市場調查報告書
商品編碼
1417591
全球頭頸癌市場評估:依治療類型、給藥途徑、藥物類別、銷售管道、地區、機會與預測(2017-2031)Head and Neck Cancer Market Assessment, By Therapy Type By Route of Administration, By Drug Class, By Distribution Channel By Region, Opportunities and Forecast, 2017-2031F |
全球頭頸癌市場規模預計到2023年將達到22.5億美元,到2031年將達到37.6億美元,2024-2031年預測期間複合年增長率為6.62%。隨著對疾病和治療方法的了解的增加,市場正在顯示出顯著的成長和演變。
頭頸癌,包括發生在口腔、咽部和喉部的腫瘤,給全世界帶來了巨大的醫療負擔。吸菸和飲酒、人類乳突病毒 (HPV) 感染和環境因素等危險因子會導致這些癌症的發生。全球頭頸癌市場受到發病率上升、診斷方法改進和創新治療方法開發等因素的推動。免疫療法和標靶療法的最新進展為患者帶來了希望。這些新療法,加上對精準醫療和個人化治療計劃的日益關注,正在改變市場。市場上的主要參與者正在投資於研發,以推出新的治療方法並擴大其產品組合。此外,人們對早期檢測和預防重要性的認識不斷提高也促進了市場的成長。全球頭頸癌市場充滿活力且快速發展,重點是透過先進的治療方案和早期幹預策略來改善患者的治療結果。
Elsevier發表的一篇文章報導,免疫療法的引入徹底改變了頭頸癌的治療。這些治療的重點是調節介導腫瘤細胞和 T 淋巴細胞之間相互作用的免疫抑制途徑。2022 年 8 月發表在 Frontiers 上的一篇文章表明,免疫療法具有提供持久抗腫瘤作用的巨大潛力,特別是在治療頭頸部鱗狀細胞癌方面。多種免疫治療方法用於治療頭頸鱗狀細胞癌(HNSCC),包括共刺激激動劑、免疫檢查點抑制劑、抗原疫苗、過繼性T 細胞移植(ACT)、溶瘤病毒治療和EGFR 標靶治療。例如,Merck於2023年11月宣布,FDA批准Merck的抗PD-1療法Keytruda與gemcitabine、cisplatin一起用於治療局部晚期不可切除或轉移性膽道癌(BTC)。
近年來,全球頭頸癌相關的研發活動迅速增加。這種關注度的增加是由於多種因素造成的。例如,全球頭頸癌發生率的上升增加了對預防、早期檢測和治療策略進行更全面研究的需求。包括基因組學和標靶治療在內的醫療技術的進步也為個人化和更有效的治療開闢了新途徑。
例如,2023年10月,處於後期臨床開發的生物技術公司Nanobiotix宣布開始NANORAY-312的患者入組,這是一項測試NBTXR3安全性和有效性的3期臨床試驗。該候選藥物在有效治療老年人頭頸癌方面顯示出巨大潛力。2022 年 9 月,專門從事免疫療法開發和行銷的臨床階段生物技術公司 Genexine Inc. 宣佈在 2 期臨床試驗中開始患者給藥。包括GX-188E(治療性DNA疫苗)、GX-I7(長效白細胞介素7)、OpdivoR(納武單抗)和PD-1免疫檢查點抑制劑在內的三藥聯合療法用於治療轉移性或復發性疾病。頭頸鱗狀細胞癌。
本報告研究和分析了全球頭頸癌市場,提供市場規模和預測、市場動態、主要參與者趨勢和前景等。
Global head and neck cancer market size was valued at USD 2.25 billion in 2023, and is expected to reach USD 3.76 billion in 2031, with a CAGR of 6.62% for the forecast period between 2024 and 2031F. The global head and neck cancer market encompasses a diverse range of treatments and therapies aimed at addressing the complex and challenging landscape of cancers that affect the head and neck regions. The market is experiencing significant growth and evolution as the understanding of the disease and its treatment options continue to advance.
Head and neck cancers, which include tumors in the oral cavity, pharynx, larynx, and other areas, represent a substantial global healthcare burden. Risk factors such as tobacco and alcohol consumption, human papillomavirus (HPV) infection, and environmental factors contribute to the development of these cancers. The global market for head and neck cancer is driven by factors such as increasing incidence rates, improved diagnostic methods, and the development of innovative therapeutic approaches. Recent advancements in immunotherapy and targeted therapies have brought hope to patients. These emerging treatment modalities, along with a growing focus on precision medicine and personalized treatment plans, are transforming the market. Key market players invest in research and development to introduce novel therapies and expand their product portfolios. Moreover, the increasing awareness about the importance of early detection and prevention contributes to market growth. The global head and neck cancer market is dynamic and rapidly evolving, focusing on improving patient outcomes through advanced treatment options and early intervention strategies.
As per an article published by Elsevier, it was reported that the introduction of immunotherapies has brought about a notable transformation in the treatment of head and neck cancer. These therapies are primarily focused on modulating the immunosuppressive pathways that mediate the interaction between tumor cells and T-lymphocytes. An article published in August 2022 by Frontiers highlighted the significant potential of immunotherapies to generate enduring antitumor effects, particularly in the context of treating head and neck squamous cell carcinomas. Various immunotherapy approaches, including the use of costimulatory agonists, immune checkpoint inhibitors, antigenic vaccines, adoptive T cell transfer (ACT), oncolytic virus therapy, and EGFR-targeted therapy, are now being employed for the management of head and neck squamous cell carcinomas (HNSCC). For Instance, Merck declared in November 2023 that the U.S. Food and Drug Administration (FDA) has given the green light to KEYTRUDA, Merck's anti-PD-1 therapy, along with gemcitabine and cisplatin, for addressing individuals dealing with locally advanced unresectable or metastatic biliary tract cancer (BTC).
In recent years, there has been a noticeable surge in research and development activities related to global head and neck cancer. The increased focus can be attributed to several factors, such as the rising incidence of head and neck cancer cases worldwide has spurred the need for more comprehensive research into prevention, early detection, and treatment strategies. Also, advancements in medical technologies, including genomics and targeted therapies, have opened new avenues for personalized and more effective treatments.
For instance, In October 2023, Nanobiotix, a biotechnology company in the later stages of clinical development, announced the initiation of patient enrollment for NANORAY-312, a phase III clinical trial to examine the safety and effectiveness of NBTXR3. The drug candidate has demonstrated significant promise in effectively treating head and neck cancer among elderly patients. In September 2022, Genexine Inc, a biotechnology company in the clinical stage focused on developing and marketing immunotherapies, announcing the initiation of patient dosing in a phase II clinical trial. The company employed a triple combination therapy involving GX-188E (a therapeutic DNA vaccine), GX-I7 (a long-acting interleukin 7), OpdivoR (nivolumab), and PD-1 immune checkpoint inhibitor, for addressing metastatic or recurrent head and neck squamous cell carcinoma.
In the dynamic landscape of global head and neck cancer market, strategic partnerships among key industry players have emerged as pivotal instruments for innovation and progress. These collaborations, characterized by shared expertise and resources, aim to advance research, develop cutting-edge therapies, and improve patient outcomes. Through such alliances, companies combine their strengths in drug development, medical technology, and clinical research to accelerate the discovery and delivery of novel treatments. These partnerships often foster synergies, allowing the pooling of knowledge, technologies, and financial resources. They facilitate the streamlining of regulatory processes and establishing wider access to global markets. Ultimately, these strategic alliances drive the evolution of more effective therapies, early detection methods, and personalized treatment solutions in the fight against head and neck cancers. The collective efforts of these collaborations hold promising potential for shaping the future of cancer care. For Instance, In November 2022, Fulgent Genetics, Inc., a technology-driven genetic testing company situated in the United States, revealed its acquisition of Fulgent Pharma Holdings, Inc. The acquisition aimed to offer a unified solution in the region's fight against head and neck cancer.
Key players in the global head and neck cancer therapeutics market have been strategically focused on several initiatives to enhance treatment outcomes and address unmet medical needs. These initiatives primarily revolve around innovative research and development efforts, collaborative partnerships, and technological advancements. Companies are heavily investing in novel therapies, including immunotherapies and targeted therapies, to improve patient survival rates and reduce adverse effects. Additionally, these players are expanding their product portfolios through mergers, acquisitions, and licensing agreements to broaden their market presence and offer comprehensive solutions. They emphasize personalized medicine approaches, aiming to tailor treatments based on individual patient characteristics. For instance, in April 2023, Eisai initiated the "Made of More" initiative to foster a community for individuals affected by head and neck cancer. Additionally, Eisai is presently conducting trials combining its approved cancer medication, Lenvima, with other oncology drugs for treating head and neck cancers.
The head and neck cancer therapeutics market experienced significant disruption due to the COVID-19 pandemic. The health crisis particularly affected highly immunocompromised cancer patients, leading to strict lockdowns that hindered their access to essential treatments. Additionally, cancer screenings, preventive healthcare services, and elective surgeries were often delayed, except in cases where the benefits outweighed the risks and to prioritize hospital resources for COVID-19 care.
An article published by NCBI (National Center for Biotechnology Information) highlighted that elective surgeries, including head and neck cancer surgeries, were postponed in many countries. Approximately 60% of scheduled outpatient visits at the European Institute of Oncology (IEO) were delayed. The diversion of medical resources to attend COVID-19 patients resulted in a setback for head and neck cancer treatment, leading to increased tumor growth, recurrence, and high mortality rates. As a result, the COVID-19 pandemic significantly impacted the head and neck cancer diagnostics market.
With ongoing research and development, innovative treatments targeting PD-1/PD-L1 pathways have redefined the market. Additionally, companies are emerging with novel therapies, fostering a competitive market. The outlook is promising, emphasizing precision medicine, combination therapies, and biomarker research. Key players are intensifying efforts in clinical trials and strategic collaborations, underscoring a robust drive towards personalized and more effective treatments, potentially transforming the head and neck cancer market.
In August 2022, Genexine Inc, a clinical-stage biotech firm specializing in immunotherapeutics, announced the initiation of patient dosage in a phase II clinical trial. Employing a triple combination therapy comprising GX-188E (a therapeutic DNA vaccine), GX-I7 (a prolonged-acting interleukin 7), and OpdivoR (nivolumab), a PD-1 immune checkpoint inhibitor, the company aimed to treat metastatic head and neck squamous cell carcinoma.
All segments will be provided for all regions and countries covered:
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.