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市場調查報告書
商品編碼
1662731
2030 年 3D 生物列印人體組織市場預測:按技術、應用和地區進行的全球分析3D Bioprinted Human Tissue Market Forecasts to 2030 - Global Analysis By Technology, Application and By Geography |
根據 Stratistics MRC 的數據,全球 3D 生物列印人體組織市場預計在 2024 年將達到 25.9 億美元,到 2030 年將達到 46.7 億美元,預測期內的複合年成長率為 10.3%。
3D 生物列印人體組織是再生醫學和生物醫學研究領域的突破性進展。該技術使用生物墨水(活細胞、生物材料和生長因子的混合物)逐層創建組織結構。這些工程組織在結構、功能和生物特性上與天然人體組織非常相似,因此對於測試藥物、模擬疾病和了解細胞間相互作用非常有用。此外,目前正在研究將這項創新擴展到臨床應用,例如生產針對特定患者的移植物和用於移植的整個器官,以解決捐贈組織的嚴重短缺問題。
根據《機械工程前沿》雜誌發表的一篇評論,“3D生物列印是積層製造的一種擴展應用,它採用自上而下的方法逐層構建複雜組織,目前正在探索其在組織工程和再生醫學中的應用。”
個人化治療興趣日益濃厚
隨著醫療專業人士尋求客製化治療方案來滿足每位患者的需求,個人化醫療領域正在不斷成長。透過 3D 生物列印組織實現的患者特定組織模型的開發可以實現更準確的藥物測試和疾病建模。這些模型可以透過模擬不同患者對特定治療的反應來提高治療效果並減少副作用。此外,臨床和研究環境中對 3D 生物列印組織的需求受到列印與患者基因匹配的組織的能力的推動,為精準醫療創造了新的可能性。
昂貴的生物列印材料和設備
阻礙 3D 生物列印技術市場發展的主要障礙之一仍然是其成本。列印人體組織所需的專用生物印表機價值可達數十萬美元。此外,列印過程中使用的生物墨水價格昂貴,並且必須與活細胞相容並適合組織生長。這些成本使得沒有資金投資該技術的中小型企業和學術機構無法使用3D生物列印。此外,高昂的前期成本限制了生物列印組織的廣泛應用,尤其是在開發中國家,阻礙了其可擴展性。
個性化醫療的發展
3D生物列印將在快速發展的個人化醫療領域中發揮關鍵作用。透過創建適合每個患者基因組成的組織,醫生可以提高器官移植和其他治療的成功率。透過使用生物列印組織來模擬患者的疾病或遺傳狀況,醫生可以在將藥物給予患者之前在這種客製化組織上測試藥物。這提高了治療的準確性,減少了實驗室測試所花費的時間,並有助於防止副作用。此外,對於目前難以治療的疾病,例如罕見疾病或遺傳疾病,可以透過個人化組織列印開發更有效的治療方法。
監管障礙和待核准
漫長而複雜的監管過程是3D生物列印產業面臨的最大風險之一,尤其是在醫療領域。使用活細胞 3D 生物列印組織和器官引發了許多倫理和監管問題。在生物列印組織核准用於人類患者之前,必須通過嚴格的測試以確保安全性、有效性和符合道德準則。許多國家對此的監管路徑仍不明確,這給開發生物列印技術的公司帶來了不確定性。此外,冗長的醫療用途監管核准流程可能會延遲我們進入市場並限制我們快速擴展業務的能力。
3D 生物列印人體組織市場受到了 COVID-19 疫情的多方面影響。一方面,疫情阻礙了研發活動,減緩了生物列印技術的進展。由於製造設施和實驗室暫時關閉,許多公司的臨床測試和製造流程都出現延遲。然而,這場大流行也凸顯了器官移植、組織工程和傳統藥物測試替代方案的需求,並引發了人們對 3D 生物列印人體組織用於疾病建模、藥物發現和疫苗開發的興趣。
噴墨生物列印市場預計將在預測期內佔據最大佔有率
預計噴墨生物列印領域將在預測期內佔據最大的市場佔有率,因為它在創建高解析度組織結構方面具有出色的精度和準確度。透過使用基於液滴的沉積來放置細胞和生物材料,該技術可以創建複雜的組織結構。由於其經濟實惠、可擴展和適應性,噴墨生物列印在組織工程、個人化醫療和藥物測試等應用領域備受青睞。此外,噴墨生物列印在 3D 生物列印行業中佔據主導地位,這是由於其在使用生物墨水方面的多功能性以及在醫學研究應用中的良好記錄。
預計藥物測試和開發部門將在預測期內實現最高的複合年成長率。
預計藥物測試和開發部門在預測期內將呈現最高的成長率。這個市場是由對先進藥物測試平台日益成長的需求所驅動,這些平台比傳統模型更接近人體組織的反應。利用 3D 生物列印組織,製藥公司可以開發出更精確、更有效的藥物,提供比動物試驗更可靠、更符合道德的替代方案。此外,這些組織模式還能實現個人化醫療策略,降低開發成本並加速新藥上市。
預計預測期內北美地區將佔據最大的市場佔有率。這是由於對尖端生物技術研究的大量投入、主要市場參與企業的強大影響力以及 3D 生物列印技術在組織工程和藥物測試等各個行業的日益廣泛的應用所推動。此外,成熟的醫療保健基礎設施、鼓勵醫療創新的政府計劃以及頂尖學術和研究機構的存在進一步推動了該地區市場的成長。美國作為生物列印創新的中心尤其引人注目,促進了3D生物列印組織應用的快速商業化。
預計亞太地區在預測期內將呈現最高的複合年成長率。該地區的生物技術正在快速進步,並且正在不斷推出提高醫學研究和醫療保健能力的舉措。這一成長主要得益於中國、日本和印度等國家製藥和生物技術產業的擴張以及醫療保健基礎設施投資的增加。此外,個人化醫療和更好的藥物檢測技術日益成長的需求也推動了3D生物列印技術的採用,有助於該地區市場的強勁擴張。
According to Stratistics MRC, the Global 3D Bioprinted Human Tissue Market is accounted for $2.59 billion in 2024 and is expected to reach $4.67 billion by 2030 growing at a CAGR of 10.3% during the forecast period. 3D bioprinted human tissue is a revolutionary development in regenerative medicine and biomedical research. This technique uses bioinks-mixtures of living cells, biomaterials, and growth factors-to create tissue constructs layer by layer. These engineered tissues are very useful for testing drugs, simulating diseases, and understanding how cells interact with each other because they are very similar to natural human tissues in terms of structure, function, and biology. Additionally, in order to address the severe lack of donor tissues, research is being conducted to scale this innovation for clinical applications, such as producing patient-specific grafts or even entire organs for transplantation.
According to a review in Frontiers in Mechanical Engineering, "3D bioprinting, which is an extended application of additive manufacturing, is now being explored for tissue engineering and regenerative medicine as it involves the top-down approach of building the complex tissue in a layer-by-layer fashion".
Growing interest in customized treatment
The field of personalized medicine is expanding as medical practitioners seek to customize care to each patient's unique needs. Drug testing and disease modeling can be done more accurately owing to the development of patient-specific tissue models made possible by 3D bioprinted tissues. These models can be used to improve therapeutic efficacy and reduce side effects by simulating how various patients will react to particular treatments. Moreover, the demand for 3D bioprinted tissues in clinical and research settings is being driven by the capacity to print tissues that are genetically matched to patient profiles, which creates new possibilities for precision medicine.
Expensive bioprinting supplies and equipment
One major barrier to the market for 3D bioprinting technology is still its cost. The cost of the specialized bioprinters needed to print human tissues can reach hundreds of thousands of dollars. Furthermore, the bioinks used in the printing process are expensive and need to be compatible with living cells and made for tissue growth. Smaller businesses or academic institutions that might not have the funds to invest in this technology find 3D bioprinting less accessible due to these costs. Furthermore, the high initial costs restrict the widespread use of bioprinted tissue, particularly in developing nations, and impede its scalability.
Development in tailored healthcare
3D bioprinting is positioned to be a key component of the quickly expanding field of personalized medicine. Doctors may be able to increase the success rates of organ transplants and medical treatments by producing tissues that are specifically suited to each patient's genetic composition. Physicians could test medications on these customized tissues before giving them to patients by using bioprinted tissues to simulate a patient's illness or genetic condition. This would improve the accuracy of medical treatments, decrease the amount of time spent in clinical trials, and help prevent adverse reactions. Additionally, more effective treatments for diseases that is currently hard to treat, like rare diseases and genetic disorders, may be developed as a result of personalized tissue printing.
Regulatory obstacles and approval hold-ups
The lengthy and intricate regulatory process is one of the biggest risks facing the 3D bioprinting industry, especially in the medical sector. Using living cells to create 3D bioprinted tissues and organs raises a number of ethical and regulatory issues. Bioprinted tissues must pass stringent testing to guarantee they adhere to safety, effectiveness, and ethical guidelines before being approved for use in human patients. These regulatory pathways are still unclear in many nations, which cause uncertainty for businesses creating bioprinting technologies. Moreover, slow regulatory approval processes for medical applications can postpone market entry and limit the possibility of quick expansion.
The market for 3D bioprinted human tissue was affected by the COVID-19 pandemic in a variety of ways. On the one hand, the pandemic slowed down the advancement of bioprinting technologies by interfering with research and development activities because of lockdowns, travel restrictions, and resource reallocation to fight the virus. Due to the temporary closure of manufacturing facilities and laboratories, many businesses experienced delays in their clinical trials and production processes. However, the pandemic highlighted the need for alternatives to organ transplantation, tissue engineering, and conventional drug testing, which sparked interest in 3D bioprinted human tissues for disease modeling, drug discovery, and vaccine development.
The Inkjet Bioprinting segment is expected to be the largest during the forecast period
The Inkjet Bioprinting segment is expected to account for the largest market share during the forecast period because of its exceptional precision and accuracy in creating high-resolution tissue structures. By placing cells and biomaterials using droplet-based deposition, this technology makes it possible to create intricate tissue structures. Because of its affordability, scalability, and adaptability, inkjet bioprinting is highly preferred for uses such as tissue engineering, personalized medicine, and drug testing. Moreover, its dominance in the 3D bioprinting industry is a result of its versatility in working with bioinks and its proven track record in medical and research applications.
The Drug Testing and Development segment is expected to have the highest CAGR during the forecast period
Over the forecast period, the Drug Testing and Development segment is predicted to witness the highest growth rate. The growing need for sophisticated drug testing platforms that more closely resemble human tissue responses than conventional models is driving this market. Pharmaceutical companies can create medications with greater accuracy and effectiveness by using 3D bioprinted tissues, which provide a more dependable and moral substitute for animal testing. Additionally, these tissue models also enable personalized medicine strategies, which lower development costs and expedite the release of new medications.
During the forecast period, the North America region is expected to hold the largest market share, propelled by substantial expenditures in cutting-edge biotechnology research, a robust presence of important industry participants, and the expanding use of 3D bioprinting technologies across a range of industries, including tissue engineering and drug testing. Furthermore, the region's market growth is further fuelled by established healthcare infrastructures, government programs that encourage medical innovation, and the presence of top academic and research institutions. As a center for bioprinting innovations, the United States stands out in particular, promoting the quick commercialization of 3D bioprinted tissue applications.
Over the forecast period, the Asia Pacific region is anticipated to exhibit the highest CAGR. Rapid biotechnology advancements and a growing number of initiatives to improve medical research and healthcare capabilities are occurring in the region. Growing pharmaceutical and biotechnology industries in nations like China, Japan, and India, as well as rising investments in healthcare infrastructure, are major forces behind this growth. Moreover, the adoption of 3D bioprinting technologies is also being fuelled by the growing need for personalized medicine and better drug testing techniques, which is helping to drive the region's robust market expansion.
Key players in the market
Some of the key players in 3D Bioprinted Human Tissue market include 3D Systems, Inc., General Electric, Organovo Holdings, Inc., Vivax Bio, LLC, The Pexion Group, Materialise NV, EnvisionTEC, Inc., Stratasys Ltd., Oceanz 3D printing Inc, Prellis Biologics Inc, SOLS Systems Inc and Inventia Life Science PTY Ltd.
In June 2024, 3D Systems announced the signing of a multi-year purchase agreement, with a value estimated to approach a quarter-billion dollars through 2028, in support of the indirect manufacturing process for clear aligners. The contract builds upon the exceptional legacy the Company has established as a key supplier of 3D printing technology to the clear aligner industry.
In June 2024, Stratasys Ltd. and Aviation manufacturing pioneer AM Craft announced that they are partnering to align the two companies' efforts to grow the demand for flight-certified 3D printed parts in the aviation industry. The companies signed a definitive commercial collaboration agreement, along with Stratasys' strategic investment in AM Craft.
In January 2022, Prellis Biologics, Inc. (Prellis) announced that it has entered into multi-target drug discovery collaboration and licensing agreement with Bristol Myers Squibb utilizing Prellis Biologics' first-in-class externalized human immune system (EXIS(TM)) based on human lymph node organoids (LNO(TM)).