用,並且在準確的止血管理對於防止出血過多、血腫形成以及因出血而再次手術等併發症至關重要的情況下發揮著至關重要的作用。普通手術涉及多種手術,其中使用局部止血劑來控制手術部位的出血。這些藥物可控制手術期間的出血,無論是開放性手術或腹腔鏡手術。它可用於多種組織和器官,透過使手術野更加乾燥,有望提高手術效果並縮短手術時間。肝臟和脾臟的撕裂通常會導致大量出血,因為這些器官是血管性的。在這種情況下,局部止血劑對於控制出血至關重要,可以快速止血以穩定患者的病情。整形外科手術,尤其是涉及關節關節重建和截骨術的手術,可能會導致大量出血。局部止血劑用於止血骨表面和軟組織,可以減少術中出血,最大限度地減少術後瘀傷和血腫,並縮短癒合時間。在重組手術中,仔細止血對於確保移植物的活力和美觀效果至關重要。局部止血劑可控制供體和受體部位的出血,最大限度地減少失血並降低術後併發症的風險,例如影響重組成功的血清腫和血腫形成。
最終用途:醫院局部止血劑使用的演變
外用止血劑用於醫院的各個科室,例如急診室和手術室,特別是在心血管外科、整形外科和器官移植等高出血風險的手術中。在醫院中,止血材料用於各種手術,從複雜手術到常規手術,因此通常需要穩定的止血材料供應,這使其成為製造商的重要市場。療養院使用的局部止血劑主要用於需要小型手術或侵入性手術的老年族群。儘管療養院的使用量遠低於醫院,但需要各種止血劑來適應因老齡化相關併發症而出血風險增加的患者。門診手術中心是進行不需要住院的手術的專業設施。這些中心強調手術病例的效率和快速週轉,通常需要速效局部止血劑來提高患者吞吐量並縮短手術時間。整容手術、微創手術等擇期手術經常在這些中心進行,導致對止血材料的需求穩定。
區域洞察
在醫療基礎設施、高人均醫療成本以及對先進外科手術的關注的支持下,美洲局部止血劑市場呈現強勁成長。此外,外科手術的普及和先進傷口管理推動的消費者需求正在推動市場成長,因為人們對局部止血劑的有效性的認知很高,並且醫療保健提供者準備採用新技術。最近的投資主要集中在美洲開發高度生物相容性和生物分解性的止血材料。歐盟 (EU) 擁有完善的醫療保健系統,強調病人安全和高標準護理,這推動了歐洲對局部止血劑的需求。大型製藥公司的存在和對研究的大量投資為市場成長創造了有利的環境。同時,由於消費者對先進醫療產品的認知以及與醫療基礎設施和私人醫療保健行業的開拓相關的需求不斷成長,中東和非洲的市場正在擴大。這些地區的投資和舉措著重於建立醫療保健服務的能力,包括採用有效的手術輔助器具,例如外用止血劑。由於亞太地區人口眾多、經濟不斷成長以及對醫療保健創新的投資,亞太地區代表了一個多元化且快速擴張的局部止血劑市場。此外,政府的支持和對醫療保健技術自給自足的關注正在推動市場成長,從而帶動本地製造和創新的激增。亞太地區的最新專利反映出,考慮到經濟和醫療保健服務的限制,開發適合當地市場的創新止血劑的措施。
FPNV定位矩陣
FPNV定位矩陣對於評估外用止血劑市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可以對局部止血劑市場供應商的現狀進行深入而深入的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,從而在市場上獲得競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4.競爭力評估及資訊:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況、製造能力等進行全面評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1.局部止血劑市場規模及預測是多少?
2.在外用止血劑市場的預測期間內,有哪些產品、細分市場、應用和領域需要考慮投資?
3.外用止血劑市場的技術趨勢和法規結構是什麼?
4.局部止血劑市場主要廠商的市場佔有率是多少?
5. 進入局部止血劑市場的合適型態和策略手段是什麼?
[184 Pages Report] The Topical Hemostat Market size was estimated at USD 2.12 billion in 2023 and expected to reach USD 2.26 billion in 2024, at a CAGR 6.80% to reach USD 3.36 billion by 2030.
A topical hemostat refers to products used to promote hemostasis, a process of stopping bleeding. It is applied directly to a wound or surgical site to prevent excessive blood loss and to encourage clot formation. Topical hemostats are used in various medical situations, from emergency settings and surgical procedures to managing chronic wounds. Topical hemostats contain active substances that accelerate the body's natural clotting process or provide a physical barrier to assist with blood containment. A global rise in surgeries due to an aging population and the elevating incidences of chronic diseases is driving the market. However, the high cost of advanced hemostats and potential complications associated with using certain hemostatic agents can restrict their application and limit their accessibility. Nevertheless, the development of synthetic and bioactive materials that can mimic natural hemostasis and the utilization of nanotechnology in developing advanced hemostatic agents are expected to create lucrative opportunities for the topical hemostat market.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 2.12 billion |
Estimated Year [2024] | USD 2.26 billion |
Forecast Year [2030] | USD 3.36 billion |
CAGR (%) | 6.80% |
Product: Burgeoning adoption of combination topical hemostats owing to the additional benefits such as infection reduction
Collagen-based topical hemostats are derived from animal collagen, which promotes hemostasis by providing a matrix that facilitates clot formation. Collagen attracts and activates platelets, enhancing the natural coagulation cascade. These products, such as sponges, powders, or films, can come in various forms and are used in different surgical scenarios to control bleeding. Combination topical hemostats incorporate multiple hemostatic agents or mechanisms to enhance their efficacy. They often combine a physical matrix, such as collagen or gelatin, with a procoagulant substance like thrombin or an antibiotic agent to prevent infection. These multi-action products provide simultaneous bleeding control and additional benefits such as infection reduction and are suitable for use in more challenging bleeding situations in surgical settings. Gelatin-based topical hemostats consist of porcine or bovine-derived gelatin and often come as granules, foams, or compressed sponges. These hemostats provide a physical matrix that can absorb blood and concentrate clotting factors at the bleeding site. Gelatin-based hemostats are commonly used in surgical and emergency settings due to their efficacy and ease of application. Oxidized regenerated cellulose-based topical hemostats are made from plant-derived cellulose that is chemically treated to improve its hemostatic properties. These products provide a matrix for clotting and lowering the pH around the wound, which assists in the hemostasis process. Thrombin-based topical hemostats contain thrombin, an enzyme that converts fibrinogen to fibrin, thereby inducing clot formation. These hemostats can be made from human, bovine, or recombinant thrombin and are often applied in conjunction with other materials, including gelatin or collagen pads. This category of hemostatic agent is particularly useful in controlling bleeding when the application of manual pressure is insufficient or impractical.
Formulation: Proliferating utilization of matrix and gel hemostats owing to their ability to conform to irregular wound surfaces
Matrix and gel hemostats are bioresorbable agents that work on the principle of providing a physical scaffold to assist in the formation of a stable blood clot. They often contain natural or synthetic substances such as collagen, gelatin, or cellulose. These materials can be combined with thrombin or other active clotting agents to enhance hemostasis. Powder hemostats comprise granular or fluffy materials that adhere to the wound site and assist in clotting through dehydration mechanisms and concentration of clotting factors. Active ingredients such as kaolin, zeolite, or other mineral substances are commonly used. They are particularly advantageous for their ease of application on bleeding surfaces, their usefulness in minimally invasive procedures, and their ability to be applied using applicators or insufflators. Sheet and pad hemostats are usually flat configurations of hemostatic materials designed to be placed directly onto bleeding tissue surfaces. Materials such as oxidized regenerated cellulose (ORC), polyethylene glycol (PEG) polymers, and collagen are commonly used in these formats. They are often preferred for their ease of handling, ability to cut to required shapes, and suitability for providing a mechanical barrier that facilitates clot formation. Sponge hemostats are made from absorbable materials such as gelatin or collagen, which have a porous structure that provides mechanical support for clot formation and a matrix for platelet adhesion and aggregation. These hemostats are commonly used in various surgical procedures and can be applied to oozing surfaces or fill cavities where controlling bleeding is challenging.
Application: Significant usage of topical hemostats in cardiovascular surgery
In cardiovascular surgery, topical hemostats are extensively used to manage bleeding from vascular anastomoses, graft sites, and heart tissues. They are pivotal in promoting hemostasis in high-risk patients or scenarios where precise hemostatic control is critical to prevent excessive blood loss and potential complications such as hematoma formation or reoperation due to bleeding. General surgery involves various procedures where topical hemostats are applied to control bleeding from the surgical site. Whether in open or laparoscopic procedures, these agents reduce intraoperative bleeding. They can be used on various tissues and organs to ensure a drier operative field, which may improve surgical outcomes and shorten operative times. Liver and spleen lacerations often result in significant bleeding due to the vascular nature of these organs. Topical hemostats are crucial in managing bleeding in such cases, providing rapid hemostasis for patient stability. Orthopedic surgeries, particularly those involving joint replacements or bone cutting, can cause significant bleeding. Topical hemostats are used to provide hemostasis at bone surfaces and soft tissue, reducing intraoperative bleeding and potentially minimizing postoperative bruising, hematoma, and improving healing time. In reconstructive surgery, achieving meticulous hemostasis is critical to ensure graft viability and aesthetic outcomes. Topical hemostats are utilized to manage bleeding from both donor and recipient sites, minimizing blood loss and mitigating the risk of postoperative complications such as seroma or hematoma formation, which could compromise the success of the reconstruction.
End-Use: Evolving utilization of topical hemostats in hospitals
Topical hemostats are utilized across various departments of hospitals, such as emergency wards and operating theatres, especially in surgeries involving high bleeding risks, such as cardiovascular, orthopedic, and organ transplantations. Hospitals often require a consistent supply of hemostats due to their broad service in complex and routine surgeries, making them a critical market for manufacturers. Nursing homes adopt topical hemostats, focusing mainly on the geriatric population that may require minor surgical or invasive procedures. Although the volume of use in nursing homes is significantly lower than in hospitals, they still need an array of hemostatic agents to cater to patients who may have heightened bleeding risks due to age-related comorbid conditions. Ambulatory surgical centers, or outpatient surgical centers, are specialized facilities where surgeries that do not require hospital admission. These centers value efficiency and the rapid turnover of surgical cases, often looking for fast-acting topical hemostats to enhance patient throughput and reduce procedure times. The frequency of elective surgeries, such as cosmetic and minimally invasive procedures, at these centers contributes to a steady demand for hemostatic products.
Regional Insights
The Americas exhibit robust growth in the topical hemostat market supported by healthcare infrastructure, high per capita healthcare expenditure, and a focus on advanced surgical procedures. Furthermore, the consumer need, due to the prevalence of surgical procedures and advanced wound management practices with high awareness of the effectiveness of topical hemostats and the readiness of healthcare providers to adopt new technologies, bolster the market growth. Recent investments are primarily channeled toward developing advanced biocompatible and biodegradable hemostats in the Americas. The European Union boasts a sophisticated healthcare system with a strong emphasis on patient safety and high standards of care, which drives the demand for topical hemostats in Europe. The presence of major pharmaceutical companies, coupled with significant investments in research, creates a favorable environment for market growth. On the other hand, in the Middle East and Africa, the market is growing owing to consumers' awareness of advanced medical products and rising demand linked to the development of healthcare infrastructure and the private healthcare sector. Investments and initiatives in these regions focus on capacity building in healthcare services, including adopting effective surgical aids such as topical hemostats. The Asia Pacific region presents a diverse and rapidly expanding topical hemostat market owing to its sizeable populations, growing economies, and investment in healthcare innovation. Furthermore, government backing and a focus on self-sufficiency in healthcare technologies have spurred market growth, leading to a surge in local manufacturing and innovation. The latest patents in the APAC region reflect a drive towards developing innovative hemostatic agents suitable for the local market, considering the economic and healthcare delivery constraints.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Topical Hemostat Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Topical Hemostat Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Topical Hemostat Market, highlighting leading vendors and their innovative profiles. These include Aegis Lifesciences Private Limited, Axio Biosolutions Pvt Ltd, B.Braun Melsungen AG, Baxter International, Inc., Becton, Dickinson and Company, Betatech Medical, BioCer Entwicklungs-GmbH, Bristol-Myers Squibb Company, Dilon Technologies Inc, GELITA MEDICAL GmbH, Hemostasis, LLC, Integra LifeSciences Corporation, Johnson & Johnson Services, Inc., Marine Polymer Technologies, Inc., Medline Industries, LP, Medtrade Products Ltd, Medtronic PLC, Meril Life Sciences Pvt. Ltd, Pfizer Inc., Southmedic Inc., Stryker Corporation, SYMATESE SAS, Takeda Pharmaceutical Company Limited, Teleflex Incorporated, and Zeria Pharmaceutical Co., Ltd..
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Topical Hemostat Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Topical Hemostat Market?
3. What are the technology trends and regulatory frameworks in the Topical Hemostat Market?
4. What is the market share of the leading vendors in the Topical Hemostat Market?
5. Which modes and strategic moves are suitable for entering the Topical Hemostat Market?