市場調查報告書
商品編碼
1625427
CAR-T細胞療法市場,規模,佔有率,趨勢,產業分析報告:各適應症,標的抗原,各地區 - 市場預測,2025年~2034年CAR-T Cell Therapy Market Size, Share, Trends, Industry Analysis Report: By Indication, Target Antigen, and Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Market Forecast, 2025-2034 |
根據 Polaris Market Research 的最新研究,預計到 2034 年,全球 CAR-T 細胞治療市場規模將達到 1888.4 億美元。該報告提供了對當前市場動態的詳細洞察,並對未來市場成長進行了分析。
嵌合抗原受體 T 細胞 (CAR-T) 療法代表了癌症治療的進步,並徹底改變了免疫腫瘤學。這種治療是個人化的,透過改造患者的 T 細胞來表達針對特定癌症抗原的合成受體,對特定癌症(特別是血液系統惡性腫瘤)非常有效,從而提供了廣泛的治療選擇。在生物技術的快速進步、CAR-T療法批准率的提高以及對創新癌症治療的需求不斷增長的推動下,全球CAR-T細胞療法市場在過去十年中經歷了快速增長。
全球癌症發生率不斷上升,以及對精準醫療的日益青睞,推動了對 CAR-T 細胞療法等先進療法的需求。此外,支持性監管框架和加速審批途徑正在加速 CAR-T 療法的上市。政府和私人研究投資正在進一步推動CAR-T細胞治療市場的擴張。
下一代 CAR-T 療法(包括多標靶 CAR-T 細胞和裝甲 CAR-T 細胞)的發展正在推動 CAR-T 細胞療法市場的成長。多標靶 CAR-T 細胞旨在識別多種抗原,解決腫瘤異質性和抗原逃脫等限制傳統 CAR-T 治療有效性的問題。武裝CAR-T細胞旨在透過分泌細胞激素和其他分子來克服免疫抑制的腫瘤微環境,從而增強抗腫瘤活性。
CAR-T 療法的應用正在擴展到腫瘤學之外。研究人員正在探索其治療狼瘡和多發性硬化症等自體免疫疾病以及愛滋病毒等傳染病的潛力。這些新應用預計將顯著擴大市場範圍和影響力。
有跡象表明,濾泡性淋巴瘤 (FL) 領域預計將以最快的速度增長,在預測期內複合年增長率為 43.2%。
基於標靶抗原,CD19/CD22抗原片段在瀰漫性大B細胞淋巴瘤(DLBCL)和急性淋巴性白血病(ALL)等B細胞惡性腫瘤的治療中具有明確的作用並受到重視。達到62585億美元,佔最大市場佔有率。
在全球市場中,2024年北美CAR-T細胞治療市場佔47.16%的市佔率。這是由於先進的醫療基礎設施、高研發投資和血液惡性腫瘤的高盛行率。
由於復發性或難治性血癌盛行率上升以及人們越來越關注擴大先進治療的可及性,歐洲CAR-T 細胞治療市場將在預測期內增長,預計複合年增長率為33.2 %。
作為全球主要市場企業的一個例子,Bluebird Bio,Celgene Corporation,Gilead Sciences,Cellectis,Servier Laboratories,Pfizer Inc.,Merck,Amgen,Intellia Therapeutics,Novartis,Caribou Biosciences,Celyad,Bellicum Pharmaceuticals,Noile-Immune Biotech,南京市 Legend Biotechnology Co.等能舉出(舉行)。
The global CAR-T cell therapy market size is expected to reach USD 188.84 billion by 2034, according to a new study by Polaris Market Research. The report "CAR-T Cell Therapy Market Size, Share, Trends, Industry Analysis Report: By Indication, Target Antigen [CD19/CD22, BCMA (B-Cell Maturation Antigen), and Others], and Region (North America, Europe, Asia Pacific, Latin America, and Middle East & Africa) - Market Forecast, 2025-2034" gives a detailed insight into current market dynamics and provides analysis on future market growth.
Chimeric Antigen Receptor T-cell (CAR-T) therapy represents an advancement in cancer treatment, transforming immuno-oncology. The therapy offers personalized and highly effective treatment options for certain cancers, particularly hematological malignancies, by engineering a patient's T-cells to express synthetic receptors that target specific cancer antigens. The global CAR-T cell therapy market has witnessed exponential growth over the last decade, driven by rapid advancements in biotechnology, increasing approval rates of CAR-T therapies, and rising demand for innovative cancer treatments.
The increasing prevalence of cancer globally, coupled with a growing preference for precision medicine, has fueled demand for advanced treatment modalities such as CAR-T cell therapy. Moreover, supportive regulatory frameworks and rapid approval pathways have accelerated the availability of CAR-T therapies. Government and private investments in research further propel the CAR-T cell therapy market expansion.
The development of next-generation CAR-T therapies, including multi-target CAR-T cells and armored CAR-T cells, is driving the CAR-T cell therapy market growth. Multi-target CAR-T cells are engineered to recognize multiple antigens, addressing issues such as tumor heterogeneity and antigen escape, which limit the efficacy of traditional CAR-T treatments. Armored CAR-T cells are designed to overcome the immunosuppressive tumor microenvironment by secreting cytokines or other molecules to enhance anti-tumor activity.
The application of CAR-T therapy is expanding beyond oncology. Researchers are exploring its potential in treating autoimmune diseases such as lupus and multiple sclerosis and infectious diseases, including HIV. These novel applications are estimated to significantly broaden the market scope and impact.
In terms of indication, the follicular lymphoma (FL) segment is expected to grow at the fastest pace, with a CAGR of 43.2% during the forecast period due to the rising incidence of refractory and high-risk cancer cases.
Based on target antigen, the CD19/CD22 antigen segment, valued at USD 6,258.5 billion in 2024, held the largest market share owing to its established role in treating B-cell malignancies such as diffuse large B-cell lymphoma (DLBCL) and acute lymphoblastic leukemia (ALL).
In the global market, the North America CAR-T cell therapy market held a 47.16% market share in 2024 due to the presence of advanced healthcare infrastructure, significant research and development investments, and a high prevalence of hematologic malignancies.
The Europe CAR-T cell therapy market is expected to witness a CAGR of 33.2% during the forecast period due to increased focus on expanding access to advanced therapies, coupled with the rising prevalence of relapsed or refractory hematologic cancers.
A few of the global key market players are Bluebird Bio; Celgene Corporation; Gilead Sciences; Cellectis; Servier Laboratories; Pfizer Inc.; Merck; Amgen; Intellia Therapeutics; Novartis; Caribou Biosciences; Celyad; Bellicum Pharmaceuticals, Inc.; Noile-Immune Biotech; Nanjing Legend Biotechnology Co., Ltd.; Johnson & Johnson; and Sangamo Therapeutics, Inc.
Polaris Market Research has segmented the CAR-T cell therapy market report on the basis of indication, antigen, and region:
Chapter 1. Introduction
Chapter 2. Executive Summary
Chapter 3. Research Methodology
Chapter 4. CAR-T Cell Therapy Market Insights
Chapter 5. CAR-T Cell Therapy Market Assessment by Indication
Chapter 6. Global CAR-T Cell Therapy Market, by Target Antigen
Chapter 7. CAR-T Cell Therapy Market Assessment by Geography
Chapter 8. Competitive Landscape
Chapter 9. Company Profiles
Table 1 Selected significant catalysts in CAR-T
Table 2 Various antigen targets are investigated for solid tumors
Table 3 Top Developers in CAR T cell clinical trials (September 2019)
Table 4 Catalyst for Small Players
Table 5 Selected deals and partnerships
Table 6 Cost of production (Lentivirus), 2022, (USD Billion)
Table 7 Cost of production (Plasmid), 2022, (USD Billion)
Table 8 Reimbursement amounts for CAR-T therapies per region, 2022, (USD Billion)
Table 9 Global CAR-T Cell Therapy Market, by Indication, 2020-2034, (USD Billion)
Table 10 Global CAR-T Cell Therapy Market, by DLBCL, 2020-2034, (USD Billion)
Table 11 Global CAR-T Cell Therapy Market, by ALL, 2020-2034, (USD Billion)
Table 12 Global CAR-T Cell Therapy Market, by CLL, 2020-2034, (USD Billion)
Table 13 Global CAR-T Cell Therapy Market, by MM, 2020-2034, (USD Billion)
Table 14 Global CAR-T Cell Therapy Market, by FL, 2020-2034, (USD Billion)
Table 15 Global CAR-T Cell Therapy Market, by Mastozytosis, 2020-2034, (USD Billion)
Table 16 Global CAR-T Cell Therapy Market, by Myeloid Fibrosis, 2020-2034, (USD Billion)
Table 17 Global CAR-T Cell Therapy Market, by MLL, 2020-2034, (USD Billion)
Table 18 Global CAR-T Cell Therapy Market, by Thymic Cancer, 2020-2034, (USD Billion)
Table 19 Global CAR-T Cell Therapy Market, by Glioblastoma, 2020-2034, (USD Billion)
Table 20 Global CAR-T Cell Therapy Market, by AML, 2020-2034, (USD Billion)
Table 21 Global CAR-T Cell Therapy Market, by Other Indications, 2020-2034, (USD Billion)