市場調查報告書
商品編碼
1503432
2030 年冷凍電鏡市場預測:按產品、電壓、技術、應用、最終用戶和地區進行的全球分析Cryo-electron Microscope Market Forecasts to 2030 - Global Analysis By Product (Instruments, Software and Services), Voltage (120 KV, 200 KV and 300 KV), Technology, Application, End User and By Geography |
根據 Stratistics MRC 的數據,2024 年全球冷凍電子顯微鏡市場規模為 13.5 億美元,預計在預測期內複合年成長率為 10.7%,到 2030 年將達到 24.8 億美元。
冷凍電子顯微鏡 (Cryo-EM) 是結構生物學中使用的強大工具,可以近原子解析度可視化蛋白質、病毒和其他生物大分子。該技術允許樣品在極低的溫度下快速冷凍,保留其自然結構,無需染色或固定。冷凍電子顯微鏡使用電子束對樣品進行成像,並使用先進的計算技術將其重建為詳細的 3D 模型。此方法在研究難以結晶的複雜分子結構時特別有用,並提供對其功能和機制的重要見解。
對結構生物學的需求不斷成長
對結構生物學不斷成長的需求極大地推動了冷凍電子顯微鏡(Cryo-EM)市場的發展。結構生物學需要生物分子結構的詳細視覺化,以便了解它們的功能和相互作用。冷凍電子顯微鏡可以以近原子解析度觀察這些結構,促進藥物發現、疾病研究和生物技術的突破。冷凍電子顯微鏡解析複雜生物分子的精確度和效率是無與倫比的,使其成為現代結構生物學的重要工具。
維護和營運成本
冷凍電子顯微鏡 (Cryo-EM) 市場受到高昂的維護和營運成本的嚴重限制。這些成本包括定期校準的需要、液態氮等昂貴的消耗品以及需要熟練技術人員的專業維護服務。此外,顯微鏡需要受控的環境,這增加了設備和公用事業成本。設備的複雜性需要持續的操作員培訓,進一步增加了營運成本。這種財務負擔可能會阻止小型機構和研究中心採用冷凍電子顯微鏡技術。
拓展新的應用領域
擴展到新的應用領域是冷凍電子顯微鏡 (cryo-EM) 市場的重大機會。冷凍電子顯微鏡擴大應用於結構生物學、材料科學和奈米技術等領域。冷凍電子顯微鏡可以提供接近原子解析度的生物分子和複雜材料的高解析度3D影像,在藥物發現、病毒學研究以及新型奈米材料的研發中具有不可估量的價值。冷凍電子顯微鏡在解決跨學科的複雜科學問題方面的多功能性凸顯了其不斷擴大的應用潛力。
技術複雜性
冷凍電子顯微鏡 (Cryo-EM) 市場中技術複雜性的威脅源自於這些設備的複雜設計和複雜操作。冷凍電子顯微鏡系統需要先進的知識來設定、維護和操作,限制了其只能由高度專業的人員使用。此外,低溫、光電和成像技術的整合需要多個科學學科的高水平專業知識。高成本和定期校準的需要使資源匱乏的實驗室的可及性和挑戰傳播更加複雜。
COVID-19 大流行加速了冷凍電子顯微鏡 (Cryo-EM) 在研究和診斷應用中的需求和採用,對冷凍電子顯微鏡 (Cryo-EM) 市場產生了重大影響。了解 SARS-CoV-2 病毒結構和開發疫苗的迫切需求導致對冷凍電子顯微鏡等先進成像技術的投資增加。許多研究機構和製藥公司擴大了其冷凍電子顯微鏡設施,以實現對病毒和蛋白質的快速結構分析。因此,儘管供應鏈和製造因停工而中斷,但市場仍在成長。
核磁共振 (NMR) 顯微鏡產業預計在預測期內規模最大
核磁共振 (NMR) 顯微鏡在冷凍電子顯微鏡市場的成長歸因於其提供生物分子天然狀態高解析度結構資訊的獨特能力。核磁共振透過提供對原子層級上的動態過程和分子間相互作用的洞察來補充冷凍電子顯微鏡。這種協同效應使研究人員能夠全面了解複雜的生物系統,從而增加了對整合解決方案的需求。此外,核磁共振技術的進步,例如磁場強度的增加和靈敏度的提高,正在提高與冷凍電鏡工作流程的兼容性,進一步促進其採用。
奈米技術產業預計在預測期內複合年成長率最高
奈米技術在冷凍電子顯微鏡 (Cryo-EM) 市場中的擴展是由其無與倫比的以卓越解析度可視化奈米級結構的能力推動的。隨著研究人員深入研究奈米科學領域,對冷凍電子顯微鏡技術的需求正在迅速增加。其在低溫下研究生物樣本的能力提供了對分子結構的寶貴見解,並且在藥物發現和材料科學中很有用。此外,奈米材料合成和表徵的進步需要高解析度成像工具,例如冷凍電子顯微鏡。奈米技術和冷凍電子顯微鏡之間的協同效應正在推動市場成長並促進各個科學領域的創新。
由於多種因素,北美地區的冷凍電鏡市場正在經歷顯著成長。該地區是大型製藥企業和生物技術公司的所在地,推動了藥物發現和開發對先進成像技術的需求。此外,北美學術研究機構正積極將冷凍電鏡應用於結構生物學研究,進一步推動市場成長。該地區強大的基礎設施、先進的技術和有利的法規環境也有助於冷凍電鏡市場的擴張。此外,產業參與者和研究機構之間的合作正在推動創新並加速市場滲透。
由於多種因素,亞太地區冷凍電鏡市場正在經歷強勁成長。各科學領域的研發活動投資不斷增加,推動了對冷凍電子顯微鏡等先進成像技術的需求。製藥和生物技術行業擴大採用冷凍電子顯微鏡技術進行藥物發現和結構生物學研究,這進一步推動了市場的成長。此外,主要市場參與者在該地區擴大業務的存在以及政府促進科學研究的舉措正在推動市場擴張。
According to Stratistics MRC, the Global Cryo-electron Microscope Market is accounted for $1.35 billion in 2024 and is expected to reach $2.48 billion by 2030 growing at a CAGR of 10.7% during the forecast period. A cryo-electron microscope (Cryo-EM) is a powerful tool used in structural biology to visualize proteins, viruses, and other biological macromolecules at near-atomic resolution. This technique involves rapidly freezing samples at cryogenic temperatures to preserve their natural structure without the need for staining or fixing. Cryo-EM uses electron beams to image the samples, which are then reconstructed into detailed 3D models through advanced computational methods. This method is particularly valuable for studying complex molecular structures that are difficult to crystallize, providing critical insights into their function and mechanisms.
Growing demand for structural biology
The growing demand for structural biology is significantly driving the cryo-electron microscope (cryo-EM) market. Structural biology requires detailed visualization of biomolecular structures to understand their functions and interactions. Cryo-EM allows scientists to observe these structures at near-atomic resolution, facilitating breakthroughs in drug discovery, disease research, and biotechnology. The precision and efficiency of cryo-EM in resolving complex biological molecules are unmatched, making it an indispensable tool in modern structural biology.
Maintenance and operational costs
The cryo-electron microscope (Cryo-EM) market is significantly restrained by high maintenance and operational costs. These costs include the need for regular calibration, expensive consumables like liquid nitrogen, and specialized maintenance services that require skilled technicians. Additionally, the microscopes demand a controlled environment, adding to the costs of facilities and utilities. The complexity of the equipment necessitates ongoing training for operators, further increasing operational expenses. These financial burdens can deter smaller institutions and research centers from adopting cryo-EM technology.
Expansion into new application areas
The expansion into new application areas presents a significant opportunity for the cryo-electron microscope (cryo-EM) market. Cryo-EM is increasingly being utilized in diverse fields such as structural biology, materials science, and nanotechnology. Its ability to provide high-resolution, three-dimensional images of biomolecules and complex materials at near-atomic resolutions makes it invaluable for drug discovery, virology research, and the development of novel nanomaterials. The versatility of cryo-EM in addressing complex scientific questions across various domains underscores its expanding application potential.
Technical complexity
The technical complexity threat in the cryo-electron microscope (cryo-EM) market arises from the intricate design and sophisticated operation of these instruments. Cryo-EM systems require advanced knowledge for setup, maintenance, and operation, limiting their use to highly specialized personnel. Additionally, the integration of cryogenics, electron optics, and imaging technology demands significant expertise in multiple scientific domains. The high cost and need for regular calibration further complicate accessibility, posing challenges for widespread adoption in less-resourced laboratories.
The COVID-19 pandemic significantly impacted the cryo-electron microscope (Cryo-EM) market by accelerating its demand and adoption in research and diagnostic applications. The urgent need to understand the SARS-CoV-2 virus structure and develop vaccines prompted increased investment in advanced imaging technologies like Cryo-EM. Many research institutions and pharmaceutical companies expanded their cryo-EM facilities to facilitate rapid virus and protein structure analysis. Consequently, the market experienced growth despite disruptions in supply chains and manufacturing due to lockdowns.
The nuclear magnetic resonance (NMR) microscopy segment is expected to be the largest during the forecast period
The growth of nuclear magnetic resonance (NMR) microscopy within the cryo-electron microscope market stems from its unique ability to provide high-resolution structural information about biological molecules in their native states. NMR complements cryo-EM by offering insights into dynamic processes and molecular interactions at the atomic level. This synergy enables researchers to gain a comprehensive understanding of complex biological systems, driving demand for integrated solutions. Additionally, advancements in NMR technology, such as higher magnetic field strengths and improved sensitivity, enhance its compatibility with cryo-EM workflows, further fueling its adoption.
The Nanotechnology segment is expected to have the highest CAGR during the forecast period
Nanotechnology's expansion in the cryo-electron microscope (Cryo-EM) market is fueled by its unparalleled ability to visualize nanoscale structures with exceptional resolution. As researchers delve deeper into the realm of nanoscience, the demand for cryo-EM technology has surged. Its capability to study biological samples at cryogenic temperatures provides invaluable insights into molecular structures, aiding drug discovery and material science. Moreover, advancements in nanomaterial synthesis and characterization necessitate high-resolution imaging tools like Cryo-EM. This synergy between nanotechnology and cryo-EM is propelling the market's growth and fostering innovation in various scientific disciplines.
The North American region has experienced significant growth in the cryo-electron microscope market due to several factors. There's a strong presence of leading pharmaceutical and biotechnology companies in the region, driving demand for advanced imaging technologies for drug discovery and development. Additionally, academic and research institutions in North America have been actively adopting cryo-EM for structural biology studies, further boosting market growth. The region's robust infrastructure, technological advancements, and favorable regulatory environment also contribute to the expansion of the cryo-EM market. Moreover, collaborations between industry players and research organizations foster innovation and accelerate market penetration.
The Asia-Pacific region has witnessed significant growth in the Cryo-electron Microscope market due to several factors. Increased investment in research and development activities across various scientific disciplines has propelled the demand for advanced imaging technologies like cryo-electron microscopy. Rising adoption of cryo-EM techniques in pharmaceutical and biotechnology industries for drug discovery and structural biology studies has further stimulated market growth. Additionally, the presence of key market players expanding their operations in the region, coupled with government initiatives promoting scientific research, has fueled market expansion.
Key players in the market
Some of the key players in Cryo-electron Microscope market include AstraZeneca PLC, Carl Zeiss AG, Charles River Laboratories International, Inc., Delmic B.V., Electron Microscopy Sciences, Gatan, Inc., Hitachi High-Tech Corporation, Intertek Group PLC, Jena Bioscience GmbH, Jeol Ltd., Judges Scientific PLC, Leica Microsystems by Danaher Corporation, NanoImaging Services, Inc., Spectris PLC, SPT Labtech Ltd. and Thermo Fisher Scientific Inc.
In June 2024, US lab equipment and services business Thermo Fisher Scientific has opened a new clinical and commercial ultra-cold facility in Bleiswijk, Netherlands. The new site specialises in ambient to cryogenic storage, clinical and commercial packaging, labelling and distribution, and clinical qualified person release services.
In April 2024, Total Quality Assurance (TQA) provider Intertek has entered a strategic partnership with software company Trace For Good to launch a software as a service (SaaS) platform to improve traceability and sustainability in textile and apparel supply chains. The platform's feature is said to include supply chain mapping and traceability at the product level, verification of claims and documents, supplier risk assessments, and support in eco-design and Life Cycle Assessment.
Note: Tables for North America, Europe, APAC, South America, and Middle East & Africa Regions are also represented in the same manner as above.