Product Code: PM1782
The global organoids and spheroids market size is expected to reach USD 5,117.59 million by 2032, according to a new study by Polaris Market Research. The report "Organoids and Spheroids Market Share, Size, Trends, Industry Analysis Report - By Type, Application, End Use, and Region; Segment Forecasts, 2024-2032" gives a detailed insight into current market dynamics and provides analysis on future market growth.
The development of genetic editing techniques such as CRISPR/Cas-9 has enabled researchers to make precise changes to genes in stem cells, leading to the creation of organoids and spheroids that replicate disease conditions. These advancements have provided researchers with improved models for studying diseases and testing drugs, yielding valuable insights into complex cellular conditions. The combination of progress in stem cell technology and 3D culture methods has played a crucial role in the steady growth of the organoids and spheroids market. In January 2024, USC researchers developed a new human brain organoid model to study cerebellum development and the emergence of cerebellar pathology in neurological disease.
Patient-specific organoids represent a robust platform for advancing personalized medicine and driving the growth of the organoids and spheroids market by enabling the testing of potential drugs on tissues sourced from patients, which provides valuable insights into individual therapy responses. The clinical importance of organoids and spheroids in both research and clinical practice is crucial for developing personalized organoid models and furthering the progress of P4 medicine.
The development of 3D bioprinting technologies and organ-on-a-chip platforms significantly advances organoid and spheroid research. 3D bioprinting enables the creation of complex, customized tissue models with high precision, enhancing drug testing and personalized medicine. Organ-on-a-chip platforms replicate organ functions in miniature, allowing for dynamic modeling, high-throughput screening, and personalized treatment strategies. Together, these innovations improve the accuracy and relevance of biomedical research, facilitating more effective drug development and disease understanding.
Organoids and Spheroids Market Report Highlights
Based on type, the spheroids segment held a larger share in 2023, owing to their significant use in drug discovery and disease modeling.
The organoids segment is projected to grow rapidly during the forecast period, fueled by rising occurrences of diseases such as cancer, neurodegenerative disorders, and infectious diseases, driving demand for advanced research models.
By application, the developmental biology segment dominated the market in 2023, owing to its application in the mechanism of organogenesis.
North America holds the largest share in 2023, owing to the rising use of organoids and spheroids for personalized medicine.
A few key players are 3D Biomatrix, 3D Biotek, AMS Biotechnology, Cellesce, Greiner Bio-One, and Thermo Fisher Scientific.
Polaris Market Research has segmented the organoids and spheroids market report on the basis of type, application, end use, and region:
By Type Outlook (Revenue - USD million, 2019-2032)
- Organoids
- By Type
- Neural Organoids
- Hepatic Organoids
- Intestinal Organoids
- Other Organoids
- By Method
- General Submerged Method for Organoid Culture
- Crypt Organoid Culture Techniques
- Air Liquid Interface (ALI) Method for Organoid Culture
- Clonal Organoids from Lgr5+ Cells
- Brain and Retina Organoid Formation Protocol
- Others
- By Source
- Primary Tissues
- Stem Cells
- Spheroids
- By Type
- Multicellular Tumor Spheroids (MCTS)
- Neurospheres
- Mammospheres
- Hepatospheres
- Embryoid Bodies
- By Method
- Micropatterned Plates
- Low Cell Attachment Plates
- Hanging Drop Method
- Others
- By Source
- Cell Line
- Primary Cell
- iPSCs Derived Cells
By Application Outlook (Revenue - USD million, 2019-2032)
- Developmental Biology
- Personalized Medicine
- Regenerative Medicine
- Disease Pathology Studies
- Drug Toxicity & Efficacy Testing
By End Use Outlook (Revenue - USD million, 2019-2032)
- Biotechnology & Pharmaceutical Industries
- Academic & Research Institutes
- Hospitals & Diagnostic Centers
By Regional Outlook (Revenue - USD million, 2019-2032)
- North America
- US
- Canada
- Europe
- Germany
- France
- UK
- Italy
- Spain
- Netherlands
- Russia
- Rest of Europe
- Asia Pacific
- China
- Japan
- India
- Malaysia
- South Korea
- Indonesia
- Australia
- Rest of Asia Pacific
- Middle East & Africa
- Saudi Arabia
- UAE
- Israel
- South Africa
- Rest of Middle East & Africa
- Latin America
- Mexico
- Brazil
- Argentina
- Rest of Latin America
Table of Contents
1. Introduction
- 1.1. Report Description
- 1.1.1. Objectives of the Study
- 1.1.2. Market Scope
- 1.1.3. Assumptions
- 1.2. Stakeholders
2. Executive Summary
3. Research Methodology
- 3.1. Overview
- 3.2. Data Sources
- 3.2.1. Primary Sources
- 3.2.2. Secondary Sources
4. Global Organoids and Spheroids Market Insights
- 4.1. Organoids and Spheroids Market - Market Snapshot
- 4.2. Organoids and Spheroids Market Dynamics
- 4.2.1. Drivers and Opportunities
- 4.2.1.1. Advancement in stem cell research
- 4.2.1.2. Increased application in drug discovery and personalized medicine
- 4.2.2. Restraints and Challenges
- 4.2.2.1. High cost of development and Production
- 4.3. Porter's Five Forces Analysis
- 4.3.1. Bargaining Power of Suppliers (Moderate)
- 4.3.2. Threats of New Entrants: (Low)
- 4.3.3. Bargaining Power of Buyers (Moderate)
- 4.3.4. Threat of Substitute (Moderate)
- 4.3.5. Rivalry among existing firms (High)
- 4.4. PESTEL Analysis
- 4.5. Organoids and Spheroids Market Application Trends
- 4.6. Value Chain Analysis
- 4.7. COVID-19 Impact Analysis
5. Global Organoids and Spheroids Market, by Type
- 5.1. Key Findings
- 5.2. Introduction
- 5.2.1. Global Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 5.3. Organoids
- 5.3.1. Global Organoids and Spheroids Market, by Organoids, by Region, 2019-2032 (USD Million)
- 5.4. Spheroids
- 5.4.1. Global Organoids and Spheroids Market, by Spheroids, by Region, 2019-2032 (USD Million)
6. Global Organoids and Spheroids Market, by Application
- 6.1. Key Findings
- 6.2. Introduction
- 6.2.1. Global Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 6.3. Developmental Biology
- 6.3.1. Global Organoids and Spheroids Market, by Developmental Biology, by Region, 2019-2032 (USD Million)
- 6.4. Personalized Medicine
- 6.4.1. Global Organoids and Spheroids Market, by Personalized Medicine, by Region, 2019-2032 (USD Million)
- 6.5. Regenerative Medicine
- 6.5.1. Global Organoids and Spheroids Market, by Regenerative Medicine, by Region, 2019-2032 (USD Million)
- 6.6. Disease Pathology Studies
- 6.6.1. Global Organoids and Spheroids Market, by Disease Pathology Studies, by Region, 2019-2032 (USD Million)
- 6.7. Drug Toxicity & Efficacy Testing
- 6.7.1. Global Organoids and Spheroids Market, by Drug Toxicity & Efficacy Testing, by Region, 2019-2032 (USD Million)
7. Global Organoids and Spheroids Market, by End Use
- 7.1. Key Findings
- 7.2. Introduction
- 7.2.1. Global Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 7.3. Biotechnology & Pharmaceutical Industries
- 7.3.1. Global Organoids and Spheroids Market, by Biotechnology & Pharmaceutical Industries, by Region, 2019-2032 (USD Million)
- 7.4. Academic & Research Institutes
- 7.4.1. Global Organoids and Spheroids Market, by Academic & Research Institutes, by Region, 2019-2032 (USD Million)
- 7.5. Hospitals & Diagnostic Centers
- 7.5.1. Global Organoids and Spheroids Market, by Hospitals & Diagnostic Centers, by Region, 2019-2032 (USD Million)
8. Global Organoids and Spheroids Market, by Geography
- 8.1. Key Findings
- 8.2. Introduction
- 8.2.1. Organoids and Spheroids Market Assessment, By Geography, 2019-2032 (USD Million)
- 8.3. Organoids and Spheroids Market - North America
- 8.3.1. North America: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.3.2. North America: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.3.3. North America: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.3.4. Organoids and Spheroids Market - U.S.
- 8.3.4.1. U.S.: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.3.4.2. U.S.: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.3.4.3. U.S.: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.3.5. Organoids and Spheroids Market - Canada
- 8.3.5.1. Canada: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.3.5.2. Canada: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.3.5.3. Canada: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.4. Organoids and Spheroids Market - Europe
- 8.4.1. Europe: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.4.2. Europe: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.4.3. Europe: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.4.4. Organoids and Spheroids Market - UK
- 8.4.4.1. UK: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.4.4.2. UK: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.4.4.3. UK: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.4.5. Organoids and Spheroids Market - France
- 8.4.5.1. France: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.4.5.2. France: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.4.5.3. France: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.4.6. Organoids and Spheroids Market - Germany
- 8.4.6.1. Germany: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.4.6.2. Germany: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.4.6.3. Germany: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.4.7. Organoids and Spheroids Market - Italy
- 8.4.7.1. Italy: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.4.7.2. Italy: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.4.7.3. Italy: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.4.8. Organoids and Spheroids Market - Spain
- 8.4.8.1. Spain: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.4.8.2. Spain: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.4.8.3. Spain: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.4.9. Organoids and Spheroids Market - Netherlands
- 8.4.9.1. Netherlands: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.4.9.2. Netherlands: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.4.9.3. Netherlands: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.4.10. Organoids and Spheroids Market - Russia
- 8.4.10.1. Russia: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.4.10.2. Russia: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.4.10.3. Russia: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.4.11. Organoids and Spheroids Market - Rest of Europe
- 8.4.11.1. Rest of Europe: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.4.11.2. Rest of Europe: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.4.11.3. Rest of Europe: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.5. Organoids and Spheroids Market - Asia Pacific
- 8.5.1. Asia Pacific: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.5.2. Asia Pacific: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.5.3. Asia Pacific: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.5.4. Organoids and Spheroids Market - China
- 8.5.4.1. China: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.5.4.2. China: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.5.4.3. China: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.5.5. Organoids and Spheroids Market - India
- 8.5.5.1. India: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.5.5.2. India: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.5.5.3. India: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.5.6. Organoids and Spheroids Market - Malaysia
- 8.5.6.1. Malaysia: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.5.6.2. Malaysia: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.5.6.3. Malaysia: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.5.7. Organoids and Spheroids Market - Japan
- 8.5.7.1. Japan: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.5.7.2. Japan: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.5.7.3. Japan: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.5.8. Organoids and Spheroids Market - Indonesia
- 8.5.8.1. Indonesia: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.5.8.2. Indonesia: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.5.8.3. Indonesia: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.5.9. Organoids and Spheroids Market - South Korea
- 8.5.9.1. South Korea: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.5.9.2. South Korea: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.5.9.3. South Korea: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.5.10. Organoids and Spheroids Market - Australia
- 8.5.10.1. Australia: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.5.10.2. Australia: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.5.10.3. Australia: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.5.11. Organoids and Spheroids Market - Rest of Asia Pacific
- 8.5.11.1. Rest of Asia Pacific: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.5.11.2. Rest of Asia Pacific: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.5.11.3. Rest of Asia Pacific: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.6. Organoids and Spheroids Market - Middle East & Africa
- 8.6.1. Middle East & Africa: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.6.2. Middle East & Africa: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.6.3. Middle East & Africa: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.6.4. Organoids and Spheroids Market - Saudi Arabia
- 8.6.4.1. Saudi Arabia: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.6.4.2. Saudi Arabia: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.6.4.3. Saudi Arabia: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.6.5. Organoids and Spheroids Market - UAE
- 8.6.5.1. UAE: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.6.5.2. UAE: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.6.5.3. UAE: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.6.6. Organoids and Spheroids Market - Israel
- 8.6.6.1. Israel: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.6.6.2. Israel: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.6.6.3. Israel: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.6.7. Organoids and Spheroids Market - South Africa
- 8.6.7.1. South Africa: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.6.7.2. South Africa: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.6.7.3. South Africa: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.6.8. Organoids and Spheroids Market - Rest of Middle East & Africa
- 8.6.8.1. Rest of Middle East & Africa: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.6.8.2. Rest of Middle East & Africa: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.6.8.3. Rest of Middle East & Africa: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.7. Organoids and Spheroids Market - Latin America
- 8.7.1. Latin America: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.7.2. Latin America: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.7.3. Latin America: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.7.4. Organoids and Spheroids Market - Mexico
- 8.7.4.1. Mexico: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.7.4.2. Mexico: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.7.4.3. Mexico: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.7.5. Organoids and Spheroids Market - Brazil
- 8.7.5.1. Brazil: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.7.5.2. Brazil: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.7.5.3. Brazil: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.7.6. Organoids and Spheroids Market - Argentina
- 8.7.6.1. Argentina: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.7.6.2. Argentina: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.7.6.3. Argentina: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
- 8.7.7. Organoids and Spheroids Market - Rest of Latin America
- 8.7.7.1. Rest of Latin America: Organoids and Spheroids Market, by Type, 2019-2032 (USD Million)
- 8.7.7.2. Rest of Latin America: Organoids and Spheroids Market, by Application, 2019-2032 (USD Million)
- 8.7.7.3. Rest of Latin America: Organoids and Spheroids Market, by End Use, 2019-2032 (USD Million)
9. Competitive Landscape
- 9.1. Expansion and Acquisition Analysis
- 9.1.1. Expansion
- 9.1.2. Acquisitions
- 9.2. Partnerships/Collaborations/Agreements/Exhibitions
10. Company Profiles
- 10.1. 3D Biomatrix
- 10.1.1. Company Overview
- 10.1.2. Financial Performance
- 10.1.3. Type Benchmarking
- 10.1.4. Recent Development
- 10.2. 3D Biotek LLC
- 10.2.1. Company Overview
- 10.2.2. Financial Performance
- 10.2.3. Type Benchmarking
- 10.2.4. Recent Development
- 10.3. AMS Biotechnology Limited
- 10.3.1. Company Overview
- 10.3.2. Financial Performance
- 10.3.3. Type Benchmarking
- 10.3.4. Recent Development
- 10.4. Cellesce Ltd.
- 10.4.1. Company Overview
- 10.4.2. Financial Performance
- 10.4.3. Type Benchmarking
- 10.4.4. Recent Development
- 10.5. TheWell Bioscience
- 10.5.1. Company Overview
- 10.5.2. Financial Performance
- 10.5.3. Type Benchmarking
- 10.5.4. Recent Development
- 10.6. Greiner Bio-One
- 10.6.1. Company Overview
- 10.6.2. Financial Performance
- 10.6.3. Type Benchmarking
- 10.6.4. Recent Development
- 10.7. Hubrecht Organoid Technology (HUB)
- 10.7.1. Company Overview
- 10.7.2. Financial Performance
- 10.7.3. Type Benchmarking
- 10.7.4. Recent Development
- 10.8. InSphero
- 10.8.1. Company Overview
- 10.8.2. Financial Performance
- 10.8.3. Type Benchmarking
- 10.8.4. Recent Development
- 10.9. Lonza
- 10.9.1. Company Overview
- 10.9.2. Financial Performance
- 10.9.3. Type Benchmarking
- 10.9.4. Recent Development
- 10.10. Merck KGaA
- 10.10.1. Company Overview
- 10.10.2. Financial Performance
- 10.10.3. Type Benchmarking
- 10.10.4. Recent Development
- 10.11. Prellis Biologics
- 10.11.1. Company Overview
- 10.11.2. Financial Performance
- 10.11.3. Type Benchmarking
- 10.11.4. Recent Development
- 10.12. STEMCELL Technologies Inc.
- 10.12.1. Company Overview
- 10.12.2. Financial Performance
- 10.12.3. Type Benchmarking
- 10.12.4. Recent Development
- 10.13. Thermo Fisher Scientific, Inc.
- 10.13.1. Company Overview
- 10.13.2. Financial Performance
- 10.13.3. Type Benchmarking
- 10.13.4. Recent Development