市場調查報告書
商品編碼
1463684
南美洲和中美洲新生兒篩檢市場預測至 2030 年 - 區域分析 - 按產品類型(試劑和檢測試劑盒及儀器)、技術、測試類型和最終用戶(醫院和診所以及診斷實驗室)South & Central America Newborn Screening Market Forecast to 2030 - Regional Analysis - by Product Type (Reagents and Assay Kits, and Instruments), Technology, Test Type, and End User (Hospitals and Clinics, and Diagnostic Laboratories) |
2022年,南美洲和中美洲新生兒篩檢市場價值為5,808萬美元,預計到2030年將達到10,064萬美元;預計 2022 年至 2030 年CAGR為 7.1%。
新生兒基因篩檢推動南美洲和中美洲新生兒篩檢市場
隨著人們對疾病遺傳原因的認知不斷加深以及醫療保健技術的進步,對新生兒進行全面基因篩檢的需求正在增加。因此,新生兒篩檢市場的公司正在開發創新、經濟高效的篩檢解決方案。 Yescarta 和 Zynteglo 是針對大 B 細胞淋巴瘤和 BETA 地中海貧血的授權基因治療的兩個例子。此外,技術的出現賦予了識別出生時疾病遺傳傾向的能力,為個人化醫療保健鋪平了道路,與精準醫療的更廣泛趨勢保持一致。
孕期遺傳疾病篩檢的重點還在於及早發現與妊娠相關的問題。新一代定序有助於新生兒產前篩檢,檢測所有染色體的非整倍體(如唐氏症和 21 三體性)或部分染色體異常(重複或缺失)的敏感度超過 95%。螢光原位雜合技術(FISH)用於檢測鐮狀細胞性貧血等單基因疾病;它還有助於有效的植入前遺傳學診斷。使用母體血漿進行無細胞胎兒 DNA 等非侵入性操作是基因檢測的最新進展。胚胎 DNA 可以根據大小差異與母體 DNA 片段區分開來。使用螢光探針的即時 PCR、鳥槍定序(Solexa 或 Illumina)或大規模標靶平行定序可用於檢查與胎兒健康狀況相關的 DNA。如果進一步研究這種類型的基因篩檢,這將使醫生能夠透過某些藥物療法(藥物遺傳學)提供早期分子干涉,並在物理和化學上改造細胞、組織和器官。因此,嬰兒遺傳性疾病篩檢方法的進步為整個新生兒篩檢市場帶來了巨大的潛力。
南美洲和中美洲新生兒篩檢市場概述
南美洲和中美洲的新生兒篩檢市場分為巴西、阿根廷以及南美洲和中美洲的其他地區。南美洲和中美洲是一個由 20 個在地理區域、人口、經濟、社會、種族和發達的醫療保健系統方面多元化的國家組成的地區。與高收入國家相比,巴西、阿根廷和其他南美洲和中美洲國家接受的新生兒篩檢計畫相對較少。這主要是由於該地區各國的經濟、技術和後勤限制以及社會、文化和政治背景的差異。聯邦新生兒篩檢 (NBS) 計畫目前包括六種疾病:先天性甲狀腺功能低下症、囊性纖維化、半乳糖血症測試、生物素酶缺乏症和該地區的先天性腎上腺增生症。此外,該地區的新生兒篩檢計畫和能力正在不斷改進。智利、哥斯達黎加、古巴和烏拉圭的長期 NBS 計劃涵蓋了 99% 以上的新生兒。巴西、墨西哥和阿根廷的計畫增加了篩選小組,但需要教育、後續行動、立法和管理方面的改進。
巴西於 2001 年啟動了全國 NBS 計劃,參考中心覆蓋了 80% 以上的新生兒。該計畫包括六種主要病症:苯酮尿症、先天性甲狀腺功能低下症、血紅蛋白疾病、囊性纖維化、先天性腎上腺增生和生物素酶缺乏症。巴西國家新生兒篩檢計畫的目標是在未來幾年內達到 100% 的活產率。該國還在一些州透過串聯質譜儀 (TMS) 篩檢實施了針對其他代謝紊亂的擴展 NBS (ENBS)。巴西政府當局於 2021 年 6 月通過了一項法律,要求所有州在 2022 年 6 月之前實施 ENBS,並逐步擴大該計劃以涵蓋溶酶體疾病、免疫缺陷和脊髓性肌肉萎縮症。因此,由於新計劃的實施、醫療保健覆蓋率的提高、國家統計局新法律的頒布、疾病範圍的擴大以及公眾參與度的提高,該國在過去幾年中實現了顯著且持續的成長。政府和公共衛生當局。增加 NBS/ENBS 計劃的採用可促進新生兒的早期診斷和治療,這已被證明是改善患者健康結果的第一步。
南美洲和中美洲新生兒篩檢市場收入及 2030 年預測(百萬美元)
南美洲和中美洲新生兒篩檢市場細分
南美洲和中美洲新生兒篩檢市場根據產品類型、技術、測試類型、最終用戶和國家進行細分。
根據產品類型,南美洲和中美洲新生兒篩檢市場分為試劑、檢測試劑盒和儀器。到2022 年,試劑和檢測試劑盒細分市場將在南美洲和中美洲新生兒篩檢市場中佔據更大佔有率。酶檢測。儀器部分細分為新生兒疾病篩檢儀器、脈搏血氧儀、新生兒聽力篩檢儀器和其他儀器。
在技術方面,南美洲和中美洲新生兒篩檢市場分為串聯質譜(TMS)、分子檢測、免疫檢測和酵素檢測、脈搏血氧飽和度篩檢技術和其他技術。 2022 年,脈搏血氧飽和度篩檢技術領域佔據南美洲和中美洲新生兒篩檢市場最大佔有率。
根據測試類型,南美洲和中美洲新生兒篩檢市場分為乾血斑測試、聽力篩檢測試、危重先天性心臟病(CCHD)測試和其他測試類型。 2022 年,乾血斑檢測領域佔據南美洲和中美洲新生兒篩檢市場最大佔有率。
依最終用戶分類,南美洲和中美洲新生兒篩檢市場分為醫院、診所和診斷實驗室。 2022 年,醫院和診所細分市場在南美洲和中美洲新生兒篩檢市場中佔據更大佔有率。
根據國家/地區,南美洲和中美洲新生兒篩檢市場分為巴西、阿根廷以及南美洲和中美洲其他地區。 2022 年,巴西在南美洲和中美洲新生兒篩檢市場佔據主導地位。
Bio-Rad Laboratories Inc、Masimo Corp、Medtronic Plc、PerkinElmer Inc 和 Waters Corp 是南美洲和中美洲新生兒篩檢市場的一些領先公司。
表中的內容
The South & Central America newborn screening market was valued at US$ 58.08 million in 2022 and is expected to reach US$ 100.64 million by 2030; it is estimated to grow at a CAGR of 7.1% from 2022 to 2030.
Genetic Screening of Newborns Fuels the South & Central America Newborn Screening Market
The demand for comprehensive genetic screening of newborns is rising with the deepening knowledge about the genetic causes of medical conditions and advancements in healthcare technologies. As a result, companies in the newborn screening market are developing innovative, cost-effective screening solutions. Yescarta and Zynteglo are two examples of authorized gene treatments for large B-cell lymphoma and beta-thalassemia. Further, the emergence of technologies conferring an ability to identify genetic predispositions to diseases at birth pave the way for personalized healthcare, aligning with the broader trend of precision medicine.
Screening for genetic diseases during pregnancy also focuses on the early detection of pregnancy-related problems. Next-generation sequencing aids in the prenatal screening of neonates with a sensitivity of above 95% for detecting aneuploidies (such as Down syndrome and Trisomy 21) or partial chromosomal abnormalities (duplications or deletions) in all chromosomes. Fluorescence in-situ hybridization (FISH) is employed to detect monogenic illnesses such as sickle cell anemia; it also aids in an effective preimplantation genetic diagnosis. Noninvasive procedures such as the cell-free fetal DNA approach using maternal plasma are the recent advancements in genetic tests. The embryonic DNA can be distinguished from maternal DNA pieces based on differences in their sizes. Real-time PCR with fluorescent probes, shotgun sequencing (Solexa or Illumina), or huge targeted parallel sequencing can be used to examine DNA associated with fetal medical conditions. This would allow doctors to provide early molecular interventions with certain pharmacological therapies (pharmacogenetics) and to transform cells, tissues, and organs physically and chemically if this type of genetic screening is further researched. Thus, advancements in methods for screening infants for genetic disorders hold immense potential for the overall newborn screening market.
South & Central America Newborn Screening Market Overview
The newborn screening market in South & Central America is segmented into Brazil, Argentina, and the Rest of South & Central America. South & Central America is a region comprising 20 diversified countries in terms of geographic area, demographics, economy, society, ethnicity, and developing healthcare systems. Brazil, Argentina, and other South & Central American countries receive a comparatively low number of newborn screening programs than higher-income nations. This is mainly due to the economic, technical, and logistical constraints and differences in the social, cultural, and political backgrounds of each country in the region. The federal NewBorn Screening (NBS) program currently includes six conditions: Congenital Hypothyroidism, Cystic Fibrosis, galactosemia test, biotinidase deficiency, and Congenital Adrenal Hyperplasia in the region. Moreover, the newborn screening programs and capabilities in the region are continuously improving. Longstanding NBS programs in Chile, Costa Rica, Cuba, and Uruguay cover over 99% of newborns. The programs in Brazil, Mexico, and Argentina have increased their screening panels but require education, follow-up, legislation, and management improvements.
Brazil started its nationwide NBS program in 2001 with reference centers that covered more than 80% of newborns. This program includes six main conditions: Phenylketonuria, Congenital Hypothyroidism, hemoglobinopathies, Cystic Fibrosis, Congenital Adrenal Hyperplasia, and biotinidase deficiency. The National Neonatal Screening Program in Brazil is targeting to reach 100% of live births over the next few years. The country has also implemented the Extended NBS (ENBS) for other metabolic disorders through tandem mass spectrometer (TMS) screening in a few states. A law was passed in June 2021 by the government authority of Brazil, mandating that all states implement ENBS by June 2022, with a progressive expansion of the program to include lysosomal diseases, immunodeficiencies, and spinal muscular atrophy. Thus, the country has witnessed significant and sustained growth in the last few years, owing to the implementation of new programs, a rise in medical healthcare coverage, the enactment of new NBS laws, the expansion of the disease panel, and the higher involvement of government and public health authorities. Increasing the adoption of NBS/ENBS programs promotes early diagnosis and treatment in neonates, which prove to be the first step to improving health outcomes for patients.
South & Central America Newborn Screening Market Revenue and Forecast to 2030 (US$ Million)
South & Central America Newborn Screening Market Segmentation
The South & Central America newborn screening market is segmented based on product type, technology, test type, end user, and country.
Based on product type, the South & Central America newborn screening market is bifurcated into reagents and assay kits, and instruments. The reagents and assay kits segment held a larger South & Central America newborn screening market share in 2022. The reagents and assay kits segment is subsegmented into DNA-based assays, and immunoassays and enzymatic assays. Instruments segment is subsegmented into newborn disorder screening instruments, pulse oximeters, newborn hearing screening instruments, and other instruments.
In terms of technology, the South & Central America newborn screening market is categorized into tandem mass spectrometry (TMS), molecular assays, immunoassays and enzymatic assay, pulse oximetry screening technology, and other technologies. The pulse oximetry screening technology segment held the largest South & Central America newborn screening market share in 2022.
Based on test type, the South & Central America newborn screening market is categorized into dry blood spot test, hearing screen test, critical congenital heart diseases (CCHD) test, and other test types. The dry blood spot test segment held the largest South & Central America newborn screening market share in 2022.
By end user, the South & Central America newborn screening market is segmented into hospitals and clinics and diagnostic laboratories. The hospitals and clinics segment held a larger South & Central America newborn screening market share in 2022.
Based on country, the South & Central America newborn screening market is categorized into Brazil, Argentina, and the Rest of South & Central America. Brazil dominated the South & Central America newborn screening market in 2022.
Bio-Rad Laboratories Inc, Masimo Corp, Medtronic Plc, PerkinElmer Inc, and Waters Corp are some of the leading companies operating in the South & Central America newborn screening market.
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