市場調查報告書
商品編碼
1261662
2022-2028年按產品,應用(Western Blotting,Southern Blotting,Northern Blotting 等)、最終用戶、地區展望和預測分列的全球轉移膜市場規模、份額、行業趨勢分析報告Global Transfer Membrane Market Size, Share & Industry Trends Analysis Report By Product, By Application (Western Blotting, Southern Blotting, Northern Blotting and Others), By End-User, By Regional Outlook and Forecast, 2022 - 2028 |
轉移膜市場規模預計到 2028 年將達到 4.189 億美元,預測期內復合年增長率為 4.7%。
印跡是一種將蛋白質和核酸固定在固體基質(通常是尼龍或硝酸纖維素膜)上的方法。 雜交研究的主要技術是核酸印跡。 研究基因表達、組織等的各種實驗方法都是基於核酸在膜上的標記和雜交。
在血液等複雜的生物混合物中,特定蛋白質的鑑定和定量一直是科學和醫學的重要目標。 近年來,檢測基因組DNA中的異常基因在臨床研究和遺傳諮詢中越來越重要。 通過印跡方法檢測不同的蛋白質和核酸序列。 因此,作為分子生物學和臨床研究不可或缺的設備,研究和開發正在取得進展。
COVID-19 影響分析
大流行對全球經濟產生了不利影響,許多市場在封鎖限制的重壓下崩潰。 由於研發項目被關閉,大流行也打擊了轉印膜業務。 冠狀病毒疫苗的研發使轉移膜市場保持活力。 然而,在疫情初期,市場的增長趨勢出現了下行趨勢。
市場增長因素
遺傳和傳染病的增加
雖然最近進行了一些積極的嘗試,但政府通常不會強調對遺傳病和先天缺陷(EMR)的控制。 有一種嚴重的誤解,認為這些問題很少見且無法控制。 據世界衛生組織稱,約有 2% 至 5% 的出生嬰兒受到遺傳病和先天缺陷的影響,它們佔發達國家兒科住院人數的 30% 和嬰兒死亡人數的 50% 以上。 與流行觀點相反,先天性和遺傳性疾病在該地區至少與發達國家一樣普遍。
對基於 RNA 的藥物的需求不斷增長
生物治療學發展最快的領域之一是 RNA 療法。 這些療法建立在強大且適應性強的基礎上,具有幾乎無限的可能性來滿足未滿足的臨床需求。 RNA 療法將改變許多疾病的護理標準。 越來越多的 RNA 療法正在研究和臨床研究中。 RNA 療法的快速擴張歸功於解決了遞送、免疫原性和穩定性問題。 每個領域都有進一步發展和發明的潛力,但到 RNA 療法投入實際使用時,解決方案已經演變。
市場約束
有多種可供選擇的印跡方法
在光譜等聚焦和毛細管等聚焦中,蛋白質按等電點而不是大小分類。 也就是說,在凝膠上形成一個 pH 梯度,這樣當蛋白質達到與其 pI 相對應的 pH 值時,它們就會停止遷移。 該方法具有分辨率高、樣品分析快速、樣品保存方便等優點。 因此,其他選擇的存在與否及其優勢預計會阻礙轉移膜市場的擴張。
產品概覽
根據產品,轉移膜市場分為 PVDF、硝化纖維和尼龍。 PDVF 細分市場以 2021 年最大的收入份額主導轉移膜市場。 這是因為它提供了一種高度可靠且化學惰性的替代其他膜的方法。 PVDF 轉移膜允許更簡單的蛋白質剝離和重新檢測。 該膜的疏水結構使其能夠與蛋白質強烈相互作用,增強蛋白質結合併促進有效運輸。 由於PVDF膜的優勢,其產品被廣泛使用,推動了該細分市場的增長。
交通方式展望
轉印膜市場根據轉印方式分為濕式或槽式轉印、半乾式電印跡(半乾式轉印)、乾式電印跡(乾式轉印)等。 在 2021 年的轉印膜市場中,半乾式電印跡(半乾式轉印)細分市場佔據了相當大的收入份額。 這是因為該技術使用水平盒組件,該組件由浸有轉移緩衝液的過濾器、預濕膜、濾紙和凝膠組成。 這種方法是有益的,因為它使用少量的轉移緩衝液,並允許在室溫下將蛋白質快速轉移到膜上。
樣本類型
按樣品類型,轉印膜市場分為蛋白質印跡、Southern 印跡、Northern 印蹟等。 Western blotting 部分在 2021 年的轉移膜市場中佔據了最大的收入份額。 這是由於這種方法廣泛用於臨床和診斷測試。 蛋白鑑定的高靈敏度和特異性是Western blotting作為分析工具的兩大優勢。 此外,該方法可以在超過 300,000 種蛋白質中準確識別單一目標蛋白質,極大地促進了其在探索性研究應用中的使用。
最終用戶視角
根據最終用戶,轉移膜市場分為生物製藥和製藥公司、學術和研究機構以及診斷實驗室。 2021 年,學術和研究機構部門在轉移膜市場中佔據了重要的收入份額。 這是由於發達國家政府的大力支持和大量研究成果的現成可用性。 此外,隨著印跡方法在知名學術機構中的日益普及,預計未來幾年轉印膜的收入前景將有所增加。
區域展望
按地區劃分,分析了北美、歐洲、亞太地區和 LAMEA 的轉印膜市場。 北美地區將在 2021 年佔據轉移膜市場的最高收入份額。 這是由於研發活動的數量、新藥開發的大量財政支出以及公共和商業機構為研究提供的支持。 此外,該地區慢性病和特殊疾病高發,預計將促進該地區的發展。 預計這些因素將影響預測期內轉移膜市場的擴張。
The Global Transfer Membrane Market size is expected to reach $418.9 Million by 2028, rising at a market growth of 4.7% CAGR during the forecast period.
The term "transfer membrane" describes a group of systems that control how ions and other solutes travel across biological membranes composed of lipid bilayers with embedded proteins. Proteins must be moved from the gel onto a suitable membrane for antibody staining and detection when electrophoresis is finished. The transfer is accomplished by running a current from the gel to the membrane. Transfer membrane has many benefits, including improved staining properties, the ability to be tested repeatedly, and compatibility with a range of detection chemistries, such as radioactive, chromogenic, chemiluminescent, fluorescent, and chemifluorescent methods.
Transfer membranes are the solid phase support employed in blotting procedures to transfer proteins or nucleic acids from gel matrices for detection and analysis. Proteins or nucleic acids are immobilized on a solid matrix membrane after size separation by electrophoresis in a polyacrylamide or agarose gel. This makes it easier to identify certain proteins or nucleic acids using antibodies specific to the target of interest.
Blotting is a method for immobilizing proteins or nucleic acids on a solid substrate, often nylon or nitrocellulose membranes. The primary methodology for hybridization research is nucleic acid blotting. Various experimental approaches to investigate gene expression, organization, etc., are based on the labeling and hybridization of nucleic acids on membranes.
With complicated biological mixes like blood, identifying and quantifying particular proteins has long been a crucial objective in science and medical practice. In recent years, clinical research and genetic counseling have increasingly emphasized the detection of aberrant genes in genomic DNA. Protein and nucleic acid sequences that are distinct are found using blotting methods. They have evolved into crucial molecular biology and clinical research instruments due to their development into susceptible and specialized devices.
COVID-19 Impact Analysis
The international economy was negatively impacted by the pandemic, which led to numerous markets collapsing under the weight of lockdown regulations. As a result of lockdown regulations, numerous research and development projects were halted during the COVID-19 pandemic, which harmed the transfer membrane business. The transfer membrane market was kept alive by research on creating coronavirus vaccines. Still, the market witnessed a downward growth trend in the initial phase of the pandemic.
Market Growth Factors
Increasing prevalence of hereditary and infectious disorders
Despite some recent positive attempts, governments typically do not emphasize controlling genetic illnesses and congenital anomalies (EMR). There are severe misunderstandings that these problems are uncommon and cannot be controlled. According to WHO, around 2% to 5% of all live births are affected by genetic illnesses and congenital anomalies, accounting for up to 30% of pediatric hospital admissions and over 50% of infant fatalities in developed nations. Contrary to popular opinion, congenital and genetic illnesses are at least as prevalent in the area as in more developed parts of the world.
Growing need for RNA-based medicines
A fast-developing area of biotherapeutics is RNA Therapeutics. These treatments are built on a strong, adaptable foundation that offers almost limitless potential to meet unmet clinical requirements. The standard of treatment for numerous illnesses will alter due to RNA Therapeutics. There are an increasing number of RNA medications under research and clinical studies. The fast expansion of RNA treatments results from the issues with delivery, immunogenicity, and stability being resolved. While each area has potential for additional development and invention, the solutions have evolved to the point where RNA Therapies are now practicable.
Market Restraining Factors
Availability of a variety of blotting method substitutes
Spectroscopic isofocusing, proteins are sorted by isoelectric point rather than by size in capillary isofocusing. In other words, the protein will cease migrating when it reaches the pH corresponding to its pI since a pH gradient has been generated throughout the gel. This approach has the advantages of greater resolution, quicker sample analysis, and sample preservation. That is why, the availability of the other alternatives and their advantages are expected to hinder the market expansion of the transfer membrane.
Product Outlook
Based on product, the transfer membrane market is segmented into PVDF, nitrocellulose and nylon. The PDVF segment dominated the transfer membrane market with maximum revenue share in 2021. This is because it provides a very reliable and chemically inert alternative to other membranes. PVDF transfer membranes make it simpler to strip and re-probe proteins. These membranes' hydrophobic structure allows them to interact strongly with proteins, enhancing protein binding and facilitating effective transport. Because of PVDF transfer membranes' benefits, their goods are widely used, which aids in boosting the segment's growth.
Transfer Method Outlook
On the basis of transfer method, the transfer membrane market is divided into wet or tank transfer, semi-dry electro blotting (semi-dry transfer), dry electro blotting (dry transfer) and others. The semi-dry electro blotting (semi-dry transfer) segment procured a substantial revenue share in the transfer membrane market in 2021. This is because this technique uses horizontal cassette assemblies, which are made up of transfer buffer-soaked filters, pre-wetted membranes, filter paper, and gel. The approach is beneficial since it uses less transfer buffer and can swiftly transfer proteins to membranes at room temperature.
Sample Type Outlook
By sample type, the transfer membrane market is classified into western blotting, southern blotting, northern blotting and others. The western blotting segment witnessed the largest revenue share in the transfer membrane market in 2021. This is due to the widespread use of the method for clinical and diagnostic tests. High sensitivity and specificity for protein identification are two benefits of western blotting that make it useful as an analytical tool. Moreover, the method can precisely identify a single target protein among more than 300,000 other proteins, considerably enhancing its use in exploratory research applications.
End User Outlook
Based on the end-user, the transfer membrane market is bifurcated into biopharmaceutical & pharmaceutical companies, academic & research institutes and diagnostic labs. The academic & research institutes segment recorded a significant revenue share in the transfer membrane market in 2021. This is due to the robust government backing and extensive research findings readily accessible in industrialized nations. In addition, the growing penetration of blotting methods among reputable academic research institutes is anticipated to increase the prospects for transfer membranes to generate income in the following years.
Regional Outlook
Region-wise, the transfer membrane market is analyzed across North America, Europe, Asia Pacific, and LAMEA. The North America region generated the highest revenue share in the transfer membrane market in 2021. This is owing to the volume of R & D activities, major financial expenditures made in developing new pharmaceuticals, and support provided by both public and commercial entities for research. Moreover, the increased incidence of chronic illnesses and specific diseases in the area is projected to boost the region's development. These factors are anticipated to impact the transfer membrane market's expansion in the projected period.
The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Thermo Fisher Scientific, Inc., Danaher Corporation, Bio-Rad Laboratories, Inc., Merck KGaA, PerkinElmer, Inc., Abcam Plc, Santa Cruz Biotechnology, Inc., ATTO Corporation, Azure Biosystems, Inc., and GVS S.p.A.
Strategies Deployed in Transfer Membrane Market
Oct-2022: Thermo Fisher Scientific revealed Gibco CTS DynaCellect magnetic separation system. The system features cell isolation, activation and depletion. DynaCellect separate the right cells and minimize failures in manufacturing. The launch is aimed at providing a scalable, flexible, automated and closed system for cell therapy manufacturing.
Jan-2022: Thermo Fisher completed its acquisition of PeproTech, a recombinant proteins provider. With this acquisition, the company aimed to expand its capabilities in order to meet the rising demand for gene therapy and the growth of the cell market. In addition, this acquisition would also complement the cell culture media products of Thermo Fisher through the addition of applications. PeproTech's recombinant proteins offering, which would allow Thermo Fisher to offer substantial benefits to its customers via an integrated portfolio.
Jun-2021: Danaher completed the acquisition of Aldevron, a US-based biotech business. With this acquisition, Danaher would expand its abilities into the crucial field of genomic medicine and help consumers and their essential task to obtain more life-saving treatments and vaccines to market quickly.
May-2021: PerkinElmer took over Nexcelom Bioscience, a Massachusetts-based biotechnology company. Under this acquisition, the integration would broaden PerkinElmer's efforts to support the government, academic, and biopharmaceutical organizations in developing their comprehensive workflows and help efforts to boost time to market and time to target other beneficial therapies.
Jul-2020: Merc expanded its footprint by opening a lab in Shanghai. M Lab Collaboration Center provides customizable solutions made for the Life Science community in China to help advance drug development.
Apr-2020: Bio-Rad Laboratories took over Celsee, an instruments and consumables provider. With this acquisition, the company aimed to expand its reach throughout the world in order to meet the rising demands of customers for single-cell analysis and precision medicine in order to offer improved insight into the disease along with its diagnosis as well as treatment.
Feb-2018: PerkinElmer, Inc. took over RHS Limited, develops and markets biotechnology technologies. Through this acquisition, the company aimed to expand its genomic research offerings.
Market Segments covered in the Report:
By Product
By Transfer Method
By Application
By End-User
By Geography
Companies Profiled
Unique Offerings from KBV Research
List of Figures