下游加工市場：按技術、按產品、按應用、按最終用戶、按地區

2024年全球下游加工市場規模預計為261.1億美元，預計2031年將達771億美元，2024年至2031年複合年成長率為16.7%。

圖 1. 2024 年下游加工市場佔有率(%)，依地區分類

下游加工是指發酵後發生的生物加工中的精製和回收步驟，以從細胞生質能或發酵液中分離出所需的活性成分或產物。這包括澄清以去除細胞碎片和成分、濃縮以減少減重並分離和回收所需產物，以及使用層析法技術的最終精製。下游加工在確保生物製藥的純度、品質和穩定性以及決定其在市場上的成功方面發揮關鍵作用。澄清和精製技術的進步，例如膨脹床層析法分離和連續處理，使得提高產品產量和吞吐量並降低產品成本成為可能。

市場動態：

生物製藥行業的快速成長、生技藥品優於小分子藥物的偏好以及對單株抗體和疫苗的強勁需求推動了下游加工市場的成長。然而，與下游精製設備和操作相關的高成本阻礙了他們的發展。新興市場連續製造和一次性技術的開拓為市場提供了開發整合和模組化流程創新解決方案的重大機會。市場領導正專注於合作夥伴關係和併購活動，以加強其精製解決方案和層析法樹脂的產品組合。

本研究的主要特點

• 本報告對全球下游加工市場進行了詳細分析，並提出了以2023年為基準年的預測期（2024-2031）的市場規模和年複合成長率（CAGR%）。
• 它還闡明了各個細分市場的潛在商機，並解釋了該市場中有吸引力的投資提案的矩陣。
• 它還提供了有關市場促進因素、限制因素、機會、新產品發布和核准、市場趨勢、區域前景、主要企業採取的競爭策略等的重要見解。
• 它根據公司亮點、產品系列、主要亮點、財務表現和策略等參數，介紹了全球下游加工市場的主要企業。
• 該報告的見解使負責人和公司經營團隊能夠就未來的產品發布、類型升級、市場擴張和行銷策略做出明智的決策。
• 本研究報告針對該產業的各個相關人員，如投資者、供應商、產品製造商、經銷商、新進業者和財務分析師。
• 透過用於全球下游工藝市場分析的各種策略矩陣，將促進相關人員做出決策。

目錄

第1章 研究目的與前提

• 研究目標
• 先決條件
• 簡稱

第2章 市場展望

• 報告說明
  • 市場定義和範圍
• 執行概述
• 一致的機會地圖 (COM)

第3章市場動態、法規及趨勢分析

• 市場動態
  • 促進因素
  • 抑制因素
  • 機會
• 影響分析
• 市場趨勢
• 監管場景
• 收購和合作場景
• 資金籌措和投資
• PEST分析
• 波特的分析

第4章全球下游製程市場－冠狀病毒 (COVID-19) 大流行的影響

• 整體影響
• 政府舉措
• COVID-19 對市場的影響

第5章 全球下游製程市場，依技術分類，2019-2031 年（十億美元）

• 介紹
• 淨化技術
• 固液分離
• 澄清/濃縮

第6章 全球下游加工市場（按產品），2019-2031 年（十億美元）

• 介紹
• 層析管柱和樹脂
• 篩選
• 蒸發器
• 離心機
• 其他

第7章 2019-2031 年全球下游製程市場（按應用）（十億美元）

• 介紹
• 抗體產生
• 疫苗生產
• 胰島素產生
• 其他

第 8 章 2019-2031 年全球下游製程市場（按地區）（十億美元）

• 介紹
• 拉丁美洲
• 歐洲
• 亞太地區
• 中東

第9章 競爭格局

• 公司簡介
  • Merck KGaA
  • Thermo Fisher Scientific Inc.
  • GE Healthcare
  • Sartorius Stedim Biotech SA
  • Repligen Corporation
  • Pall Corporation
  • M Company
  • Eppendorf AG
  • Agilent Technologies, Inc.
  • Waters Corporation
  • Shimadzu Corporation
  • Bio-Rad Laboratories, Inc.
  • Avantor Performance Materials, LLC
  • Tosoh Corporation
  • Column Technology Inc.
  • Purolite
  • WR Grace &Co.
  • Asahi Kasei Corporation
  • Novasep Holding SAS
  • Boehringer Ingelheim

第10章分析師建議

• 升起和降落
• 綜合機會圖

第11章 參考文獻與調查方法

• 參考
• 調查方法

The Global Downstream Processing Market is estimated to be valued at USD 26.11 Bn in 2024 and is expected to reach USD 77.10 Bn by 2031, exhibiting a compound annual growth rate (CAGR) of 16.7% from 2024 to 2031.

Figure 1. Downstream Processing Market Share (%), By Region, 2024

Downstream processing refers to the purification and recovery steps in bioprocessing undertaken after fermentation to isolate the active ingredient or product of interest from cellular biomass or fermentation broth. It involves clarification to remove cellular debris and components, concentration to separate and recover the target product by reducing volume, and final purification using chromatographic techniques. Downstream processing plays a critical role in ensuring the purity, quality, and stability of biopharmaceutical products, thereby determining their success in the market. Advances in technologies for clarification and purification such as expanded bed chromatographic separation and continuous processing have enabled higher product yields and throughput at reduced costs of goods.

Market Dynamics:

The downstream processing market growth is driven by the rapid growth of the biopharmaceutical industry, preference for biologics over small molecule drugs, and strong demand for monoclonal antibodies and vaccines. However, high costs associated with downstream purification equipment and operations acts as a restraint. Advancements in continuous manufacturing and single-use technologies provide significant opportunities for market players to develop innovative solutions for integrated and modular processes. Market leaders are focusing on partnerships and M&A activities to strengthen their portfolio of purification solutions and chromatography resins.

Key features of the study:

• This report provides in-depth analysis of the global downstream processing market, and provides market size (USD Million) and compound annual growth rate (CAGR%) for the forecast period (2024-2031), considering 2023 as the base year
• It elucidates potential revenue opportunities across different segments and explains attractive investment proposition matrices for this market
• This study also provides key insights about market drivers, restraints, opportunities, new product launches or approval, market trends, regional outlook, and competitive strategies adopted by key players
• It profiles key players in the global downstream processing market based on the following parameters - company highlights, products portfolio, key highlights, financial performance, and strategies
• Key companies covered as a part of this study include GE Healthcare, Merck KGaA, Thermo Fisher Scientific Inc., 3M Company, Lonza Group AG, Eppendorf AG
• Insights from this report would allow marketers and the management authorities of the companies to make informed decisions regarding their future product launches, type up-gradation, market expansion, and marketing tactics
• The global downstream processing market report caters to various stakeholders in this industry including investors, suppliers, product manufacturers, distributors, new entrants, and financial analysts
• Stakeholders would have ease in decision-making through various strategy matrices used in analyzing the global downstream processing market

Detailed Segmentation-

• By Technique
  • Purification Techniques
  • Solid-Liquid Separation
  • Clarification/Concentration
• By Product
  • Chromatography Columns and Resins
  • Filters
  • Evaporators
  • Centrifuges
  • Other Products
• By Application
  • Antibodies Production
  • Vaccines Production
  • Insulin Production
  • Other Application
• By End User
  • Biopharmaceutical Companies
  • CMOs/CDMOs
  • Research Institutes
  • CROs
  • Others
• By Region:
  • North America
  • Europe
  • Asia Pacific
  • Latin America
  • Middle East
  • Africa
• Company Profiles:
  • Merck KGaA
  • Thermo Fisher Scientific Inc.
  • GE Healthcare
  • Sartorius Stedim Biotech S.A.
  • Repligen Corporation
  • Pall Corporation
  • M Company
  • Eppendorf AG
  • Agilent Technologies, Inc.
  • Waters Corporation
  • Shimadzu Corporation
  • Bio-Rad Laboratories, Inc.
  • Avantor Performance Materials, LLC
  • Tosoh Corporation
  • Column Technology Inc.
  • Purolite
  • R. Grace & Co.
  • Asahi Kasei Corporation
  • Novasep Holding S.A.S
  • Boehringer Ingelheim

Table of Contents

1. Research Objectives and Assumptions

• Research Objectives
• Assumptions
• Abbreviations

2. Market Purview

• Report Description
  • Market Definition and Scope
• Executive Summary
  • Market Snapshot, By Technique
  • Market Snapshot, By Product
  • Market Snapshot, By Application
  • Market Snapshot, By End User
  • Market Snapshot, By Region
• Coherent Opportunity Map (COM)

3. Market Dynamics, Regulations, and Trends Analysis

• Market Dynamics
  • Drivers
  • Restraints
  • Opportunities
• Impact Analysis
• Market Trends
• Key Developments
• Regulatory Scenario
• Acquisitions and Partnerships Scenario
• Funding and Investments
• PEST Analysis
• Porter's Analysis

4. Global Downstream Processing Market - Impact of Coronavirus (COVID-19) Pandemic

• Overall Impact
• Government Initiatives
• COVID-19 Impact on the Market

5. Global Downstream Processing Market, By Technique, 2019 - 2031, (USD Bn)

• Overview
  • Market Share Analysis, 2024 and 2031 (%)
  • Y-o-Y Growth Analysis, 2020 - 2031
  • Segment Trends
• Purification Techniques
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Solid-Liquid Separation
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Clarification/Concentration
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)

6. Global Downstream Processing Market, By Product, 2019 - 2031, (USD Bn)

• Overview
  • Market Share Analysis, 2024 and 2031 (%)
  • Y-o-Y Growth Analysis, 2020 - 2031
  • Segment Trends
• Chromatography Columns and Resins
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Filters
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Evaporators
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Centrifuges
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Others
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)

7. Global Downstream Processing Market, By Application, 2019 - 2031, (USD Bn)

• Overview
  • Market Share Analysis, 2024 and 2031 (%)
  • Y-o-Y Growth Analysis, 2020 - 2031
  • Segment Trends
• Antibodies Production
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Vaccines Production
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Insulin Production
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)
• Other Applications
  • Overview
  • Market Size and Forecast, and Y-o-Y Growth, 2019-2031, (USD Bn)

8. Global Downstream Processing Market, By Region, 2019 - 2031, (USD Bn)

• Introduction
  • Market Share Analysis, By Region, 2024 and 2031 (%)
  • Y-o-Y Growth Analysis, For Region, 2020-2031
  • Regional Trends
    • North America
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • U.S.
    • Canada
• Latin America
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • Brazil
    • Mexico
    • Argentina
    • Rest of Latin America
• Europe
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • U.K.
    • Germany
    • Italy
    • France
    • Spain
    • Russia
    • Rest of Europe
• Asia Pacific
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • China
    • India
    • Japan
    • ASEAN
    • Australia
    • South Korea
    • Rest of Asia Pacific
• Middle East
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country, 2019 - 2031, (USD Bn)
    • GCC
    • Israel
    • Rest of Middle East
    • Africa
  • Introduction
  • Market Size and Forecast, and Y-o-Y Growth, By Technique, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Product, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Application, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By End User, 2019 - 2031, (USD Bn)
  • Market Size and Forecast, and Y-o-Y Growth, By Country/Region, 2019 - 2031, (USD Bn)
    • North Africa
    • Central Africa
    • South Africa

9. Competitive Landscape

• Company Profiles
  • Merck KGaA
    • Company Highlights
    • Product Portfolio
    • Key Highlights
    • Financial Performance
    • Market Strategies
  • Thermo Fisher Scientific Inc.
  • GE Healthcare
  • Sartorius Stedim Biotech S.A.
  • Repligen Corporation
  • Pall Corporation
  • M Company
  • Eppendorf AG
  • Agilent Technologies, Inc.
  • Waters Corporation
  • Shimadzu Corporation
  • Bio-Rad Laboratories, Inc.
  • Avantor Performance Materials, LLC
  • Tosoh Corporation
  • Column Technology Inc.
  • Purolite
  • W.R. Grace & Co.
  • Asahi Kasei Corporation
  • Novasep Holding S.A.S
  • Boehringer Ingelheim

10. Analyst Recommendations

• Wheel of Fortune
• Analyst View
• Coherent Opportunity Map

11. References and Research Methodology

• References
• Research Methodology
• About us and Sales Contact