市場調查報告書
商品編碼
1438063
2030 年促紅血球生成素藥物市場預測:按類型、產品、分銷管道、應用、最終用戶和地區進行的全球分析Erythropoietin Drugs Market Forecasts to 2030 - Global Analysis By Type (Biosimilars and Biologics), Product (Epoetin-alfa, Epoetin-beta, Darbepoetin-alfa and Other Products), Distribution Channel, Application, End User and By Geography |
根據Stratistics MRC預測,2023年全球促紅血球生成素藥物市場規模將達107億美元,預計2030年將達到256億美元,預測期內年複合成長率為13.2%。
促紅血球生成素製劑是一類包含促紅血球生成素(腎臟天然產生的荷爾蒙)重組製劑的藥物。這些藥物目的是刺激和增加紅血球合成,可有效控制與貧血相關的症狀。促紅血球生成素製劑可透過增加紅血球數量來治療虛弱、呼吸困難和頭暈等貧血症狀,改善患者的日常功能。
根據世界衛生組織(WHO)的資料,全球 42%的 5 歲以下兒童和 40%的孕婦患有貧血。
貧血增加
貧血是一種以紅血球數量減少或血紅素數量減少為特徵的疾病,導致血液攜氧能力下降。 EPO 製劑透過促進紅血球的產生,在貧血治療中發揮重要作用。此外,癌症患者通常會使用 EPO 製劑來控制化療引起的貧血並提高生活品質。這些疾病的日益普及導致貧血的整體負擔增加,推動了對 EPO 製劑的需求。
可能的副作用
促紅血球生成素藥物市場面臨一個潛在的限制因素:與藥物使用相關的副作用的發生。主要關注點之一是與服用促紅血球生成素製劑相關的心血管事件風險,例如血栓症和高血壓。此外,另一個潛在的副作用是發生純紅血球再生不良性貧血(PRCA),這是一種罕見但嚴重的疾病,其特徵是紅血球產生突然停止。
提高醫療保健意識
醫療保健意識的提高是促紅血球生成素製劑市場的關鍵促進因素。隨著患者和醫療保健專業人員對包括貧血在內的健康狀況的認知不斷提高,人們越來越認知到促紅血球生成素製劑在治療貧血相關併發症中的重要性。此外,越來越多的患者尋求及時有效的治療,其中促紅血球生成素製劑發揮重要作用,例如慢性腎臟病。這些因素推動市場需求。
新的替代藥物
隨著科學和醫學研究的進展,新的治療選擇,包括非藥物干預和替代藥物療法越來越受到關注,挑戰促紅血球生成素製劑的優越性。此外,市場上生物相似藥的供應和採用的增加可能會導致定價壓力和市場佔有率競爭,影響品牌促紅血球生成素產品的收益。
COVID-19 的影響
由於COVID-19大流行,促紅血球生成素製劑市場受到了重大影響。非緊急醫療程序和治療,包括治療貧血的促紅血球生成素產品,被推遲或延遲,影響了整體市場需求。此外,藥品供應鏈的中斷、旅行限制和勞動力短缺阻礙了促紅血球生成素產品的生產和分銷。
腫瘤學領域預計在預測期內規模最大
預計癌症領域將佔據最大佔有率。癌症患者常因疾病本身或化療的副作用而出現貧血。促紅血球生成素製劑,例如阿法紅血球生成素,透過刺激紅血球的產生來治療癌症患者的貧血。此外,促紅血球生成素治療可改善患者健康,並可透過維持足夠的攜氧紅血球來實現更有效的癌症治療。
生物製藥產業預計在預測期內年複合成長率最高。
預計生技藥品領域將在預測期內出現良好的成長。生技藥品目的是模仿促紅血球生成素刺激骨髓中紅血球生成的天然能力。促紅血球生成素生物製藥通常用於治療與慢性腎臟病、癌症化療和某些其他醫療狀況相關的貧血。此外,生物製藥,包括基於促紅血球生成素的藥物,透過為貧血提供有針對性的有效治療,為患者的治療做出了重大貢獻。
由於強大的醫療基礎設施、技術創新和高普及率,北美在估計期間佔據了最大的市場佔有率。貧血的流行,特別是在接受透析的 CKD 患者和接受癌症治療的患者中,推動北美對促紅血球生成素產品的需求。此外,該地區也處於生物技術和藥物研究的前沿,支持促紅血球生成素配方開發的持續創新。
亞太地區預計將在預測期內實現有益成長,因為它對全球製藥業做出了重大貢獻。中國和印度等國家已成為促紅血球生成素製劑生產和消費的主要參與者。該地區的製藥業經歷高度的研發活動,推動創新並推出新的 EPO 配方。此外,亞太地區不斷發展的醫療基礎設施和不斷增加的醫療費用也促進了促紅血球生成素製劑市場的成長。
According to Stratistics MRC, the Global Erythropoietin Drugs Market is accounted for $10.7 billion in 2023 and is expected to reach $25.6 billion by 2030 growing at a CAGR of 13.2% during the forecast period. Erythropoietin drugs are a class of medications that include recombinant forms of erythropoietin, a hormone produced naturally in the kidneys. These drugs are designed to stimulate and increase the synthesis of red blood cells, making them effective in managing conditions associated with anaemia. Erythropoietin medications treat anaemia symptoms such as weakness, dyspnea, and vertigo by raising red blood cell counts, leading to improved daily functioning for patients.
According to the World Health Organization (WHO), 42% of children under the age of five and 40% of pregnant women worldwide are anemic.
Rising prevalence of anaemia
Anaemia is a condition characterized by a decrease in the number of red blood cells or a decrease in the amount of haemoglobin, leading to reduced oxygen-carrying capacity in the blood. EPO drugs play a crucial role in managing anaemia by stimulating the production of red blood cells. Moreover, EPO drugs are often prescribed to cancer patients to manage chemotherapy-induced anaemia and improve their quality of life. The increasing prevalence of these conditions contributes to the overall burden of anaemia in the population, thereby driving the demand for EPO drugs.
Potential adverse effects
The erythropoietin drug market faces potential restraints linked to the occurrence of adverse effects associated with the therapeutic use of these drugs. One significant concern is the risk of cardiovascular events, including thrombosis and hypertension, associated with the administration of erythropoietin drugs. Furthermore, another potential adverse effect is the development of pure red cell aplasia (PRCA), a rare but serious condition characterized by a sudden halt in the production of red blood cells.
Increased healthcare awareness
Increased healthcare awareness serves as a pivotal driver in the erythropoietin drugs market. As awareness about health conditions, including anemia, continues to rise among patients and healthcare professionals, there is a heightened recognition of the significance of erythropoietin drugs in managing anemia-associated complications. Moreover, patients are increasingly seeking timely and effective treatments for conditions like chronic kidney disease and other disorders where erythropoietin drugs play a vital role. These factors drive market demand.
Emerging alternatives
As scientific and medical research progresses, new therapeutic options, including non-pharmacological interventions and alternative drug therapies, are gaining attention and posing a challenge to the dominance of erythropoietin drugs. Moreover, the increasing availability and adoption of biosimilars in the market can lead to pricing pressures and market share competition, impacting the revenue of branded erythropoietin drugs.
Covid-19 Impact
The erythropoietin drug market experienced notable impacts from the COVID-19 pandemic. Non-urgent medical procedures and treatments, including those involving erythropoietin drugs for anaemia, were deferred or delayed, affecting the overall market demand. Additionally, disruptions in the pharmaceutical supply chain, restrictions on movement, and workforce shortages posed obstacles to the production and distribution of erythropoietin drugs.
The cancer segment is expected to be the largest during the forecast period
The cancer segment is estimated to hold the largest share. Cancer patients frequently experience anaemia due to the effects of the disease itself or as a side effect of chemotherapy. Erythropoietin drugs, such as epoetin-alfa, are employed to address anaemia in cancer patients by stimulating the production of red blood cells. Moreover, erythropoietin therapies improve the patient's well-being, potentially allowing for more effective cancer treatment by maintaining adequate levels of oxygen-carrying red blood cells.
The biologics segment is expected to have the highest CAGR during the forecast period
The biologics segment is anticipated to have lucrative growth during the forecast period. Biologics are designed to mimic the natural function of erythropoietin in stimulating the production of red blood cells in the bone marrow. Erythropoietin biologics are commonly used to address anaemia associated with chronic kidney disease, cancer chemotherapy, and certain other medical conditions. Additionally, biologics, including erythropoietin-based agents, contribute significantly to patient care by offering targeted and effective treatments for anaemia.
North America commanded the largest market share during the extrapolated period owing to robust healthcare infrastructure, technological innovation, and a high prevalence of conditions. The prevalence of anaemia, particularly in CKD patients undergoing dialysis and individuals undergoing cancer treatments, has fuelled the demand for erythropoietin drugs in North America. Moreover, the region is also at the forefront of biotechnological and pharmaceutical research, driving continuous innovation in erythropoietin drug development.
Asia Pacific is expected to witness profitable growth over the projection period, owing to its significant contribution to the global pharmaceutical industry. Countries like China and India have emerged as key players in the production and consumption of erythropoietin drugs. The region's pharmaceutical sector benefits from robust research and development activities, fostering innovation and the introduction of new EPO formulations. Additionally, the Asia-Pacific's evolving healthcare infrastructure and increasing healthcare expenditure contribute to the growth of the erythropoietin drug market.
Key players in the market
Some of the key players in the Erythropoietin Drugs Market include Johnson & Johnson Services, Inc., AstraZeneca, Amgen, Inc., Novartis AG, Teva Pharmaceutical Industries Ltd., Pfizer Inc, LG Chem, F. Hoffmann-La Roche Ltd., Sun Pharmaceutical Industries Ltd., Intas Pharmaceuticals Ltd., Dr. Reddy's Laboratories Ltd, Ranbaxy Laboratories and Roche Diagnostics.
In November 2023, AstraZeneca announced a collaboration and investment agreement with Cellectis, a clinical-stage biotechnology company, to accelerate the development of next generation therapeutics in areas of high unmet need, including oncology, immunology and rare diseases.
In September 2023, Sun Pharmaceutical Industries Limited announced that it had entered into a licence agreement with American biopharmaceutical company Pharmazz Inc to commercialise an innovative drug, Tyvalzi (Sovateltide) in India.
In January 2022, Amgen and Generate Biomedicines announced a research collaboration agreement to discover and create protein therapeutics for five clinical targets across several therapeutic areas and multiple modalities.
In October 2020, Novartis and Molecular Partners AG announced collaboration in the form of an option and license agreement to develop, manufacture and commercialize Molecular Partners' anti-COVID-19 DARPin® program, consisting of two therapeutic candidates, MP0420 and MP0423.