市場調查報告書
商品編碼
1284285
到 2028 年蛋白質純化和分離市場預測 - 按產品、技術、應用、最終用戶和地區分列的全球分析Protein Purification and Isolation Market Forecasts to 2028 - Global Analysis By Product, Technology, Application, End User and By Geography |
根據Stratistics MRC,2022年全球蛋白質純化分離市場規模將達到82.4億美元,預計2028年將達到174億美元,預計複合年增長率為13.26% 2020年。
蛋白質純化是利用物理差異從細胞、組織和生物體的複雜混合物中去除蛋白質的過程。 蛋白質純化需要獲得大量純淨的功能性蛋白質。 為了獲得所需的蛋白質,該過程將蛋白質與混合物中的非蛋白質成分分離。 它們主要用於對蛋白質結構、功能和相互作用進行分類。 親和層析、免疫沉澱、蛋白質組學、□分析等是一些常用的蛋白質純化和分離技術。
根據Research America 2022年1月發布的一份報告,2020年生物製藥企業將投入約1222.04億美元,而2019年將投入約1109.32億美元用於研發。 因此,這些事實有望推動該國的市場增長。
市場擴張的主要驅動力之一是發現新型配體(例如基於蛋白質的治療化合物)的重要性與日俱增。 全球蛋白質純化和分離市場受到對用於快速篩選、製備、純化和富集蛋白質樣品的快速純化試劑盒不斷增長的需求的推動。 此外,由於各種因素,例如公共和私人研究機構增加研發資金以及擴大對基於結構的藥物設計的研究,市場有望擴大。
蛋白質純化和分離技術通常需要特殊的工具、試劑和人力資源,導致總體成本高昂。 對於資源有限的研究人員和機構來說,獲得此類技術的機會可能會受到限制。 此外,蛋白質純化和分離非常耗時,需要許多步驟,例如細胞裂解、層析和過濾。 蛋白質純化可能耗時、低效且不可擴展。
政府增加研發投資以及鼓勵研發增長和擴張的計劃將使製藥和生物技術行業受益。 額外的好處包括補貼、法規和稅收優惠。 對生物標誌物特異性分子研發的大量投資使製藥行業成為蛋白質純化和分離產品的高利潤市場。
蛋白質純化和分離過程可能需要遵守監管要求和質量標準,尤其是在生物技術和製藥應用中。 為滿足這些要求,整個過程可能會變得更加複雜和昂貴。 此外,還沒有能夠成功分離和純化所有類型蛋白質的純化技術。 不同的蛋白質可能需要以特定的方式進行純化以適應它們的特性,從而使過程更加複雜和多變。
蛋白質純化和分離市場受到 COVID-19 供應鏈中斷和交付製造用於蛋白質純化和分離的試劑盒、試劑和消耗品所需的關鍵材料的延遲的負面影響。 由於卡車運輸瓶頸和港口檢查、許多國家的出口禁令、運營中的製造設施減少以及運輸和製造貨物的醫療保健,大流行導致關鍵貨物的交付延誤。這給市場帶來了重大挑戰,例如工人短缺。 結果,這種情況最初阻礙了市場的增長。 然而,近年來隨著蛋白質純化和分離技術被用於分析和研究新出現的急性呼吸系統綜合症冠狀病毒 (SARS-CoV-2),需求有所增加。
在預測期內,耗材部分預計將在蛋白質純化和分離領域佔據最大的市場份額。 該細分市場的巨大市場份額主要是由於耗材在蛋白質純化中的頻繁使用以及學術和醫學研究機構以及製藥公司等各種最終用戶對生物製藥開發的興趣日益濃厚。。
預計超濾部分在預測期內將呈現最高增長率。 超濾是一種用於去除液體中溶解的分子和非常小的顆粒的技術。 分子大小是分離的主要依據,但樣品的化學、分子和靜電特性也會影響過濾器的滲透性。 蛋白質和緩衝液組分通常使用超濾分離,用於緩衝液交換、濃縮和脫鹽。 超濾的優勢及其在蛋白質純化和分離中的廣泛應用是預測期內推動該細分市場增長的主要因素。
由於蛋白質純化市場的眾多參與者、研發基礎設施的發展以及蛋白質組學技術的發展,在預測期內,北美將繼續主導全球蛋白質純化市場。 北美市場對技術先進的蛋白質分離技術的需求也受到蛋白質-蛋白質相互作用研究、目標識別、藥物篩選、蛋白質治療、生物標誌物發現、疾病監測和診斷測試等應用領域改進的推動。
在預測期內,亞太地區預計增長良好。 該地區對蛋白質純化和分離解決方案的需求預計將受到政府在中國和印度等發展中國家建設醫療保健基礎設施的努力的推動。 此外,這些政府正在資助尖端純化和分離技術的開發。 此外,促進國內藥品生產和生物仿製藥大規模生產的努力也有助於擴大市場。
2022 年 6 月,默克和馬利肯理論化學中心合作開展了一個機器學習項目。 這項為期三年的合作將側重於開髮用於計算化學建模的新工具和新分子表示。
2022 年 4 月,Thermo Fisher Scientific 與 Matrix Clinical Trials 合作加強了其臨床研究解決方案。 服務科學的全球領導者 Thermo Fisher Scientific 旗下的 PPD 臨床研究業務與 Matrix Medical Network 提供的 Matrix Clinical Trials 將合作開展臨床試驗,以創新的分散式臨床試驗(DCT)解決方案提供給患者。
According to Stratistics MRC, the Global Protein Purification and Isolation Market is accounted for $8.24 billion in 2022 and is expected to reach $17.40 billion by 2028 growing at a CAGR of 13.26% during the forecast period. Protein purification is the process of removing proteins using physical differences from complex mixtures of cells, tissues, or organisms. Large amounts of functional protein with few impurities are sought after by the protein purification procedure. In order to obtain the desired protein, the process separates proteins from non-protein components in a mixture. They are primarily used to categorize the protein's structure, function, and interactions. Affinity chromatography, immunoprecipitation, proteomics, or enzyme assays are a few of the frequently employed techniques for protein purification and isolation.
According to the report published by the Research America in January 2022, the biopharmaceutical companies invested around USD 122,204 million in 2020, wheras in 2019 the investment was around USD 110,932 million in R&D. Therefore, such fact is anticipated to drive the growth of the market in the country.
One of the main factors fueling market expansion is the growing importance of discovering novel ligands, such as protein-based therapeutic compounds. The global protein purification and isolation market is being driven by the increasing demand for rapid purification kits to quickly screen, prepare, purify, and concentrate protein samples. The market is also expected to grow as a result of a number of factors, including increased funding from both public and private research organizations for R&D and expanding research in structure-based drug design.
Techniques for protein purification and isolation frequently require specialized tools, reagents, and personnel, which raises the overall cost. For researchers and institutions with limited resources, this may limit their access to these techniques. Additionally, the process of purifying and isolating proteins can be time-consuming and involve numerous steps, including cell lysis, chromatography, and filtration. Protein purification may be less effective and less scalable as a result of the drawn-out processes.
Increased government investments in R&D and programs fostering their growth and expansion benefit the pharmaceutical and biotechnology industries. Additionally, they offer benefits in the form of grants, regulations, and tax breaks. Due to the significant investments made in studying and creating molecules specific to biomarkers, the pharmaceutical industry is a very lucrative market for goods involving protein purification and isolation.
Regulatory requirements and quality standards may apply to the protein purification and isolation process, particularly when it is used in biotechnology or pharmaceutical applications. The process as a whole may become more complicated and expensive due to compliance with these requirements. Additionally, there isn't a purification technique that can successfully isolate and purify every kind of protein. The process becomes more complex and variable as a result of the potential need for different proteins to be purified using specific methods tailored to their individual characteristics.
The protein purification and isolation market was negatively impacted by the supply chain disruption caused by COVID-19 and the delay in the delivery of crucial goods needed for the production of the kits, reagents, and consumables used in protein purification and isolation. A pandemic presents the market with a number of significant challenges, such as trucking bottlenecks and port checkpoints that slow down deliveries of essential supplies, export bans imposed in many nations, a dearth of operational manufacturing facilities, and a shortage of healthcare workers to transport and produce goods. As a result, this situation initially prevented market growth. The use of protein purification and isolation techniques for analysis and research involving the ever-emerging acute respiratory syndrome coronavirus (SARS-CoV-2) has, however, led to an increase in demand in recent years.
During the forecast period, the consumables segment is anticipated to hold the largest market share for protein purification and isolation. The significant market share of this sector is primarily attributable to the frequent use of consumables for protein purification and the attention paid to the development of biopharmaceuticals by a variety of end users, including academic and medical research institutions and pharmaceutical firms.
Over the forecast period, the ultrafiltration segment is anticipated to grow at the highest rate. Ultrafiltration is a technique used to remove dissolved molecules and incredibly small particles from liquids. The size of the molecules serves as the main basis for separation, though the sample's chemical, molecular, or electrostatic properties may also have an impact on the filter's permeability. Proteins and buffer components are typically separated using ultrafiltration for buffer exchange, concentration, or desalination. Ultrafiltration's benefits and widespread use in protein purification and isolation are the primary factors driving the segment's growth over the forecast period.
The presence of numerous protein purification market players, a developed research and development infrastructure, and technological developments in the proteomics sector all contribute to North America's continued dominance of the global protein purification market over the forecast period. The demand for technologically advanced protein isolation technologies in the North American market is also being driven by improved application fields like protein-protein interaction studies, target identification, drug screening, protein therapeutics, biomarker discovery, disease monitoring, and diagnostic tests.
Over the forecast period, Asia-Pacific is anticipated to experience lucrative growth. The demand for protein purification and isolation solutions in this region is expected to be driven by government initiatives for the development of healthcare infrastructure in developing nations like China and India. Moreover, these governments are funding the creation of cutting-edge purification and isolation techniques. Additionally, initiatives promoting domestic pharmaceutical production and the high volume of biosimilar production contribute to the market's expansion.
Some of the key players profiled in the Protein Purification and Isolation Market include Abcam plc, Agilent Technologies, Inc., Bio-Rad Laboratories, Inc., Danaher, G.E. Healthcare Life Sciences, Kamada Ltd., Lanleys International Inc., Leaf Expression Systems, Major Science, Merck KGaA, MNPHARM, Mtibio, Noble Life Sciences, Inc., Norgen Biotek Corporation, Promega Corporation, Qiagen N.V., Sigma-Aldrich Corporation, Takara Bio Inc and Thermo Fischer Scientific, Inc.
In June 2022, Merck and Mulliken Center for Theoretical Chemistry Collaborated in Machine Learning Project. The three-year collaboration will focus on developing new tools for computational chemistry modeling and new molecular representations.
In April 2022, Thermo Fisher Scientific Enhanced Clinical Research Solutions in Collaboration with Matrix Clinical Trials. The PPD clinical research business of Thermo Fisher Scientific Inc., the world leader in serving science, and Matrix Clinical Trials, a Matrix Medical Network offering, collaborated to bring clinical trials to patients with an innovative decentralized clinical trial (DCT) solution.
Note: Tables for North America, Europe, Asia Pacific, South America and Middle East & Africa Regions are also represented in the same manner as above.