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1493513

聚乙二醇化蛋白質市場 - 全球產業規模、佔有率、趨勢、機會和預測，按產品（消費品、服務）、蛋白質類型、應用、最終用途、地區和競爭細分，2019-2029F

PEGylated Proteins Market - Global Industry Size, Share, Trends, Opportunity, and Forecast, Segmented By Product (Consumable, Services), By Protein Type, By Application, By End-Use, By Region, and By Competition, 2019-2029F
出版日期: | 出版商: TechSci Research | 英文 186 Pages | 商品交期: 2-3個工作天內

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簡介目錄

2023 年全球聚乙二醇化蛋白質市場價值為9.4971 億美元，預計到2029 年預測期內將以9.82% 的複合年成長率穩步成長。連接到蛋白質分子上的生物共軛物。這個過程稱為聚乙二醇化，可改變蛋白質的理化性質，進而增強藥物動力學、降低免疫原性並提高治療效果。聚乙二醇化涉及將聚乙二醇聚合物鏈附著到蛋白質分子表面上的特定胺基酸殘基。這可以透過各種化學綴合方法來實現，包括胺反應化學、硫醇反應化學和生物正交反應，取決於蛋白質和 PEG 分子上存在的官能基。聚乙二醇化增加了蛋白質的流體動力學大小和分子量，導致腎臟濾過減少和蛋白質分解分解。

市場概況
預測期 2025-2029
2023 年市場規模 94971萬美元
2029 年市場規模 16.5968億美元
2024-2029 年複合年成長率 9.82%
成長最快的細分市場 服務
最大的市場 北美洲

與非聚乙二醇化蛋白相比，聚乙二醇化蛋白在血流中的循環時間較長，清除率較低，半衰期較長。這可以減少給藥間隔和持續的藥物暴露，從而提高治療效果和患者的依從性。聚乙二醇化透過保護蛋白質免受生理環境中的酵素分解、化學變性和聚集來賦予蛋白質穩定性。親水性 PEG 鏈在蛋白質核心周圍形成水合層，穩定其天然構形並在配製、儲存和給藥過程中保留其生物活性。這種增強的穩定性提高了聚乙二醇化蛋白質療法的保存期限和可靠性。

聚乙二醇化透過延長蛋白質的循環半衰期、降低免疫原性和增強生理環境中的穩定性來改善蛋白質的藥物動力學特性。與非聚乙二醇化蛋白質相比，聚乙二醇化蛋白質表現出更長的功效並降低了給藥頻率，提供了顯著的臨床益處並提高了患者的依從性。聚乙二醇化蛋白質被用作藥物遞送系統的載體，使治療劑能夠靶向和受控地釋放到特定組織或細胞。

聚乙二醇化可增強藥物的溶解度、生物利用度和組織滲透性，促進藥物遞送至疾病部位，同時最大限度地減少脫靶效應和全身毒性。蛋白質工程、綴合化學和藥物製劑技術的不斷進步加速了新型聚乙二醇化蛋白質的開發，其具有改善的治療特性和增強的功能。聚乙二醇化技術和連接化學的創新能夠精確控制藥物釋放動力學和位點特異性靶向，從而擴大了聚乙二醇化蛋白在多種疾病適應症中的治療潛力。

主要市場促進因素

技術進步

增強的藥物動力學特性

擴大藥物傳遞領域的應用

主要市場挑戰

免疫原性問題

來自生物相似藥和學名藥的競爭

主要市場趨勢

增加治療應用

細分市場洞察

產品洞察

蛋白質類型見解

區域洞察

目錄

第 1 章：產品概述

第 2 章：研究方法

第 3 章：執行摘要

第 4 章：客戶之聲

第 5 章：全球聚乙二醇化蛋白市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 按產品（消費品、服務）
    • 依蛋白質類型（集落刺激因子、干擾素、促紅血球生成素、單株抗體、重組因子 VII 等）
    • 依應用分類（癌症治療、肝炎、慢性腎臟病、血友病、多發性硬化症、胃腸道疾病等）
    • 依最終用途（製藥、生技公司、CRO 和學術研究機構等）
    • 按地區
    • 按公司分類 (2023)
  • 市場地圖

第 6 章：北美聚乙二醇化蛋白市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 按產品分類
    • 依蛋白質類型
    • 按申請
    • 按最終用途
    • 按國家/地區
  • 北美：國家分析
    • 美國
    • 加拿大
    • 墨西哥

第 7 章：歐洲聚乙二醇化蛋白市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 按產品分類
    • 依蛋白質類型
    • 按申請
    • 按最終用途
    • 按國家/地區
  • 歐洲：國家分析
    • 德國
    • 英國
    • 義大利
    • 法國
    • 西班牙

第 8 章：亞太地區聚乙二醇化蛋白市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 按產品分類
    • 依蛋白質類型
    • 按申請
    • 按最終用途
    • 按國家/地區
  • 亞太地區：國家分析
    • 中國
    • 印度
    • 日本
    • 韓國
    • 澳洲

第 9 章：南美洲聚乙二醇化蛋白市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 按產品分類
    • 依蛋白質類型
    • 按申請
    • 按最終用途
    • 按國家/地區
  • 南美洲：國家分析
    • 巴西
    • 阿根廷
    • 哥倫比亞

第 10 章：中東和非洲聚乙二醇化蛋白市場展望

  • 市場規模及預測
    • 按價值
  • 市佔率及預測
    • 按產品分類
    • 依蛋白質類型
    • 按申請
    • 按最終用途
    • 按國家/地區
  • MEA：國家分析
    • 南非
    • 沙烏地阿拉伯
    • 阿拉伯聯合大公國

第 11 章：市場動態

  • 促進要素
  • 挑戰

第 12 章：市場趨勢與發展

  • 併購（如有）
  • 產品發布（如有）
  • 最近的發展

第 13 章：波特的五力分析

  • 產業競爭
  • 新進入者的潛力
  • 供應商的力量
  • 客戶的力量
  • 替代產品的威脅

第14章：競爭格局

  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • Celares GmbH
  • Quanta BioDesign, Ltd
  • Biomatrik Inc
  • Laysan Bio Inc.
  • Iris Biotech GMBH
  • Valley Proteins, Inc.
  • Enzon Pharamaceuticals, Inc
  • Takeda Pharmaceuticals Company Limited

第 15 章：策略建議

第16章調查會社について,免責事項

簡介目錄
Product Code: 24049

Global PEGylated Proteins Market was valued at USD 949.71 million in 2023 and is expected to experience a steady growth in the forecast period at a CAGR of 9.82% through 2029. PEGylated proteins are bioconjugates where polyethylene glycol (PEG) chains are covalently attached to protein molecules. This process, known as PEGylation, modifies the physicochemical properties of proteins, leading to enhanced pharmacokinetics, reduced immunogenicity, and improved therapeutic efficacy. PEGylation involves the attachment of PEG polymer chains to specific amino acid residues on the surface of protein molecules. This can be achieved through various chemical conjugation methods, including amine-reactive chemistry, thiol-reactive chemistry, and bio orthogonal reactions, depending on the functional groups present on both the protein and the PEG molecule. PEGylation increases the hydrodynamic size and molecular weight of proteins, leading to decreased renal filtration and proteolytic degradation.

Market Overview
Forecast Period2025-2029
Market Size 2023USD 949.71 Million
Market Size 2029USD 1,659.68 Million
CAGR 2024-20299.82%
Fastest Growing SegmentServices
Largest MarketNorth America

PEGylated proteins exhibit prolonged circulation times in the bloodstream, with reduced clearance rates and extended half-lives compared to their non-PEGylated counterparts. This allows for less frequent dosing intervals and sustained drug exposure, improving therapeutic efficacy and patient compliance. PEGylation confers stability to proteins by protecting them from enzymatic degradation, chemical denaturation, and aggregation in physiological environments. The hydrophilic PEG chains create a hydrated layer around the protein core, stabilizing its native conformation and preserving its biological activity during formulation, storage, and administration. This enhanced stability enhances the shelf life and reliability of PEGylated protein therapeutics.

PEGylation improves the pharmacokinetic properties of proteins by extending their circulating half-life, reducing immunogenicity, and enhancing stability in physiological environments. PEGylated proteins exhibit prolonged efficacy and reduced dosing frequency compared to their non-PEGylated counterparts, offering significant clinical benefits and improved patient compliance. PEGylated proteins are utilized as carriers for drug delivery systems, enabling targeted and controlled release of therapeutic agents to specific tissues or cells.

PEGylation enhances the solubility, bioavailability, and tissue penetration of drugs, facilitating their delivery to disease sites while minimizing off-target effects and systemic toxicity. Ongoing advancements in protein engineering, conjugation chemistry, and drug formulation technologies have accelerated the development of novel PEGylated proteins with improved therapeutic properties and enhanced functionality. Innovations in PEGylation techniques and linker chemistries enable precise control over drug release kinetics and site-specific targeting, expanding the therapeutic potential of PEGylated proteins across diverse disease indications.

Key Market Drivers

Technological Advancements

Protein engineering techniques enable the design and modification of PEGylated proteins to enhance their stability under various physiological conditions. By introducing specific amino acid substitutions or structural modifications, engineers can mitigate protein degradation and improve product shelf life, thereby increasing the attractiveness of PEGylated proteins for therapeutic applications. Protein engineering allows for the precise tuning of pharmacokinetic properties such as circulating half-life and biodistribution of PEGylated proteins. Through rational design and molecular modeling approaches, researchers can tailor the size, charge, and hydrophilicity of PEG moieties to optimize drug pharmacokinetics, resulting in prolonged circulation times and improved therapeutic efficacy.

One of the challenges associated with protein therapeutics, including PEGylated proteins, is immunogenicity, which can lead to adverse immune reactions and treatment discontinuation. Protein engineering strategies enable the identification and elimination of immunogenic epitopes while preserving protein functionality, thereby reducing the risk of immune responses, and enhancing patient safety. Traditional PEGylation methods often result in heterogeneous product mixtures with variable drug conjugation sites and functional activity. Advances in protein engineering facilitate site-specific PEGylation, enabling precise attachment of PEG moieties to predetermined locations on the protein surface. Site-specific PEGylation enhances product consistency, purity, and therapeutic performance, driving adoption in the biopharmaceutical industry.

Protein engineering enables the design of multi-functional PEGylated proteins with diverse biological activities and therapeutic modalities. By incorporating targeting ligands, enzymatic payloads, or fusion domains into PEGylated protein scaffolds, engineers can create multifunctional biologics capable of targeting specific tissues, modulating immune responses, or exerting synergistic therapeutic effects, expanding the scope of applications in drug delivery and disease treatment. Advances in high-throughput screening techniques and directed evolution methodologies accelerate the discovery and optimization of PEGylated proteins with desired pharmacological properties.

Through iterative cycles of mutagenesis, selection, and screening, researchers can engineer PEGylated proteins with enhanced affinity, specificity, and stability, facilitating the development of next-generation biologics with improved clinical performance. Combinatorial approaches and synthetic biology techniques enable the rapid generation of diverse PEGylated protein libraries for screening and optimization. By harnessing the power of synthetic biology tools such as gene synthesis, DNA shuffling, and protein display technologies, scientists can explore vast sequence space and identify novel PEGylated protein variants with tailored functionalities and therapeutic profiles, driving innovation in drug discovery and development. This factor will help in the development of the Global PEGylated Proteins Market.

Enhanced Pharmacokinetic Properties

PEGylation, the process of attaching polyethylene glycol (PEG) chains to proteins, imparts steric hindrance and increases the hydrodynamic volume of proteins. This modification reduces renal clearance and proteolytic degradation of proteins, resulting in prolonged circulation times in the bloodstream. PEGylated proteins exhibit slower clearance rates compared to their non-PEGylated counterparts, leading to extended therapeutic effects and reduced dosing frequency. PEGylation enhances the bioavailability of proteins by protecting them from enzymatic degradation and immune recognition in the bloodstream. The covalent attachment of PEG chains shields protein antigens from proteases and immunoglobulins, thereby reducing their clearance and degradation rates. This increased stability and bioavailability result in higher systemic exposure to therapeutic proteins, maximizing their pharmacological effects and therapeutic outcomes.

PEGylated proteins possess improved tissue penetration and distribution characteristics compared to unmodified proteins. The hydrated PEG chains create a hydrophilic "brush" layer around the protein surface, preventing non-specific interactions with plasma proteins and cell membranes. This stealth effect enables PEGylated proteins to penetrate deep into target tissues and reach intracellular compartments more efficiently, enhancing their therapeutic efficacy in treating localized and systemic diseases.

PEGylation reduces the immunogenicity of therapeutic proteins by masking antigenic epitopes and minimizing immune recognition and clearance. The PEG chains act as "stealth" coatings that camouflage the protein surface from immune surveillance, thereby reducing the risk of immune responses and neutralizing antibodies. This decreased immunogenicity enhances the safety and tolerability of PEGylated proteins, allowing for repeated administration and prolonged treatment regimens without eliciting adverse immune reactions. PEGylation enables the customization of pharmacokinetic profiles to meet specific therapeutic requirements and patient needs.

By varying the size, structure, and density of PEG chains, researchers can modulate the rate of renal excretion, tissue distribution, and metabolic clearance of PEGylated proteins. This tunable pharmacokinetics allows for precise control over drug exposure levels and duration of action, optimizing therapeutic efficacy while minimizing off-target effects and toxicity. The extended half-life and reduced dosing frequency of PEGylated proteins enhance patient convenience and compliance with treatment regimens. Patients receiving PEGylated protein therapies require fewer injections or infusions, resulting in reduced treatment burden, improved adherence, and better overall clinical outcomes. This dosing convenience contributes to patient satisfaction and acceptance of PEGylated protein therapies as preferred treatment options for chronic and debilitating diseases. This factor will pace up the demand of the Global PEGylated Proteins Market.

Expanding Applications in Drug Delivery

PEGylation enhances the pharmacokinetic properties of proteins by increasing their circulating half-life and reducing renal clearance. This extended circulation time allows for sustained drug release and prolonged therapeutic effects, making PEGylated proteins well-suited for drug delivery applications requiring controlled release and systemic exposure. PEGylation confers stability to proteins, protecting them from enzymatic degradation and denaturation in biological fluids and harsh physiological environments. PEGylated proteins exhibit improved stability during storage, transportation, and administration, enabling formulation as long-acting injectables, depot formulations, or sustained-release formulations for controlled drug delivery. PEGylated proteins can be engineered to target specific tissues, cells, or receptors through ligand-receptor interactions or receptor-mediated endocytosis.

By conjugating targeting ligands or antibodies to PEGylated proteins, drug delivery systems can achieve site-specific accumulation and enhanced therapeutic efficacy while minimizing off-target effects and systemic toxicity. PEGylation enhances the tissue penetration and distribution of proteins by reducing non-specific interactions with plasma proteins and extracellular matrix components. PEGylated proteins can penetrate deep into tumor tissues, inflamed tissues, or physiological barriers such as the blood-brain barrier, facilitating drug delivery to target sites and overcoming biological barriers that limit therapeutic access.

PEGylation reduces the immunogenicity and antigenicity of proteins, minimizing immune responses and adverse reactions upon administration. This enhanced biocompatibility and reduced toxicity profile make PEGylated proteins ideal candidates for drug delivery systems, enabling safe and well-tolerated administration routes such as parenteral injection, oral delivery, nasal delivery, or pulmonary delivery. PEGylated proteins offer versatile formulation options for drug delivery applications, including nanoparticles, micelles, liposomes, hydrogels, and polymer conjugates. These formulation platforms can encapsulate, stabilize, and deliver therapeutic payloads while providing tunable release kinetics, sustained drug release profiles, and improved bioavailability for a wide range of small molecules, peptides, and biologics.

PEGylation enables the customization of drug delivery systems to meet specific therapeutic requirements and patient needs. By modulating the size, shape, surface charge, and PEGylation density of delivery vehicles, researchers can tailor drug pharmacokinetics, biodistribution, and release kinetics to optimize therapeutic outcomes and minimize side effects in targeted patient populations. This factor will accelerate the demand of the Global PEGylated Proteins Market.

Key Market Challenges

Immunogenicity Concerns

PEGylation involves conjugating PEG chains to proteins. While PEGylation can shield proteins from immune recognition, the protein component of PEGylated proteins may still elicit immune responses, especially if it's foreign or derived from non-human sources. These immune responses can range from mild allergic reactions to more severe immune-mediated adverse events. Immune responses against PEGylated proteins can lead to their accelerated clearance from the bloodstream or neutralization of their therapeutic activity. This can result in reduced efficacy and treatment failure, particularly in patients requiring long-term or repeated administration of PEGylated protein therapies.

Immunogenicity can have significant clinical implications for patient safety and treatment outcomes. Immune reactions to PEGylated proteins may manifest as infusion reactions, hypersensitivity responses, or autoimmune phenomena, necessitating close monitoring, dose adjustments, or discontinuation of therapy in affected individuals. Although PEG is considered biocompatible and has been used extensively in pharmaceuticals, some individuals may develop antibodies against PEG. This can lead to hypersensitivity reactions and reduced efficacy of PEGylated proteins over time. The prevalence and clinical significance of anti-PEG antibodies are still being studied, but they represent a potential safety concern.

Competition from Biosimilars and Generics

As patents for original PEGylated protein drugs expire, they become vulnerable to competition from biosimilar and generic manufacturers. Once market exclusivity ends, biosimilar and generic versions of PEGylated proteins can enter the market, offering similar therapeutic effects at potentially lower prices. The introduction of biosimilars and generics often leads to price erosion and cost pressures in the PEGylated proteins market. Increased competition among manufacturers drives down prices, resulting in reduced profit margins for originator companies and price-based competition among biosimilar and generic products. The availability of multiple biosimilar and generic versions of PEGylated proteins can lead to market saturation and fragmentation. With numerous competing products available, healthcare providers and payers face challenges in selecting and managing treatment options, leading to increased complexity and administrative burden in healthcare decision-making.

Biosimilar and generic versions of PEGylated proteins must demonstrate similarity in terms of safety, efficacy, and quality compared to the reference product. Concerns regarding the analytical similarity, immunogenicity, and manufacturing processes of biosimilars and generics may arise, potentially impacting physician and patient confidence in their therapeutic equivalence and interchangeability. Established brand loyalty and physician preference for originator PEGylated protein drugs may pose barriers to the adoption of biosimilars and generics. Physicians may hesitate to switch patients from familiar branded products to biosimilar or generic alternatives, citing concerns about efficacy, safety, and clinical outcomes.

Key Market Trends

Increasing Therapeutic Applications

PEGylated proteins are extensively used in oncology for the treatment of various cancers. PEGylated versions of therapeutic proteins such as interferons, cytokines, and monoclonal antibodies are engineered to target tumor cells, inhibit tumor growth, and modulate the immune response against cancer. PEGylation improves the stability and half-life of anticancer agents, allowing for sustained drug exposure and enhanced therapeutic efficacy while minimizing systemic toxicity. PEGylated proteins are employed in the treatment of hematological disorders such as anemia, thrombocytopenia, and hemophilia. Erythropoietin (EPO) and granulocyte colony-stimulating factor (G-CSF) are examples of PEGylated proteins used to stimulate red blood cell and white blood cell production, respectively, in patients with anemia and neutropenia associated with cancer chemotherapy or chronic diseases.

PEGylated proteins play a vital role in the management of autoimmune disorders, including rheumatoid arthritis, multiple sclerosis, and psoriasis. PEGylated tumor necrosis factor (TNF) inhibitors and interleukin receptor antagonists are used to suppress inflammatory responses, alleviate disease symptoms, and prevent joint damage in patients with autoimmune arthritis and inflammatory bowel disease. PEGylated proteins are utilized in the treatment of metabolic disorders such as diabetes, hypercholesterolemia, and obesity. PEGylated insulin analogs and glucagon-like peptide-1 (GLP-1) receptor agonists offer improved glycemic control and weight management in patients with type 1 and type 2 diabetes mellitus, while PEGylated lipoprotein lipase (LPL) activators reduce triglyceride levels and improve lipid metabolism in patients with hypertriglyceridemia.

Segmental Insights

Product Insights

The Consumable segment is projected to experience significant dominance in the Global PEGylated Proteins Market during the forecast period. PEGylation continues to gain traction in the biopharmaceutical industry for improving the pharmacokinetic properties and therapeutic efficacy of proteins, there is a growing demand for consumables used in PEGylation processes. These consumables include PEGylation reagents, linker molecules, activated PEG derivatives, and other biochemicals necessary for protein modification and conjugation. The growing popularity of biologic therapeutics, including PEGylated proteins, drives the demand for consumables used in their manufacturing processes. Biopharmaceutical companies and contract manufacturing organizations (CMOs) require high-quality consumables and reagents to support the production of PEGylated proteins at scale, ensuring consistency, purity, and product quality throughout the manufacturing process.

The expansion of bioprocessing facilities and manufacturing capacity to meet the growing demand for biologic therapeutics contributes to increased consumption of consumables in the PEGylated proteins market. Biopharmaceutical companies invest in state-of-the-art facilities equipped with advanced bioprocessing equipment and consumables to support large-scale production of PEGylated proteins for clinical and commercial applications. Consumable suppliers and manufacturers offer customized solutions and services tailored to the specific requirements of PEGylation and protein modification applications. This includes the development of specialty reagents, kits, and consumables designed to streamline PEGylation workflows, optimize reaction conditions, and maximize yields, thereby driving efficiency and productivity in protein engineering and bioprocessing operations.

Protein Type Insights

The Colony Stimulating Factors segment is projected to experience significant growth in the Global PEGylated Proteins Market during the forecast period. Colony stimulating factors play a crucial role in stimulating the production of white blood cells, particularly neutrophils, which are often depleted during chemotherapy treatment. Chemotherapy-induced neutropenia increases the risk of infections and can lead to treatment delays or dose reductions. PEGylated CSFs offer a longer circulating half-life compared to conventional CSFs, providing sustained neutrophil support, and reducing the frequency of injections needed for patients undergoing chemotherapy. PEGylation enhances the pharmacokinetic profile of CSFs by increasing their stability and extending their circulating half-life in the bloodstream. PEGylated CSFs exhibit reduced renal clearance and proteolytic degradation, resulting in more predictable and sustained levels of neutrophil support over an extended duration.

This improved pharmacokinetic profile enhances patient convenience and compliance with treatment regimens. PEGylation can reduce the immunogenicity of CSFs by masking immunogenic epitopes and reducing antibody recognition and neutralization. This helps mitigate the risk of immune reactions and hypersensitivity responses associated with the administration of CSFs, ensuring safer and more tolerable treatment options for patients receiving chemotherapy. PEGylated CSFs offer the advantage of less frequent dosing schedules compared to conventional CSFs, reducing the burden of treatment administration, and improving patient compliance. Patients undergoing chemotherapy can benefit from fewer injections and clinic visits while receiving consistent and sustained neutrophil support throughout their treatment cycles.

Regional Insights

North America emerged as the dominant player in the Global PEGylated Proteins Market in 2023. North America, particularly the United States, is home to a robust biopharmaceutical industry with a significant focus on research and development of protein-based therapeutics. The region boasts numerous biotechnology and pharmaceutical companies that specialize in developing and commercializing biologics, including PEGylated proteins. The region's advanced healthcare infrastructure, including well-established academic and research institutions, supports innovation and collaboration in biopharmaceutical research. North America benefits from a wealth of scientific expertise and resources dedicated to advancing drug discovery and development processes.

The regulatory framework governing drug approval and commercialization in North America, particularly the United States, is well-defined and transparent. The U.S. Food and Drug Administration (FDA) provides clear guidelines and pathways for the development and regulatory approval of biologic drugs, including PEGylated proteins, which facilitates market entry for manufacturers. North America offers access to abundant capital and funding sources for biopharmaceutical research and development. Venture capital firms, private equity investors, and government funding agencies actively support biotech startups and established companies pursuing innovative therapies, including PEGylated proteins.

Key Market Players

Thermo Fisher Scientific Inc.

Merck KGaA

Celares GmbH

Quanta BioDesign, Ltd

Biomatrik Inc

Laysan Bio Inc.

Iris Biotech GMBH

Valley Proteins, Inc.

Enzon Pharamaceuticals, Inc

Takeda Pharmaceuticals Company Limited

Report Scope:

In this report, the Global PEGylated Proteins Market has been segmented into the following categories, in addition to the industry trends which have also been detailed below:

PEGylated Proteins Market, By Product:

    Consumable

PEGylation Kits Reagents

Monofunctional Linear PEGs

Bifunctional PEGs

others

PEGylation Kits

    Services

PEGylated Proteins Market, By Protein Type:

    Colony Stimulating Factors Interferons Erythropoietin mAbs Recombinant Factor VII Others

PEGylated Proteins Market, By Application:

    Cancer Treatment Hepatitis Chronic Kidney Diseases Hemophilia Multiple Sclerosis Gastrointestinal Disorders Others

PEGylated Proteins Market, By End-Use:

    Pharmaceuticals Biotechnology Companies CROs and Academic Research Institutes Others

PEGylated Proteins Market, By Region:

    North America

United States

Canada

Mexico

    Europe

Germany

United Kingdom

France

Italy

Spain

    Asia-Pacific

China

Japan

India

Australia

South Korea

    South America

Brazil

Argentina

Colombia

    Middle East & Africa

South Africa

Saudi Arabia

UAE

Competitive Landscape

Company Profiles: Detailed analysis of the major companies present in the Global PEGylated Proteins Market.

Available Customizations:

Global PEGylated Proteins market report with the given market data, Tech Sci Research offers customizations according to a company's specific needs. The following customization options are available for the report:

Company Information

Detailed analysis and profiling of additional market players (up to five).

Table of Contents

1. Product Overview

  • 1.1. Market Definition
  • 1.2. Scope of the Market
    • 1.2.1. Markets Covered
    • 1.2.2. Years Considered for Study
    • 1.2.3. Key Market Segmentations

2. Research Methodology

  • 2.1. Objective of the Study
  • 2.2. Baseline Methodology
  • 2.3. Key Industry Partners
  • 2.4. Major Association and Secondary Sources
  • 2.5. Forecasting Methodology
  • 2.6. Data Triangulation & Validation
  • 2.7. Assumptions and Limitations

3. Executive Summary

  • 3.1. Overview of the Market
  • 3.2. Overview of Key Market Segmentations
  • 3.3. Overview of Key Market Players
  • 3.4. Overview of Key Regions/Countries
  • 3.5. Overview of Market Drivers, Challenges, Trends

4. Voice of Customer

5. Global PEGylated Proteins Market Outlook

  • 5.1. Market Size & Forecast
    • 5.1.1. By Value
  • 5.2. Market Share & Forecast
    • 5.2.1. By Product (Consumable, Services)
      • 5.2.1.1. By Consumable (PEGylation Kits Reagents, PEGylation Kits)
        • 5.2.1.1.1. By PEGylation Kits Reagents (Monofunctional Linear PEGs, Bifunctional PEGs, others)
    • 5.2.2. By Protein Type (Colony Stimulating Factors, Interferons, Erythropoietin, mAbs, Recombinant Factor VII and Others)
    • 5.2.3. By Application (Cancer Treatment, Hepatitis, Chronic Kidney Diseases, Hemophilia, Multiple Sclerosis, Gastrointestinal Disorders and Others)
    • 5.2.4. By End-Use (Pharmaceuticals, Biotechnology Companies, CROs and Academic Research Institutes, others)
    • 5.2.5. By Region
    • 5.2.6. By Company (2023)
  • 5.3. Market Map

6. North America PEGylated Proteins Market Outlook

  • 6.1. Market Size & Forecast
    • 6.1.1. By Value
  • 6.2. Market Share & Forecast
    • 6.2.1. By Product
    • 6.2.2. By Protein Type
    • 6.2.3. By Application
    • 6.2.4. By End-Use
    • 6.2.5. By Country
  • 6.3. North America: Country Analysis
    • 6.3.1. United States PEGylated Proteins Market Outlook
      • 6.3.1.1. Market Size & Forecast
        • 6.3.1.1.1. By Value
      • 6.3.1.2. Market Share & Forecast
        • 6.3.1.2.1. By Product
        • 6.3.1.2.2. By Protein Type
        • 6.3.1.2.3. By Application
        • 6.3.1.2.4. By End-Use
    • 6.3.2. Canada PEGylated Proteins Market Outlook
      • 6.3.2.1. Market Size & Forecast
        • 6.3.2.1.1. By Value
      • 6.3.2.2. Market Share & Forecast
        • 6.3.2.2.1. By Product
        • 6.3.2.2.2. By Protein Type
        • 6.3.2.2.3. By Application
        • 6.3.2.2.4. By End-Use
    • 6.3.3. Mexico PEGylated Proteins Market Outlook
      • 6.3.3.1. Market Size & Forecast
        • 6.3.3.1.1. By Value
      • 6.3.3.2. Market Share & Forecast
        • 6.3.3.2.1. By Product
        • 6.3.3.2.2. By Protein Type
        • 6.3.3.2.3. By Application
        • 6.3.3.2.4. By End-Use

7. Europe PEGylated Proteins Market Outlook

  • 7.1. Market Size & Forecast
    • 7.1.1. By Value
  • 7.2. Market Share & Forecast
    • 7.2.1. By Product
    • 7.2.2. By Protein Type
    • 7.2.3. By Application
    • 7.2.4. By End-Use
    • 7.2.5. By Country
  • 7.3. Europe: Country Analysis
    • 7.3.1. Germany PEGylated Proteins Market Outlook
      • 7.3.1.1. Market Size & Forecast
        • 7.3.1.1.1. By Value
      • 7.3.1.2. Market Share & Forecast
        • 7.3.1.2.1. By Product
        • 7.3.1.2.2. By Protein Type
        • 7.3.1.2.3. By Application
        • 7.3.1.2.4. By End-Use
    • 7.3.2. United Kingdom PEGylated Proteins Market Outlook
      • 7.3.2.1. Market Size & Forecast
        • 7.3.2.1.1. By Value
      • 7.3.2.2. Market Share & Forecast
        • 7.3.2.2.1. By Product
        • 7.3.2.2.2. By Protein Type
        • 7.3.2.2.3. By Application
        • 7.3.2.2.4. By End-Use
    • 7.3.3. Italy PEGylated Proteins Market Outlook
      • 7.3.3.1. Market Size & Forecast
        • 7.3.3.1.1. By Value
      • 7.3.3.2. Market Share & Forecast
        • 7.3.3.2.1. By Product
        • 7.3.3.2.2. By Protein Type
        • 7.3.3.2.3. By Application
        • 7.3.3.2.4. By End-Use
    • 7.3.4. France PEGylated Proteins Market Outlook
      • 7.3.4.1. Market Size & Forecast
        • 7.3.4.1.1. By Value
      • 7.3.4.2. Market Share & Forecast
        • 7.3.4.2.1. By Product
        • 7.3.4.2.2. By Protein Type
        • 7.3.4.2.3. By Application
        • 7.3.4.2.4. By End-Use
    • 7.3.5. Spain PEGylated Proteins Market Outlook
      • 7.3.5.1. Market Size & Forecast
        • 7.3.5.1.1. By Value
      • 7.3.5.2. Market Share & Forecast
        • 7.3.5.2.1. By Product
        • 7.3.5.2.2. By Protein Type
        • 7.3.5.2.3. By Application
        • 7.3.5.2.4. By End-Use

8. Asia-Pacific PEGylated Proteins Market Outlook

  • 8.1. Market Size & Forecast
    • 8.1.1. By Value
  • 8.2. Market Share & Forecast
    • 8.2.1. By Product
    • 8.2.2. By Protein Type
    • 8.2.3. By Application
    • 8.2.4. By End-Use
    • 8.2.5. By Country
  • 8.3. Asia-Pacific: Country Analysis
    • 8.3.1. China PEGylated Proteins Market Outlook
      • 8.3.1.1. Market Size & Forecast
        • 8.3.1.1.1. By Value
      • 8.3.1.2. Market Share & Forecast
        • 8.3.1.2.1. By Product
        • 8.3.1.2.2. By Protein Type
        • 8.3.1.2.3. By Application
        • 8.3.1.2.4. By End-Use
    • 8.3.2. India PEGylated Proteins Market Outlook
      • 8.3.2.1. Market Size & Forecast
        • 8.3.2.1.1. By Value
      • 8.3.2.2. Market Share & Forecast
        • 8.3.2.2.1. By Product
        • 8.3.2.2.2. By Protein Type
        • 8.3.2.2.3. By Application
        • 8.3.2.2.4. By End-Use
    • 8.3.3. Japan PEGylated Proteins Market Outlook
      • 8.3.3.1. Market Size & Forecast
        • 8.3.3.1.1. By Value
      • 8.3.3.2. Market Share & Forecast
        • 8.3.3.2.1. By Product
        • 8.3.3.2.2. By Protein Type
        • 8.3.3.2.3. By Application
        • 8.3.3.2.4. By End-Use
    • 8.3.4. South Korea PEGylated Proteins Market Outlook
      • 8.3.4.1. Market Size & Forecast
        • 8.3.4.1.1. By Value
      • 8.3.4.2. Market Share & Forecast
        • 8.3.4.2.1. By Product
        • 8.3.4.2.2. By Protein Type
        • 8.3.4.2.3. By Application
        • 8.3.4.2.4. By End-Use
    • 8.3.5. Australia PEGylated Proteins Market Outlook
      • 8.3.5.1. Market Size & Forecast
        • 8.3.5.1.1. By Value
      • 8.3.5.2. Market Share & Forecast
        • 8.3.5.2.1. By Product
        • 8.3.5.2.2. By Protein Type
        • 8.3.5.2.3. By Application
        • 8.3.5.2.4. By End-Use

9. South America PEGylated Proteins Market Outlook

  • 9.1. Market Size & Forecast
    • 9.1.1. By Value
  • 9.2. Market Share & Forecast
    • 9.2.1. By Product
    • 9.2.2. By Protein Type
    • 9.2.3. By Application
    • 9.2.4. By End-Use
    • 9.2.5. By Country
  • 9.3. South America: Country Analysis
    • 9.3.1. Brazil PEGylated Proteins Market Outlook
      • 9.3.1.1. Market Size & Forecast
        • 9.3.1.1.1. By Value
      • 9.3.1.2. Market Share & Forecast
        • 9.3.1.2.1. By Product
        • 9.3.1.2.2. By Protein Type
        • 9.3.1.2.3. By Application
        • 9.3.1.2.4. By End-Use
    • 9.3.2. Argentina PEGylated Proteins Market Outlook
      • 9.3.2.1. Market Size & Forecast
        • 9.3.2.1.1. By Value
      • 9.3.2.2. Market Share & Forecast
        • 9.3.2.2.1. By Product
        • 9.3.2.2.2. By Protein Type
        • 9.3.2.2.3. By Application
        • 9.3.2.2.4. By End-Use
    • 9.3.3. Colombia PEGylated Proteins Market Outlook
      • 9.3.3.1. Market Size & Forecast
        • 9.3.3.1.1. By Value
      • 9.3.3.2. Market Share & Forecast
        • 9.3.3.2.1. By Product
        • 9.3.3.2.2. By Protein Type
        • 9.3.3.2.3. By Application
        • 9.3.3.2.4. By End-Use

10. Middle East and Africa PEGylated Proteins Market Outlook

  • 10.1. Market Size & Forecast
    • 10.1.1. By Value
  • 10.2. Market Share & Forecast
    • 10.2.1. By Product
    • 10.2.2. By Protein Type
    • 10.2.3. By Application
    • 10.2.4. By End-Use
    • 10.2.5. By Country
  • 10.3. MEA: Country Analysis
    • 10.3.1. South Africa PEGylated Proteins Market Outlook
      • 10.3.1.1. Market Size & Forecast
        • 10.3.1.1.1. By Value
      • 10.3.1.2. Market Share & Forecast
        • 10.3.1.2.1. By Product
        • 10.3.1.2.2. By Protein Type
        • 10.3.1.2.3. By Application
        • 10.3.1.2.4. By End-Use
    • 10.3.2. Saudi Arabia PEGylated Proteins Market Outlook
      • 10.3.2.1. Market Size & Forecast
        • 10.3.2.1.1. By Value
      • 10.3.2.2. Market Share & Forecast
        • 10.3.2.2.1. By Product
        • 10.3.2.2.2. By Protein Type
        • 10.3.2.2.3. By Application
        • 10.3.2.2.4. By End-Use
    • 10.3.3. UAE PEGylated Proteins Market Outlook
      • 10.3.3.1. Market Size & Forecast
        • 10.3.3.1.1. By Value
      • 10.3.3.2. Market Share & Forecast
        • 10.3.3.2.1. By Product
        • 10.3.3.2.2. By Protein Type
        • 10.3.3.2.3. By Application
        • 10.3.3.2.4. By End-Use

11. Market Dynamics

  • 11.1. Drivers
  • 11.2. Challenges

12. Market Trends & Developments

  • 12.1. Merger & Acquisition (If Any)
  • 12.2. Product Launches (If Any)
  • 12.3. Recent Developments

13. Porter's Five Forces Analysis

  • 13.1. Competition in the Industry
  • 13.2. Potential of New Entrants
  • 13.3. Power of Suppliers
  • 13.4. Power of Customers
  • 13.5. Threat of Substitute Product

14. Competitive Landscape

  • 14.1. Thermo Fisher Scientific Inc.
    • 14.1.1. Business Overview
    • 14.1.2. Company Snapshot
    • 14.1.3. Products & Services
    • 14.1.4. Financials (As Reported)
    • 14.1.5. Recent Developments
    • 14.1.6. Key Personnel Details
    • 14.1.7. SWOT Analysis
  • 14.2. Merck KGaA
  • 14.3. Celares GmbH
  • 14.4. Quanta BioDesign, Ltd
  • 14.5. Biomatrik Inc
  • 14.6. Laysan Bio Inc.
  • 14.7. Iris Biotech GMBH
  • 14.8. Valley Proteins, Inc.
  • 14.9. Enzon Pharamaceuticals, Inc
  • 14.10.Takeda Pharmaceuticals Company Limited

15. Strategic Recommendations

16. About Us & Disclaimer