市場調查報告書
商品編碼
1471193
單株抗體治療市場:按來源、最終用戶、應用分類 - 2024-2030 年全球預測Monoclonal Antibody Therapeutics Market by Source (Chimeric, Human, Humanized), End User (Hospitals, Private Clinics, Research Institute), Application - Global Forecast 2024-2030 |
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預計2023年單株抗體治療市場規模為1,533.5億美元,預估2024年將達1,698.7億美元,2030年將達3,253.7億美元,複合年成長率為11.34%。
單株抗體 (mAb) 療法涉及使用實驗室設計的抗體來模擬免疫系統靶向和消滅病毒和細菌等有害病原體的能力。單株抗體旨在針對和中和特定病原體,對治療多種疾病非常有效,包括癌症、自體免疫疾病、感染疾病和循環系統疾病。全球範圍內慢性疾病(例如癌症和自體免疫疾病)的發生率不斷增加,由於其治療的特異性和有效性,顯著增加了對單株抗體療法的需求。眾多針對生物製藥研究和開發的政府計劃和資助機會正在對單株抗體治療市場產生積極影響。然而,從小規模實驗室生產轉向大規模商業生產面臨挑戰,例如維持產品品質和一致性。單株抗體可以引發患者的免疫反應,而其他效能限制則會影響療效和安全性。主要企業正在透過將單株抗體與強大的細胞毒性藥物結合來增強單株抗體的治療效果,以改善癌症和其他嚴重的治療。生物加工方面的創新,例如連續製造和一次性技術,可以解決當前的生產和可擴展性挑戰,降低成本並提高可及性。此外,向個人化醫療的轉變以及將抗體藥物複合體納入各種疾病的治療中,為單株抗體療法創造了新的可能性。
主要市場統計 | |
---|---|
基準年[2023] | 1533.5億美元 |
預測年份 [2024] | 1698.7億美元 |
預測年份 [2030] | 3253.7億美元 |
複合年成長率(%) | 11.34% |
來源 人類單株抗體由於其低免疫抗原性而變得普及
嵌合體單株抗體是人工抗體,其中大部分抗體分子源自人類,只有一小部分源自非人類物種(通常是小鼠)。與小鼠源性單株抗體相比,這種組合降低了免疫抗原性並維持了所需的抗原特異性。人類單株抗體由人類基因和蛋白質製成。這種方法顯著降低了免疫抗原性反應的可能性,並使這些抗體與人體免疫系統更相容。人類單株抗體是使用噬菌體展示和基因轉殖小鼠等技術生產的,這些技術可產生人類抗體,在治療應用中提供高特異性和安全性。人源化單株抗體是將非人類抗體的互補決定區(特異性抗原結合部分)移植到人類抗體的骨架上而產生的。此方法可顯著降低免疫抗原性,同時保持抗體標靶的特異性。人源化抗體在保留非人類抗體所需的活性和最大限度地減少對它們的潛在免疫反應之間取得了平衡。
最終使用者:在醫院中擴大採用,準確的診斷監測和管理通常涉及靜脈注射
單株抗體療法在醫院用於管理和治療癌症、自體免疫疾病和感染疾病等慢性疾病。這種用途源於特異性針對患病細胞和病原體而不影響周圍健康組織的能力,從而減少副作用並加速患者康復。在私人診所,這些治療藥物主要用於治療需要個人化治療通訊協定的疾病患者,例如類風濕性關節炎、乾癬和其他自體免疫疾病。單株抗體的高精度可以實現量身定做的治療,提高治療效果並改善患者的治療結果。研究機構正利用單株抗體療法作為推進醫學科學的重要工具。研究機構對於開發新治療方法和闡明疾病機制至關重要。這些研究機構專注於創新和改進單株抗體技術,為各個醫學領域的下一代治療方法鋪路。
區域洞察
以美國和加拿大為中心的美洲地區擁有高度發展和發展的研發環境,擁有先進的研究設施、龐大的醫療成本以及保護創新的強大專利環境。美國消費者的需求很大程度上是由對癌症、自體免疫疾病和其他慢性病的有效、有針對性的治療的需求所驅動的。美國食品藥物管理局(FDA)積極核准單株抗體療法,進一步推動市場成長。最近的投資主要集中在癌症研究上,生技公司和政府為創新治療方法提供資金。歐盟(EU)國家是全球單株抗體治療市場的主要貢獻者。優質的醫療保健系統、廣泛的研究網路和有利的政府政策支持該地區的市場成長。歐盟消費者需求的特徵是越來越偏好個人化醫療和創新治療選擇。歐洲藥品管理局 (EMA) 促進新治療方法的核准,最近的重點是癌症和免疫學。關於單株抗體的性能、安全性、功效和生產的嚴格規定為治療學的進步提供了標準化框架。由於政府在生物技術和醫療保健方面的大量投資,亞太地區的單株抗體治療市場正在迅速擴大。中國政府對生物醫學和醫療改革的支持正在為研究和引進新治療方法創造機會。日本是亞洲領先的醫療保健市場之一,消費者對創新單株抗體療法(尤其是與年齡相關的疾病)表現出強勁的需求。印度的景觀正在崛起,醫療保健意識的提高和醫療服務的改善推動了成長。為了有效滿足消費者的需求,本地生產和降低處理成本越來越受到重視。
FPNV定位矩陣
FPNV 定位矩陣對於評估單株抗體治療市場至關重要。我們檢視與業務策略和產品滿意度相關的關鍵指標,以對供應商進行全面評估。這種深入的分析使用戶能夠根據自己的要求做出明智的決策。根據評估,供應商被分為四個成功程度不同的像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一種綜合工具,可以對單株抗體治療市場供應商的現狀進行深入而深入的研究。全面比較和分析供應商在整體收益、基本客群和其他關鍵指標方面的貢獻,以便更好地了解公司的績效及其在爭奪市場佔有率時面臨的挑戰。此外,該分析還提供了對該行業競爭特徵的寶貴見解,包括在研究基準年觀察到的累積、分散主導地位和合併特徵等因素。詳細程度的提高使供應商能夠做出更明智的決策並制定有效的策略,從而在市場上獲得競爭優勢。
1. 市場滲透率:提供有關主要企業所服務的市場的全面資訊。
2. 市場開拓:我們深入研究利潤豐厚的新興市場,並分析其在成熟細分市場的滲透率。
3. 市場多元化:提供有關新產品發布、開拓地區、最新發展和投資的詳細資訊。
4. 競爭評估和情報:對主要企業的市場佔有率、策略、產品、認證、監管狀況、專利狀況和製造能力進行全面評估。
5. 產品開發與創新:提供對未來技術、研發活動和突破性產品開發的見解。
1.單株抗體治療市場的市場規模與預測是多少?
2.單株抗體治療市場預測期間需要考慮投資的產品、細分市場、應用和領域有哪些?
3.單株抗體治療市場的技術趨勢和法規結構是什麼?
4.單株抗體治療市場主要廠商的市場佔有率是多少?
5.進入單株抗體治療市場的合適型態和策略性手段是什麼?
[187 Pages Report] The Monoclonal Antibody Therapeutics Market size was estimated at USD 153.35 billion in 2023 and expected to reach USD 169.87 billion in 2024, at a CAGR 11.34% to reach USD 325.37 billion by 2030.
Monoclonal antibody (mAb) therapeutics involves the use of antibodies engineered in the laboratory to mimic the immune system's ability to target and destroy harmful pathogens such as viruses and bacteria. Monoclonal antibodies are designed to target and neutralize specific pathogens, making them highly effective in the treatment of a variety of diseases, including cancer, autoimmune diseases, infectious diseases, and cardiovascular disorders. The growing incidence of chronic diseases worldwide, such as cancer and autoimmune disorders, significantly drives the need for monoclonal antibody therapeutics due to their specificity and efficacy in treatment. Numerous government programs and funding opportunities for research and development in biopharmaceuticals have positively impacted the monoclonal antibody therapeutics market. However, transitioning from small-scale laboratory production to large-scale commercial production presents challenges, including maintaining product quality and consistency. The potential of monoclonal antibodies to trigger immune responses in patients and other performance limitations affects efficacy and safety profiles. Key players are enhancing the therapeutic efficacy of monoclonal antibodies by conjugating them with potent cytotoxic to improve the treatment of cancers and other severe diseases. Innovations in bioprocessing, such as continuous manufacturing and single-use technologies, can address current production and scalability challenges, reducing costs and improving accessibility. Moreover, the shift towards personalized medicine and the incorporation of antibody-drug conjugates for the treatment of various diseases has further created new avenues of opportunities for monoclonal antibody therapeutics.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 153.35 billion |
Estimated Year [2024] | USD 169.87 billion |
Forecast Year [2030] | USD 325.37 billion |
CAGR (%) | 11.34% |
Source: Rising prevalence of human monoclonal antibodies due to their lower immunogenicity
Chimeric monoclonal antibodies are engineered antibodies where the majority of the antibody molecule is derived from human sources, with a minor portion being sourced from non-human species, typically mice. This combination reduces immunogenicity compared to fully murine monoclonal antibodies while retaining the desired antigen specificity. Human monoclonal antibodies are sourced from human genes and proteins. This approach significantly decreases the potential for immunogenic reactions, making these antibodies more compatible with human immune systems. They are produced using techniques such as phage display or transgenic mice engineered to produce human antibodies, offering high specificity and safety in therapeutic applications. Humanized monoclonal antibodies are created by grafting the non-human antibody's complementarity-determining regions (the specific parts that bind to the antigen) onto a human antibody framework. This method maintains the antibody's specificity towards its target while significantly reducing its immunogenicity. Humanized antibodies balance retaining the desired activity of non-human antibodies and minimizing potential immune responses against them.
End User: Increasing adoption in hospitals necessity for precise diagnostic oversight and administration typically involving intravenous infusion
In hospitals, monoclonal antibody therapeutics are used to manage and treat chronic illnesses such as cancer, autoimmune diseases, and infectious diseases. This utilization stems from their ability to specifically target diseased cells or pathogens without affecting surrounding healthy tissues, thus limiting side effects and promoting rapid patient recovery. In private clinics, these therapeutics find application primarily in treating patients with conditions that require personalized care protocols, including rheumatoid arthritis, psoriasis, and other autoimmune disorders. The precision of monoclonal antibodies allows for tailored treatments, enhancing the effectiveness of therapy and improving patient outcomes. Research institutes leverage monoclonal antibody therapeutics as pivotal tools in advancing medical science. They are crucial for the development of new treatment modalities and the understanding of disease mechanisms. These institutes focus on innovating and improving monoclonal antibody technologies, thus paving the way for the next generation of therapies in various fields of medicine.
Regional Insights
The Americas region, particularly the U.S. and Canada, presents a highly evolved and developed landscape for monoclonal antibody therapeutics, attributed to pioneering research facilities, substantial healthcare spending, and a robust patent environment that protects innovations. Consumer needs in the U.S. are largely driven by a requirement for effective and targeted therapies for cancer, autoimmune diseases, and other chronic conditions. The U.S. Food and Drug Administration (FDA) has been proactive in approving monoclonal antibody treatments, further stimulating market growth. Recent investments mainly focus on cancer research, with biotech companies and the government funding innovative treatments. The European Union (EU) countries contribute significantly to the global monoclonal antibody therapeutics market. High-quality healthcare systems, extensive research networks, and favorable government policies support market growth in the region. Consumer needs in the EU are characterized by an increasing preference for personalized medicine and innovative treatment options. The European Medicines Agency (EMA) facilitates the approval of new therapies, with recent focus areas including oncology and immunology. Stringent regulations for the performance, safety, efficacy, and production of monoclonal antibodies provide a standardized framework for the progress of therapeutics. APAC's monoclonal antibody therapeutics market is expanding rapidly, thanks to substantial government investments in biotechnology and healthcare. The Chinese government's support for biomedical sciences and healthcare reforms has created opportunities for research and the adoption of novel therapies. As one of the leading healthcare markets in Asia, Japan demonstrates strong consumer demand for innovative monoclonal antibody therapies, particularly for aging-related diseases. India's monoclonal antibody therapeutics landscape is emerging, with growth driven by increasing healthcare awareness and improving access to healthcare. Local production and reduced treatment costs are areas of focus to meet consumer needs effectively.
FPNV Positioning Matrix
The FPNV Positioning Matrix is pivotal in evaluating the Monoclonal Antibody Therapeutics Market. It offers a comprehensive assessment of vendors, examining key metrics related to Business Strategy and Product Satisfaction. This in-depth analysis empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success: Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The Market Share Analysis is a comprehensive tool that provides an insightful and in-depth examination of the current state of vendors in the Monoclonal Antibody Therapeutics Market. By meticulously comparing and analyzing vendor contributions in terms of overall revenue, customer base, and other key metrics, we can offer companies a greater understanding of their performance and the challenges they face when competing for market share. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With this expanded level of detail, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Key Company Profiles
The report delves into recent significant developments in the Monoclonal Antibody Therapeutics Market, highlighting leading vendors and their innovative profiles. These include AbbVie Inc., Amgen Inc., Bayer AG, Biogen Inc., Bristol-Myers Squibb Company, Eli Lilly and Company, Envigo, F. Hoffmann-La Roche Ltd, GenScript, GlaxoSmithKline Plc, Johnson & Johnson, Merck Sharp & Dohme Corp.,, Novartis International AG, Pfizer Inc, and Sanofi S.A.
Market Segmentation & Coverage
1. Market Penetration: It presents comprehensive information on the market provided by key players.
2. Market Development: It delves deep into lucrative emerging markets and analyzes the penetration across mature market segments.
3. Market Diversification: It provides detailed information on new product launches, untapped geographic regions, recent developments, and investments.
4. Competitive Assessment & Intelligence: It conducts an exhaustive assessment of market shares, strategies, products, certifications, regulatory approvals, patent landscape, and manufacturing capabilities of the leading players.
5. Product Development & Innovation: It offers intelligent insights on future technologies, R&D activities, and breakthrough product developments.
1. What is the market size and forecast of the Monoclonal Antibody Therapeutics Market?
2. Which products, segments, applications, and areas should one consider investing in over the forecast period in the Monoclonal Antibody Therapeutics Market?
3. What are the technology trends and regulatory frameworks in the Monoclonal Antibody Therapeutics Market?
4. What is the market share of the leading vendors in the Monoclonal Antibody Therapeutics Market?
5. Which modes and strategic moves are suitable for entering the Monoclonal Antibody Therapeutics Market?