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市場調查報告書
商品編碼
1403426
遲發性治療藥物到2030年的全球市場預測:依產品類型、疾病類型、給藥途徑、配銷通路和地區進行分析Tardive Dyskinesia Therapeutics Market Forecasts to 2030 - Global Analysis By Product Type, Disease Type, Route Of Administration, Distribution Channel and By Geography |
根據 Stratistics MRC 的數據,2023 年全球遲發性藥物市場規模將達到 25 億美元,預計 2030 年將達到 54 億美元,預測期內複合年成長率為 11.1%。
藥物引起的運動疾病稱為遲發性(TD),會導致舌頭、臉部、軀幹和四肢不受控制地運動。遲發性是長期使用某些精神藥物(如抗精神病藥物)的副作用。儘管有時也會影響其他患者,但這種疾病最常見於長期服用抗精神病藥物的精神分裂症、分裂情感性疾患和躁鬱症患者。
根據 John Wiley &Sons, Inc. 於 2022 年 8 月發表的一篇論文,在歐洲接受抗精神病藥物治療的精神病患者中,遲發性的盛行率為 23.3%。
遲發性盛行率上升
提高認知可能有助於早期發現和治療,減輕症狀的嚴重。研究的進步將導致更專業的藥物和治療方法的開發,為受影響的人提供更個性化的護理。此外,提高意識將鼓勵為進一步研究提供資金籌措,激發創造力,發現治療和預防遲發性的新方法,並最終減少受這種疾病影響的人數,提高人們的生活品質。
複雜的管理
遲發性的治療通常涉及多種策略的組合,包括改變目前的治療方案或添加新的治療方案。這種複雜性可能會使治療變得困難,尤其是在兼顧控制原始藥物所治療的潛在疾病的需要時。用於控制它的治療方法可能會產生輕微到嚴重的副作用,可能需要密切監測和管理。
改善識別和診斷
早期發現可以及時治療,減緩病程並改善患者的治療效果。更多知識使醫療保健專業人員能夠積極監測患者,從而更容易快速改變處方時間表或使用其他治療方法來控制症狀。此外,增加知識有助於患者教育和支持、減少恥辱並促進富有同情心的醫療保健方法。這樣的綜合策略最終將改善人們的生活品質並促進市場擴張。
製藥公司研發投入限制
治療罕見疾病藥物研發的主要挑戰之一是能夠參與臨床試驗的患者數量較少。只有幾百、幾千名罕見疾病患者有資格參加臨床試驗。罕見疾病患者數量非常少。此外,研究費用昂貴且投資回報不明,這可能導致製藥公司不願為其提供資金。
這場大流行擾亂了全球醫療保健服務,影響了常規檢查、專家諮詢以及面對面治療的可用性。結果,許多遲發性患者的治療被推遲或中斷。 COVID-19 影響了正在進行的與遲發性相關的臨床試驗和研究的進展。由於探視限制或入組挑戰,一些臨床試驗可能會被推遲或修改。
預計在預測期內,丁苯那嗪部分將是最大的
預計Deutetrabenazine細分市場在預測期內將是最大的細分市場。氘替代延長了半衰期,提高了療效和安全性,減少了與給藥相關的副作用,並提高了患者的醫囑遵從性。這種化合物有望抑制與遲發性相關的不自主運動,從而提供更一致且更易於管理的治療方法。
遲發性肌張力不全症地區預計在預測期內複合年成長率最高
遲發性肌張力不全症領域預計在預測期內複合年成長率最高。遲發性肌張力不全症是遲發性的一種亞型,具體涉及持續的肌肉收縮,導致重複的扭轉運動和異常姿勢。調整或停用引發遲發性肌張力不全症的藥物可能會改善或消除症狀。然而,這種情況必須由醫療專業人員仔細處理,平衡藥物的益處與精神狀態惡化的風險。
預計北美在預測期內將佔據最大的市場佔有率。多家製藥公司正在投資開發專門用於症狀管理的藥物。這些治療旨在透過減輕與疾病相關的不自主運動來改善受影響個體的生活品質。隨著治療方法選擇的進步以及醫療保健提供者對這些治療方法的接受程度不斷提高,市場正在呈現成長。
由於醫療保健意識的提高、診斷技術的改進和高齡化,預計亞太地區在預測期內將保持最高的複合年成長率。製藥公司正在努力開發針對症狀的新治療方法和藥物,以解決該領域未滿足的醫療需求。國內和全球製藥公司之間的合作以及診斷和治療技術的進步也有助於該地區的市場擴張。
According to Stratistics MRC, the Global Tardive Dyskinesia Therapeutics Market is accounted for $2.5 billion in 2023 and is expected to reach $5.4 billion by 2030 growing at a CAGR of 11.1% during the forecast period. A drug-induced movement condition called tardive dyskinesia (TD) results in uncontrollably moving the tongue, face, torso, and limbs. It is a side effect brought on by extended use of specific psychiatric drug classes, such antipsychotics. Although they sometimes afflict other patients as well, the illness is most frequent among those who have been taken long-term antipsychotic drugs for schizophrenia, schizoaffective disorder, or bipolar disorder.
According to an article published by John Wiley & Sons, Inc., in August 2022, the prevalence of tardive dyskinesia in Europe is 23.3% amongst psychiatric patients receiving treatment with antipsychotics.
Increased consciousness encourages early identification and action, which may lessen the severity of symptoms. Research progresses lead to the creation of more specialized drugs and therapies, providing impacted people with more individualized care. Furthermore, greater awareness encourages financing for additional research, which spurs creativity and reveals fresh approaches to tardive dyskinesia therapy and prevention, eventually enhancing the quality of life for individuals affected by the disorder.
The management of tardive dyskinesia frequently entails a mix of strategies, such as changing current prescriptions or adding new ones. This intricacy can make treatment difficult, particularly when juggling the requirement to manage the underlying condition for which the original medication was prescribed. Therapeutic options for management have a range of side effects, from mild to severe, which may require close monitoring and management.
Early detection enables timely management, which may slow its course and enhance patient outcomes. Increased knowledge encourages healthcare professionals to monitor patients proactively, which makes it easier to control symptoms by promptly changing prescription schedules or using other therapies. Moreover, better knowledge promotes patient education and support, lessens stigma, and encourages a more compassionate approach to healthcare. This all-encompassing strategy eventually improves people's quality of life, which fuels market expansion.
One of the major challenges of rare disease drugs in terms of research and development is the small patient population available for clinical trials. Only a few hundred or few thousand patients with rare diseases are accessible for clinical trials. Rare diseases afflict a tiny population. Furthermore, because research may be expensive and have hazy returns on investment, pharmaceutical corporations could be reluctant to fund it.
The pandemic caused disruptions in healthcare services globally, affecting regular check-ups, access to specialists, and availability of in-person treatments. This led to delays or interruptions in treatment for many individuals with tardive dyskinesia. COVID-19 impacted the progress of ongoing clinical trials and research studies related to tardive dyskinesia. Some trials might have been delayed or modified due to restrictions on in-person visits and enrollment challenges.
The deutetrabenazine segment is expected to be the largest during the forecast period. Its deuterium substitution enhances its efficacy and safety profile by prolonging its half-life, leading to fewer dose-related side effects and improved patient adherence. This compound demonstrates potential in reducing involuntary movements associated with Tardive Dyskinesia while offering a more consistent and manageable treatment approach.
The tardive dystonia segment is expected to have the highest CAGR during the forecast period. Tardive dystonia, a subtype of tardive dyskinesia, specifically involves sustained muscle contractions causing repetitive, twisting movements or abnormal postures. Sometimes, adjusting or discontinuing the medications that trigger tardive dystonia can lead to improvement or resolution of symptoms. However, this must be carefully managed by a healthcare professional to balance the benefits of the medication with the risk of worsening psychiatric conditions.
North America is projected to hold the largest market share during the forecast period. Several pharmaceutical companies have been investing in developing medications specifically targeted to manage symptoms. These treatments aim to alleviate the involuntary movements associated with the condition, thereby improving the quality of life for affected individuals. The market has shown growth in terms of advancements in therapeutic options and the growing acceptance of these treatments among healthcare providers.
Asia Pacific is projected to hold the highest CAGR over the forecast period due to rising healthcare awareness, improving diagnostic techniques, and an aging population. Pharmaceutical companies were working on developing new treatments and medications targeting symptoms, aiming to address the unmet medical needs in this area. Collaborations between local and global pharmaceutical companies, as well as advancements in technology for diagnosis and treatment, were also contributing to the expansion of the market in the region.
Some of the key players in Tardive Dyskinesia Therapeutics market include Mitsubishi Tanabe Pharma Corporation, Luye Pharma Group, Teva Pharmaceutical Industries Ltd., Neurocrine Biosciences, Inc., SOM BIOTECH, Sun Pharmaceutical Industries Ltd, AbbVie Inc , Sanis, SteriMax Inc., Adamas Pharmaceuticals, Inc , Reddys Laboratories Ltd, Mylan N.V., Bausch Health, Johnson & Johnson Services, Lupin Pharmaceuticals Inc, Novartis AG, Baxter, Amgen Inc, Pfizer Inc and Medicure Inc.
In February 2023, Teva Pharmaceuticals announced the print publication of the IMPACT-TD Scale, an easy-to-use, standardized and clinician-rated assessment. The scale, developed by a consensus panel, will assist healthcare providers in determining the impact of tardive dyskinesia (TD) on different aspects of a patient's daily functioning.
In December 2021, Mitsubishi Tanabe Pharma Corporation and Janssen Pharmaceutical K.K. have entered into a co-promotion agreement for MT-5199, a vesicular monoamine transporter type 2 (VMAT2) inhibitor, which is intended for use as tardive dyskinesia therapeutics in Japan.