市場調查報告書
商品編碼
1576505
生物反應器市場規模,佔有率,預測,趨勢分析:按類型、生物製程、效用、規模、細胞類型、應用、使用者 - 到 2031 年的全球預測Bioreactors Market Size, Share, Forecast, & Trends Analysis by Type, Bioprocess, Usability, Scale, Cell Type, Application, User - Global Forecast to 2031 |
預計到2031年,全球生物反應器市場將達到399.6億美元,2024年至2031年複合年增長率為10.1%。
該報告基於全面的一手和二手研究以及對市場情景的深入分析,深入瞭解了生物反應器市場的關鍵推動因素、市場限制、機會和課題。市場成長的推動因素包括生物製藥工廠的擴張、製藥業的成長、藥品研發支出的增加、生物相似藥的採用增加以及製藥和生物技術領域一次性技術的採用增加。然而,生物製藥開發和製造過程的複雜性以及生物製藥製造所需的高資本需求限制了市場成長。
此外,生物反應器技術的進步以及個人化藥物以及細胞和基因療法的更多採用預計將創造市場成長機會。然而,使用一次性生物反應器的生物製造過程中與可提取物和可浸出物(E&L) 相關的風險、擴大生物製藥過程的限制、標準化一次性生物反應器設計的需要、與廢棄生物反應器相關的環境問題是其中一些因素。
從產品來看,預計到 2024 年,連續攪拌釜生物反應器領域將佔據生物反應器市場的最大佔有率,達到 31%。該領域的巨大市場佔有率歸因於連續攪拌罐生物反應器的技術進步以及由於其與其他生物反應器相比具有優越的傳熱性能而能夠處理高濃度反應物。此外,市場參與者正在增強生物反應器設計,以便與現有流動系統無縫整合。例如,2024年10月,Vapourtec Ltd.(英國)推出了專為連續製程合成而設計的連續攪拌槽生物反應器。
基於生物工藝,預計到 2024 年,分批/補料分批細分市場將佔據生物反應器市場的最大佔有率。此細分市場的龐大市場佔有率歸因於分批/補料分批生物製程的優勢,例如高生產率、簡化的生物製程管理和降低的污染風險。批次持續時間非常適合快速實驗、加速上游流程和提高整體生產力。
按細胞類型劃分,預計到 2024 年,哺乳動物細胞將在生物反應器市場中佔據最大佔有率。該細分市場的巨大市場佔有率歸因於對單株抗體和治療性蛋白質等複雜生物分子的商業和研究生物生產的日益關注。此外,涉及哺乳動物細胞的臨床研究的增長促使一次性生物反應器的廣泛採用。
基於易用性,預計到 2024 年,可重複使用的生物反應器領域將在生物反應器市場中佔據更大的佔有率。該領域的巨大市場佔有率歸因於大規模製造的增加,而可重複使用的生物反應器由於其成本效益和適合大批量生產而得到越來越多的採用。此外,與廢物處理相關的高成本和監管限制正在推動可重複使用生物反應器的廣泛採用。
以規模計算,中試規模生物反應器(10L-200L)領域預計將創下市場最高複合年增長率。中試規模生物反應器是容量從 10L 到 200L 不等的系統,可提供多種變化和客製化。中試生物反應器在食品、製藥和化妝品行業中有著廣泛的應用,主要用於在大規模生產之前測試和完善生物製程。對商業生物生產的需求不斷增長將推動中試規模生物加工的採用。這是因為這些生物反應器對於評估其在接近工業環境的條件下的效率、可擴展性和性能至關重要。
基於自動化,自動化生物反應器領域預計將在 2024 年佔據更大的市場佔有率。該細分市場的巨大市場佔有率歸因於自動化生物反應器提供的優勢,例如提高製程品質、減少錯誤、優化製程控制和降低成本。自動化生物反應器透過即時監控和數據豐富的品質控制幫助提高品質和生產力。簡化程序和實驗並快速檢測過程偏差。
從應用來看,預計到 2024 年商業生產領域將佔據生物反應器市場的很大佔有率。商業生產包括單株抗體 (mAb) 生產、細胞和基因治療生產、疫苗生產、血漿分級分離和重組蛋白生產。該細分市場的巨大市場佔有率是由生物製藥的日益普及、旨在加速生物仿製藥採用的有利監管改革以及基因療法開發投資的增加所推動的。
從最終用戶來看,生物製藥製造商領域預計將在 2024 年佔據最大佔有率。近年來,由於生物製藥需求的增加、慢性病盛行率的增加、製藥和生物技術公司研發支出的增加以及最近針對慢性和罕見疾病的生物製劑的推出,生物製藥製造商經歷了顯著增長。各國政府正在主動投資、向生物製藥公司提供贈款和資金,用於生物製藥的製造和研發,並共同開發可持續的生物製造方法。這些因素促使生物製藥製造商擴大採用生物反應器,從而為該領域帶來了巨大的市場佔有率。
對全球生物反應器市場區域狀況的詳細分析為五個關鍵區域(北美、歐洲、亞太地區、中東和非洲以及拉丁美洲)以及每個區域的主要國家提供了詳細的定性和定量見解。 。
到2024年,北美預計將佔據全球生物反應器市場的最大佔有率,達到34%,其次是歐洲、亞太地區、拉丁美洲以及中東和非洲。北美市場佔有率大的原因在於主要生物製藥公司的存在、研發投入高、政府和監管機構對促進生物製藥使用的支持以及生物製藥公司擴大生產能力的努力。
(註:提供前5名公司的SWOT分析)
Bioreactors Market Size, Share, Forecast, & Trends Analysis by Type (continuous Stirred Tank, Photobioreactor) Bioprocess (Batch, Continuous) Usability (Reusable, Single-use) Scale (Pilot, Industrial) Cell Type, Application, User-Global Forecast to 2031.
The global bioreactors market is projected to reach $39.96 billion by 2031, at a CAGR of 10.1% from 2024 to 2031.
Following a comprehensive primary and secondary study and an in-depth analysis of the market scenario, this report provides insights into the key drivers, restraints, opportunities, and challenges of the bioreactors market. The growth of this market is driven by the expansion of biopharmaceutical plants, the growth of the pharmaceuticals sector, increased R&D expenditures in pharmaceuticals, the rising adoption of biosimilars, and the growing adoption of disposable technologies in the pharmaceutical and biotechnology sectors. However, the complex development & manufacturing processes of biopharmaceuticals and high capital requirements for biopharmaceutical production restrain the market's growth.
Moreover, advancements in bioreactor technologies and the rising adoption of personalized medicines and cell & gene therapies are expected to create market growth opportunities. However, risks associated with extractables and leachables (E&L) in biomanufacturing processes using single-use bioreactors, limitations in scaling up biopharmaceutical processes, the need to standardize designs for single-use bioreactors, and environmental concerns related to the disposal of single-use bioreactors are some of the challenges impacting the market's growth.
Based on product, in 2024, the continuous stirred-tank bioreactors segment is expected to account for the largest share of 31% of the bioreactors market. This segment's large market share can be attributed to technological advancements in continuous stirred-tank bioreactors and their capability to handle higher concentrations of reactants due to their superior heat transfer properties compared to other bioreactors. Additionally, market players are enhancing bioreactor designs to integrate seamlessly with existing flow systems. For instance, in October 2024, Vapourtec Ltd. (U.K.) launched a continuous stirred-tank bioreactor designed for continuous process synthesis, specifically designed to work alongside existing flow-chemistry systems.
Based on bioprocess, in 2024, the batch/fed-batch segment is expected to account for the largest share of the bioreactors market. This segment's large market share can be attributed to the advantages of batch/fed-batch bioprocessing, including high productivity, simplified management of bioprocesses, and reduced risks of contamination. The duration of batch processing is ideal for rapid experimentation and accelerates upstream processes, thereby enhancing overall productivity.
Based on cell type, in 2024, the mammalian cells segment is expected to account for the largest share of the bioreactors market. This segment's large market share can be attributed to the increasing focus on commercial and research bioproduction for complex biomolecules such as monoclonal antibodies and therapeutic proteins. Additionally, the growth in clinical research involving mammalian cells has led to their widespread adoption in single-use bioreactors.
Based on usability, in 2024, the reusable bioreactors segment is expected to account for the larger share of the bioreactors market. This segment's large market share can be attributed to the increase in large-scale manufacturing, where reusable bioreactors are increasingly adopted due to their cost efficiency and suitability for handling high volumes of production. Moreover, the high costs and regulatory restrictions associated with waste disposal drive the increased adoption of reusable bioreactors.
Based on scale, the pilot scale bioreactors (10L-200L) segment is slated to register the highest CAGR in the market. Pilot scale bioreactors are systems that are between the capacity of 10L-200L and include multiple variations and customizations. They find extensive application in the food, pharmaceutical, and cosmetics industries, primarily for testing and refining bioprocesses before full-scale production. The increasing demand for commercial bioproduction drives the adoption of pilot scale bioprocessing, as these bioreactors are crucial in assessing efficiency, scalability, and performance under conditions closely resembling industrial settings.
Based on automation, in 2024, the automated bioreactors segment is expected to account for the larger share of the market. This segment's large market share can be attributed to the benefits offered by automated bioreactors, including enhanced process quality, reduced errors, optimized process control, and cost savings. Automated bioreactors contribute to improved quality and productivity through real-time monitoring and data-rich quality control. They streamline procedures and experiments, ensuring swift detection of deviations in processes.
Based on application, in 2024, the commercial production segment is expected to account for the larger share of the bioreactors market. The commercial production consists of monoclonal antibodies (mAb) production, cell & gene therapy production, vaccine manufacturing, plasma fractionation, and recombinant protein production. This segment's large market share can be attributed to the growing adoption of biopharmaceuticals, favorable regulatory reforms aimed at promoting the adoption of biosimilars, and rising investments in developing gene therapies.
Based on end user, in 2024, the biopharmaceutical manufacturers segment is expected to account for the largest share of the market. Biopharmaceutical companies have witnessed significant growth in recent years due to the increasing demand for biopharmaceuticals, growing incidence of chronic diseases, rising R&D expenditure by pharmaceutical & biotechnology companies, and recent launches of biologics for chronic & rare diseases. Governments of various countries are taking initiatives by making investments and providing grants & funds to biopharmaceutical companies for the manufacture and R&D of biopharmaceuticals, along with several companies that are collaborating to develop sustainable methods for biomanufacturing. These factors contribute to the increased adoption of bioreactors among biopharmaceutical manufacturers, contributing to the segment's large market share.
An in-depth analysis of the geographical scenario of the global bioreactors market provides detailed qualitative and quantitative insights into five major geographies (North America, Europe, Asia-Pacific, the Middle East & Africa, and Latin America) along with the coverage of major countries in each region.
In 2024, North America is expected to account for the largest share of 34% of the global bioreactors market, followed by Europe, Asia-Pacific, Latin America, and the Middle East & Africa. North America's significant market share can be attributed to the presence of large biopharmaceutical companies, high R&D investments, support from government and regulatory authorities to promote the use of biopharmaceuticals, and initiatives by biopharmaceutical companies to expand their manufacturing capacities.
The key players operating in the global bioreactors market are Thermo Fisher Scientific, Inc. (U.S.), METTLER TOLEDO (U.S.), Merck KGaA (Germany), Eppendorf AG (Germany), Sartorius AG (Germany), Danaher Corporation (U.S.), Donaldson Company, Inc. (U.S.), BBI-Biotech GmbH (Germany), Infors AG (Switzerland), and Pharsol Ltd. (Slovenia).
Bioreactors Market-by Product
Bioreactors Market-by Bioprocess
Bioreactors Market-by Cell Type
(Other cell types include plant cells and insect cells)
Bioreactors Market-by Usability
Bioreactors Market-by Scale
Bioreactors Market-by Automation
Bioreactors Market-by Application
Bioreactors Market-by End User
Bioreactors Market-by Geography
(Note: SWOT analysis of the top 5 companies will be provided.)