市場調查報告書
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1380387
全球一次性生物加工市場 2023-2030Global Single-Use Bioprocessing Market 2023-2030 |
全球一次性生物加工市場預計在預測期內(2023-2030)將以 10.9% 的CAGR成長。一次性生物加工技術廣泛用於生物製藥應用,包括過濾、混合、純化、上游表達、儲存和分離。一次性生物反應器的日益普及加上先進技術是支持全球市場成長的關鍵因素。一次性生物反應器的優點是它們為製造商提供了靈活性。停機的主要原因之一是在上游過程中準備生物反應器。一次性生物反應器大大減少了為後續批次準備生物反應器所花費的時間。因此,市場參與者也專注於引入大型一次性生物反應器生物加工解決方案,以進一步促進市場成長。例如,2021年2月,擁有開放取得生物製劑技術平台的全球公司藥明生物宣布,其位於中國的MFG5原料藥(DS)生產設施已成功啟動GMP營運,產能為36,000L,部署了9台4,000 L一次性生物反應器。
全球一次性生物加工市場按產品、應用和最終用戶進行細分。根據產品,市場細分為過濾組件、介質袋和容器、一次性生物反應器、一次性混合器和其他(一次性濾筒)。根據應用,市場細分為過濾、細胞培養、純化和其他(混合)。此外,根據最終用戶,市場細分為生物製藥製造商、學術和臨床研究機構及其他機構(CRO、CMO)。在這些應用中,由於先進的一次性過濾系統的發展不斷增加,過濾子細分市場預計將佔據相當大的市場佔有率。一次性過濾系統由許多完全一次性的組件組成,包括整個流體路徑和過濾器。這樣可以輕鬆快速地適應不斷變化的要求 - 無論是需要不同的過濾孔徑還是增加或減少填充量。
在這些產品中,介質袋和容器細分市場預計將在全球一次性生物加工市場中佔據相當大的佔有率。該細分市場的成長歸因於一次性生物加工技術的使用不斷增加,該技術與傳統不銹鋼系統相比具有多種優勢,包括減少清潔和驗證時間、提高靈活性以及降低交叉污染的風險。各公司在不同一次性容器和組件在關鍵製程步驟(例如保護、填充和排水、冷凍和解凍、原料藥的儲存和運輸)中的行為方面擁有豐富的專業知識,這些知識轉化為一次性袋子。例如,2022 年 10 月,Single Use Support GmbH 正在擴大其產品組合,推出 IRIS 品牌的新型一次性生物程序容器。該公司在生物製藥流體管理領域提供可靠的製程解決方案,並繼續追求與供應商無關的方法。
全球一次性生物加工市場根據地理位置進一步細分,包括北美(美國和加拿大)、歐洲(英國、義大利、西班牙、德國、法國和歐洲其他地區)、亞太地區(印度、中國) 、日本、韓國和亞洲其他地區)以及世界其他地區(中東和非洲以及拉丁美洲)。其中,亞太地區預計將在全球市場中佔據顯著佔有率,因為在基因療法快速成長的推動下,採用一次性技術進行病毒載體和基因療法生產的勢頭正在增強。主要市場參與者包括Foxx Life Sciences Pvt. Ltd.、Cesco Bioengineering Co. Ltd.、 PharmNXT 生物技術及其他
在所有地區中,北美地區預計在預測期內將以相當大的CAGR成長。區域成長歸因於對一次性生物加工設備的需求增加,這也是由於越來越重視疫苗生產以幫助該地區的疾病預防措施所推動的。用於各種生物製藥應用的一次性生物加工技術推動了市場的成長。一次性生物加工技術的採用受到其所提供的引人注目的優勢的推動,包括降低交叉污染的風險、簡化的轉換流程和更快的周轉時間。此外,聚合物材料的進步促進了一次性生物反應器的發展,其細胞培養性能與不銹鋼反應器相當,進一步推動了市場擴張。此外,北美生物製程系統聯盟(BPSA)的存在旨在推動一次性技術的採用,預計將進一步推動該地區一次性系統的銷售。
此外,合約服務提供者對在北美發展基地的興趣日益濃厚,加上 CMO 中採用一次性設備的趨勢,成為本地和全球公司持續投資的催化劑。主要市場參與者包括 Agilitech Group、Avantor, Inc.、Corning Inc.、Entegris, Inc.、Pall Corp.、Thermo Fisher Scientific Inc. 等
Title: Global Single-Use Bioprocessing Market Size, Share & Trends Analysis Report by Product (Filtration Assemblies, Media Bags and Containers, Disposable Bioreactors, Disposable Mixers and Other), by Application (Filtration, Cell Culture, Purification and Other), and by End Users (Biopharmaceutical Manufacturers, Academic and Clinical Research Institutes and Other),Forecast Period (2023-2030).
The global single-use bioprocessing market is anticipated to grow at a CAGR of 10.9% during the Forecast Period (2023-2030). Single-use bioprocessing technology is used in a broad range of biopharmaceutical applications, including filtration, mixing, purification, upstream expression, storage, and separation. The growing adoption of single use bioreactor coupled with advance technology is the key factor supporting the growth of the market globally. The advantage of single-use bioreactors is the flexibility they allow manufacturers. One of the main culprits in downtime is preparing the bioreactor in the upstream process. Single-use bioreactors drastically decrease the time spent preparing the bioreactor for the subsequent batch. Hence, the market players are also focusing on introducing large single-use bioreactors bioprocessing solutions that further bolster the market growth. For instance, in February 2021, WuXi Biologics a global company with open-access biologics technology platforms, announced that its MFG5 Drug Substance (DS) manufacturing facility in China has successfully launched GMP operation, with a capacity of 36,000L, deploying nine 4,000L single-use bioreactors.
The global single-use bioprocessing market is segmented on the product, application, and end users. Based on the product, the market is sub-segmented into filtration assemblies, media bags and containers, disposable bioreactors, disposable mixers and others (disposable filter cartridges). Based on the application, the market is sub-segmented into filtration, cell culture, purification and other (mixing). Further, on the basis of end users, the market is sub-segmented into biopharmaceutical manufacturers, academic and clinical research institutes and others (CROs, CMOs). Among the applications, the filtration sub-segment is anticipated to hold a considerable share of the market owing to the rise in the development of advanced Single-use filtration systems are comprised of a number of fully disposable components, including the entire fluid pathway and filters. This allows for easy and quick adaptation to changing requirements - be it the need for different filter pore sizes or an increased or decreased filling volume.
Among the products, the media bags and containers sub-segment is expected to hold a considerable share of the global single-use bioprocessing market. The segmental growth is attributed to the growing uses of single-use bioprocessing technologies that offer several advantages over traditional stainless-steel systems, including reduced cleaning and validation time, increased flexibility, and reduced risk of cross-contamination. Various companies' extensive expertise in the behavior of different single-use containers and assemblies in critical process steps, such as protection, filling & draining, freezing & thawing, storage and shipping of drug substances, that translated into single-use bags. For instance, in October 2022, Single Use Support GmbH is expanding its product portfolio with new single-use bioprocess containers under the brand name IRIS. The company provide reliable process solutions in the field of biopharmaceutical fluid management, continuing to pursue its vendor-agnostic approach.
The global single-use bioprocessing market is further segmented based on geography including North America (the US, and Canada), Europe (UK, Italy, Spain, Germany, France, and the Rest of Europe), Asia-Pacific (India, China, Japan, South Korea, and Rest of Asia), and the Rest of the World (the Middle East & Africa, and Latin America. Among these, Asia-Pacific is anticipated to hold a prominent share of the market across the globe, owing to the adoption of single-use technologies for viral vector and gene therapy production is gaining momentum, driven by the rapid growth of gene-based therapeutics. The key market players include Foxx Life Sciences Pvt. Ltd., Cesco Bioengineering Co. Ltd., PharmNXT Biotech and others
Among all regions, the North America regions is anticipated to grow at a considerable CAGR over the forecast period. Regional growth is attributed to an increase in demand for single-use bioprocessing equipment is also driven by an increasing focus on vaccine production to aid in disease prevention measures in the region. single-use bioprocessing technologies for various biopharmaceutical applications have propelled the growth of the market. The adoption of single-use bioprocessing technologies is propelled by the compelling benefits they offer, including reduced risk of cross-contamination, streamlined changeover processes, and faster turnaround times. Additionally, advancements in polymer materials have led to the development of single-use bioreactors that offer cell culture performance at par with stainless steel reactors, further fueling market expansion. Moreover, the presence of the Bio-process System Alliance (BPSA) in North America, that aims at advancing the adoption of single-use technologies, is expected to further drive the sales of disposable systems in the region.
Furthermore, the increasing interest of contract service providers to develop their base in North America, coupled with the trend of implementation of disposables in CMOs, acts as a catalyst for continued investments by local as well as global companies. The key market players include Agilitech Group, Avantor, Inc., Corning Inc., Entegris, Inc., Pall Corp., Thermo Fisher Scientific Inc. and others
The major companies serving the single-use bioprocessing market include: Corning Inc., Eppendorf AG, Merck KGaA, Sartorius AG, Thermo Fisher Scientific Inc. and others. The market players are considerably contributing to the market growth by the adoption of various strategies including mergers and acquisitions, partnerships, collaborations, funding, and new product launches, to stay competitive in the market. For instance, in January 2020, 3i Group plc launched a single-use bioprocessing platform serving the biopharmaceutical sector with the acquisitions of Cellon, Silicone Altimex and TBL Performance Plastics. The company offer industry products, such as the PharmaTainerTM bottles and carboy product line, aSURE® fittings, Tri-Clamp® ends, Bio-EaseTM clamps, and a wide range of tubing solutions.