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市場調查報告書
商品編碼
1497775
鹼基編輯市場:按組件、類型、技術、應用和最終用途分類 - 2024-2030 年全球預測Base Editing Market by Component (Consumables, Services), Type (DNA Base Editing, RNA Base Editing), Technique, Application, End-use - Global Forecast 2024-2030 |
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基礎編輯市場規模預計2023年為2.7765億美元,2024年達到3.1993億美元,預計2030年將達到7.8547億美元,複合年成長率為16.01%。
鹼基編輯是一種精確基因組編輯技術,可在基因組的特定位置將一個 DNA 鹼基對直接不可逆地改變為另一個鹼基對,無需雙鏈DNA 斷裂或供體DNA 模板即可轉換為.這種創新方法使用融合蛋白,將非催化作用CRISPR-Cas9 與鹼基脫氨酶結合。透過以嚮導 RNA 靶向所需的基因組位點,鹼基編輯酶透過化學修飾 DNA 鹼基來誘導點突變,從而在 DNA 複製後導致鹼基對替換。該技術在治療性基因編輯、疾病遺傳學研究和新農產品開發方面具有潛在應用。該市場包括鹼基編輯工具、服務、消耗品的開發和銷售,以及治療開發、農業和生物技術研究中的各種應用。低音編輯具有廣泛的用途。在治療領域,鹼基編輯用於糾正導致遺傳疾病的單點突變。在農業中,鹼基編輯可以開發具有抗病性和增加產量等有益特性的作物。在研究和開發中,它是了解基因功能和創建人類疾病模型的寶貴工具。鹼基編輯的市場開拓包括開發基因療法的製藥公司、農業生物技術公司和學術研究機構。影響鹼基編輯成長的關鍵因素包括政府資助的增加、對基因組研究的更多關注、擴大基因組在製藥領域的應用以及罕見疾病盛行率的增加。此外,生物技術公司和研究機構之間的策略聯盟正在推動市場擴張。然而,鹼基編輯市場面臨一些限制和挑戰,包括倫理和安全問題以及有關鹼基編輯的嚴格法規。另一方面,鹼基編輯在農業領域的不斷擴大應用以及全球範圍內對個人化醫療日益成長的偏好為鹼基編輯的擴展提供了機會。
主要市場統計 | |
---|---|
基準年[2023] | 27765萬美元 |
預測年份 [2024] | 31993萬美元 |
預測年份 [2030] | 7.8547 億美元 |
複合年成長率(%) | 16.01% |
區域洞察
在北美,美國和加拿大處於鹼基編輯研究和應用的前沿,大型生物技術公司的存在、對基因編輯技術的大量投資以及有利的法規環境有助於鹼基編輯的快速普及。學術機構和生物技術公司之間的合作正在刺激創新,重點是治療遺傳疾病的治療應用。在南美洲,人們對鹼基編輯越來越感興趣,特別是在農業和作物改良領域。巴西和阿根廷等國家正在利用鹼基編輯來提高作物的復原力和生產力,並投資生物技術來加強其龐大的農業部門。由於基因研究的增加和生物技術投資的增加,亞太地區的鹼基編輯市場正在經歷顯著成長。中國、日本等國家走在前列,其中中國在研究成果和專利技術方面處於領先地位。尤其是中國,因其在基因編輯方面取得的顯著進展而成為熱門話題,並積極將鹼基編輯引入臨床研究。日本以其健全的法律規範而聞名,該框架平衡了技術創新和道德考慮。歐洲擁有強大的製藥工業和強大的研究環境,這正在推動鹼基編輯技術的採用。一些歐洲國家正在該領域做出重大貢獻,歐盟(EU)透過各種財政援助積極支持基因編輯研究。隨著中東地區,特別是沙烏地阿拉伯和阿拉伯聯合大公國等國家對醫療創新的投資增加,鹼基編輯正成為醫學研究和潛在治療的工具。在非洲,科技仍在發展,有望解決醫療保健和農業領域的重要挑戰。透過國際夥伴關係和教育措施進行能力建設對於擴大該地區的鹼基編輯至關重要。
FPNV定位矩陣
FPNV 定位矩陣對於評估供應商在基礎編輯市場的定位至關重要。此矩陣提供了對供應商的全面評估,並檢驗了與業務策略和產品滿意度相關的關鍵指標。這種詳細的評估使用戶能夠根據自己的要求做出明智的決定。根據評估結果,供應商被分為代表其成功程度的四個像限:前沿(F)、探路者(P)、利基(N)和重要(V)。
市場佔有率分析
市場佔有率分析是一個綜合工具,可以對基礎編輯市場中供應商的當前狀態進行深入而詳細的評估。透過仔細比較和分析供應商的貢獻,您可以更深入地了解每個供應商的績效以及他們在爭奪市場佔有率時面臨的挑戰。這些貢獻包括整體收益、客戶群和其他重要指標。此外,該分析還提供了對該行業競爭性質的寶貴見解,包括在研究基準年期間觀察到的累積、分散主導地位和合併特徵等因素。有了這些詳細資訊,供應商可以做出更明智的決策並製定有效的策略,以在市場競爭中保持領先地位。
策略分析與建議
策略分析對於尋求在全球市場站穩腳跟的組織至關重要。對目前在基礎編輯市場中的地位進行全面評估,使公司能夠做出符合其長期願望的明智決策。此關鍵評估涉及對組織的資源、能力和整體績效進行徹底分析,以確定核心優勢和需要改進的領域。
[183 Pages Report] The Base Editing Market size was estimated at USD 277.65 million in 2023 and expected to reach USD 319.93 million in 2024, at a CAGR 16.01% to reach USD 785.47 million by 2030.
Base Editing is a form of precision genome editing technique that enables the direct, irreversible conversion of one DNA base pair into another at a specific location in the genome without requiring a double-stranded DNA break or a donor DNA template. This innovative approach uses a fusion protein consisting of a catalytically disabled CRISPR-Cas9 linked to a base deaminase enzyme. By targeting the desired genomic loci with guide RNA, base editors can induce point mutations by chemically modifying the DNA bases, leading to a base pair substitution after DNA replication. This technique offers potential applications in therapeutic gene editing, research on disease genetics, and the development of new agricultural products. This market includes the development and sales of base editing tools, services, consumables, and various applications in therapeutic development, agriculture, and biotechnology research. The applications of base editing are vast and varied. In the therapeutic space, base editing is used to correct single-point mutations that cause genetic diseases. Base editing can develop crops with beneficial traits such as disease resistance or increased yield in agriculture. For research and development, it is an invaluable tool for understanding gene function and creating models of human disease. The market scope for base editing includes pharmaceutical companies developing gene therapies, agricultural biotechnology firms, and academic and research institutions. Key factors influencing the growth of base editing include rising government funding and growing focus on genomic studies, expanding the application of genomics in the pharmaceutical sector, and increasing prevalence of rare diseases. Additionally, strategic collaborations among biotech firms and research organizations fuel market expansion. However, the base editing market faces several limitations and challenges, such as issues associated with ethics and safety and stringent regulations regarding base editing. On the other hand, the expanding application of base editing in the agricultural sector and increasing preference for personalized medicine worldwide present opportunities for expanding base editing.
KEY MARKET STATISTICS | |
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Base Year [2023] | USD 277.65 million |
Estimated Year [2024] | USD 319.93 million |
Forecast Year [2030] | USD 785.47 million |
CAGR (%) | 16.01% |
Regional Insights
In North America, the United States and Canada are at the forefront of base editing research and applications, with the presence of major biotechnology companies, heavy investments in gene editing technologies, and a favorable regulatory environment contributing to the rapid adoption of base editing. Partnerships between academic institutions and biotech firms are fueling innovation, with an emphasis on therapeutic applications to treat genetic disorders. South America has shown an increased interest in base editing, particularly in the areas of agriculture and crop improvement. Countries such as Brazil and Argentina are investing in biotechnology to bolster their vast agricultural sectors, using base editing to enhance crop resilience and productivity. The APAC region is experiencing substantial growth in the base editing market due to the rise in genetic research and increased investments in biotechnology. Countries such as China and Japan are at the forefront, with China leading in research output and patented technologies. China, in particular, has made headlines with significant advancements in gene editing and is actively implementing base editing in clinical research. Japan is notable for its precise regulatory framework, which balances innovation with ethical considerations. Europe boasts a strong pharmaceutical industry and a robust research environment, which propels the adoption of base editing technology. With the European Union's active support for gene editing research through various funding initiatives, several European countries are making notable contributions to the field. The Middle East has seen increased investment in healthcare innovation, particularly in nations such as Saudi Arabia and the United Arab Emirates, where base editing is emerging as a tool for medical research and potential treatments. In Africa, while the technology is still developing, it has the prospect of addressing critical challenges in healthcare and agriculture. Capacity building through international partnerships and educational initiatives is essential for the expansion of base editing in the region.
Market Insights
The market dynamics represent an ever-changing landscape of the Base Editing Market by providing actionable insights into factors, including supply and demand levels. Accounting for these factors helps design strategies, make investments, and formulate developments to capitalize on future opportunities. In addition, these factors assist in avoiding potential pitfalls related to political, geographical, technical, social, and economic conditions, highlighting consumer behaviors and influencing manufacturing costs and purchasing decisions.
FPNV Positioning Matrix
The FPNV positioning matrix is essential in evaluating the market positioning of the vendors in the Base Editing Market. This matrix offers a comprehensive assessment of vendors, examining critical metrics related to business strategy and product satisfaction. This in-depth assessment empowers users to make well-informed decisions aligned with their requirements. Based on the evaluation, the vendors are then categorized into four distinct quadrants representing varying levels of success, namely Forefront (F), Pathfinder (P), Niche (N), or Vital (V).
Market Share Analysis
The market share analysis is a comprehensive tool that provides an insightful and in-depth assessment of the current state of vendors in the Base Editing Market. By meticulously comparing and analyzing vendor contributions, companies are offered a greater understanding of their performance and the challenges they face when competing for market share. These contributions include overall revenue, customer base, and other vital metrics. Additionally, this analysis provides valuable insights into the competitive nature of the sector, including factors such as accumulation, fragmentation dominance, and amalgamation traits observed over the base year period studied. With these illustrative details, vendors can make more informed decisions and devise effective strategies to gain a competitive edge in the market.
Recent Developments
Beam Announces Agreement for Lilly to Acquire Beam's Opt-In Rights to Verve Therapeutics' Base Editing Programs for Cardiovascular Disease
Beam Therapeutics Inc., a prominent provider in base editing technology, has crafted a strategic alliance with Eli Lilly and Company, a pharmaceutical company. Lilly is expected to acquire rights from Beam's updated agreement with Verve Therapeutics, Inc., taking a significant step forward with co-development and co-commercialization options for programs targeting key cardiovascular disease markers like PCSK9 and ANGPTL3-plus an undisclosed target. [Published On: 2023-10-31]
Revvity Expands Access to Base Editing Technology With Aim to Accelerate Discovery to Cure
Revvity Inc. has launched its state-of-the-art Pin-point base editing platform reagents, heralding a new era in CRISPR gene editing technology for preclinical research researchers. With the ability to carry out precision single base changes across various genomic sites, Revvity's Pin-point platform enhances functional genomics, aiding in the optimization of drug development and the simplification of cell line and cell therapy production. [Published On: 2023-09-26]
Researchers develop new base editing tools using AI-predicted protein structure clustering
The research team at the Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, has significantly advanced the field of base editing with their groundbreaking use of artificial intelligence. By leveraging the AlphaFold2 platform to predict and classify structures of deaminase proteins, they have made strides in identifying novel enzymes with unique functions. These enzymes have paved the way for the innovation of custom genetic traits in plants, addressing previous limitations in gene editing due to sequence specificity and organism compatibility. Their research led to the development of various new base editors, which exhibit enhanced efficiencies, minimized off-target effects, and are adaptable to preferred sequence contexts. [Published On: 2023-06-27]
Strategy Analysis & Recommendation
The strategic analysis is essential for organizations seeking a solid foothold in the global marketplace. Companies are better positioned to make informed decisions that align with their long-term aspirations by thoroughly evaluating their current standing in the Base Editing Market. This critical assessment involves a thorough analysis of the organization's resources, capabilities, and overall performance to identify its core strengths and areas for improvement.
Key Company Profiles
The report delves into recent significant developments in the Base Editing Market, highlighting leading vendors and their innovative profiles. These include Addgene, Inc., Beam Therapeutics, Beijing Qi Biodesign Biotechnology Company Limited, Bio Palette Co., Ltd., Creative Biogene, DH Life Sciences, LLC, Editas Medicine, Inc., ElevateBio, LLC, GenScript Biotech Corporation, Intellia Therapeutics, Inc., KromaTiD Inc., Pairwise Plants Services, ProQR Therapeutics N.V., QIAGEN GmbH, Revvity, Inc., Sangamo Therapeutics, Inc., Synthego Corporation, Tecan Group, and TriLink BioTechnologies by Maravai LifeSciences.
Market Segmentation & Coverage