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mRNA 合成與製造市場：產業趨勢與 2035 年全球預測 - 依產品類型、應用領域、治療領域和關鍵區域
市場調查報告書
商品編碼
1479826

mRNA 合成與製造市場：產業趨勢與 2035 年全球預測 - 依產品類型、應用領域、治療領域和關鍵區域

mRNA Synthesis and Manufacturing Market : Industry Trends and Global Forecasts, till 2035 - Distribution by Type of Product (Drug Substances and Drug Products ), Application Area, Therapeutic Area and Key Geographical Regions
出版日期: | 出版商: Roots Analysis | 英文 170 Pages | 商品交期: 最快1-2個工作天內

價格

核糖核酸 (RNA) 是一種普遍存在於所有活細胞中的分子，負責將遺傳訊息轉化為蛋白質，對多種細胞過程非常重要。RNA 有多種形式，包括信使 RNA (mRNA)、轉移 RNA (tRNA) 和核醣體 RNA (rRNA)，而 mRNA 正在成為現代醫療保健中的重要治療工具。mRNA 上的遺傳密碼被翻譯成胺基酸並加工成功能性蛋白質。自COVID-19大流行以來，mRNA疫苗和治療藥物的生產引起了極大關注，並正在成為不僅針對COVID-19而且針對腫瘤疾病、傳染病和遺傳疾病等多種疾病的下一代藥物類別。是。

然而，製造 mRNA 療法和疫苗是一個複雜且昂貴的過程，需要專門的知識和能力。因此，mRNA 療法和疫苗的開發者正在積極尋求解決方案來克服這些課題。外包已成為 mRNA 開發商的一個有吸引力的選擇，為這些障礙提供了潛在的解決方案。未來，由於慢性疾病的增加、基因治療需求的增加、基於RNA的療法在臨床和商業階段的成熟以及技術的進步，預計mRNA合成和製造市場將穩定成長。

該報告考察了全球 mRNA 合成和製造市場，並依產品類型、應用領域、治療領域、地區以及參與市場的公司概況提供了市場概況、趨勢。

目錄

第一章 前言

第二章 研究方法

第 3 章. 經濟和其他專案特定考慮因素

第 4 章執行摘要

第 5 章 簡介

第六章 mRNA客製化合成服務商：市場狀況

第七章 mRNA客製化合成服務商：企業競爭力分析

第八章 公司簡介：mRNA客製合成服務商

第九章 mRNA合約製造服務提供者：市場狀況

第十章 mRNA代工服務商：企業競爭力分析

第十一章 公司簡介：mRNA合約製造服務供應商

第十二章 mRNA合成試劑盒供應商：市場狀況

第十三章 mRNA合成試劑盒：產品競爭力分析

第十四章 公司簡介：mRNA合成試劑盒提供商

第 15 章 夥伴關係與合作

第十六章 潛力夥伴分析

第十七章 各大藥企的舉措

第十八章市場影響分析：驅動因素、限制因素、機會、課題

  • 章節概述
  • 市場驅動力
  • 市場限制
  • 市場機會
  • 市場課題

第十九章 全球mRNA合成及製造市場

  • 章節概述
  • 主要假設和預測研究方法
  • 全球mRNA合成和製造市場、歷史趨勢（2021-2023）和預測（2024-2035）（十億美元）
  • 主要市場區隔

第 20 章 mRNA 合成與製造市場（依產品類型）

第21章 mRNA合成與製造市場，依應用領域

第22章 mRNA合成與製造市場，依治療領域

第23章 mRNA合成與製造市場，依主要地區

第24章高階主管見解

第25章附錄1：表格數據

第二十六章 附錄2：公司與組織名單

Product Code: RA100401

mRNA Synthesis and Manufacturing Market (3rd Edition): Industry Trends and Global Forecasts, till 2035 - Distribution by Type of Product (Drug Substances (APIs) and Drug Products (FDFs)), Application Area (mRNA-based Vaccines and mRNA-based Therapeutics), Therapeutic Area (Infectious Diseases, Oncological Disorders and Other Disorders) and Key Geographical Regions (North America, Europe, Asia-Pacific and Rest of the World)

The mRNA Synthesis and Manufacturing Market is valued at USD 1.06 billion in 2024.

Ribonucleic acid (RNA) is a ubiquitous molecule found in all the living cells, which is responsible for translating genetic information into proteins which is important for various cellular processes. RNA comes in different forms, including messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA), with mRNA emerging as a prominent therapeutic modality in modern healthcare. mRNA is a single-stranded molecule that carries genetic information from DNA to produce proteins. This genetic code on mRNA is translated into amino acids, which are then processed into functional proteins. Since the onset of the COVID-19 pandemic, mRNA vaccine and therapeutic manufacturing have garnered considerable attention, emerging as a next-generation drug class not only for COVID-19 but also for various other conditions like oncological disorders, infectious diseases, and genetic disorders.

However, producing mRNA therapeutics and vaccines is a complex and expensive process which demands specialized expertise and capabilities. Consequently, developers of mRNA therapeutics and vaccines are actively exploring solutions to overcome these challenges. Outsourcing has emerged as an attractive option for mRNA developers, offering potential solutions to these hurdles. Looking ahead, with the increasing prevalence of chronic diseases, growing demand for gene therapy, maturation of RNA-based therapies in clinical and commercial stages, and advancements in technology, we anticipate robust growth in the mRNA synthesis and manufacturing market.

Key Market Segments

Type of Product

Drug Substance (APIs)

Drug Product (FDFs)

Application Area

mRNA-based Vaccines

mRNA-based Therapeutics

Therapeutic Area

Infectious Diseases

Oncological Disorders

Other Diseases

Key Geographical Regions

North America

Europe

Asia-Pacific

Rest of the World

Research Coverage:

An overview of structure and the historical evolution of mRNA vaccines. A comprehensive discussion pertaining the information on the synthetic mRNA production, both chemically and in vitro, and its applications across various therapeutic area. Further, it features the challenges associated with the synthesis and manufacturing processes of mRNA are outlined as well. Further, the module delves into the commonly outsourced manufacturing operations and their advantages.

A comprehensive evaluation of mRNA custom synthesis service providers, considering several relevant parameters, such as year of establishment, company size (measured by the number of employees), headquarters location (North America, Europe, and Asia Pacific), types of services offered (such as mRNA modification, purification, scale-up, process development, and fill/finish), starting material (plasmid DNA, mRNA sequence, PCR fragments), structural modification (5' modification, 3' modification, ribonucleotide base modification, and others), purification methods (chromatography, electrophoresis, desalting/precipitation, and others), application areas (vaccine production, therapeutic production, and others), and scale of operation (preclinical/research, clinical, and commercial). Additionally, the chapter includes information on the length of the mRNA manufactured and the production capacity of the stakeholders.

An in-depth competitiveness analysis of mRNA custom synthesis service providers across key geographical regions. This analysis takes into account the supplier strength, including years of experience and company size, as well as service strength, which encompasses the number and types of services offered, modifications, scale of operation, compliance with Good Manufacturing Practices (GMP), and application areas.

A thorough assessment of mRNA contract manufacturing service providers, considering various pertinent parameters. These parameters include the year of establishment, company size (measured by the number of employees), headquarters location (North America, Europe, and Asia Pacific), location of manufacturing facilities, types of additional services offered (such as formulation development, analytical testing, process development, mRNA purification, fill / finish, scale-up, regulatory support, and others), type of product manufactured (drug substances (APIs) and drug products (FDFs)), and scale of operation (preclinical/research, clinical, and commercial).

A thorough company competitiveness analysis of mRNA contract manufacturing service providers across key geographical regions, focusing on the supplier strength and service portfolio strength. Supplier strength is assessed based on years of experience and company size, while service portfolio strength considers factors such as the number of facilities, type of products manufactured, variety of services offered, and scale of operation.

A comprehensive evaluation of the current market landscape of mRNA synthesis kits, considering various pertinent parameters. These parameters include kit components (such as enzyme mix, reagents, buffer, etc.), types of enzymes utilized (including capping enzyme and tailing enzyme), enzyme mix variants (such as T7 polymerase, SP6 polymerase, and T3 polymerase), mRNA components modified (cap, base, and tail), number of reactions per kit (ranging from 5 to 50 reactions), yield per reaction (categorized by microgram ranges), reaction run time (classified by duration), and kit price (grouped into price ranges). Furthermore, the chapter provides an extensive analysis of mRNA synthesis kit providers, offering insights into their year of establishment, company size (measured by employee count), headquarters location, and the most active players in terms of the number of mRNA synthesis kits offered.

A detailed analysis of mRNA synthesis kits, focusing on the supplier strength and product attributes. Supplier strength is evaluated based on years of experience and company size, while product strength is assessed based on the number of kit components, types of enzymes included, types of mRNA components modified, yield per reaction, number of reactions per kit, reaction run time, and kit price.

Detailed company profiles of the top mRNA manufacturing companies based on their robust service offerings. Each profile includes a concise company overview, encompassing establishment year, headquarters location, employee count, and notable executives. Additionally, it delves into their mRNA synthesis and manufacturing services, recent advancements, and well-informed future perspectives. Further, the leading service providers in mRNA synthesis and manufacturing, profiles of other noteworthy players have been included, featuring company background and mRNA synthesis and manufacturing service details.

Comprehensive profiles of leading mRNA synthesis kit providers have been curated, selected for their robust product portfolios. Each profile provides a succinct company overview, coupled with details on their mRNA synthesis kits portfolio.

An exhaustive examination of partnerships formed among stakeholders within this industry between 2019 and 2023, taking into account various parameters. These parameters include the year of partnership, nature of partnership, product type, partner type, and identification of the most prolific players based on the quantity of partnerships forged. Furthermore, the analysis offers insights into the regional distribution of the companies engaged in these collaborations.

A comprehensive analysis of over 35 developers of mRNA-based therapeutics and vaccines, identified for potential partnerships with mRNA contract manufacturing service providers. These developers have been carefully shortlisted based on various parameters including the strength of the developer (evaluated through company experience), company size (measured by the number of employees), pipeline robustness (assessed by the quantity of mRNA-based drugs in the pipeline), highest development phase attained, therapeutic focus, route of administration, and the type of candidates under development.

An comprehensive examination of the diverse mRNA-focused initiatives undertaken by major pharmaceutical companies, selected based on their 2023 revenues. This review highlights trends across multiple parameters, including the quantity of initiatives, initiation year, purpose, type, and therapeutic focus of each initiative.

A detailed analysis on the factors influencing the growth of the mRNA synthesis and manufacturing market. This study includes the identification and examination of key drivers propelling market expansion, potential restraints hindering growth, emerging opportunities for market advancement, and existing challenges that may impede progress.

In-depth forecast analysis of the mRNA synthesis and manufacturing market to estimate both the current market size and the future opportunities up to the year 2035. Utilizing multiple parameters such as anticipated adoption trends and rigorous primary validations, we have derived an informed estimate of the market evolution during the forecast period from 2024 to 2035. Furthermore, this module outlines the likely distribution of the current and forecasted opportunities within the mRNA synthesis and manufacturing market. To enhance the robustness of our model and to accommodate future uncertainties, we have developed three forecast scenarios: conservative, base, and optimistic. These scenarios represent different trajectories of industry growth, providing a comprehensive perspective on potential market developments.

Detailed projections have been formulated for the current and future mRNA synthesis and manufacturing market, categorized by type of product, encompassing both drug substances and drug products. These projections offer comprehensive insights into the anticipated growth trajectories, market sizes, and emerging trends for each product type within the mRNA synthesis and manufacturing landscape.

Detailed projections of the current and future mRNA synthesis and manufacturing market across application area, such as mRNA-based vaccines and mRNA-based therapeutics.

Detailed projections of the current and future mRNA synthesis and mRNA manufacturing market across therapeutic area, such as infectious diseases, oncological disorders and other disorders.

Detailed projections of the current and future mRNA synthesis and manufacturing market across key geographies, such as North America, Europe, Asia-Pacific, and Rest of the World.

Key Benefits of Buying this Report

The report offers market leaders and newcomers valuable insights into revenue estimations for both the overall market and its sub-segments.

Stakeholders can utilize the report to enhance their understanding of the competitive landscape, allowing for improved business positioning and more effective go-to-market strategies.

The report provides stakeholders with a pulse on the mRNA Synthesis and Manufacturing Market, furnishing them with essential information on significant market drivers, barriers, opportunities, and challenges.

Leading Market Companies

Aldevron

APExBIO

Aurigene Pharmaceutical Services

Biomay

CELLSCRIPT

Curia

eTheRNA

Enzynomics

Eurogentec

Genscript

Jena Bioscience

Merck KGaA

New England Biolabs

Vernal Biosciences

ST Pharm

Thermo Fisher Scientific

TriLink BioTechnologies

WuXi Biologics

TABLE OF CONTENTS

1. PREFACE

  • 1.1. mRNA Synthesis and mRNA Manufacturing Market
  • 1.2. Market Share Insights
    • 1.2.1. Market Segmentation Overview
  • 1.3. Key Market Insights
  • 1.4. Report Coverage
  • 1.5. Key Questions Answered
  • 1.6. Chapter Outlines

2. RESEARCH METHODOLOGY

  • 2.1. Chapter Overview
  • 2.2. Research Assumptions
  • 2.3. Project Methodology
  • 2.4. Forecast Methodology
  • 2.5. Robust Quality Control
  • 2.6. Key Market Segmentations
  • 2.7. Key Considerations
    • 2.7.1. Demographics
    • 2.7.2. Economic Factors
    • 2.7.3. Government Regulations
    • 2.7.4. Supply Chain
    • 2.7.5. COVID Impact / Related Factors
    • 2.7.6. Market Access
    • 2.7.7. Healthcare Policies
    • 2.7.8. Industry Consolidation

3. ECONOMIC AND OTHER PROJECT SPECIFIC CONSIDERATIONS

  • 3.1. Chapter Overview
  • 3.2. Market Dynamics
    • 3.2.1. Time Period
      • 3.2.1.1. Historical Trends
      • 3.2.1.2. Current and Forecasted Estimates
    • 3.2.2. Currency Coverage
      • 3.2.2.1. Overview of Major Currencies Affecting the Market
      • 3.2.2.2. Impact of Currency Fluctuations on the Industry
    • 3.2.3. Foreign Exchange Impact
      • 3.2.3.1. Evaluation of Foreign Exchange Rates and Their Impact on Market
      • 3.2.3.2. Strategies for Mitigating Foreign Exchange Risk
    • 3.2.4. Recession
      • 3.2.4.1. Historical Analysis of Past Recessions and Lessons Learnt
      • 3.2.4.2. Assessment of Current Economic Conditions and Potential Impact on the Market
    • 3.2.5. Inflation
      • 3.2.5.1. Measurement and Analysis of Inflationary Pressures in the Economy
      • 3.2.5.2. Potential Impact of Inflation on the Market Evolution

4. EXECUTIVE SUMMARY

5. INTRODUCTION

  • 5.1. Overview of mRNA
  • 5.2. Structure of mRNA
  • 5.3. Evolution of mRNA Vaccines
  • 5.4. Steps involved in mRNA Synthesis
    • 5.4.1. Chemical Synthesis of mRNA
    • 5.4.2. In vitro Synthesis of mRNA
  • 5.5. Applications of Chemical/ in vitro Synthesized mRNA
  • 5.6. Challenges Associated with mRNA Synthesis
  • 5.7. mRNA Contract Manufacturing
    • 5.7.1. Commonly Outsourced mRNA Manufacturing Operations
    • 5.7.2. Advantages of Outsourcing Manufacturing Operations

6. mRNA CUSTOM SYNTHESIS SERVICE PROVIDERS: MARKET LANDSCAPE

  • 6.1. mRNA Custom Synthesis Service Providers: Market Landscape
    • 6.1.1. Analysis by Year of Establishment
    • 6.1.2. Analysis by Company Size
    • 6.1.3. Analysis by Location of Headquarters
    • 6.1.4. Analysis by Type of Service Offered
    • 6.1.5. Analysis by Starting Material
    • 6.1.6. Analysis by Structural Modification
    • 6.1.7. Analysis by Type of Purification Method
    • 6.1.8. Analysis by Application Area
    • 6.1.9. Analysis by Scale of Operation
    • 6.1.10. mRNA Custom Synthesis Service Providers: Information on Length (Base Pair) of mRNA Synthesized
    • 6.1.11. mRNA Custom Synthesis Service Providers: Information on mRNA Production Capacity

7. mRNA CUSTOM SYNTHESIS SERVICE PROVIDERS: COMPANY COMPETITIVENESS ANALYSIS

  • 7.1. Chapter Overview
  • 7.2. Assumptions and Methodology
  • 7.3. Scoring Criteria
  • 7.4. mRNA Custom Synthesis Service Providers: Company Competitiveness Analysis
    • 7.4.1. mRNA Custom Synthesis Service Providers based in North America
    • 7.4.2. mRNA Custom Synthesis Service Providers based in Europe
    • 7.4.3. mRNA Custom Synthesis Service Providers based in Asia-Pacific

8. COMPANY PROFILES: mRNA CUSTOM SYNTHESIS SERVICE PROVIDERS

  • 8.1. Chapter Overview
  • 8.2. Detailed Company Profiles of Leading Service Providers
    • 8.2.1. Aldevron
      • 8.2.1.1. Company Overview
      • 8.2.1.2. mRNA Custom Synthesis Service Portfolio
      • 8.2.1.3. Recent Developments and Future Outlook
    • 8.2.2. TriLink BioTechnologies
      • 8.2.2.1. Company Overview
      • 8.2.2.2. mRNA Custom Synthesis Service Portfolio
      • 8.2.2.3. Recent Developments and Future Outlook
    • 8.2.3. eTheRNA
      • 8.2.3.1. Company Overview
      • 8.2.3.2. mRNA Custom Synthesis Service Portfolio
      • 8.2.3.3. Recent Developments and Future Outlook
  • 8.3. Short Profiles of Other Prominent Custom Service Providers
    • 8.3.1. Biomay
      • 8.3.1.1. Company Overview
      • 8.3.1.2. mRNA Custom Synthesis Service Portfolio
    • 8.3.2. Genscript
      • 8.3.2.1. Company Overview
      • 8.3.2.2. mRNA Custom Synthesis Service Portfolio
    • 8.3.3. Aurigene Pharmaceutical Services
      • 8.3.3.1. Company Overview
      • 8.3.3.2. mRNA Custom Synthesis Service Portfolio

9. mRNA CONTRACT MANUFACTURING SERVICE PROVIDERS: MARKET LANDSCAPE

  • 9.1. mRNA Contract Manufacturing Service Providers: Market Landscape
    • 9.1.1. Analysis by Year of Establishment
    • 9.1.2. Analysis by Company Size
    • 9.1.3. Analysis by Location of Headquarters (Region)
    • 9.1.4. Analysis by Location of Headquarters (Country)
    • 9.1.5. Analysis by Location of Manufacturing Facility
    • 9.1.6. Analysis by Type of Additional Services
    • 9.1.7. Analysis by Type of Product Manufactured
    • 9.1.8. Analysis by Scale of Operation

10. mRNA CONTRACT MANUFACTURING SERVICE PROVIDERS: COMPANY COMPETITIVENESS ANALYSIS

  • 10.1. Chapter Overview
  • 10.2. Assumptions and Methodology
  • 10.3. Scoring Criteria
  • 10.4. mRNA Contract Manufacturing Service Providers: Company Competitiveness Analysis
    • 10.4.1. mRNA Contract Manufacturing Service Providers based in North America
    • 10.4.2. mRNA Contract Manufacturing Service Providers based in Europe
    • 10.4.3. mRNA Contract Manufacturing Service Providers based in Asia-Pacific

11. COMPANY PROFILES: mRNA CONTRACT MANUFACTURING SERVICE PROVIDERS

  • 11.1. Chapter Overview
  • 11.2. Detailed Company Profiles of Leading Service Providers
    • 11.2.1. Eurogentac
      • 11.2.1.1. Company Overview
      • 11.2.1.2. mRNA Contract Manufacturing Services Portfolio
      • 11.2.1.3. Recent Developments and Future Outlook
    • 11.2.2. WuXi Biologics
      • 11.2.2.1. Company Overview
      • 11.2.2.2. mRNA Contract Manufacturing Services Portfolio
      • 11.2.2.3. Recent Developments and Future Outlook
    • 11.2.3. Merck
      • 11.2.3.1. Company Overview
      • 11.2.3.2. mRNA Contract Manufacturing Services Portfolio
      • 11.2.3.3. Recent Developments and Future Outlook
  • 11.3. Short Profiles of Other Prominent Service Providers
    • 11.3.1. ST Pharm
      • 11.3.1.1. Company Overview
      • 11.3.1.2. mRNA Contract Manufacturing Services Portfolio
    • 11.3.2. Vernal Biosciences
      • 11.3.2.1. Company Overview
      • 11.3.2.2. mRNA Contract Manufacturing Services Portfolio
    • 11.3.3. Curia
      • 11.3.3.1. Company Overview
      • 11.3.3.2. mRNA Contract Manufacturing Services Portfolio

12. mRNA SYNTHESIS KIT PROVIDERS: MARKET LANDSCAPE

  • 12.1. mRNA Synthesis Kits: Market Landscape
    • 12.1.1. Analysis by Kit Components
    • 12.1.2. Analysis by Type of Enzyme
    • 12.1.3. Analysis by Type of Enzyme Mix Used
    • 12.1.4. Analysis by mRNA Component Modified
    • 12.1.5. Analysis by Number of Reaction
    • 12.1.6. Analysis by Yield per Reaction
    • 12.1.7. Analysis by Reaction Run-time
    • 12.1.8. Analysis by Kit Price
    • 12.1.9. Most Active Players: Analysis by Number of Kits Offered
  • 12.2. mRNA Synthesis Kits: Providers Landscape
    • 12.2.1. Analysis by Year of Establishment
    • 12.2.2. Analysis by Company Size
    • 12.2.3. Analysis by Location of Headquarters

13. mRNA SYNTHESIS KITS: PRODUCT COMPETITIVENESS ANALYSIS

  • 13.1. Chapter Overview
  • 13.2. Assumptions and Methodology
  • 13.3. Scoring Criteria
  • 13.4. mRNA Synthesis Kits: Product Competitiveness Analysis

14. COMPANY PROFILES: mRNA SYNTHESIS KIT PROVIDERS

  • 14.1. Chapter Overview
  • 14.2. Jena Biosciences
    • 14.2.1. Company Overview
    • 14.2.2. mRNA Synthesis Kits Portfolio
  • 14.3. APExBIO
    • 14.3.1. Company Overview
    • 14.3.2. mRNA Synthesis Kits Portfolio
  • 14.4. Thermo Fisher Scientific
    • 14.4.1. Company Overview
    • 14.4.2. mRNA Synthesis Kits Portfolio
  • 14.5. CELLSCRIPT
    • 14.5.1. Company Overview
    • 14.5.2. mRNA Synthesis Kits Portfolio
  • 14.6. New England Biolabs
    • 14.6.1. Company Overview
    • 14.6.2. mRNA Synthesis Kits Portfolio
  • 14.7. Enzynomics
    • 14.7.1. Company Overview
    • 14.7.2. mRNA Synthesis Kits Portfolio

15. PARTNERSHIPS AND COLLABORATIONS

  • 15.1. Partnership Models
  • 15.2. mRNA Synthesis and Manufacturing: Partnerships and Collaborations
    • 15.1.1. Analysis by Year of Partnership
    • 15.1.2. Analysis by Type of Partnership
    • 15.1.3. Analysis by Year and Type of Partnership
    • 15.1.4. Analysis by Type of Product
    • 15.1.5. Analysis by Type of Partner
    • 15.1.6. Most Active Players: Analysis by Number of Partnerships
    • 15.1.7. Analysis by Geography
      • 15.1.7.1. Intracontinental and Intercontinental Deals
      • 15.1.7.2. Local and International Deals

16. LIKELY PARTNER ANALYSIS

  • 16.1. Methodology and Key Parameters
  • 16.2. Scoring Criteria
  • 16.3. mRNA Drug Developers: Likely Partners based in North America
    • 16.3.1. mRNA Drug Developers: Most Likely Partners based in North America
  • 16.4. mRNA Drug Developers: Likely Partners based in Europe
    • 16.4.1. mRNA Drug Developers: Most Likely Partners based in Europe
  • 16.5. mRNA Drug Developers: Likely Partners based in Asia-Pacific and Rest of the World
    • 16.5.1. mRNA Drug Developers: Most Likely Partners based in Asia-Pacific and Rest of the World

17. BIG PHARMA INITIATIVES

  • 17.1. Analysis Methodology
  • 17.2. Scoring Criteria
  • 17.3. Big Pharma Players: mRNA- focused Initiatives
  • 17.4. Competitive Benchmarking of Big Pharma Players

18. MARKET IMPACT ANALYSIS: DRIVERS, RESTRAINTS, OPPORTUNITIES AND CHALLENGES

  • 18.1. Chapter Overview
  • 18.2. Market Drivers
  • 18.3. Market Restraints
  • 18.4. Market Opportunities
  • 18.5. Market Challenges

19. GLOBAL mRNA SYNTHESIS AND MANUFACTURING MARKET

  • 19.1. Chapter Overview
  • 19.2. Key Assumptions and Forecast Methodology
  • 19.3. Global mRNA Synthesis and Manufacturing Market, Historical Trends (2021-2023) and Forecasted Estimates (2024-2035) (USD Billion)
    • 19.3.1. Scenario Analysis
  • 19.4. Key Market Segmentations

20. mRNA SYNTHESIS AND MANUFACTURING MARKET, BY TYPE OF PRODUCT

  • 20.1. Chapter Overview
  • 20.2. Key Assumptions and Forecast Methodology
  • 20.3. mRNA Synthesis and Manufacturing Market: Distribution by Type of Product, 2021, 2024 and 2035
    • 20.3.1. mRNA Synthesis and Manufacturing: Market for Drug Substances (APIs), till 2035 (USD Billion)
    • 20.3.2. mRNA Synthesis and Manufacturing Market for Drug Products (FDFs), till 2035 (USD Billion)

21. mRNA SYNTHESIS AND MANUFACTURING MARKET, BY APPLICATION AREA

  • 21.1. Chapter Overview
  • 21.2. Key Assumptions and Forecast Methodology
  • 21.3. mRNA Synthesis and Manufacturing Market: Distribution by Application Area, 2021, 2024 and 2035
    • 21.3.1. mRNA Synthesis and Manufacturing Market for mRNA-based Vaccines, till 2035 (USD Billion)
    • 21.3.2. mRNA Synthesis and Manufacturing Market for mRNA-based Therapeutics, till 2035 (USD Billion)

22. mRNA SYNTHESIS AND MANUFACTURING MARKET, BY THERAPEUTIC AREA

  • 22.1. Chapter Overview
  • 22.2. Key Assumptions and Forecast Methodology
  • 22.3. mRNA Synthesis and Manufacturing Market: Distribution by Therapeutic Area, 2021, 2023 and 2035
    • 22.3.1. mRNA Synthesis and Manufacturing Market for Infectious Diseases, till 2035 (USD Billion)
    • 22.3.2. mRNA Synthesis and Manufacturing Market for Oncological Disorders, till 2035 (USD Billion)
    • 22.3.3 mRNA Synthesis and Manufacturing Market for Other Disorders, till 2035 (USD Billion)

23. mRNA SYNTHESIS AND MANUFACTURING MARKET, BY KEY GEOGRAPHICAL REGIONS

  • 23.1. Chapter Overview
  • 23.2. Key Assumptions and Forecast Methodology
  • 23.3. mRNA Synthesis and Manufacturing Market: Distribution by Key Geographical Regions, 2021, 2024 and 2035
    • 23.3.1 mRNA Synthesis and Manufacturing Market in North America, till 2035 (USD Billion)
    • 23.3.2. mRNA Synthesis and Manufacturing Market in Europe, till 2035 (USD Billion)
    • 23.3.3. mRNA Synthesis and Manufacturing Market in Asia-Pacific, till 2035 (USD Billion)
    • 23.3.4. mRNA Synthesis and Manufacturing Market in Latin America, till 2035 (USD Billion)
    • 23.3.5. mRNA Synthesis and Manufacturing Market in Middle East and North Africa, till 2035 (USD Billion)
    • 23.3.6. mRNA Synthesis and Manufacturing Market in Rest of the World, till 2035, USD Billion

24. EXECUTIVE INSIGHTS

  • 24.1. Chapter Overview
  • 24.2. Canvax
    • 24.2.1. Company Snapshot
    • 24.2.2. Interview Transcript: Bernardo Jose Gomez Fernandez, Business Development Manager
  • 24.3. GC Pharma
    • 24.3.1. Company Snapshot
    • 24.3.2. Interview Transcript: Jaehoon Moon, Team Leader
  • 24.4 Tebubio
    • 24.4.1. Company Snapshot
    • 24.4.2. Interview Transcript: Jean-Francois, Chief Commercial Officer

25. APPENDIX 1: TABULATED DATA

26. APPENDIX 2: LIST OF COMPANIES AND ORGANIZATIONS

List of Tables

  • Table 6.1 List of mRNA Custom Synthesis Service Providers
  • Table 6.2 mRNA Custom Synthesis Service Providers: Information on Length (Base Pair) of mRNA Synthesized
  • Table 6.3 mRNA Custom Synthesis Service Providers: Information on mRNA Production Capacity
  • Table 8.1 Aldevron: mRNA Custom Synthesis Service Portfolio
  • Table 8.2 TriLink Biotechnologies: mRNA Custom Synthesis Service Portfolio
  • Table 8.3 etheRNA: mRNA Custom Synthesis Service Portfolio
  • Table 8.4 Biomay: mRNA Custom Synthesis Service Portfolio
  • Table 8.5 GenScript: mRNA Custom Synthesis Service Portfolio
  • Table 8.6 Aurigene Pharmaceutical Services: mRNA Custom Synthesis Service Portfolio
  • Table 9.1 List of mRNA Contract Manufacturing Service Providers
  • Table 11.1 Eurogentec: mRNA Contract Manufacturing Service Portfolio
  • Table 11.2 Wuxi Biologics: mRNA Contract Manufacturing Service Portfolio
  • Table 11.3 Merck: mRNA Contract Manufacturing Service Portfolio
  • Table 11.4 ST Pharm: mRNA Contract Manufacturing Service Portfolio
  • Table 11.5 Vernal Biosciences: mRNA Contract Manufacturing Service Portfolio
  • Table 11.6 Curia: mRNA Contract Manufacturing Service Portfolio
  • Table 12.1 List of mRNA Synthesis Kits
  • Table 12.2 List of mRNA Synthesis Kit Providers
  • Table 14.1 Jena Biosciences: mRNA Synthesis Kits Portfolio
  • Table 14.2 APExBIO: mRNA Synthesis Kits Portfolio
  • Table 14.3 ThermoFisher Scientific: mRNA Synthesis Kits Portfolio
  • Table 14.4 CELLSCRIPT: mRNA Synthesis Kits Portfolio
  • Table 14.5 New England Biolabs: mRNA Synthesis Kits Portfolio
  • Table 14.6 Enzynomics: mRNA Synthesis Kits Portfolio
  • Table 15.1 mRNA Synthesis and Manufacturing Services: List of Partnerships and Collaborations, 2019-2023
  • Table 17.1 Big Pharma Players: List of mRNA Focused Initiatives, 2019-2023
  • Table 25.1 mRNA Custom Synthesis Service Providers: Distribution by Year of Establishment
  • Table 25.2 mRNA Custom Synthesis Service Providers: Distribution by Company Size
  • Table 25.3 mRNA Custom Synthesis Service Providers: Distribution by Location of Headquarters
  • Table 25.4 mRNA Custom Synthesis Service Providers: Distribution by Type of Service Offered
  • Table 25.5 mRNA Custom Synthesis Service Providers: Distribution by Starting Material
  • Table 25.6 mRNA Custom Synthesis Service Providers: Distribution by Structural Modification
  • Table 25.7 mRNA Custom Synthesis Service Providers: Distribution by Type of Purification Method
  • Table 25.8 mRNA Custom Synthesis Service Providers: Distribution by Application Area
  • Table 25.9 mRNA Custom Synthesis Service Providers: Distribution by Scale of Operation
  • Table 25.10 mRNA Contract Manufacturing Service Providers: Distribution by Year of Establishment
  • Table 25.11 mRNA Contract Manufacturing Service Providers: Distribution by Company Size
  • Table 25.12 mRNA Contract Manufacturing Service Providers: Distribution by Location of Headquarters
  • Table 25.13 mRNA Contract Manufacturing Service Providers: Distribution by Location of Manufacturing Facilities
  • Table 25.14 mRNA Contract Manufacturing Service Providers: Distribution by Type of Additional Services
  • Table 25.15 mRNA Contract Manufacturing Service Providers: Distribution by Type of Product Manufactured
  • Table 25.16 mRNA Contract Manufacturing Service Providers: Distribution by Scale of Operation
  • Table 25.17 mRNA Synthesis Kits: Distribution by Kit Components
  • Table 25.18 mRNA Synthesis Kits: Distribution by Type of Enzymes
  • Table 25.19 mRNA Synthesis Kits: Distribution by Type of Enzyme Mix Used
  • Table 25.20 mRNA Synthesis Kits: Distribution by mRNA Component Modified
  • Table 25.21 mRNA Synthesis Kits: Distribution by Number of Reactions
  • Table 25.22 mRNA Synthesis Kits: Distribution by Yield per Reaction
  • Table 25.23 mRNA Synthesis Kits: Distribution by Reaction Run-time
  • Table 25.24 mRNA Synthesis Kits: Distribution by Price of Kits
  • Table 25.25 Most Active Players: Distribution by Number of Kits Offered
  • Table 25.26 mRNA Synthesis Kit Providers: Distribution by Year of Establishment
  • Table 25.27 mRNA Synthesis Kit Providers: Distribution by Company Size
  • Table 25.28 mRNA Synthesis Kit Providers: Distribution by Location of Headquarters
  • Table 25.29 Partnerships and Collaborations: Distribution by Year of Partnership
  • Table 25.30 Partnerships and Collaborations: Distribution by Type of Partnership
  • Table 25.31 Partnerships and Collaborations: Distribution by Year and Type of Partnership
  • Table 25.32 Partnerships and Collaborations: Distribution by Type of Product (Broad)
  • Table 25.33 Partnerships and Collaborations: Distribution by Type of Product (Specific)
  • Table 25.34 Partnerships and Collaborations: Distribution by Type of Partner
  • Table 25.35 Most Active Players: Distribution by Number of Partnerships
  • Table 25.36 Partnerships and Collaborations: Intercontinental and Intracontinental Deals
  • Table 25.37 Partnerships and Collaborations: Local and International Deals
  • Table 25.38 Global mRNA Synthesis and Manufacturing Market, Historical Trends (2021-2023) and Forecasted Estimates (2024-2032) (USD Billion)
  • Table 25.39 Global mRNA Synthesis and Manufacturing Market, Forecasted Estimates (2024-2032) (Conservative Scenario) (USD Billion)
  • Table 25.40 Global mRNA Synthesis and Manufacturing Market, Forecasted Estimates (2024-2032) (Optimistic Scenario) (USD Billion)
  • Table 25.41 mRNA Synthesis and Manufacturing Market: Distribution by Type of Product, 2021, 2024, and 2035
  • Table 25.42 mRNA Synthesis and Manufacturing Market for Drug Substances (APIs), till 2035 (USD Billion)
  • Table 25.43 mRNA Synthesis and Manufacturing Market for Drug Products (FDFs) till 2035 (USD Billion)
  • Table 25.44 mRNA Synthesis and Manufacturing Market: Distribution by Application Area, 2021, 2024, and 2035
  • Table 25.45 mRNA Synthesis and Manufacturing Market for mRNA-based Vaccines, till 2035 (USD Billion)
  • Table 25.46 mRNA Synthesis and Manufacturing Market for mRNA-based Therapeutics, till 2035 (USD Billion)
  • Table 25.47 mRNA Synthesis and Manufacturing Market: Distribution by Therapeutic Area, 2021, 2024 and 2035
  • Table 25.48 mRNA Synthesis and Manufacturing Market for Infectious Diseases, till 2035 (USD Billion)
  • Table 25.49 mRNA Synthesis and Manufacturing Market for Oncological Disorders, till 2035 (USD Billion)
  • Table 25.50 mRNA Synthesis and Manufacturing Market for Other Disorders, till 2035 (USD Billion)
  • Table 25.51 mRNA Synthesis and Manufacturing Market: Distribution by Geography, 2021, 2024 and 2035
  • Table 25.52 mRNA Synthesis and Manufacturing Market in North America, till 2035 (USD Billion)
  • Table 25.53 mRNA Synthesis and Manufacturing Market in Europe, till 2035 (USD Billion)
  • Table 25.54 mRNA Synthesis and Manufacturing Market in Asia-Pacific, till 2035 (USD Billion)
  • Table 25.55 mRNA Synthesis and Manufacturing Market in Latin America, till 2035 (USD Billion)
  • Table 25.56 mRNA Synthesis and Manufacturing Market in Middle East and North Africa, till 2035 (USD Billion)
  • Table 25.57 mRNA Synthesis and Manufacturing Market in Rest of the World, till 2035 (USD Billion)

List of Figures

  • Figure 2.1 Research Methodology: Project Methodology
  • Figure 2.2 Research Methodology: Forecast Methodology
  • Figure 2.3 Research Methodology: Robust Quality Control
  • Figure 2.4 Research Methodology: Key Market Segmentations
  • Figure 3.1 Lessons Learnt from Past Recessions
  • Figure 4.1 Executive Summary: mRNA Custom Synthesis Service Providers Market Landscape
  • Figure 4.2 Executive Summary: mRNA Contract Manufacturing Service Providers Market Landscape
  • Figure 4.3 Executive Summary: mRNA Synthesis Kits Market Landscape
  • Figure 4.4 Executive Summary: Partnership and Collaborations
  • Figure 4.5 Executive Summary: Big Pharma Initiatives
  • Figure 4.6 Executive Summary: Market Forecast and Opportunity Analysis
  • Figure 5.1 Structure of mRNA
  • Figure 5.2 Evolution of mRNA Vaccines
  • Figure 5.3 Steps involved in mRNA Synthesis
  • Figure 6.1 mRNA Custom Synthesis Service Providers: Distribution by Year of Establishment
  • Figure 6.2 mRNA Custom Synthesis Service Providers: Distribution by Company Size
  • Figure 6.3 mRNA Custom Synthesis Service Providers: Distribution by Location of Headquarters
  • Figure 6.4 mRNA Custom Synthesis Service Providers: Distribution by Type of Service Offered
  • Figure 6.5 mRNA Custom Synthesis Service Providers: Distribution by Starting Material
  • Figure 6.6 mRNA Custom Synthesis Service Providers: Distribution by Structural Modification
  • Figure 6.7 mRNA Custom Synthesis Service Providers: Distribution by Type of Purification Method
  • Figure 6.8 mRNA Custom Synthesis Service Providers: Distribution by Application Area
  • Figure 6.9 mRNA Custom Synthesis Service Providers: Distribution by Scale of Operation
  • Figure 7.1 Company Competitiveness Analysis: mRNA Custom Synthesis Service Providers based in North America
  • Figure 7.2 Company Competitiveness Analysis: Benchmarking of mRNA Custom Synthesis Service Providers in North America
  • Figure 7.3 Company Competitiveness Analysis: mRNA Custom Synthesis Service Providers based in Europe
  • Figure 7.4 Company Competitiveness Analysis: Benchmarking of mRNA Custom Synthesis Service Providers in Europe
  • Figure 7.5 Company Competitiveness Analysis: mRNA Custom Synthesis Service Providers based in Asia-Pacific
  • Figure 7.6 Company Competitiveness Analysis: Benchmarking of mRNA Custom Synthesis Service Providers in Asia-Pacific
  • Figure 9.1 mRNA Contract Manufacturing Service Providers: Distribution by Year of Establishment
  • Figure 9.2 mRNA Contract Manufacturing Service Providers: Distribution by Company Size
  • Figure 9.3 mRNA Contract Manufacturing Service Providers: Distribution by Location of Headquarters (Region)
  • Figure 9.4 mRNA Contract Manufacturing Service Providers: Distribution by Location of Headquarters (Country)
  • Figure 9.5 mRNA Contract Manufacturing Service Providers: Distribution by Location of Manufacturing Facilities
  • Figure 9.6 mRNA Contract Manufacturing Service Providers: Distribution by Type of Additional Services
  • Figure 9.7 mRNA Contract Manufacturing Service Providers: Distribution by Type of Product Manufactured
  • Figure 9.8 mRNA Contract Manufacturing Service Providers: Distribution by Scale of Operation
  • Figure 10.1 Company Competitiveness Analysis: mRNA Contract Manufacturing Service Providers based in North America
  • Figure 10.2 Company Competitiveness Analysis: Benchmarking of mRNA Contract Manufacturing Service Providers in North America
  • Figure 10.3 Company Competitiveness Analysis: mRNA Contract Manufacturing Service Providers based in Europe
  • Figure 10.4 Company Competitiveness Analysis: Benchmarking of mRNA Contract Manufacturing Service Providers in Europe
  • Figure 10.5 Company Competitiveness Analysis: mRNA Contract Manufacturing Service Providers based in Asia-Pacific
  • Figure 10.6 Company Competitiveness Analysis: Benchmarking of mRNA Contract Manufacturing Service Providers in Asia-Pacific
  • Figure 12.1 mRNA Synthesis Kits: Distribution by Kit Components
  • Figure 12.2 mRNA Synthesis Kits: Distribution by Type of Enzyme
  • Figure 12.3 mRNA Synthesis Kits: Distribution by Type of Enzyme Mix Used
  • Figure 12.4 mRNA Synthesis Kits: Distribution by mRNA Component Modified
  • Figure 12.5 mRNA Synthesis Kits: Distribution by Number of Reaction
  • Figure 12.6 mRNA Synthesis Kits: Distribution by Yield Per Reaction
  • Figure 12.7 mRNA Synthesis Kits: Distribution by Reaction Run-time
  • Figure 12.8 mRNA Synthesis Kits: Distribution by Kit Price
  • Figure 12.9 Most Active Players: Distribution by Number of Kits Offered
  • Figure 12.10 mRNA Synthesis Kit Providers: Distribution by Year of Establishment
  • Figure 12.11 mRNA Synthesis Kit Providers: Distribution by Company Size
  • Figure 12.12 mRNA Synthesis Kit Providers: Distribution by Location of Headquarters
  • Figure 13.1 Product Competitiveness Analysis: mRNA Synthesis Kits
  • Figure 15.1 Partnerships and Collaborations: Distribution by Year of Partnership
  • Figure 15.2 Partnerships and Collaborations: Distribution by Type of Partnership
  • Figure 15.3 Partnerships and Collaborations: Distribution by Year and Type of Partnership
  • Figure 15.4 Partnerships and Collaborations: Distribution by Type of Product (Broad)
  • Figure 15.5 Partnerships and Collaborations: Distribution by Type of Product (Specific)
  • Figure 15.6 Partnerships and Collaborations: Distribution by Type of Partner
  • Figure 15.7 Most Active Players: Distribution by Number of Partnerships
  • Figure 15.8 Partnerships and Collaborations: Intercontinental and Intracontinental Deals
  • Figure 15.9 Partnerships and Collaborations: Local and International Deals
  • Figure 16.1 mRNA Drug Developers: Likely Partners based in North America
  • Figure 16.2 mRNA Drug Developers: Most Likely Partners based in North America
  • Figure 16.3 mRNA Drug Developers: Likely Partners based in Europe
  • Figure 16.4 mRNA Drug Developers: Most Likely Partners based in Europe
  • Figure 16.5 mRNA Drug Developers: Likely Partners based in Asia-Pacific and Rest of the World
  • Figure 16.6 mRNA Drug Developers: Most Likely Partners based in Asia-Pacific and Rest of the World
  • Figure 17.1 Benchmarking of Big Pharma Players: Spider Web Analysis
  • Figure 17.2 Big Pharma Players: Distribution by Portfolio Diversity
  • Figure 17.3 Big Pharma Players: Distribution by Therapeutic Diversity
  • Figure 17.4 Big Pharma Players: Distribution by Number of Initiatives
  • Figure 18.1. Market Trends and Outlook: Key Growth Drivers
  • Figure 18.2. Market Trends and Outlook: Market Restraints
  • Figure 18.3. Market Trends and Outlook: Opportunities
  • Figure 18.4. Market Trends and Outlook: Challenges
  • Figure 19.1 Global mRNA Synthesis and Manufacturing Market, Historical Trends (2021-2023) and Forecasted Estimates (2024-2035)
  • Figure 20.1 mRNA Synthesis and Manufacturing Market: Distribution by Type of Product, 2021, 2024 and 2035
  • Figure 20.2 mRNA Synthesis and Manufacturing: Market for Drug Substances (APIs), till 2035
  • Figure 20.3 mRNA Synthesis and Manufacturing Market for Drug Products (FDFs), till 2035
  • Figure 21.1 mRNA Synthesis and Manufacturing Market: Distribution by Application Area, 2021, 2024 and 2035
  • Figure 21.2 mRNA Synthesis and Manufacturing Market for mRNA-based Vaccines, till 2035
  • Figure 21.3 mRNA Synthesis and Manufacturing Market for mRNA-based Therapeutics, till 2035
  • Figure 22.1 mRNA Synthesis and Manufacturing Market: Distribution by Therapeutic Area, 2021, 2024 and 2035
  • Figure 22.2 mRNA Synthesis and Manufacturing Market for Infectious Diseases, till 2035
  • Figure 22.3 mRNA Synthesis and Manufacturing Market for Oncological Disorders, till 2035
  • Figure 22.4 mRNA Synthesis and Manufacturing Market for Other Disorders, till 2035
  • Figure 23.1 mRNA Synthesis and Manufacturing Market: Distribution by Geography, 2021, 2024 and 2035
  • Figure 23.2 mRNA Synthesis and Manufacturing Market in North America, till 2035
  • Figure 23.3 mRNA Synthesis and Manufacturing Market in Europe, till 2035
  • Figure 23.4 mRNA Synthesis and Manufacturing Market in Asia-Pacific, till 2035
  • Figure 23.5 mRNA Synthesis and Manufacturing Market in Rest of the World, till 2035