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膝關節軟骨修復市場增長、趨勢、COVID-19 的影響和預測 (2023-2028)

Knee Cartilage Repair Market - Growth, Trends, and Forecasts (2023 - 2028)
出版日期: | 出版商: Mordor Intelligence | 英文 120 Pages | 商品交期: 2-3個工作天內

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簡介目錄

膝關節軟骨修復市場預計在預測期內（2022 年至 2027 年）的複合年增長率為 6.2%。

在 COVID-19 大流行期間，所研究的市場因供應鏈問題和漫長的等待時間而受到不利影響。 例如，2021 年 8 月，開展了一項名為“COVID-19 疫情對骨科手術的影響”的研究。 根據對大流行第一年的全國分析，在大流行的第一年，智利的骨科手術數量下降了 22.8%。 所有外科手術都會受到不利影響，骨折和外傷手術受影響最小。 膝關節置換術 (-64%) 的副作用最大，其次是髖關節置換術 (-41%) 和膝關節韌帶重建術 (-44%)。 COVID-19 的爆發減少了 2020 年骨科手術的數量，但它肯定對擇期手術產生了重大的負面影響，因為公共衛生網絡的恢復速度比私人設施慢。 等待名單預計會增加，擴大骨科手術的差距，這最終會影響未來幾年的市場增長率。

交通事故和運動損傷的增加以及人口老齡化以及對微創手術的日益偏好等因素正在推動市場增長。 例如，2021 年 10 月，世界衛生組織發表了一篇題為“年齡與健康”的文章，其中指出，到 2030 年，全球將有六分之一的人超過 60 歲。 60 歲及以上人口的比例將從 2020 年的 10 億增加到 14 億。 到 2050 年，全球 60 歲及以上人口將翻一番，達到 21 億。 從 2020 年到 2050 年，80 歲及以上的人口數量預計將增加兩倍，達到 4.26 億。 衰老會損害膝關節健康，增加損傷膝關節軟骨的機會，因此需要治療。 因此，老年人口的增加將推動膝關節手術的需求並推動市場的增長。

同樣，交通事故的增加也是推動市場增長的因素之一。 例如，2021 年 10 月，美國國家公路安全管理局 (ANSR) 報告稱，與兩個月前的下降相比，死亡人數增加了 42.5%，重傷事故佔 2.4%，輕傷事故佔 11.6%與8月相比上升了9.1%，宣布該指數出現轉折惡化。 文件顯示，2021年8月葡萄牙道路共發生交通事故2996起，死亡57人，重傷217人，輕傷3644人。 因此，受傷人數的增加將增加對膝關節軟骨治療的需求，預計這將推動未來幾年的市場增長。

同樣，對微創手術的日益偏愛預計也將促進市場增長。 例如，2021 年 1 月，發表了一項名為“使用擴展關節鏡進行微創膝關節手術的增強現實導航”的研究，指出在微創膝關節手術中，外科醫生可以使用手術工具和關節鏡通過一個小切口插入。並且治療由二維關節鏡圖像輔助。 與 2D 關節鏡導航相比，所提出的增強現實導航在膝關節模型和體外豬膝關節實驗中分別將指向誤差減少了 2.10 毫米和 2.70 毫米。 因此，隨著技術的進步，對微創手術的偏好將會增加，從而支持市場的增長。

此外，2021 年 7 月，Hyalex Orthopedics, Inc. 的 HYALEX 軟骨系統獲得了美國食品和藥物管理局 (FDA) 授予的突破性器械稱號。 HYALEX 軟骨系統旨在修復軟骨缺損並恢復□□因膝關節軟骨或骨缺損而需要手術的患者的功能。

因此，由於上述因素，市場有望在未來增長。 然而，高昂的治療成本可能會阻礙預測期內的市場增長。

膝關節軟骨修復市場趨勢

在預測期內，關節鏡軟骨成形術領域預計將佔據重要的市場份額

軟骨成形術用於潤滑膝蓋中受損的軟骨並減少關節內的摩擦。 越來越多的研究調查等因素正在推動這一領域的增長。 已經發表了各種研究報告，以提供對所研究細分市場的見解。 例如，2021 年 8 月發表了一篇題為“關節鏡後軟骨下不全骨折的膝關節屈服於關節成形術的高轉化率”的研究論文，指出膝關節的關節鏡下軟骨下不全骨折 (SIFKs) 受內側損傷影響最大隔間。他說這經常發生。 這些患者 (75%) 的半月板根部和橈骨破裂很明顯。 最終，關節病進展 (33%)，最終關節置換手術的發生率很高。

同樣，2022 年 1 月發表的另一項名為“射頻在關節軟骨病變治療中的關節鏡應用”的研究發現，接受膝關節鏡檢查的患者中，超過 60% 的軟骨厚度不全。缺陷是可檢測的，並且髕骨外橋 III 級病變占主導地位。 在這項研究中，我們調查了 15 名接受膝關節鏡射頻軟骨成形術的患者。 與術前相比，這些患者的臨床結果顯著改善。

此外，產品發布也在推動市場的增長。 例如，2021 年 2 月，美國食品和藥物管理局授予 Geistlich Pharma 的 Chondro-Gide 關節軟骨覆蓋物突破性裝置 (BDD)。 Chondro Guide 是一種膠原蛋白膜，用於單步軟骨修復技術。

因此，由於上述因素，市場預計在預測期內會出現增長。

北美有望在預測期內主導市場

膝關節軟骨修復市場以北美為中心。 疾病發病率增加、技術進步、研究和資助等因素正在推動市場增長。 正在研究各種新技術以提供更好的治療方法。 例如，2021 年 10 月，一項名為“用於椎間盤和膝關節軟骨修復的 3D 生物打印植入物”的研究發表，表明在過去的二十年中，人們對軟骨組織工程領域的興趣越來越大，這已被用於開發細胞、生長因子 (GF)，稱 3D 生物打印等技術可用於使用生物相容性材料的組合來生成功能性結構。 3D 生物打印使我們能夠定制開發結構的機械性能，以確保所需的剛度來支撐重量，同時在植入後保持所需的靈活性。

同樣，2021 年 12 月發表的另一項題為“使用多階段卷積神經網絡自動分割膝關節軟骨和骨骼：來自骨關節炎倡議的數據”的研究發現，MR 他們學習了一個框架，可以從圖像中自動分割膝關節軟骨和骨骼，實現不同疾病嚴重程度的高效準確量化。 這項研究由加拿大自然科學和工程研究委員會資助。

此外，產品發布是推動該地區增長的另一個因素。 例如，2020 年 12 月，全球微創骨科技術領導者 Arthrex 在美國食品和藥物管理局批准其 SwiveLock ACL 修復錨後，宣布推出 SwiveLock ACL 修復套件。。 該套件是首批獲得 FDA 批准用於前交叉韌帶斷裂初級修復的套件之一。 預計此類發布將促進市場增長。

因此，此類進步可能會在未來以更高效的產品促進市場增長。

膝關節軟骨修復市場競爭者分析

市場部分分散，由幾個主要參與者組成。 從市場份額的角度來看，一些主要參與者主導著市場。 目前主導市場的公司包括 B. Braun Melsungen AG、ISTO Technologies, Inc.、Smith & Nephew、Stryker 和 Zimmer Biomet Holdings, Inc.。

其他好處

  • Excel 格式的市場預測 (ME) 表
  • 三個月的分析師支持

內容

第1章介紹

  • 研究假設和市場定義
  • 調查範圍

第2章研究方法論

第 3 章執行摘要

第4章市場動態

  • 市場概覽
  • 市場驅動力
    • 老年人口增加
    • 交通事故和運動傷害增加
    • 越來越喜歡微創手術
  • 市場製約因素
    • 高昂的治療費用
  • 波特的五力分析
    • 新進入者的威脅
    • 買方/消費者議價能力
    • 供應商的議價能力
    • 替代品的威脅
    • 競爭公司之間的敵對關係

第 5 章市場細分（基於價值的市場規模：百萬美元）

  • 通過申請
    • 關節鏡軟骨移植
    • 自體培養軟骨移植
    • 基於細胞的軟骨表面重修
    • 骨軟骨成形術
    • 其他
  • 最終用戶
    • 醫院
    • 門診手術中心
    • 骨科診所
  • 按地區
    • 北美
      • 美國
      • 加拿大
      • 墨西哥
    • 歐洲
      • 德國
      • 英國
      • 法國
      • 意大利
      • 西班牙
      • 其他歐洲地區
    • 亞太地區
      • 中國
      • 日本
      • 印度
      • 澳大利亞
      • 韓國
      • 其他亞太地區
    • 中東
      • 海灣合作委員會
      • 南非
      • 其他中東地區
    • 南美洲
      • 巴西
      • 阿根廷
      • 其他南美洲

第6章競爭格局

  • 公司簡介
    • Anika Therapeutics, Inc
    • Arthrex, Inc
    • B. Braun Melsungen AG
    • CartiHeal, Inc
    • CONMED Corporation
    • ISTO Technologies, Inc.
    • Johnson & Johnson（DePuy Synthes）
    • MEDIPOST Co. Ltd.
    • Smith & Nephew
    • Stryker
    • Vericel Corporation
    • Zimmer Biomet Holdings, Inc.

第7章 市場機會與今後動向

簡介目錄
Product Code: 90525

The Knee Cartilage Repair Market is projected to register a CAGR of 6.2% during the forecast period (2022- 2027).

During the COVID-19 pandemic, the studied market was adversely affected due to supply chain issues and long waiting times. For instance, in August 2021, a research study titled "Impact of the COVID-19 Outbreak on Orthopedic Surgery: A Nationwide Analysis of the First Pandemic Year" stated that the number of orthopedic surgeries fell by 22.8% during the first year of the pandemic in Chile. All surgical procedures were adversely affected, with fracture and trauma surgeries being the least affected. The maximum adverse impact was seen in knee arthroplasty (-64%), followed by hip arthroplasty (-41%) and knee ligament reconstruction (-44%). The COVID-19 outbreak reduced the number of orthopedic procedures during 2020, as public health networks did have a more significant adverse impact on elective surgeries due to a slower recovery than private institutions. An increase in the waiting list should be expected, which will widen the access gap to orthopedic surgery, ultimately impacting the market growth rate over the coming years.

Factors such as the increasing geriatric population coupled with increasing road and sports-related injuries and a rising preference for minimally invasive surgeries are driving the market growth. For instance, an article published by the World Health Organization titled "Age and Health" in October 2021 stated that by 2030, 1 in 6 people worldwide would be 60 years or older. The share of the population aged 60 years and over will increase from 1 billion in 2020 to 1.4 billion. By 2050, the world's population of people aged 60 years and older will double (to 2.1 billion). The number of people aged 80 years or older is expected to triple between 2020 and 2050 to reach 426 million. Aging may hurt knee health, and thus, there will be an increased chance of knee cartilage damage and thus it will require treatment. Hence, growth in the geriatric population, thereby drive the demand for knee surgeries, in turn boosting the market's growth.

Similarly, rising road accidents are another factor augmenting the market's growth. For instance, in October 2021, the National Road Safety Authority (ANSR) stated that there was a worsening in the evolution of the indicators, with a growth of 42.5% in fatalities, in contrast to the reductions of the two previous months, and an increase of 9.1% in the number of accidents, from 2.4% for serious injuries and 11.6% for minor injuries, compared to August 2020. According to the same document, in August 2021, there were 2,996 road accidents on Portuguese roads, which caused 57 deaths, 217 serious injuries, and 3,644 minor injuries. As a result, rising injuries will increase the demand for knee cartilage treatment, driving market growth in the coming years.

Similarly, a rising preference for minimally invasive surgeries would increase market growth. For instance, in January 2021, a research study published titled "Augmented reality navigation for minimally invasive knee surgery using enhanced arthroscopy" stated that during minimally invasive knee surgery, surgeons insert surgical instruments and arthroscopy through small incisions and implement treatment assisted by 2D arthroscopic images. Compared with 2D arthroscopic navigation, the proposed augmented reality navigation reduced the targeting errors by 2.10 mm and 2.70 mm for knee phantom and in vitro swine knee experiments, respectively. Thus, with technological advancements, the preference for minimally invasive surgeries will increase and support the market's growth.

Additionally, in July 2021, the HYALEX Cartilage System by Hyalex Orthopaedics, Inc. was granted Breakthrough Device Designation by the United States Food and Drug Administration (FDA). The HYALEX Cartilage System is intended to repair cartilage defects and restore function for patients with loss of knee articular cartilage and bone requiring surgery.

Thus, the abovementioned factors will increase the market's growth in the upcoming period. However, the high cost of treatment may hinder the market's growth over the forecast period.

Knee Cartilage Repair Market Trends

Arthroscopic Chondroplasty Segment is Expected to Hold a Significant Market Share Over the Forecast Period

Chondroplasty is performed to smooth damaged cartilage in the knee to lessen friction in the joint. Factors such as increasing research studies are driving the segment's growth. Various research studies have been published to provide insight into the studied segment. For instance, in August 2021, a published research paper titled "Post-arthroscopic Subchondral Insufficiency Fractures of the Knee Yield High Rate of Conversion to Arthroplasty" stated that post-arthroscopic subchondral insufficiency fracture of the knee (SIFK) most commonly occurs in the medial compartment. Meniscal root and radial tears in these patients are notable (75%). Ultimately, there is a high rate of progression of arthrosis (33%) and eventual conversion to arthroplasty.

Similarly, another research study published in January 2022, titled "The Arthroscopic Application of Radiofrequency in Treatment of Articular Cartilage Lesions," stated that knee arthroscopy partial-thickness cartilage defects can be detected in more than 60% of the cases that received knee arthroscopy, with Outerbridge Grade III lesions of the patella being the dominant one. The study investigated 15 patients who underwent knee arthroscopic radiofrequency chondroplasty. The clinical results of these patients were significantly improved compared with their preoperative status.

Additionally, the launch of products is also augmenting the market's growth. For instance, in February 2021, the United States Food and Drug Administration granted Chondro-Gide articular cartilage cover by Geistlich Pharma a Breakthrough Device (BDD). Chondro-Gide is a collagen membrane used in a single-step cartilage repair technique.

Thus, owing to the abovementioned factors, the market segment is expected to show growth over the forecast period.

North America is Expected to Dominate the Market Over the Forecast Period

The North American market is dominating the knee cartilage repair market. Factors such as the increasing incidence of diseases, technological advancements, research studies, and grants are increasing the market's growth. Various new technologies have been considered to provide better care. For instance, in October 2021, a research study published titled "3D Bioprinted Implants for Cartilage Repair in Intervertebral Discs and Knee Menisci" stated that there had been increasing interest in the past two decades in the area of cartilage tissue engineering where methods like 3D bioprinting may be implemented to generate functional constructs using a combination of cells, growth factors (GF), and biocompatible materials. 3D bioprinting allows for the modulation of the mechanical properties of the developed constructs to maintain the required flexibility following implantation while also providing the stiffness needed to support body weight.

Similarly, another research study published in December 2021 titled "Automatic knee cartilage and bone segmentation using multi-stage convolutional neural networks: data from the osteoarthritis initiative" stated that the framework learns to automatically segment knee cartilage tissues and bones from MR images acquired with two sequences, producing efficient, accurate quantifications at varying disease severities. The study received a grant from Canada's Natural Sciences and Engineering Research Council.

Furthermore, product launches are another factor in the growth of the region. For instance, in December 2020, Arthrex, a global leader in minimally invasive orthopedic technology, announced the launch of the SwiveLock ACL Repair Kit, following clearance by the United States Food and Drug Administration of the SwiveLock anchor for ACL repair. It is one of the first FDA-cleared kits for the primary repair of anterior cruciate ligament (ACL) tears. Such launches would increase the market's growth.

Hence, with such advancements, the market's growth would increase due to more efficient products in the future.

Knee Cartilage Repair Market Competitor Analysis

The market is partially fragmented and consists of several major players. In terms of market share, a few major players dominate the market. Some of the companies which are currently dominating the market are B. Braun Melsungen AG, ISTO Technologies, Inc., Smith & Nephew, Stryker, and Zimmer Biomet Holdings, Inc., among others.

Additional Benefits:

  • The market estimate (ME) sheet in Excel format
  • 3 months of analyst support

TABLE OF CONTENTS

1 INTRODUCTION

  • 1.1 Study Assumptions and Market Definition
  • 1.2 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS

  • 4.1 Market Overview
  • 4.2 Market Drivers
    • 4.2.1 Increasing Geriatric Population
    • 4.2.2 Increasing Road and Sports Related Injuries
    • 4.2.3 Increasing Preference for Minimally Invasive Surgeries
  • 4.3 Market Restraints
    • 4.3.1 High Cost of Treatment
  • 4.4 Porter's Five Forces Analysis
    • 4.4.1 Threat of New Entrants
    • 4.4.2 Bargaining Power of Buyers/Consumers
    • 4.4.3 Bargaining Power of Suppliers
    • 4.4.4 Threat of Substitute Products
    • 4.4.5 Intensity of Competitive Rivalry

5 MARKET SEGMENTATION (Market Size by Value - USD million)

  • 5.1 By Application
    • 5.1.1 Arthroscopic Chondroplasty
    • 5.1.2 Autologous Chondrocyte Implantation
    • 5.1.3 Cell-based Cartilage Resurfacing
    • 5.1.4 Osteochondral Grafts Transplantation
    • 5.1.5 Others
  • 5.2 By End User
    • 5.2.1 Hospitals
    • 5.2.2 Ambulatory Surgical Centers
    • 5.2.3 Orthopedic Clinics
  • 5.3 Geography
    • 5.3.1 North America
      • 5.3.1.1 United States
      • 5.3.1.2 Canada
      • 5.3.1.3 Mexico
    • 5.3.2 Europe
      • 5.3.2.1 Germany
      • 5.3.2.2 United Kingdom
      • 5.3.2.3 France
      • 5.3.2.4 Italy
      • 5.3.2.5 Spain
      • 5.3.2.6 Rest of Europe
    • 5.3.3 Asia-Pacific
      • 5.3.3.1 China
      • 5.3.3.2 Japan
      • 5.3.3.3 India
      • 5.3.3.4 Australia
      • 5.3.3.5 South Korea
      • 5.3.3.6 Rest of Asia-Pacific
    • 5.3.4 Middle-East
      • 5.3.4.1 GCC
      • 5.3.4.2 South Africa
      • 5.3.4.3 Rest of Middle-East
    • 5.3.5 South America
      • 5.3.5.1 Brazil
      • 5.3.5.2 Argentina
      • 5.3.5.3 Rest of South America

6 COMPETITIVE LANDSCAPE

  • 6.1 Company Profiles
    • 6.1.1 Anika Therapeutics, Inc
    • 6.1.2 Arthrex, Inc
    • 6.1.3 B. Braun Melsungen AG
    • 6.1.4 CartiHeal, Inc
    • 6.1.5 CONMED Corporation
    • 6.1.6 ISTO Technologies, Inc.
    • 6.1.7 Johnson & Johnson (DePuy Synthes)
    • 6.1.8 MEDIPOST Co. Ltd.
    • 6.1.9 Smith & Nephew
    • 6.1.10 Stryker
    • 6.1.11 Vericel Corporation
    • 6.1.12 Zimmer Biomet Holdings, Inc.

7 MARKET OPPORTUNITIES AND FUTURE TRENDS