市場調查報告書
商品編碼
1593762
全球骨質疏鬆症治療市場評估:依藥物類型、藥物類別、給藥途徑、通路、地區、機會、預測(2017-2031)Osteoporosis Treatment Market Assessment, By Drug Type, By Drug Class, By Route of Administration, By Distribution Channel, By Region, Opportunities and Forecast, 2017-2031F |
全球骨質疏鬆症治療市場規模預計將從 2023 年的 147.9 億美元增至 2031 年的 214.4 億美元,預計 2024-2031 年的複合年增長率為 4.75%。由於骨質疏鬆症治療帶來的疾病負擔不斷增加、人口老化以及該領域持續的藥物開發和審批活動,預計該市場將繼續增長。
骨質疏鬆症是一種骨病,其特徵是骨密度降低和骨折風險增加。治療方法包括改變生活方式(飲食、運動)、藥物(雙磷酸鹽、荷爾蒙治療、單株抗體)和補充劑(鈣、維生素等)以強化骨骼並降低骨折風險D)等。由於全球骨質疏鬆患者數量不斷增加以及骨質疏鬆患者治療選擇的改善,預計該市場將會成長。政府和其他利害關係人的多項措施進一步提高了市場成長率。近年來,將藥物治療與營養、運動等生活方式改善相結合的個人化醫療引起了人們的關注。藥物傳輸系統的創新和對新治療劑的持續研究預計將進一步推動市場成長。治療依從性和副作用等課題仍然存在,凸顯了持續對患者進行教育和支持的必要性。在人口變化以及醫學研究和技術進步的推動下,該市場預計將增長。
例如,2024 年 8 月,倫敦國家健康與照護卓越研究所 (NICE) 推薦阿巴洛帕肽作為停經後女性骨質疏鬆症的新治療選擇,這些女性骨折風險極高。該藥物由 Theramex HQ UK Limited 銷售,商品名為 Eladynos,透過促進骨形成來增加骨密度。當標準治療無反應或不耐受時,它被用作替代藥物。
本報告研究和分析了全球骨質疏鬆症治療市場,提供市場規模和預測、市場動態以及主要參與者的狀況。
Global osteoporosis treatment market is projected to witness a CAGR of 4.75% during the forecast period 2024-2031, growing from USD 14.79 billion in 2023 to USD 21.44 billion in 2031. The osteoporosis treatment market is poised for future growth due to the increasing disease burden of osteoporosis treatment, the aging population, and ongoing drug development and approval activities in the field.
Osteoporosis is a bone disease characterized by decreased bone density and increased fracture risk. Treatment approaches include lifestyle modifications (diet, exercise), medications (bisphosphonates, hormone therapies, and monoclonal antibodies), and supplements (calcium, vitamin D) to strengthen bones and reduce fracture risk. The market for osteoporosis drugs is anticipated to thrive under the influence of rising osteoporosis cases globally and improved treatment options available for osteoporotic patients. Several initiatives from the government and other stakeholders further strengthen the growth rate in the market. Recent trends include a focus on personalized medicine, combining pharmacological treatments with lifestyle modifications like nutrition and exercise. Innovations in drug delivery systems and ongoing research into new therapeutic agents are expected to enhance market growth further. Challenges such as treatment adherence and side effects persist, underscoring the need for ongoing patient education and support. The osteoporosis treatment market is poised for growth, fueled by demographic shifts and advancements in medical research and technology.
For instance, in August 2024, the National Institute for Health and Care Excellence (NICE), London, recommended abaloparatide as a new treatment option for osteoporosis in postmenopausal women at very high fracture risk, benefiting over 14,000 individuals. This drug, marketed as Eladynos by Theramex HQ UK Limited, enhances bone density by stimulating bone formation. It serves as an alternative for those who do not respond to or tolerate standard treatments.
Rising Prevalence of Osteoporosis and Improved Treatment Options to Boost Market Demand
The major driving factor of the osteoporosis treatment market has been the increase in the incidence of the disease among the elderly. The greater recognition of the condition has led to more patients seeking effective therapy to prevent fractures and allow the bones to become healthy again. In addition, improved treatment options, such as the introduction of bisphosphonates, hormone therapies, and newer biologics, reinforce the increased demand for these products. More attention from healthcare providers and organizations toward early diagnosis and preventive care is motivating patients to seek treatment. Personalized medicine further increases the appeal of osteoporosis therapies that are treated uniquely for every patient. With the increasing number of the aging population and the related risk of osteoporosis, the treatment for osteoporosis has become a rapidly growing and potential market. With the rising emphasis on bone health, the promising area for effective and innovative osteoporotic therapy will increase even further, pointing out the clear priority for pharmaceutical companies. According to the International Osteoporosis Foundation, osteoporosis affects approximately 6.3% of men over the age of 50 and 21.2% of women over the same age range globally, and 37 million fragility fractures occur annually in osteoporosis patients aged over 55.
Government Initiatives for Osteoporosis Treatment Drive Market Growth
Government-led programs and policies support the osteoporosis treatment market growth. Public health education programs enhance awareness about disease and its risk factors. A variety of updated guidelines on routine screening that facilitate early diagnosis and timely interventions for postmenopausal women and older adults further boost the demand for treatment. Furthermore, public funding for research on the disease also pushes the discovery of novel treatments and developments in existing treatments, encouraging pharmaceutical firms to invest in this area. Coordination between government health departments and healthcare providers will be improved education and training, improving the treatment of osteoporosis, and patient compliance with treatment. Improved policies that increase reimbursement for the treatment of osteoporosis enhance access to care and encourage more patients to seek care. For instance, in July 2024, The Centers for Medicare & Medicaid Services (CMS) proposed a 2025 Physician Fee Schedule aimed at enhancing post-fracture care for the 10 million Americans with osteoporosis. This initiative, supported by various health organizations, seeks to incentivize better care and reduce the rising costs associated with osteoporotic fractures, projected to reach USD 95 billion by 2040. Key changes include new coding for fracture management and a call for public comment to improve evidence-based care access, particularly for disproportionately affected women.
Bisphosphonate Segment to Dominate Market
The bisphosphonate class of drugs is anticipated to dominate the osteoporosis treatment market because drugs like alendronate and risedronate have proven to have an established efficacy in reducing fracture risk and, therefore, are trusted by clinicians. Other bisphosphonates are also available as generic equivalents, making them more accessible and adaptable. More often, bisphosphonates are highly regulated under clinical guidelines, and therefore, their regulated use among healthcare providers is ensured. They also tend to have a more benign safety profile compared with other newer treatments, together with a longer duration of action that permits less frequent dosing, thereby improving compliance in the patient. Ongoing studies concerning their long-term effect also help to support their clinical use further and thus remain an integral part of treatment protocols.
For instance, in March 2024, Sandoz Group AG received FDA approval for two biosimilars, Jubbonti and Wyost, targeting Amgen Inc.'s denosumab, a key treatment for osteoporosis. Jubbonti will compete with Prolia, aimed at high-risk osteoporotic men and postmenopausal women, and is also indicated for glucocorticoid-induced osteoporosis. Wyost will challenge Xgeva, which is used to prevent skeletal-related events in cancer patients. Both biosimilars have interchangeable status, allowing easy substitution without prescription changes. While this development promises improved access to essential osteoporosis treatments, Sandoz has not disclosed launch dates or pricing due to ongoing patent litigation.
North America Dominates Osteoporosis Treatment Market
The North America osteoporosis treatment market is important, as the population in this market is more aged, which leads to a greater incidence of osteoporosis and related fractures. Moreover, increased awareness of the disease by healthcare providers and patients has led to increased testing, evaluation, and treatment, which has driven this burgeoning market. Advances in healthcare infrastructure in the region provide easy access to the latest medical technologies, thus making the development and distribution of effective treatments for osteoporosis easier. Insurance coverage and reimbursement policies are other key factors driving the market. Some health insurance covers osteoporosis medications for many patients, hence increasing adherence to the treatment. Regulatory agencies, like the USFDA, ensure new therapies are placed under an adequate check, ensuring more confidence in treatment safety and efficacy.
For instance, in February 2024, the USFDA added a Boxed Warning to Prolia (denosumab), indicating an increased risk of severe hypocalcemia in patients with advanced chronic kidney disease (CKD), particularly those on dialysis. This risk is heightened in patients with CKD-mineral and bone disorders. The warning aims to ensure proper patient selection and monitoring, as severe hypocalcemia can lead to serious health complications, including hospitalization and death.
Future Market Scenario (2024-2031F)
Bone-targeting nanoparticles represent a groundbreaking advancement in the treatment of osteoporosis by increasing drug delivery specifically to bone tissue. Traditional osteoporosis medications often suffer from low targeting specificity, leading to systemic toxicity and reduced efficacy. In contrast, these nanoparticles can be engineered to recognize and bind to bone tissue, ensuring that therapeutic agents are delivered precisely where needed. The nanoparticles can encapsulate various therapeutic agents, including growth factors and nucleic acids, improving their bioavailability and stability. Their small size allows for better penetration into biological barriers, while modifications can enhance their affinity for bone surfaces. For instance, lipid nanocarriers and exosomes have shown promise in delivering anti-osteoporotic agents directly to osteoblasts, promoting bone formation and inhibiting osteoclast activity. This targeted approach minimizes side effects and maximizes therapeutic outcomes, paving the way for more effective osteoporosis treatments in the future.
Key Players Landscape and Outlook
Global pharmaceutical giants like Pfizer, Inc., Novartis AG, and many more mainly dominate the market for osteoporosis treatment. The drugs used for osteoporosis include branded and generic versions, and smaller market players cater the generic equivalents. Recent market activities include regulatory approvals and recommendations, along with acquisitions.
In July 2024, Bone Health Technologies, Inc. (BHT) acquired Wellen, a Brooklyn-based company specializing in personalized exercise programs for osteoporosis in women over 50. This acquisition aims to enhance BHT's offerings by integrating Wellen's expertise with BHT's upcoming Osteoboost vibration therapy belt, set to launch in late 2024. The combined approach seeks to provide effective, non-drug solutions for osteoporosis and osteopenia, addressing a significant public health issue affecting millions globally.
All segments will be provided for all regions and countries covered
Companies mentioned above DO NOT hold any order as per market share and can be changed as per information available during research work.