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市場調查報告書
商品編碼
1673815

製藥和生物技術行業探索階段合作條款和協議（2020-2025年）

Discovery Stage Partnering Terms and Agreements in Pharma and Biotech 2020-2025
出版日期: | 出版商: Current Partnering | 英文 2500+ Pages | 商品交期: 最快1-2個工作天內

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簡介目錄

本報告研究了製藥和生物技術行業的探索階段合作條款和協議，並提供了全面的資料驅動分析，說明公司如何以及為何簽訂探索階段合作協議，以及這些協議所依據的財務和戰略條款。本報告還深入洞察了製藥和生物技術產業早期聯盟的結構、談判動態和財務考量。

在藥物探索階段，授權協議通常授予被授權人進一步開發授權人的產品或技術的權利或選擇權。這些協議通常包含多個部分，從合作研究與開發（R&D）開始，並可能達成商業化協議。

本報告詳細分析了醫療保健領域最新的探索階段交易，以幫助公司了解市場趨勢，評估競爭對手的交易結構，並最佳化自己的談判策略。

本報告提供：

  • 2020年及以後生物製藥產業藥物探索階段交易趨勢分析
  • 了解財務結構，包括預付款、里程碑付款和特許權使用費
  • 真實藥物探索階段合約案例研究
  • 可存取 2,690 多個探索階段交易（如有交易記錄，另行提供）
  • 2020年及以後最活躍的藥物發現交易者簡介
  • 對最高價值藥物探索階段交易的詳細分析

目錄

執行摘要

第1章 簡介

第2章 為什麼企業在臨床階段合作

  • 合作在藥物研發中的作用
    • 探索階段的許可
    • 探索階段的許可
  • 區分發現、臨床前和臨床階段的交易
  • 在藥物研發過程中簽訂合作協議的原因
    • 授權商為何參與探索階段的交易
    • 為什麼被授權人參與探索階段的交易
  • 探索階段合作交易的未來

第3章 探索階段的交易策略與結構

  • 公司在什麼階段進行合作？
    • 製藥/生技領域的早期合作
    • 製藥/生技聯盟
  • 早期與晚期夥伴關係：風險與成本
  • 各公司在發現、臨床前和臨床階段合作上花了多少？
  • 純合作協議與多部分合作協議
  • 純許可合約結構
    • 純許可協議範例
    • 個案研究
  • 多部分藥物探索階段合作協議
    • 多部分早期條款範例
    • 個案研究

第4章 探索階段夥伴關係的付款策略

  • 探索階段的支付策略
  • 付款方式
    • 標題
    • 預付
    • 貸款
    • 可轉換貸款
    • 公平
    • 研發資金
    • 許可證費用
    • 里程碑
    • 版稅
    • 現金
    • 選擇

第5章 探索階段交易趨勢

  • 長期探索階段夥伴關係
  • 探索階段合作夥伴關係（依交易類型）
  • 依疾病類型的探索階段夥伴關係
  • 依技術類型的藥物探索階段合作夥伴關係
  • 最活躍的企業探索階段合作

第6章 探索階段夥伴關係的付款條款

  • 探索階段的付款條款指南
    • 預付
    • 里程碑
    • 版稅
  • 藥物研發中的付款條款：交易資料分析
    • 公開資料
    • 調查資料
  • 付款條件分析
    • 探索階段的主要資料
    • 探索階段交易的預付款
    • 藥物探索階段交易的里程碑付款
    • 藥物研發過程中的專利費率

第7章 關鍵探索階段交易

  • 價值最高的探索階段交易

第8章 25 大藥物研發交易者

  • 25 位最活躍的探索階段交易者

第9章 探索階段合作協議目錄

  • 2020年至2025年的探索階段交易

第10章 探索階段交易：依開發階段

  • 依探索階段的交易

附錄

簡介目錄
Product Code: CP2056

Global Discovery Stage Partnering Terms and Agreements in Pharma and Biotech (2020-2025)

The Global Discovery Stage Partnering Terms and Agreements in Pharma and Biotech (2020-2025) report offers a comprehensive, data-driven analysis of how and why companies engage in discovery-stage partnering deals and the financial and strategic terms underpinning these agreements. This essential industry resource provides deep insights into the structure, negotiation dynamics, and financial considerations that define early-stage partnerships in the pharmaceutical and biotech sectors.

At the discovery stage, licensing agreements typically grant the licensee rights or options to further develop a licensor's product or technology. These agreements are often multi-component, beginning with collaborative research and development (R&D) and potentially leading to commercialization agreements.

This report provides a detailed breakdown of the latest discovery-stage agreements in the healthcare sector, helping companies identify market trends, evaluate competitive deal structures, and optimize their own negotiation strategies.

A Must-Have Resource for Biotech and Pharma Dealmakers

The Global Discovery Stage Partnering Terms and Agreements in Pharma and Biotech (2020-2025) report is an indispensable resource for business development, legal, and financial professionals involved in biopharma dealmaking.

With comprehensive insights, a vast deal database, and direct access to contract documents, this report serves as the ultimate tool for:

  • Benchmarking deal structures and financial terms
  • Optimizing negotiation strategies
  • Assessing potential partners' flexibility and deal-making behavior
  • Identifying trends and best practices in discovery-stage partnerships
  • For those looking to navigate the complex landscape of discovery-stage partnering, this report offers the clarity, data, and strategic guidance needed to secure high-value agreements with the right partners.
  • Why This Report is Essential for Dealmakers
  • Gaining insight into the flexibility and negotiation strategies of potential partners is crucial in structuring a successful discovery-stage deal. While headline financial terms (e.g., upfront payments, milestones, and royalties) provide a broad overview, contract documents offer a deeper understanding of the actual triggers and conditions for these payments-critical details that press releases and traditional databases often omit.
  • This report contains a comprehensive listing of all discovery-stage partnering deals announced since 2020, including financial terms where available. It also features over 2,690 links to detailed online deal records, including publicly available contract documents filed with the SEC.
  • By analyzing these agreements, companies gain a competitive edge in structuring deals that align with industry benchmarks while maximizing potential returns.
  • Comprehensive Analysis of Discovery-Stage Partnering Trends

The first chapters of the report provide a detailed orientation to discovery-stage deal-making and strategic considerations:

Chapter 1 - Introduction to the report

Chapter 2 - Why companies engage in discovery-stage partnerships

Chapter 3 - Strategic approaches and deal structures, with case studies

Chapter 4 - Payment strategies, including upfronts, milestones, and royalties

Chapter 5 - Discovery-stage deal-making analysis (2020-2025), categorized by year, therapeutic area, technology type, and key dealmakers

Chapter 6 - Detailed analysis of financial terms, including headline values, upfront payments, milestone triggers, and royalty rates

Chapter 7 - A review of the leading discovery-stage deals by headline value

Chapter 8 - The top 25 most active discovery-stage dealmakers

Chapter 9 - A database of discovery-stage partnering agreements, including contract documents where available

Chapter 10 - A comprehensive directory of all discovery-stage deals announced since 2020

  • Each deal record is linked to Current Agreements, a proprietary database that provides easy access to full deal structures, financial terms, and contract documents.
  • Key Benefits of the Report
  • Comprehensive insights into discovery-stage deal trends since 2020
  • Access to key financial terms, including headline values, upfronts, milestones, and royalty structures
  • Breakdown of deal structures, with real-world case studies
  • Analysis of contractual terms, including real-world clause examples
  • Benchmarking of deal terms based on actual agreements
  • Due diligence insights to assess the suitability of proposed deal terms for potential partners
  • Scope of the Report

The Global Discovery Stage Partnering Terms and Agreements in Pharma and Biotech (2020-2025) report provides:

  • Analysis of discovery-stage dealmaking trends in the biopharma industry since 2020
  • Insight into financial structures, including upfront, milestone, and royalty payments
  • Case studies of real-life discovery-stage agreements
  • Access to over 2,690 discovery-stage deals, with contract records where available
  • Profiles of the most active discovery-stage dealmakers since 2020
  • Detailed analysis of the highest-value discovery-stage deals

Each deal record is indexed by:

  • Company (A-Z)
  • Headline Value
  • Stage of Development at Signing
  • Deal Type
  • Specific Therapy Focus
  • For easy access, every deal record links to an online version, and where available, the full contract document.
  • Critical Questions Answered

By analyzing actual contract agreements where available, this report provides definitive answers to critical questions such as:

  • What specific rights are granted in each agreement?
  • What exclusivity terms apply?
  • How is the deal structured financially? (Upfronts, milestones, royalties)
  • How are sales and payments audited?
  • Who controls development, manufacturing, and commercialization?
  • How is intellectual property handled?
  • How are confidentiality and publication rights managed?
  • Under what conditions can a deal be terminated?
  • What dispute resolution mechanisms are in place?
  • What happens in the event of a change in ownership?
  • Gain the competitive edge-explore the report today.

Table of Contents

Executive Summary

Chapter 1 - Introduction

Chapter 2 - Why do companies partner at discovery stage?

  • 2.1. Introduction
  • 2.2. The role of discovery stage partnering
    • 2.2.1. In-licensing at discovery stage
    • 2.2.2. Out-licensing at discovery stage
  • 2.3. Difference between discovery, preclinical and clinical stage deals
  • 2.4. Reasons for entering into discovery stage partnering deals
    • 2.4.1. Licensors reasons for entering discovery stage deals
    • 2.4.2. Licensees reasons for entering discovery stage deals
  • 2.5. The future of discovery stage partnering deals

Chapter 3 - Discovery stage deal strategies and structure

  • 3.1. Introduction
  • 3.2. At what stage do companies partner?
    • 3.2.1. Partnering early in pharmaceutical/biotech
    • 3.2.1.1. Discovery and preclinical stage partnering case studies
    • 3.2.1.1.a. Case study 1
    • 3.2.1.1.b. Case study 2
    • 3.2.1.1.c. Case study 3
    • 3.2.1.1.d. Case study 4
    • 3.2.2. Partnering later in pharmaceutical/biotech
    • 3.2.2.1. Clinical stage partnering case studies
    • 3.2.2.1.a. Case study 5
    • 3.2.2.1.b. Case study 6
    • 3.2.2.1.c. Case study 7
    • 3.2.2.1.d. Case study 8
  • 3.3. Early and later stage partnering - a risk/cost comparison
  • 3.4. What do companies spend on discovery, preclinical and clinical stage partnering?
  • 3.5. Pure versus multi-component partnering deals
  • 3.6. Pure licensing agreement structure
    • 3.6.1. Example pure licensing agreements
    • 3.6.1.a. Case study 9
    • 3.6.1.b. Case study 10
  • 3.7. Multicomponent discovery stage partnering agreements
    • 3.7.1.a. Example multicomponent early stage clauses
    • 3.7.1.a. Case study 11
    • 3.7.1.b. Case study 12

Chapter 4 - Discovery stage partnering payment strategies

  • 4.1. Introduction
  • 4.2. Discovery stage payment strategies
  • 4.3. Payment options
    • 4.3.1. Headline values
    • 4.3.2. Upfront payments
    • 4.3.2.1. Conditionality of upfront payments
    • 4.3.3. Loans
    • 4.3.4. Convertible loans
    • 4.3.5. Equity
    • 4.3.6. R&D funding
    • 4.3.7. Licensing fees
    • 4.3.8. Milestone payments
    • 4.3.9. Royalty payments
    • 4.3.9.1. Issues affecting royalty rates
    • 4.3.9.2. Royalties on combination products
    • 4.3.9.2.a. Case study 13
    • 4.3.9.3. Guaranteed minimum/maximum annual payments
    • 4.3.9.4. Royalty stacking
    • 4.3.9.5. Royalties and supply/purchase contracts
    • 4.3.10. Quids
    • 4.3.11. Option payments

Chapter 5 - Trends in discovery stage deal making

  • 5.1. Introduction
  • 5.2. Discovery stage partnering over the years
    • 5.2.1. Attributes of discovery deals
  • 5.3. Discovery stage partnering by deal type
  • 5.4. Discovery stage partnering by disease type
  • 5.5. Partnering by discovery stage technology type
  • 5.6. Discovery stage partnering by most active company, 2020 to 2025

Chapter 6 - Payment terms for discovery stage partnering

  • 6.1. Introduction
  • 6.2. Guidelines for discovery stage payment terms
    • 6.2.1. Upfront payments
    • 6.2.2. Milestone payments
    • 6.2.3. Royalty payments
  • 6.3. Discovery stage payment terms - deal data analysis
    • 6.3.1. Public data
    • 6.3.2. Survey data
  • 6.4. Payment terms analysis
    • 6.4.1. Discovery stage headline values
    • 6.4.2. Discovery stage deal upfront payments
    • 6.4.3. Discovery stage deal milestone payments
    • 6.4.4. Discovery stage royalty rates

Chapter 7 - Leading discovery stage deals

  • 7.1. Introduction
  • 7.2. Top discovery stage deals by value

Chapter 8 - Top 25 most active discovery stage dealmakers

  • 8.1. Introduction
  • 8.2. Top 25 most active discovery stage dealmakers

Chapter 9 - Discovery stage partnering contracts directory

  • 9.1. Introduction
  • 9.2. Discovery stage deals with contracts 2020 to 2025

Chapter 10 - Discovery stage deal making by development stage

  • 10.1. Introduction
  • 10.2. Deals by discovery stage

Appendices

  • Appendix 1 - Discovery stage dealmaking by companies A-Z
  • Appendix 2 - Discovery stage dealmaking by industry sector
  • Appendix 3 - Discovery stage dealmaking by stage of development
  • Appendix 4 - Discovery stage dealmaking by therapy area
  • Appendix 5 - Discovery stage dealmaking by technology type
  • About Biopharma Research Ltd
  • Current Partnering
  • Current Agreements
  • Recent report titles from Current Partnering

Table of figures

  • Figure 1: Definition of discovery, preclinical and clinical phases in dealmaking
  • Figure 3: Components of the pure licensing deal structure
  • Figure 4: Payment options for discovery stage partnering deals
  • Figure 5: Issues affecting royalty rates
  • Figure 6: Discovery stage partnering frequency 2020 - 2025
  • Figure 7: Discovery stage partnering by deal type since 2020
  • Figure 8: Discovery stage partnering by disease type since 2020
  • Figure 9: Discovery stage partnering by technology type since 2020
  • Figure 10: Top 25 most active discovery stage dealmakers, 2020 to 2025
  • Figure 11: Review of median upfront payments for discovery stage deals
  • Figure 12: Review of median milestone payments for discovery stage deals
  • Figure 13: Review of median royalty payments for discovery stage deals
  • Figure 14: Discovery stage deals with a headline value
  • Figure 15: Discovery stage deals with an upfront value
  • Figure 16: Discovery stage deals with a milestone value
  • Figure 17: Discovery stage deals with a royalty rate value
  • Figure 18: Top discovery stage deals by deal value since 2020
  • Figure 19: Most active discovery stage dealmakers 2020 to 2025