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市場調查報告書
商品編碼
1479826
mRNA 合成與製造市場:產業趨勢與 2035 年全球預測 - 依產品類型、應用領域、治療領域和關鍵區域mRNA Synthesis and Manufacturing Market : Industry Trends and Global Forecasts, till 2035 - Distribution by Type of Product (Drug Substances and Drug Products ), Application Area, Therapeutic Area and Key Geographical Regions |
核糖核酸 (RNA) 是一種普遍存在於所有活細胞中的分子,負責將遺傳訊息轉化為蛋白質,對多種細胞過程非常重要。RNA 有多種形式,包括信使 RNA (mRNA)、轉移 RNA (tRNA) 和核醣體 RNA (rRNA),而 mRNA 正在成為現代醫療保健中的重要治療工具。mRNA 上的遺傳密碼被翻譯成胺基酸並加工成功能性蛋白質。自COVID-19大流行以來,mRNA疫苗和治療藥物的生產引起了極大關注,並正在成為不僅針對COVID-19而且針對腫瘤疾病、傳染病和遺傳疾病等多種疾病的下一代藥物類別。是。
然而,製造 mRNA 療法和疫苗是一個複雜且昂貴的過程,需要專門的知識和能力。因此,mRNA 療法和疫苗的開發者正在積極尋求解決方案來克服這些課題。外包已成為 mRNA 開發商的一個有吸引力的選擇,為這些障礙提供了潛在的解決方案。未來,由於慢性疾病的增加、基因治療需求的增加、基於RNA的療法在臨床和商業階段的成熟以及技術的進步,預計mRNA合成和製造市場將穩定成長。
該報告考察了全球 mRNA 合成和製造市場,並依產品類型、應用領域、治療領域、地區以及參與市場的公司概況提供了市場概況、趨勢。
mRNA Synthesis and Manufacturing Market (3rd Edition): Industry Trends and Global Forecasts, till 2035 - Distribution by Type of Product (Drug Substances (APIs) and Drug Products (FDFs)), Application Area (mRNA-based Vaccines and mRNA-based Therapeutics), Therapeutic Area (Infectious Diseases, Oncological Disorders and Other Disorders) and Key Geographical Regions (North America, Europe, Asia-Pacific and Rest of the World)
The mRNA Synthesis and Manufacturing Market is valued at USD 1.06 billion in 2024.
Ribonucleic acid (RNA) is a ubiquitous molecule found in all the living cells, which is responsible for translating genetic information into proteins which is important for various cellular processes. RNA comes in different forms, including messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA), with mRNA emerging as a prominent therapeutic modality in modern healthcare. mRNA is a single-stranded molecule that carries genetic information from DNA to produce proteins. This genetic code on mRNA is translated into amino acids, which are then processed into functional proteins. Since the onset of the COVID-19 pandemic, mRNA vaccine and therapeutic manufacturing have garnered considerable attention, emerging as a next-generation drug class not only for COVID-19 but also for various other conditions like oncological disorders, infectious diseases, and genetic disorders.
However, producing mRNA therapeutics and vaccines is a complex and expensive process which demands specialized expertise and capabilities. Consequently, developers of mRNA therapeutics and vaccines are actively exploring solutions to overcome these challenges. Outsourcing has emerged as an attractive option for mRNA developers, offering potential solutions to these hurdles. Looking ahead, with the increasing prevalence of chronic diseases, growing demand for gene therapy, maturation of RNA-based therapies in clinical and commercial stages, and advancements in technology, we anticipate robust growth in the mRNA synthesis and manufacturing market.
Key Market Segments
Type of Product
Drug Substance (APIs)
Drug Product (FDFs)
Application Area
mRNA-based Vaccines
mRNA-based Therapeutics
Therapeutic Area
Infectious Diseases
Oncological Disorders
Other Diseases
Key Geographical Regions
North America
Europe
Asia-Pacific
Rest of the World
Research Coverage:
An overview of structure and the historical evolution of mRNA vaccines. A comprehensive discussion pertaining the information on the synthetic mRNA production, both chemically and in vitro, and its applications across various therapeutic area. Further, it features the challenges associated with the synthesis and manufacturing processes of mRNA are outlined as well. Further, the module delves into the commonly outsourced manufacturing operations and their advantages.
A comprehensive evaluation of mRNA custom synthesis service providers, considering several relevant parameters, such as year of establishment, company size (measured by the number of employees), headquarters location (North America, Europe, and Asia Pacific), types of services offered (such as mRNA modification, purification, scale-up, process development, and fill/finish), starting material (plasmid DNA, mRNA sequence, PCR fragments), structural modification (5' modification, 3' modification, ribonucleotide base modification, and others), purification methods (chromatography, electrophoresis, desalting/precipitation, and others), application areas (vaccine production, therapeutic production, and others), and scale of operation (preclinical/research, clinical, and commercial). Additionally, the chapter includes information on the length of the mRNA manufactured and the production capacity of the stakeholders.
An in-depth competitiveness analysis of mRNA custom synthesis service providers across key geographical regions. This analysis takes into account the supplier strength, including years of experience and company size, as well as service strength, which encompasses the number and types of services offered, modifications, scale of operation, compliance with Good Manufacturing Practices (GMP), and application areas.
A thorough assessment of mRNA contract manufacturing service providers, considering various pertinent parameters. These parameters include the year of establishment, company size (measured by the number of employees), headquarters location (North America, Europe, and Asia Pacific), location of manufacturing facilities, types of additional services offered (such as formulation development, analytical testing, process development, mRNA purification, fill / finish, scale-up, regulatory support, and others), type of product manufactured (drug substances (APIs) and drug products (FDFs)), and scale of operation (preclinical/research, clinical, and commercial).
A thorough company competitiveness analysis of mRNA contract manufacturing service providers across key geographical regions, focusing on the supplier strength and service portfolio strength. Supplier strength is assessed based on years of experience and company size, while service portfolio strength considers factors such as the number of facilities, type of products manufactured, variety of services offered, and scale of operation.
A comprehensive evaluation of the current market landscape of mRNA synthesis kits, considering various pertinent parameters. These parameters include kit components (such as enzyme mix, reagents, buffer, etc.), types of enzymes utilized (including capping enzyme and tailing enzyme), enzyme mix variants (such as T7 polymerase, SP6 polymerase, and T3 polymerase), mRNA components modified (cap, base, and tail), number of reactions per kit (ranging from 5 to 50 reactions), yield per reaction (categorized by microgram ranges), reaction run time (classified by duration), and kit price (grouped into price ranges). Furthermore, the chapter provides an extensive analysis of mRNA synthesis kit providers, offering insights into their year of establishment, company size (measured by employee count), headquarters location, and the most active players in terms of the number of mRNA synthesis kits offered.
A detailed analysis of mRNA synthesis kits, focusing on the supplier strength and product attributes. Supplier strength is evaluated based on years of experience and company size, while product strength is assessed based on the number of kit components, types of enzymes included, types of mRNA components modified, yield per reaction, number of reactions per kit, reaction run time, and kit price.
Detailed company profiles of the top mRNA manufacturing companies based on their robust service offerings. Each profile includes a concise company overview, encompassing establishment year, headquarters location, employee count, and notable executives. Additionally, it delves into their mRNA synthesis and manufacturing services, recent advancements, and well-informed future perspectives. Further, the leading service providers in mRNA synthesis and manufacturing, profiles of other noteworthy players have been included, featuring company background and mRNA synthesis and manufacturing service details.
Comprehensive profiles of leading mRNA synthesis kit providers have been curated, selected for their robust product portfolios. Each profile provides a succinct company overview, coupled with details on their mRNA synthesis kits portfolio.
An exhaustive examination of partnerships formed among stakeholders within this industry between 2019 and 2023, taking into account various parameters. These parameters include the year of partnership, nature of partnership, product type, partner type, and identification of the most prolific players based on the quantity of partnerships forged. Furthermore, the analysis offers insights into the regional distribution of the companies engaged in these collaborations.
A comprehensive analysis of over 35 developers of mRNA-based therapeutics and vaccines, identified for potential partnerships with mRNA contract manufacturing service providers. These developers have been carefully shortlisted based on various parameters including the strength of the developer (evaluated through company experience), company size (measured by the number of employees), pipeline robustness (assessed by the quantity of mRNA-based drugs in the pipeline), highest development phase attained, therapeutic focus, route of administration, and the type of candidates under development.
An comprehensive examination of the diverse mRNA-focused initiatives undertaken by major pharmaceutical companies, selected based on their 2023 revenues. This review highlights trends across multiple parameters, including the quantity of initiatives, initiation year, purpose, type, and therapeutic focus of each initiative.
A detailed analysis on the factors influencing the growth of the mRNA synthesis and manufacturing market. This study includes the identification and examination of key drivers propelling market expansion, potential restraints hindering growth, emerging opportunities for market advancement, and existing challenges that may impede progress.
In-depth forecast analysis of the mRNA synthesis and manufacturing market to estimate both the current market size and the future opportunities up to the year 2035. Utilizing multiple parameters such as anticipated adoption trends and rigorous primary validations, we have derived an informed estimate of the market evolution during the forecast period from 2024 to 2035. Furthermore, this module outlines the likely distribution of the current and forecasted opportunities within the mRNA synthesis and manufacturing market. To enhance the robustness of our model and to accommodate future uncertainties, we have developed three forecast scenarios: conservative, base, and optimistic. These scenarios represent different trajectories of industry growth, providing a comprehensive perspective on potential market developments.
Detailed projections have been formulated for the current and future mRNA synthesis and manufacturing market, categorized by type of product, encompassing both drug substances and drug products. These projections offer comprehensive insights into the anticipated growth trajectories, market sizes, and emerging trends for each product type within the mRNA synthesis and manufacturing landscape.
Detailed projections of the current and future mRNA synthesis and manufacturing market across application area, such as mRNA-based vaccines and mRNA-based therapeutics.
Detailed projections of the current and future mRNA synthesis and mRNA manufacturing market across therapeutic area, such as infectious diseases, oncological disorders and other disorders.
Detailed projections of the current and future mRNA synthesis and manufacturing market across key geographies, such as North America, Europe, Asia-Pacific, and Rest of the World.
Key Benefits of Buying this Report
The report offers market leaders and newcomers valuable insights into revenue estimations for both the overall market and its sub-segments.
Stakeholders can utilize the report to enhance their understanding of the competitive landscape, allowing for improved business positioning and more effective go-to-market strategies.
The report provides stakeholders with a pulse on the mRNA Synthesis and Manufacturing Market, furnishing them with essential information on significant market drivers, barriers, opportunities, and challenges.
Leading Market Companies
Aldevron
APExBIO
Aurigene Pharmaceutical Services
Biomay
Curia
eTheRNA
Enzynomics
Eurogentec
Genscript
Jena Bioscience
Merck KGaA
New England Biolabs
Vernal Biosciences
ST Pharm
Thermo Fisher Scientific
TriLink BioTechnologies
WuXi Biologics