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市場調查報告書
商品編碼
1403373
全基因組定序市場的全球市場預測(-2030):按產品類型、工作流程、技術、應用、最終用戶和地區進行分析Whole Genome Sequencing Market Forecasts to 2030 - Global Analysis By Product (Consumables, Instruments and Services), Type (Small Whole Genome Sequencing & Large Whole Genome Sequencing), Workflow, Technology, Application, End User and By Geography |
2023年全球全基因組定序市場規模為452.8億美元,預估2030年將達845.1億美元,預測期間內複合年成長率為13.5%。
全基因組定序 (WGS) 是一種用於確定生物體基因組完整 DNA 序列的綜合方法。基因組是DNA的完整集合,包括攜帶生物體發育、功能和維持的遺傳資訊的所有基因和非編碼區。全基因組定序在推動基因組學領域的研究和臨床應用方面發揮著重要作用。
根據美國疾病管制與預防中心的統計,美國大約每 707 名新生兒中就有 1 人患有唐氏症,即約 5,568 名嬰兒患有唐氏症。
遺傳病患病率上升
WGS 是識別與各種疾病相關的遺傳變異的強大工具。隨著遺傳病患疾病率的增加,對準確、全面的診斷方法的需求也隨之增加。全基因組定序可以對個體的整個基因組進行徹底檢查,從而深入了解疾病的遺傳基礎。 WGS 支持更了解潛在遺傳機制的研究工作。此外,人們對早期檢測和介入遺傳疾病管理重要性的認知不斷提高,也促進了對全基因組定序的需求。
在某些疾病狀態下臨床效用的局限性
某些疾病狀態,特別是複雜和多因素的疾病,可能具有尚未明確定義或易於解決的遺傳基礎。在某些情況下,特定基因組觀察與臨床結果之間的關聯尚未明確。缺乏可操作的資訊可能會限制全基因組定序的臨床效用,醫療保健提供者可能很難使用遺傳資料來指導治療決策。它也引發了人們對如何處理此類情況的道德擔憂。這阻礙了 WGS 融入臨床實踐。
腫瘤科招聘增加
全基因組定序可以對患者的基因組成進行全面分析,從而更好地了解癌症的分子促進因素。它有助於識別促進癌細胞生長的特定基因突變或變化。 WGS資料在腫瘤學研究中的使用有助於確定合適的臨床試驗候選者。隨著更多臨床證據的產生以及該技術變得更容易獲得和更具成本效益,WGS 在腫瘤學中的採用可能只會增加,從而推動市場擴張。
資料隱私和安全問題
基因組資料高度敏感,包含有關個體獨特遺傳傾向、疾病傾向和其他潛在個人特徵的資訊。詐欺存取基因組資料的風險引起了人們對濫用敏感資訊的擔憂。如果基因組資料落入壞人之手,它可以用於多種目的,包括身分盜竊、保險歧視和其他惡意活動。如果無法充分解決這些問題,可能會阻礙全基因組定序市場的成長。
COVID-19 大流行對全基因組定序市場產生了中性影響。這次大流行凸顯了遺傳學在理解和預防感染疾病方面的作用。世界各地的研究人員利用全基因組定序來研究 SARS-CoV-2 病毒的基因組成和演化歷史。這凸顯了遺傳學在個體化治療中的重要性。另一方面,市場暫時受到供應鏈中斷、研究目標變化等變數的影響。
精準醫療領域預計將在預測期內成為最大的領域
精準醫療領域估計是一個利潤豐厚的市場。精準醫療涉及根據每個患者的特徵做出醫療和保健決策。全基因組定序在精準醫學中發揮核心作用,提供個體整個基因組的全面分析。這有助於藥物選擇和給藥最佳化。此外,它還提供具有成本效益的治療、患者賦權和個體化護理計劃,這些計劃正在加速該細分市場的成長。
研究中心部門預計在預測期內複合年成長率最高。
由於廣泛研究領域的進步,研究中心領域預計在預測期內將出現最高的複合年成長率。 WGS 在研究中心提供了無數的應用和優勢,有助於對遺傳學、基因組學和各種生物過程的批判性理解。它也為了解疾病機制、確定潛在的治療標靶和開發個體化治療方法提供了重要資訊。
由於研發活動投資的增加,預計亞太地區在預測期內將佔據最大的市場佔有率。亞太地區的生物技術和醫療領域正在經歷顯著成長。各國政府啟動了資助計畫和支持政策,鼓勵採用基因組技術進行研究和臨床應用。該地區人口的多樣化和常見疾病日益流行正在推動市場擴張。
由於政府財政支持的增加,預計北美在預測期內的複合年成長率最高。該地區擁有許多專注於基因組學和個人化醫療的大型生物技術和製藥公司。北美消費者有興趣了解他們的血統、某些健康狀況的傾向以及其他基因組資訊。此外,全基因組定序及其在癌症治療中的應用不斷湧現的技術創新正在加強該地區的市場趨勢。
According to Stratistics MRC, the Global Whole Genome Sequencing Market is accounted for $45.28 billion in 2023 and is expected to reach $84.51 billion by 2030 growing at a CAGR of 13.5% during the forecast period. Whole Genome Sequencing (WGS) is a comprehensive method used to determine the complete DNA sequence of an organism's genome. The genome is the complete set of DNA, including all of the genes and non-coding regions that carry the genetic information for the development, functioning, and maintenance of an organism. Whole genome sequencing plays a critical role in advancing both research and clinical applications in the field of genomics.
According to the Centers for Disease Control and Prevention statistics, around 1 in every 707 newborn children in the U.S. suffer from Down syndrome, which accounts for approximately 5,568 children in the U.S.
WGS is a powerful tool for identifying genetic variations associated with various disorders. As the prevalence of genetic disorders increases, there is a growing need for accurate and comprehensive diagnostic methods. WGS allows for a thorough examination of an individual's entire genome, providing insights into the genetic basis of diseases. It fuels the research efforts to better understand the underlying genetic mechanisms. Further, the rising awareness of the importance of early detection and intervention in managing genetic disorders contributes to the demand for WGS.
In certain medical conditions, especially complex and multifactorial diseases, the genetic basis may not be well-defined or easily actionable. In some cases, the relevance of specific genomic findings to clinical outcomes may not be well-established. This lack of actionable information can limit the clinical utility of WGS, as healthcare providers may struggle to use the genetic data to inform treatment decisions. It also raises ethical concerns about how to handle such conditions. Thereby, it hinders the integration of WGS into clinical practice.
Whole genome sequencing enables a comprehensive analysis of a patient's genetic makeup, allowing for a better understanding of the molecular drivers of cancer. It helps to identify specific genetic mutations and alterations that drive the growth of cancer cells. The use of WGS data in oncology research is instrumental in the identification of suitable candidates for clinical trials. As more clinical evidence is generated, and the technology becomes more accessible and cost-effective, the adoption of WGS in oncology is likely to continue its upward trajectory, driving market expansion.
Genomic data is highly sensitive and contains information about an individual's unique genetic makeup, predispositions to diseases, and potentially other personal traits. The risk of unauthorized access to genomic data raises concerns about the misuse of sensitive information. If genomic data falls into the wrong hands, it could be exploited for various purposes, including identity theft, insurance discrimination, or other malicious activities. Failure to adequately address these concerns can impede the growth of the whole genome sequencing market.
The covid pandemic had a neutral effect on the whole genome sequencing market. The pandemic highlighted the role that genetics plays in comprehending and preventing infectious illnesses. Whole genome sequencing has been used by researchers all around the world to examine the genetic composition and evolutionary history of the SARS-CoV-2 virus. This lightened the significance of genetics in personalized treatment. On the other hand, the market was momentarily impacted by variables including the interruption of supply networks and changes in research objectives.
The precision medicine segment is estimated to have a lucrative. Precision medicine involves tailoring medical treatment and healthcare decisions to the individual characteristics of each patient. Whole genome sequencing plays a central role in precision medicine, providing a comprehensive analysis of an individual's entire genome. It helps to optimize drug selection and dosage. Additionally, it offers cost effective treatments, patient empowerment and personalized care plans which accelerates the segment growth.
The research centers segment is anticipated to witness the highest CAGR growth during the forecast period, due to the advancements in a wide range of research fields. WGS offers a myriad of uses and benefits in research centers, contributing to the significant understanding of genetics, genomics, and various biological processes. It also provides critical information for understanding disease mechanisms, identifying potential therapeutic targets, and developing personalized treatment approaches.
Asia Pacific is projected to hold the largest market share during the forecast period owing to the growing investment in R&D activities. The Asia-Pacific region has experienced substantial growth in the biotechnology and healthcare sectors. Governments have initiated funding programs and supportive policies to encourage the adoption of genomic technologies for research and clinical applications. The region's diverse population along with growing generic disorders is boosting the market's expansion.
North America is projected to have the highest CAGR over the forecast period, owing to the rising government funding. The region hosts numerous leading biotechnology & pharmaceutical companies focused on genomics and personalized medicine. Consumers in North America have shown interest in learning about their ancestry, predisposition to certain health conditions, and other genomic information. Further, the rising innovation in whole genome sequencing and its application in cancer treatments are thereby augmenting the regional market trends.
Some of the key players profiled in the Whole Genome Sequencing Market include Siemens Healthineers, Thermo Fisher Scientific Inc, F. Hoffmann-La Roche Ltd, Danaher Corporation, Agilent Technologies Inc, Illumina Inc, Complete Genomics, QIAGEN N.V., GeneDx, Merck KGaA, Abbott, Eurofins Scientific, Oxford Nanopore Technologies, Bio-Rad Laboratories, Inc and Macrogens Inc.
In October 2023, Oxford Nanopore Technologies and Fabric Genomics collaborated to launch an integrated whole-genome sequencing solution to advance the future of paediatric patient care. The joint solution, which will be commercially available for deployment in CLIA/CAP labs, will support use of nanopore sequencing in neonatal/pediatric intensive care units.
In October 2023, Complete Genomics, a pioneering genomic sequencing company, launched its DNBSEQ-T20x2* product, which reduced the cost of whole genome sequencing to less than $100 per 30X WGS.
In August 2023, GeneDx and PacBio announced research collaboration with the University of Washington to study the capabilities of HiFi long-read whole genome sequencing (WGS) to increase diagnostic rates in pediatric patients with genetic conditions.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.