市場調查報告書
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1503309
2030 年 3D 細胞培養市場預測:按產品、應用、最終用戶和地區進行的全球分析3D Cell Culture Market Forecasts to 2030 - Global Analysis By Product, Application, End User and By Geography |
根據 Stratistics MRC 的數據,2024 年全球 3D 細胞培養市場規模為 27.8 億美元,預計預測期內複合年成長率為 20.2%,到 2030 年將達到 83.8 億美元。
生物研究中使用一種稱為 3D 細胞培養的複雜尖端方法,在3D和接近生物組織自然條件的環境中培養細胞。與傳統的 2D 細胞培養(細胞在平坦、堅硬的表面上培養)相比,3D 細胞培養系統允許細胞從各個方向與周圍環境相互作用,從而提供更生理相關的環境。此技術改善了細胞-細胞和細胞-基質相互作用,從而產生更準確的細胞反應和行為。
根據美國癌症研究協會 (AACR) 的說法,3D 細胞培養模型可以更真實地反映癌細胞在人體內的相互作用,從而顯著提高臨床前測試的準確性。
慢性病增加
全球癌症、心血管疾病和神經退化性疾病等慢性疾病的增加加劇了對尖端研究模型的需求。 3D 細胞培養提供了生理學上更準確的模型來研究這些疾病的原因並產生新的治療方法。例如,3D 腫瘤球體可以概括癌症研究中腫瘤微環境的複雜性,包括營養物質、氧氣和治療藥物梯度。此外,它可以為研究抗藥性、轉移和腫瘤生長提供與人體非常相似的環境。
設備和材料成本過高
最初推出和維護 3D 細胞培養系統是令人望而卻步的。生物印表機、微流體裝置和客製化支架等先進技術需要大量資本投資。此外,與傳統的 2D 培養相比,3D 細胞培養的試劑、生長因子和專用培養基的成本通常更高。對於預算有限的小型研究機構和公司來說,如此高成本可能令人望而卻步,並阻礙普及。
藥物開發和癌症研究的發展
3D 細胞培養技術有潛力為癌症研究和藥物開發帶來顯著益處。與傳統的 2D 培養相比,球體和類器官等3D腫瘤模型更忠實地再現了腫瘤微環境。這些模型可以更詳細地研究腫瘤生長、轉移和抗藥性。此外,使用3D細胞培養進行高通量藥物篩檢可以提高新型抗癌藥物的鑑定並充分利用現有的治療方法。
監管和道德問題
圍繞 3D 細胞培養技術的法規環境仍在變化,獲得新模型和應用的核准可能是一個困難且耗時的過程。由於需要監管機構提供大量檢驗資料以確保模型的安全性和有效性,這些模型的採用可能會減慢。圍繞著人類來源的細胞,特別是幹細胞的使用也出現了倫理問題。此外,道德核准和監管合規的需要使得研究過程變得更加複雜和昂貴。
3D 細胞培養市場受到了 COVID-19 大流行的顯著影響,無論是正面還是負面。一方面,對疫苗和有效治療方法的迫切需求加速了研發工作,導致採用複雜的 3D 細胞培養模型來研究病毒和測試潛在的治療方法。這些模型為分析抗病毒藥物和了解 SARS-CoV-2 感染機制提供了更精確和生理相關的框架。然而,疫情導致了資金分配的變化、研究計劃的延遲和供應鏈的中斷,使得開展新的和正在進行的研究舉措變得困難。
癌症研究領域預計在預測期內規模最大
癌症研究領域的促進因素是癌症盛行率不斷上升,以及迫切需要更精確和生理學準確的模型來研究腫瘤生物學和評估可能的治療方法,該領域在 3D 細胞培養行業中佔據最大的市場佔有率。球體和類器官是 3D 細胞培養系統的兩個例子,它們擴大被使用,因為傳統的 2D 細胞培養通常無法重現複雜的腫瘤微環境。此外,由於這些 3D 模型更接近體內條件,因此可以更準確地進行癌細胞行為、腫瘤進展和轉移的研究。
生物技術和製藥公司領域預計在預測期內複合年成長率最高
在3D細胞培養市場中,複合年成長率最高的領域是生技和製藥公司。該行業的強勁成長得益於其對尖端藥物開發和發現的關注,其中 3D 細胞培養技術至關重要。為了重建組織和器官的複雜微環境,生物技術和製藥公司使用 3D 細胞培養模型。這可以更準確地評估藥物毒性、藥物動力學和功效。此外,對再生療法和個人化醫療的需求正在推動業界採用 3D 細胞培養技術。
北美在 3D 細胞培養市場中佔有最大佔有率。這一優勢得益於多種因素,包括知名生物技術和製藥公司的存在、先進的醫療保健系統、大量的研發支出以及促進最尖端科技採用的強大法規環境。此外,支持生物醫學研究的政府計劃以及學術界和工業界之間的合作也正在加強該領域的市場。
在3D細胞培養市場中,亞太地區的複合年成長率最高。生技和製藥產業不斷擴張,醫療保健基礎設施投資不斷增加,研發活動不斷增加,並且越來越關注個人化醫療和再生療法。這些是推動這一成長的一些因素。此外,鼓勵性的政府計劃、產學界合作以及蓬勃發展的生物製藥市場正在幫助加速 3D 細胞培養技術在亞太地區的採用。
According to Stratistics MRC, the Global 3D Cell Culture Market is accounted for $2.78 billion in 2024 and is expected to reach $8.38 billion by 2030 growing at a CAGR of 20.2% during the forecast period. A sophisticated and cutting-edge method called 3D cell culture is used in biological research to grow cells in an environment that closely resembles three dimensions and the natural conditions of living organisms' tissues. 3D cell culture systems offer a more physiologically relevant context, allowing cells to interact with their surroundings in all directions, in contrast to traditional 2D cell cultures, where cells are grown on flat, rigid surfaces. More accurate cellular responses and behaviours result from the improved cell-cell and cell-matrix interactions brought about by this technique.
According to the American Association for Cancer Research (AACR), 3D cell culture models significantly enhance the accuracy of preclinical testing by providing a more realistic representation of how cancer cells interact within the human body.
Growing rates of chronic illnesses
The need for cutting-edge research models is being driven by the global rise in chronic diseases like cancer, cardiovascular disease, and neurodegenerative disorders. More physiologically accurate models for researching the causes of these illnesses and creating novel treatment approaches are offered by 3D cell cultures. For instance, 3D tumor spheroids can replicate the intricacy of tumor microenvironments, including nutrient, oxygen, and therapeutic agent gradients, in cancer research. Additionally, this provides an environment that is very similar to the human body for researchers to study drug resistance, metastasis, and tumor growth.
Exorbitant equipment and material costs
It can be unaffordable to set up and maintain 3D cell culture systems on an initial basis. Significant capital investment is needed for advanced technologies like bioprinters, microfluidic devices, and customized scaffolds. Furthermore, compared to conventional 2D cultures, the cost of reagents, growth factors, and specialized culture media for 3D cell cultures is frequently higher. Widespread adoption may be hampered by this high cost, which may be prohibitive for smaller research organizations and businesses with tighter budgets.
Development in drug development and cancer research
3D cell culture technologies have enormous potential benefits for cancer research and drug development. Compared to conventional 2D cultures, 3D tumor models, such as spheroids and organoids, more closely resemble the tumor microenvironment. More precise research on tumor growth, metastasis, and drug resistance is made possible by these models. Moreover, high-throughput drug screening using 3D cell cultures can improve the identification of novel anticancer medications and maximize currently available treatments.
Regulatory and ethical issues
The regulatory environment surrounding 3D cell culture technologies is still changing, and getting new models and applications approved can be a difficult and drawn-out procedure. The adoption of these models may be slowed down by the need for substantial validation data from regulatory bodies to guarantee the security and effectiveness of the models. Challenges also arise from ethical issues surrounding the use of human-derived cells, particularly stem cells. Additionally, the process of conducting research can become more complex and expensive when ethical approvals and regulatory compliance are required.
The market for 3D cell culture has been significantly impacted by the COVID-19 pandemic, both positively and negatively. On the one hand, research and development efforts were accelerated by the pressing need for vaccines and effective treatments, which led to the adoption of sophisticated 3D cell culture models for studying the virus and testing possible therapies. These models offered more precise and physiologically relevant frameworks for analyzing antiviral medications and comprehending the mechanisms of SARS-CoV-2 infection. However, the pandemic caused funding reallocations, delayed research projects, and upset supply chains, making it difficult to pursue both new and ongoing research initiatives.
The Cancer Research segment is expected to be the largest during the forecast period
Due to the rising incidence of cancer and the urgent need for more precise and physiologically accurate models to investigate tumor biology and assess possible therapies, the cancer research segment holds the largest market share in the 3D cell culture industry. Spheroids and organoids are two examples of 3D cell culture systems that are increasingly being used because traditional 2D cell cultures frequently fall short of replicating the intricate tumor microenvironment. Moreover, studies of cancer cell behavior, tumor progression, and metastasis can be conducted more precisely to these 3D models since they more closely resemble in vivo conditions.
The Biotechnology and Pharmaceutical Companies segment is expected to have the highest CAGR during the forecast period
In the 3D cell culture market, the segment with the highest CAGR is biotechnology and pharmaceutical companies. This industry's strong growth can be attributed to its intense concentration on cutting-edge drug development and discovery, where 3D cell culture technologies are essential. To replicate the complex microenvironments of tissues and organs, biotech and pharmaceutical companies use 3D cell culture models. This allows for a more precise evaluation of drug toxicity, pharmacokinetics, and efficacy. Furthermore, the need for regenerative therapies and personalized medicine is driving the industry's adoption of 3D cell culture techniques.
In the market for 3D cell culture, North America has the largest share. Numerous elements contribute to this dominance, such as the existence of well-known biotech and pharmaceutical firms, a sophisticated healthcare system, large expenditures for R&D, and a strong regulatory environment that promotes the uptake of cutting-edge technologies. Additionally, government programs that support biomedical research and partnerships between academia and business strengthen the market in this area.
In the 3D cell culture market, the Asia-Pacific region exhibits the highest CAGR. The biotechnology and pharmaceutical industries are expanding, healthcare infrastructure investments are rising, research and development activities are increasing, and the focus on personalized medicine and regenerative therapies is becoming more and more important. These are some of the factors driving this growth. Furthermore, encouraging government programs, industry-academia partnerships, and a quickly growing biopharmaceutical market all play a part in the Asia Pacific region's accelerated adoption of 3D cell culture technologies.
Key players in the market
Some of the key players in 3D Cell Culture market include Lena Biosciences, Hurel Corporation, Becton, Dickinson And Company, Lonza AG, Advanced Biomatrix, Inc., InSphero AG, Corning Incorporated, Merck KGaA, Thermo Fisher Scientific, Inc., Reprocell Inc., Avantor, Inc., Synthecon Incorporated, Nortis Inc., Tecan Trading AG, Promocell GmbH, VWR International LLC and Sartorius AG.
In May 2024, Merck KGaA, Darmstadt, Germany has signed a definitive agreement to acquire life science company Mirus Bio for $600 million (around €550 million). Based in Madison, Wisconsin, Mirus Bio is a specialist in the development and commercialization of transfection reagents. Transfection reagents, such as Mirus Bio's TransIT-VirusGEN, are used to help introduce genetic material into cells.
In January 2024, BD (Becton, Dickinson and Company), a leading global medical technology company, announced a collaboration agreement with Hamilton, a leading global manufacturer of laboratory automation technology, to develop automated applications together with robotics-compatible reagent kits to enable greater standardization and reduced human error when conducting large-scale single-cell multiomics experiments.
In June 2023, Corning Incorporated and SGD Pharma announced a joint venture that includes the opening of a new glass tubing facility to expand pharmaceutical manufacturing in India and allows SGD Pharma to adopt Corning's Velocity Vial technology platform.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.