市場調查報告書
商品編碼
1402015
聚合酶鍊式反應市場預測至 2030 年:按產品、應用、最終用戶和地區進行的全球分析Polymerase Chain Reaction Market Forecasts to 2030 - Global Analysis By Product, Application, End User and By Geography |
根據 Stratistics MRC 的數據,2023 年全球聚合酶鍊式反應市場規模為 89 億美元,預計在預測期內將以 11.5% 的複合年成長率成長,到 2030 年達到 191 億美元。
聚合酶鍊式反應是一種分子技術,透過體外擴增產生數百萬個特定 DNA 鏈的拷貝。 PCR 靈敏度很高,可以檢測微量 DNA。這在目標 DNA 濃度較低的應用中尤其有利,例如在某些疾病的早期階段或在分析法醫學樣本中的微量 DNA 時。
據印度醫學研究委員會 (ICMR) 稱,到 2027 年,印度的癌症病例將增加 12%。
基因檢測需求不斷成長
基因檢測需求的不斷成長是聚合酶鍊式反應市場的關鍵促進因素。基因測試涉及分析個體的 DNA,以識別遺傳變異、突變和基因表現模式。 PCR 透過擴增特定 DNA 序列以進行進一步分析,在此過程中發揮重要作用。此外,基因測試在那些對自己的血統感到好奇並想要探索自己的遺傳遺產的人中越來越受歡迎。因此,這些進步正在擴大 PCR 在基因檢測中的應用,並促進 PCR 市場的成長。
高成本
PCR 設備、試劑和消耗品的初始投資,加上對熟練人員的需求,增加了整體成本,特別是對於較小的診斷設施和實驗室。 PCR 設備的複雜性和持續的品管要求進一步增加了營運成本。此外,PCR 檢測的成本會對患者和醫療保健系統造成負擔,影響尖端診斷服務的負擔能力和公平分配。因此,高成本是市場拓展的主要障礙。
技術進步
即時 PCR 可以即時檢測和定量 PCR 擴增,在擴增過程中提供即時結果。這種即時監測可以實現更快、更準確的分析,使其在臨床診斷、基因檢測和研究等領域發揮作用。此外,PCR 設備技術的進步促進了更容易使用的自動化系統的開發。整合熱聚合酵素連鎖反應熱迴圈儀具有先進的溫度控制演算法和直覺的軟體介面,使包括研究人員、臨床醫生和技術人員在內的廣大用戶更容易使用 PCR。這些技術進步是加速市場需求的主要因素。
複雜性與專業知識
PCR技術涉及的各個步驟,包括引子設計、反應條件最佳化和資料分析,都需要一定程度的技術知識和訓練。 PCR 方案需要仔細設計和選擇專門特異性感興趣的 DNA 區域的引子。設計具有適當熔解溫度的引子、避免二級結構並最大限度地減少引子-二聚體相互作用是一項挑戰。進行聚合酶鏈反應所需的複雜性和技術專業知識是聚合酶鏈反應市場的抑制因素。
COVID-19 大流行嚴重影響了聚合酶鍊式反應市場的成長。臨床診斷細分市場需求的不斷成長對 PCR 市場產生了積極影響。醫學專家建議出現 COVID-19 症狀的人接受診斷測試,幾乎所有這些測試都使用 RT-PCR,因為當局不建議進行病毒培養測試。許多製藥和生物技術公司的研發部門都專注於尋找用於治療 COVID-19 的新分子和先導化合物。
預計試劑細分市場在預測期內將是最大的
試劑部分估計佔最大佔有率。 PCR 試劑包括多種化學物質,包括 DNA 聚合酶、引子、核苷酸和緩衝液,每種物質在反應中都扮演著特定的角色。 DNA聚合酶,例如Taq聚合酶,催化互補DNA鏈的合成,引子提供DNA擴增的起點。核苷酸作為新合成 DNA 鏈的建構模組,緩衝液維持酵素活性的最佳 pH 條件。為了確保 PCR 反應的準確性和效率,對高品質和可靠試劑的需求至關重要。
預計診斷中心細分市場在預測期內複合年成長率最高
預計診斷中心部門在預測期內將出現良好的成長。 PCR技術廣泛應用於診斷中心,用於檢測各種疾病,包括感染疾病、遺傳疾病和癌症。診斷中心利用 PCR 的高靈敏度和特異性來識別和量化特定的 DNA 或 RNA 序列,有助於早期、準確地診斷疾病。 PCR 的多功能性使診斷中心能夠提供廣泛的測試,有助於全面的患者照護。
在估計期間,北美佔據了最大的市場佔有率。高頻率的疾病、該地區重要參與企業的存在、有利的法規以及與醫療保健基礎設施進步相關的眾多政府舉措有助於該地區市場的成長。此外,患者對成功診斷的尖端產品的認知不斷增強也推動了成長。
由於感染疾病發病率上升、個人化醫療意識不斷增強以及醫療保健系統的改善,預計亞太地區將在預測期內實現有益成長。亞洲國家的研究活動不斷增加,特別是在基因組研究、腫瘤學和感染疾病研究領域。因此,PCR 作為一種準確、有效的 DNA 擴增方法已被廣泛應用。此外,該地區多樣化的人口和遺傳變異需要強大的分子診斷來實現個體化治療策略,這進一步推動了 PCR 市場的發展。
According to Stratistics MRC, the Global Polymerase Chain Reaction (PCR) Market is accounted for $8.9 billion in 2023 and is expected to reach $19.1 billion by 2030 growing at a CAGR of 11.5% during the forecast period. Polymerase Chain Reaction (PCR) is a molecular method for producing millions of copies of a particular DNA strand through in-vitro amplification. PCR is highly sensitive and can detect minute quantities of DNA. This is particularly advantageous in applications where the target DNA is present in low concentrations, such as in the early stages of certain diseases or when analyzing trace amounts of DNA in forensic samples.
According to Indian Council of Medical Research (ICMR), there will be a 12 percent rise in cancer cases in India by the 2027.
Rising demand for genetic testing
The rising demand for genetic testing has been a significant driver in the polymerase chain reaction (PCR) market. Genetic testing involves the analysis of an individual's DNA to identify genetic variations, mutations, and gene expression patterns. PCR plays a crucial role in this process by amplifying specific DNA sequences for further analysis. Additionally, genetic testing has gained popularity among individuals who are curious about their ancestry and want to explore their genetic heritage. Therefore, these advancements have expanded the applications of PCR in genetic testing, contributing to the growth of the PCR market.
High cost
The initial investment in PCR instruments, reagents, and consumables, coupled with the need for skilled personnel, contributes to the overall expense, especially for smaller diagnostic facilities and laboratories. The sophisticated nature of PCR equipment and the continuous requirement for quality control further add to the operational costs. Additionally, the expense of PCR tests may burden patients and healthcare systems, impacting the affordability and equitable distribution of cutting-edge diagnostic services. Therefore, high costs are a significant barrier to market expansion.
Technological advancements
Real-time PCR allows for the detection and quantification of PCR amplification in real-time, providing immediate results during the amplification process. This real-time monitoring enables faster and more precise analysis, making it valuable in fields such as clinical diagnostics, genetic testing, and research. Furthermore, advancements in PCR instrument technology have resulted in more user-friendly and automated systems. Integrated thermal cyclers with advanced temperature control algorithms and intuitive software interfaces have made PCR more accessible to a broader range of users, including researchers, clinicians, and technicians. These advancements in technology are a significant factor in accelerating market demand.
Complexity and technical expertise
A certain level of technical knowledge and training is required for the various steps involved in PCR techniques, which include primer design, reaction condition optimization, and data analysis. PCR protocols require careful design and selection of primers that specifically target the desired DNA regions. Designing primers with appropriate melting temperatures, avoiding secondary structures, and minimizing primer-dimer interactions can be challenging. The complexity and technical expertise required to perform polymerase chain reaction (PCR) act as restraints in the polymerase chain reaction (PCR) market.
The COVID-19 pandemic significantly impacted the polymerase chain reaction market growth. The growing demand in the clinical diagnostic market segment had a favourable effect on the PCR market. Healthcare professionals advised the population exhibiting COVID-19 symptoms to have a diagnostic test performed, and nearly all of these tests use RT-PCR since viral culture tests have not been recommended by the authorities. Most pharmaceutical and biotechnological companies were focusing on the research and development departments to identify new molecules or leads for the treatment of COVID-19.
The reagents segment is expected to be the largest during the forecast period
The reagents segment is estimated to hold the largest share. PCR reagents encompass a range of chemicals, including DNA polymerases, primers, nucleotides, and buffers, each playing a specific role in the reaction. DNA polymerases, such as Taq polymerase, catalyze the synthesis of complementary DNA strands, while primers provide the starting points for DNA amplification. Nucleotides serve as building blocks for the newly synthesized DNA strands, and buffers maintain the optimal pH conditions for enzymatic activity. The demand for high-quality and reliable reagents is paramount for the accuracy and efficiency of PCR reactions.
The diagnostic center segment is expected to have the highest CAGR during the forecast period
The diagnostic center segment is anticipated to have lucrative growth during the forecast period. PCR technology is extensively utilized in diagnostic centers for the detection of various diseases, including infectious agents, genetic disorders, and cancer. Diagnostic centers leverage PCR's high sensitivity and specificity to identify and quantify specific DNA or RNA sequences, aiding in the early and precise diagnosis of diseases. The versatility of PCR enables diagnostic centers to offer a wide range of tests, contributing to comprehensive patient care.
North America commanded the largest market share during the extrapolated period. The high frequency of diseases, the presence of important players in the region, the existence of favourable regulations, and a number of government initiatives pertaining to advancements in healthcare infrastructure all contribute to the growth of the regional market. An additional factor fueling the growth is growing patient awareness of the availability of contemporary products for successful diagnosis.
Asia Pacific is expected to witness profitable growth over the projection period, owing to the rising incidence of infectious diseases, the growing recognition of personalized medicine, and the improvements made to the healthcare system. Asian countries are seeing an increase in research endeavours, specifically in the fields of genomics, oncology, and infectious disease investigations. This has led to the widespread use of PCR as a precise and efficient method of amplifying DNA. Moreover, the region's diverse population and genetic variations necessitate robust molecular diagnostics for personalized treatment strategies, further fueling the PCR market.
Some of the key players in the Polymerase Chain Reaction (PCR) Market include Danaher Corporation, Fluidigm Corporation, Agilent Technologies, Inc., Stilla Technologies, Abbott, Cytiva, Microsynth AG, Qiagen, JN Medsys, Bio-Rad Laboratories, Inc., Thermo Fisher Scientific, Inc., F. Hoffmann-La Roche Ltd, Siemens, Johnson & Johnson Private Limited and Bruker.
In August 2022, Abbott and weightwatchers partner to support people living with diabetes in attaining their health goals. Two industry leaders join forces to empower people living with diabetes by providing information and insights to improve weight loss, glucose control and overall health.
In June 2021, Bio-Rad Laboratories, Inc., a global leader of life science research and clinical diagnostic products, announced a partnership with Seegene, Inc., a global leader in multiplex molecular diagnostics, for the clinical development and commercialization of infectious disease molecular diagnostic products.