市場調查報告書
商品編碼
1593755
阿片類鎮痛藥市場評估:按產品類型、應用、給藥途徑、分銷管道和地區劃分的機會和預測(2017-2031)Opioid Analgesics Market Assessment, By Product Type, By Application, By Route of Administration, By Distribution Channel, By Region, Opportunities and Forecast, 2017-2031F |
全球阿片類止痛藥市場規模預計將從2023年的452.1億美元成長到2031年的620.2億美元,預測期內複合年增長率為4.03%。
當非鴉片類藥物和物理治療無法有效治療慢性疼痛時,在複方藥物疼痛的預測期內,阿片類止痛藥的市場需求預計將擴大。市面上各種治療方案的快速起效和高效增加了對鴉片類鎮痛藥的需求。
癌症、關節炎、背痛和心臟病等慢性疼痛疾病的盛行率不斷增加,也導致對鴉片類止痛藥物的需求增加。此外,解決阿片類藥物使用安全問題和利用防濫用配方技術的新配方的進步也推動了市場成長。在過去幾年中,藥物濫用已成為一個主要的全球健康議題。隨著用於緩解疼痛的鴉片類藥物處方量顯著增加,濫用率也隨之增加。使用防濫用製劑可以有效控制藥物成癮和處方阿片類藥物過量控制。FDA 正在推動處方阿片類藥物的防濫用製劑 (ADF) 的開發,以解決阿片類藥物濫用問題。
本報告調查了全球阿片類鎮痛藥市場,並提供了市場定義和概述、市場規模趨勢和預測、各個細分市場、地區和主要國家的詳細分析、行業結構以及影響市場增長的因素。主要公司簡介等等。
Global opioid analgesics market is projected to witness a CAGR of 4.03% during the forecast period 2024-2031, growing from USD 45.21 billion in 2023 to USD 62.02 billion in 2031. The market demand for opioid analgesic pharmaceutical products is anticipated to thrive in the forecast period for multimodal pain when non-opioid drugs or physical therapy is ineffective for treating chronic pain issues. The quick onset of action and high efficacy of various treatment options available in the market are increasing the demand for opioid analgesics.
Also, an increase in the prevalence of chronic pain conditions such as cancer, arthritis, and lower back pain, heart disease has led to an increase in demand for opioid analgesics in the market. Advancements in new formulations by resolving safety concerns around the use of opioids and abuse-deterrent formulation technology are boosting the growth of the market. Over the past few years, drug misuse has emerged as a major global health concern. The prescription of opioids for pain relief has increased substantially, and so has the rate of abuse for them. Controlling drug addiction and prescription opioid overdoses can be effectively managed using abuse-deterrent formations. The FDA is pushing for the development of abuse-deterrent formulations (ADFs) for prescription opioids in an effort to address the opioid abuse problem. The government acknowledges that while abuse-deterrent opioids are a step toward potentially less abusive medicines, they are neither abuse nor addiction-proof. For instance, In February 2024, Hikma Pharmaceuticals PLC announced the launch of Fentanyl Citrate Injection, USP 25mcg/0.5mL and 50mcg/mL. As noted by requirements, it is used for anesthesia periods, premedication, induction, and maintenance in the immediate postoperative period. The injection is also used as an adjunct to narcotic analgesia in general or regional anesthesia.
Increasing Prevalence of Cancer to Boost the Market
Chronic pain is present in 20% to 50% of cancer patients. About 80% of advanced-stage cancer patients have moderate to severe pain. One meta-analysis of pooled data from 52 studies found that more than half of the participants reported pain. Cancer pain and pain flares are more likely to occur in younger patients than older patients. Advances in understanding the biological mechanisms of cancer-related pain have led to better-targeted and more effective use of opioids. The global burden of cancer has grown recently, so research into finding new therapies and improving patient outcomes has increased. The increase in the incidence of cancer directly relates to a greater need for pain management strategies that are efficacious. The major driver for the opioid analgesic market is increased research and development initiatives being taken for the treatment of cancer. It is a reality that an increase in knowledge of cancer-related pain is substantially increasing the use of opioid analgesics for pain management. This trend underlines the role of pain relief in cancer care, highlighting a need for providers to balance opioid use with strategies for minimizing misuse and dependence, thus leading to safer and more effective patient care. Researchers are increasingly focusing on developing new therapies and evaluating their efficacy and safety.
Increasing Prevalence of Chronic Pain
The growth of the opioid market is driven by the increasing prevalence of chronic pain, which is affecting millions of individuals globally with the condition such as chronic conditions, including arthritis, fibromyalgia, and neuropathic pain, are increasingly becoming common, and patients are seeking effective pain management solutions to enhance their quality of life. With the increasing prevalence of chronic pain, coupled with an aging population more likely to suffer from this condition, healthcare providers turn to opioids as the first line of treatment. Continued research and development for opioid formulations is also being undertaken to optimize their efficacy with minimal side effects, therefore fueling additional growth in the market. The ongoing development of opioid formulations continues toward improved efficacy but with reduced potential side effects and related dependency risks. These advances address the dual considerations of efficacy and safety in pain relief, patients and providers towards the management of chronic pain with opioids as part of treatment.
In August 2022, Adalvo Limited announced that the company had acquired its first branded product, Onsolis, after finalizing a deal with a leading US-based specialty pharmaceutical company. The brand is an opioid analgesic used in the management of persistent breakthrough pain in cancer patients who are already receiving and tolerant to opioid therapy for their underlying cancer pain. The ongoing development of opioid formulations continues toward improved efficacy but with reduced potential side effects and related dependency risks. These advances address the dual considerations of efficacy and safety in pain relief, nudging patients and providers toward the management of chronic pain with opioids as part of treatment.
Codeine Segment to Dominate the Opioid Analgesics Market
The codeine market is likely to lead in the opioid analgesics market in view of its widespread use and application in clinical conditions for pain management. Codeine is a naturally occurring opioid and is most often preferred as an alternative due to its effective analgesic properties along with relatively lower severity of side effects compared with stronger opioids, making it a popular medicine for the treatment of mild to moderate pain, especially in outpatient settings. In addition, the availability of codeine in several formulations involving combination products with acetaminophen or aspirin makes it more attractive to prescribers and patients. The increasing prevalence of chronic pain disorders and the demand for better pain relief interventions will keep supporting this segment. Continued studies and development of codeine as the best therapeutic agent ensure that the opioid analgesics market will be dominated by codeine. There are several studies that are currently undergoing on Codeine, for instance, the National Superiority Clinical Trial to assess the combination of fixed dosage of Dipyrone and Codeine comparing the isolated use of components in the control of moderate to severe pain after open pelvic-abdominal surgery.
North America Dominates the Opioid Analgesics Market
North America dominates the opioid analgesics markets due to the high prevalence of chronic pain, neuropathic pain, and postoperative surgical pain. Chronic pain is a condition that affects the daily life of many adults in the United States. According to the Centers for Disease Control and Prevention (CDC), almost 21% of the U.S. population, i.e., 51.6 million adults' population, is affected by chronic pain, and 6.9% (17.1 million people) experienced severe chronic pain (i.e., chronic pain that causes significant limitation of daily activities), with a higher prevalence among non-Hispanic American Indians or Alaskans. According to CDC reports that analyzed data from the National Health Interview Survey, chronic pain lasts for at least three months and usually affects the ability to function and work. In contrast, high-impact chronic pain occurs when chronic pain significantly reduces the activities of daily living. Chronic pain is a major public health problem in the United States. The healthcare cost of chronic pain in America is estimated at USD 635 billion per year, according to a JAMA Network Open article.
Future Market Scenario (2024-2031F)
In the opioid analgesic market over the past 10 years, considerable fluctuations have been observed mainly due to the increase in opioid crisis and regulatory control. Nevertheless, future scenarios will be formed through the development of healthcare practice, regulating the framework and achievements in pain management. Pharmaceutical companies are investing in developing abuse-deterrent formulations. These innovations can restore trust between doctors and patients and increase market acceptance. The opioid analgesics market is expected to remain stable, with growth potential in certain areas due to innovation and a growing understanding of pain management. Companies that focus on developing safer opioid formulations and alternative pain management solutions are likely to see growth, which is anticipated to drive the opioid analgesics market. Collaboration with regulators and healthcare providers is key to shaping a responsible future for the opioid analgesics market.
Key Players Landscape and Outlook
The multimodal pain management opioid analgesics market is highly dynamic, with several players like Pfizer Inc., Johnson & Johnson Services, Inc., Teva Pharmaceuticals Industries Ltd., Endo Pharmaceuticals Inc., Sun Pharmaceuticals Industries Ltd., Bayer AG, Abbott Laboratories, Purdue Pharma L.P., Hikma Pharmaceuticals PLC., Sanofi S.A. Corporation Opioid Analgesics. Significant market activities have been reported in recent times, including distribution agreements and acquisitions alongside several product launches. In May 2023 Trevena Inc. a biopharmaceutical company, announced that its partner, Jiangsu Nhwa Pharmaceutical Co., Ltd., a China-based pharmaceutical company, has received approval from China's National Medical Products Administration (NMPA) for Olinvyk (oliceridine). Olinvyk is an opioid agonist indicated to manage pain severe enough to require an intravenous opioid analgesic in adult patients whose alternative treatments are inadequate.
In April 2023, Rusan Pharma Ltd. submitted a proposal to the commission for approval to manufacture and market methadone oral solution 1 mg/ml, as well as an application for a BA/BE research and clinical trial exemption. Methadone oral solution 1 mg/ml is already approved product. But this firm is required to submit BA/BE study protocol for further review by the committee.
All segments will be provided for all regions and countries covered
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.