3D 細胞培養市場規模、佔有率、成長分析、按產品、按應用、按最終用戶、按地區 - 行業預測，2024-2031 年

2022年3D細胞培養市場規模為13億美元，從2023年的15.4億美元成長到2031年的58.5億美元，預計複合年成長率為18.2%。

3D 系統電子學的進步已經超越了傳統技術，是藥物研究、臨床前測試、組織工程和基礎科學的基礎。透過讓細胞在3D上生長和相互作用，3D 細胞培養物可以與細胞外基質相互作用，使它們比平面 2D 培養物更俱生理相關性。這種多樣性包括各種模型，包括球體、類器官、生物列印細胞模型和晶片上器官模型，每種模型都有獨特的優點。球體在保持其遺傳組成的同時呈現球形形狀，由幹細胞製成的類器官表現出成熟的功能，器官晶片模仿具有動態流體流動的器官結構。在慢性疾病增加和捐贈者短缺的背景下，迫切需要替代醫學來替代器官移植，人們對再生醫學和組織工程的興趣日益濃厚，3D細胞培養系統正在開發用於移植和移植的類器官。分析。此類系統的市場正在經歷創新，例如 3D BioFibR 於 2023 年 6 月推出的膠原蛋白纖維產品 CollaFibR 3D Scaffold 和 μCollaFibR，增強了 3D 細胞培養的功能，我們正在見證新產品的推出帶來的成長。此外，旨在擴大癌症治療藥物篩檢的 3D 體外服務的合作夥伴關係，例如 Charles River Laboratories 和 CELLphenomics 於 2023 年 12 月的合作，將推動市場擴張，這反映了不斷成長的需求和協作努力。

目錄

介紹

• 這項研究的目的
• 定義
• 市場範圍

調查方法

• 資訊採購
• 二手資料來源和主要資料來源
• 市場規模預測
• 市場假設與限制

執行摘要

• 市場概況展望
• 供需趨勢分析
• 按細分市場的機會分析

市場動態及展望

• 市場動態
  • 促進因素
  • 機會
  • 抑制因素
  • 任務
• 波特的分析

主要市場考察

• 技術分析
• 價格分析
• 專利分析
• 技術分析
• 客戶和購買標準分析
• 市場生態系統
• 監管環境
• 創新矩陣
• 主要投資分析
• 關鍵成功因素
• 競爭程度

3D 細胞培養市場：依技術分類

• 市場概況
• 基於支架的 3D 細胞培養
  • 水凝膠
  • 天然和合成水凝膠
  • 固體的鷹架
  • 微圖案表面
  • 其他
• 無支架 3D 細胞培養
  • 低附件
  • 懸滴板
  • 3D反應器
  • 3D 培養皿
  • 其他
• 利用磁性和生物列印進行 3D 細胞培養
• 微流體器官晶片模型

3D 細胞培養市場：依應用分類

• 市場概況
• 癌症研究
• 幹細胞研究
• 藥物發現和毒性測試
• 組織工程與再生醫學

3D 細胞培養市場：依最終用途分類

• 市場概況
• 生技/製藥公司
• 合約研究實驗室
• 化妝品產業
• 學術/研究機構
• 其他

3D 細胞培養市場：按地區分類的規模

• 市場概況
• 北美洲
  • 美國
  • 加拿大
• 歐洲
  • 德國
  • 西班牙
  • 法國
  • 英國
  • 義大利
  • 其他歐洲國家地區
• 亞太地區
  • 中國
  • 印度
  • 日本
  • 韓國
  • 其他亞太地區
• 拉丁美洲
  • 巴西
  • 其他拉丁美洲地區
• 中東和非洲 (MEA)
  • 海灣合作理事會國家
  • 南非
  • 其他中東/非洲地區

競爭格局

• 前5名企業對比
• 主要企業市場定位（2023年）
• 主要市場參與者所採取的策略
• 近期市集活動
• 主要企業市場佔有率（2023年）

主要企業簡介

• Thermo Fisher Scientific US
• Merck KGaA
• Corning Incorporated
• Becton, Dickinson And Company
• Lonza
• 3d Biotek LLC
• Advanced Biomatrix, Inc
• Avantor, Inc
• Merck & Co., Inc.
• Tecan Trading AG
• Reprocell Inc
• Emulate
• Synthecon Incorporated
• Insphero AG
• Kirkstall Ltd.
• Promocell GmBh
• UPM Biomedicals
• CN Bio Innovations Ltd
• Synvivo Inc.
• Amsbio

3D Cell Culture Market size was valued at USD 1.3 billion in 2022 and is poised to grow from USD 1.54 billion in 2023 to USD 5.85 billion by 2031, growing at a CAGR of 18.2% during the forecast period (2024-2031).

3D system electronics have become fundamental in drug research, preclinical testing, tissue engineering, and basic sciences, surpassing traditional technologies due to their advancements. By allowing cells to grow and interact in three dimensions, 3D cell cultures enable engagement with the extracellular matrix, enhancing physiological relevance compared to flat 2D cultures. This diversity encompasses various models like spheroids, organoids, bioprinted cell models, and organs-on-chips, each offering unique benefits. Spheroids exhibit spherical shape while maintaining genetic composition, organoids from stem cells exhibit mature function, and organs-on-chips mimic organ structures with dynamic fluid flow. The pressing need for alternatives to organ transplantation, driven by escalating chronic diseases and donor shortages, has spurred interest in regenerative medicine and tissue engineering, where 3D cell culture systems excel in organoid culture and tissue construct development for transplantation and drug response analysis. The market for such systems is witnessing growth with the introduction of innovative products, exemplified by 3D BioFibR's launch of collagen fiber products, CollaFibR 3D scaffold and μCollaFibR, in June 2023, enhancing 3D cell culture capabilities. Additionally, partnerships like that between Charles River Laboratories and CELLphenomics in December 2023, aimed at expanding 3D in vitro services for drug screening in cancer therapy, reflect the increasing demand and collaborative efforts driving market expansion.

Top-down and bottom-up approaches were used to estimate and validate the size of the 3D Cell Culture market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

3D Cell Culture Market Segmental Analysis

3D Cell Culture Market is segmented by Product, Application, End User and region. Based on Product, the market can be segmented into Scaffold-based, Scaffold-free, Bioreactors, and others. Based on Application, the market is segmented into Cancer Research, Stem Cell Research & Tissue Engineering, and Others. Based on End User, the market is segmented into Biotechnology and Pharmaceutical Companies, Academic & Research Institutes, and Others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Drivers of the 3D Cell Culture Market

The burgeoning influence of 3D cell culture on advancing regenerative medicine is poised to revolutionize the field, offering a groundbreaking approach that fosters the development of intricate tissue structures mirroring natural environments. This pioneering method enables in-depth exploration of tissue regeneration and engineering, propelling it to the forefront of medical research. As regenerative medicine gains traction as a new paradigm in healthcare, demand for these sophisticated cell culture technologies, such as bio-3D, continues to surge. Consequently, this emerging technology drives growth in the 3D cell culture industry by providing highly specialized tools for researchers and clinicians to comprehend and implement regenerative therapies effectively.

Restraints in the 3D Cell Culture Market

The adoption of 3D cell cultures marks a significant advancement over traditional monolayer cultures, demanding the use of advanced cell culture resources, consequently driving up direct expenses associated with experiments. While offering numerous advantages, the implementation of 3D cell cultures results in higher costs due to the elevated prices of 3D scaffolds and materials compared to those utilized in 2D cell cultures. Especially in drug discovery efforts, where numerous experiments are crucial, employing 3D cell culture methods can inflate drug development expenses substantially, potentially making certain avenues financially unfeasible.

Market Trends of the 3D Cell Culture Market

Cutting-edge advancements in cell culture technologies have led to the rapid evolution of organ-on-a-chip and microfluidic systems, providing increasingly intricate 3D cell culture environments. These innovative platforms empower researchers to mimic inter-organ and tissue interactions with heightened accuracy. For instance, in December 2022, Emulate, Inc., launched the Emulate Chip-A1(TM) Accessible Chip through an early access program. This latest iteration expands upon the capabilities of the original Chip-S1, faithfully reproducing tissue-vascular interfaces with relevant biomechanical stimuli such as stretch and flow. The Chip-A1(TM) allows users to cultivate thicker tissues within the epithelial culture chamber and employ a broader range of drug treatment techniques, including topical or aerosolized applications, thereby augmenting versatility and experimentation capabilities.

Table of Contents

Introduction

• Objectives of the Study
• Definitions
• Market Scope

Research Methodology

• Information Procurement
• Secondary & Primary Data Sources
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Market Overview Outlook
• Supply Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Dynamics
  • Drivers
  • Opportunities
  • Restraints
  • Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of Substitute Products
  • Bargaining Power of Buyers
  • Threat of New Entrants
  • Bargaining Power of Suppliers

Key Market Insights

• Technology Analysis
• Pricing Analysis
• Patent Analysis
• Technology Analysis
• Customer & Buying Criteria Analysis
• Ecosystem of the Market
• Regulatory Landscape
• Innovation Matrix
• Top Investment Analysis
• Key Success Factor
• Degree of Competition

3D Cell Culture Market by Technology

• Market Overview
• Scaffold-based 3D Cell Cultures
  • Hydrogels
  • Natural & Synthetic Hydrogels
  • Solid Scaffolds
  • Micropatterned Surfaces
  • Others
• Scaffold-free 3D Cell Cultures
  • Low Attachment Plates
  • Hanging Drop Plates
  • 3d Bioreactors
  • 3d Petri Dishes
  • Others
• Magnetic & Bioprinted 3d Cell Cultures
• Microfluidic Organ-on-a-Chip Models

3D Cell Culture Market by Application

• Market Overview
• Cancer Research
• Stem Cell Research
• Drug Discovery & Toxicology Testing
• Tissue Engineering & Regenerative Medicine

3D Cell Culture Market by End Use

• Market Overview
• Biotechnology and Pharmaceutical Companies
• Contract Research Laboratories
• Cosmetic Industry
• Academic & Research Institutes
• Others

3D Cell Culture Market Size by Region

• Market Overview
• North America
  • USA
  • Canada
• Europe
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America
  • Brazil
  • Rest of Latin America
• Middle East & Africa (MEA)
  • GCC Countries
  • South Africa
  • Rest of MEA

Competitive Landscape

• Top 5 Player Comparison
• Market Positioning of Key Players, 2023
• Strategies Adopted by Key Market Players
• Recent Activities in the Market
• Key Companies Market Share (%), 2023

Key Company Profiles

• Thermo Fisher Scientific US
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Corning Incorporated
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Becton, Dickinson And Company
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Lonza
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• 3d Biotek LLC
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Advanced Biomatrix, Inc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Avantor, Inc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck & Co., Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Tecan Trading AG
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Reprocell Inc
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Emulate
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Synthecon Incorporated
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Insphero AG
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Kirkstall Ltd.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Promocell GmBh
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• UPM Biomedicals
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• CN Bio Innovations Ltd
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Synvivo Inc.
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Amsbio
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments