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市場調查報告書
商品編碼
1519769
2024-2032 年囊性纖維化治療市場報告(依藥物類別、藥物分子類型、給藥途徑、最終使用者和地區)Cystic Fibrosis Therapeutics Market Report by Drug Class, Drug Molecule Type, Route of Administration, End-User, and Region 2024-2032 |
IMARC Group年,全球囊性纖維化治療市場規模達到 72 億美元。囊性纖維化盛行率不斷上升,個人對基於遺傳因素的個人化治療方法的偏好不斷增加,以及基因療法最新進展的廣泛利用是推動市場成長的一些主要因素。
囊性纖維化治療可以控制影響呼吸和消化系統的遺傳性疾病的症狀。它涵蓋一系列藥物,包括 CFTR 調節劑和基因療法,提供量身定做的治療方案。它透過增強 CFTR 蛋白的功能來幫助糾正導致 CF 的潛在遺傳缺陷。它透過控制症狀和減緩疾病進展來提高生活品質。它可以增強肺功能,幫助 CF 患者更輕鬆地呼吸並減輕呼吸道症狀。
個人對基於遺傳因素的個人化治療方法的日益偏好正在加強市場的成長。除此之外,各國政府紛紛推出針對CF研究和治療開發的政策和資金,這為CF的研究和治療開發提供了良好的市場前景。此外,對孤兒藥開發的監管激勵措施不斷加強,正在鼓勵製藥公司投資 CF 療法。此外,製藥公司、研究機構和醫療保健提供者之間不斷加強的合作正在加速新療法的開發。此外,穿戴式裝置和遠距醫療等技術的廣泛使用正在增強患者監測和治療服務。
CFTR 調變器的進步
CFTR調節藥物的開發和持續改進是促進市場成長的主要因素之一。這些藥物直接針對有缺陷的 CFTR 蛋白,這是 CF 患者產生濃稠黏液和隨後出現健康併發症的原因。除此之外,製藥公司不斷投資於研發 (R&D) 活動,以推出新一代 CFTR 調節劑,以提供更高的有效性和更廣泛的適用性。這些進步提供了更全面的解決方案並改善了個人的整體福祉。它們還支持改善特定 CF 患者群體的黏液清除、減少呼吸道症狀和增強肺功能。
基因療法的發展
基因療法的發展是促進市場成長的另一個主要因素。這些創新療法透過將有缺陷的 CFTR 基因的功能性拷貝引入受影響的細胞中,幫助解決 CF 的根本原因,並促進 CF 的治癒或長期管理。此外,基因療法最新進展的使用不斷增加,例如 Kaftrio 和 Trikafta 等基於基因的治療方法已被批准用於治療 CF 症狀,這提供了良好的市場前景。除此之外,基因療法的發展正在加強市場的成長。這些療法有助於提供更有效和更有針對性的治療,擴大治療選擇,並促進對潛在治療方法的研究。
增加盛行率和早期診斷
由於多種因素,CF 盛行率不斷上升,特別是在千禧世代人群中,正在推動對治療藥物的需求。同時,診斷能力的提高正在創造積極的市場前景。此外,醫療保健系統越來越擅長透過新生兒篩檢計劃和基因檢測來識別 CF 病例。除此之外,早期診斷可以在更年輕的時候開始治療,這可以顯著影響疾病進展並改善長期結果。此外,基因檢測和新生兒篩檢計畫的持續進步使得嬰幼兒 CF 的診斷變得更快、更可靠。
The global cystic fibrosis therapeutics market size reached US$ 7.2 Billion in 2023. Looking forward, IMARC Group expects the market to reach US$ 14.7 Billion by 2032, exhibiting a growth rate (CAGR) of 7.9% during 2024-2032. The rising prevalence of cystic fibrosis, increasing preferences of individuals for personalized treatment approaches based on genetic factors, and the widespread utilization of recent advancements in gene therapy are some of the major factors propelling the market growth.
Cystic fibrosis therapeutics enables management of the symptoms of a genetic disease affecting the respiratory and digestive systems. It encompasses a range of drugs, including CFTR modulators and gene therapy, offering tailored treatment options. It helps correct the underlying genetic defect responsible for CF by enhancing the function of the CFTR protein. It contributes to a better quality of life by managing symptoms and slowing disease progression. It can enhance lung function, helping individuals with CF breathe more easily and reducing respiratory symptoms.
Rising preferences of individuals for personalized treatment approaches based on genetic factors is strengthening the growth of the market. Apart from this, governing authorities of various countries are introducing policies and funding for CF research and treatment development, which is offering a favorable market outlook. Additionally, a continuous rise in regulatory incentives for orphan drug development is encouraging pharmaceutical companies to invest in CF therapeutics. Moreover, the rising collaborative efforts between pharmaceutical companies, research institutions, and healthcare providers are accelerating the development of new therapies. Furthermore, the widespread use of technology, such as wearable devices and telemedicine, is enhancing patient monitoring and treatment delivery.
Advancements in CFTR modulators
The development and continued improvement of CFTR modulator drugs represent one of the primary factors contributing to the market growth. These medications directly target the defective CFTR protein, which is responsible for the thick mucus production and subsequent health complications in individuals with CF. Apart from this, pharmaceutical companies are continuously investing in research and development (R&D) activities to introduce new generations of CFTR modulators that offer greater effectiveness and broader applicability. These advancements provide more comprehensive solutions and improve the overall well-being of individuals. They also support improved mucus clearance, reduced respiratory symptoms, and enhanced lung function in specific CF patient populations.
Development of gene-based therapies
The development of gene-based therapies is another major factor facilitating the market growth. These innovative treatments help address the root cause of CF by introducing functional copies of the defective CFTR gene into affected cells and facilitating a cure or long-term management of CF. Additionally, the rising utilization of recent advancements in gene therapy, such as the approval of gene-based treatments like Kaftrio and Trikafta for treating CF symptoms is offering a favorable market outlook. Apart from this, the evolution of gene-based therapies is strengthening the growth of the market. These therapies aid in providing more effective and targeted treatments, expanding treatment options, and fostering research into potential curative approaches.
Increasing prevalence and early diagnosis
The rising prevalence of CF, especially among the millennial population due to several factors, is driving the demand for therapeutics. Along with this, improved diagnostic capabilities are creating a positive market outlook. Additionally, healthcare systems are becoming more adept at identifying CF cases through newborn screening programs and genetic testing. Apart from this, early diagnosis allows for the initiation of treatment at a younger age, which can significantly impact disease progression and improve long-term outcomes. Furthermore, ongoing advancements in genetic testing and newborn screening programs are allowing for quicker and more reliable diagnosis of CF in infants and young children.
IMARC Group provides an analysis of the key trends in each segment of the market report, along with forecasts at the global, regional, and country levels from 2024-2032. Our report has categorized the market based on drug class, drug molecule type, route of administration, and end-user.
Pancreatic Enzyme Supplements
Mucolytics
Bronchodilators
CFTR Modulators
Antibiotics
Others
CFTR modulators hold the largest market share
A detailed breakup and analysis of the market based on the drug class has also been provided in the report. This includes pancreatic enzyme supplements, mucolytics, bronchodilators, CFTR modulators, antibiotics, and others. According to the report, CFTR modulators accounted for the largest market share as they offer a highly targeted treatment approach. They address the root cause of CF at the molecular level, focusing on the defective CFTR protein. They work by improving the function of the defective CFTR protein and regulate the flow of salt and fluids in and out of cells. Additionally, the expanded approval for use in various CF patient populations, including those with specific genetic mutations drives its demand across the globe. Apart from this, pharmaceutical companies continue to invest heavily in research activities to create new generations of CFTR modulators. These efforts aim to improve the effectiveness of existing drugs and develop new ones, ensuring a competitive edge in the market.
Small Molecule Drugs
Biologics
Small molecule drugs account for the majority of the market share
The report has provided a detailed breakup and analysis of the market based on the drug molecule type. This includes small molecule drugs and biologics. According to the report, small molecule drugs represented the largest segment as they have excellent bioavailability and get efficiently absorbed into the bloodstream after oral administration. This ensures that a significant portion of the drug reaches its target site, enhancing therapeutic efficacy. Apart from this, they are generally cost-effective to manufacture, making them attractive to pharmaceutical companies. The production processes for these drugs are well-established, allowing for economies of scale and efficient mass production. Moreover, regulatory agencies, such as the U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA), have established clear guidelines for the development and approval of small molecule drugs. This regulatory support ensures their safety, quality, and efficacy, bolstering confidence among healthcare professionals and patients.
Oral Drugs
Inhaled Drugs
Oral drugs dominate the market
A detailed breakup and analysis of the market based on the route of administration has also been provided in the report. This includes oral drugs and inhaled drugs. According to the report, oral drugs accounted for the largest market share as they are often more cost-effective than other forms of medication delivery. They require less infrastructure for administration and reduce the need for healthcare professionals' involvement, leading to lower overall healthcare costs. Additionally, they do not involve needles or invasive procedures, making them more tolerable for a broader patient population. Apart from this, they are usually administered in the form of tablets or capsules, offering a level of accessibility and convenience. Apart from this, patients can take these medications easily without the need for specialized medical personnel or equipment. This convenience supports long-term treatments, chronic conditions, and self-administered therapies for several chronic diseases.
Hospitals
Clinics
Others
Hospitals dominate the market
The report has provided a detailed breakup and analysis of the market based on the end-user. This includes hospitals, clinics, and others. According to the report, hospitals represented the largest segment as they provide comprehensive healthcare services under one roof. They offer a wide range of medical specialties, including emergency care, surgery, radiology, pathology, and specialized clinics. Apart from this, they are primarily associated with acute care, which involves the treatment of severe and life-threatening conditions. Moreover, they are equipped with state-of-the-art medical equipment and technology. This includes advanced diagnostic tools, imaging systems, surgical robots, and intensive care units. These resources enable hospitals to deliver cutting-edge medical treatments and procedures. Furthermore, many hospitals are affiliated with medical schools and research institutions, fostering an environment of continuous learning and innovation. This research-driven approach leads to the development of new medical treatments, therapies, and best practices.
North America
United States
Canada
Asia Pacific
China
Japan
India
South Korea
Australia
Indonesia
Others
Europe
Germany
France
United Kingdom
Italy
Spain
Russia
Others
Latin America
Brazil
Mexico
Others
Middle East and Africa
Europe leads the market, accounting for the largest cystic fibrosis therapeutics market share
The market research report has also provided a comprehensive analysis of all the major regional markets, which include North America (the United States and Canada); Asia Pacific (China, Japan, India, South Korea, Australia, Indonesia, and others); Europe (Germany, France, the United Kingdom, Italy, Spain, Russia, and others); Latin America (Brazil, Mexico, and others); and the Middle East and Africa. According to the report, Europe accounted for the largest market share since the region has a well-developed healthcare infrastructure with widespread access to medical facilities and specialized CF centers. Additionally, Europe has a relatively high prevalence of CF. This increased prevalence drives research and development (R&D) efforts as well as market demand for CF therapeutics. Apart from this, Europe is home to some of the largest pharmaceutical companies in the world. These companies invest heavily in CF therapeutics, leading to the development of innovative treatments. Furthermore, the European Medicines Agency (EMA) provides a clear regulatory pathway for the approval of CF drugs. Moreover, many European governments allocate substantial funding to support CF research and treatment. This funding accelerates the development of new therapies and promotes market growth.
Companies are investing heavily in research and development (R&D) activities to discover new treatments and medications that target the underlying causes of cystic fibrosis. Additionally, they are working on therapies tailored to specific genetic mutations associated with cystic fibrosis. This ensures a more effective and targeted approach to treatment. Apart from this, many companies are forming partnerships with academic institutions, research organizations, and other pharma companies to accelerate drug development and bring new therapies to market more quickly. Furthermore, they are continuously conducting and investing in phase I, II, and III clinical trials to test the efficacy and safety of new cystic fibrosis therapies.
AbbVie Inc.
Alaxia
Alcresta Therapeutics Inc.
Allergan
AstraZeneca
F. Hoffmann-La Roche Ltd.
Gilead Sciences Inc.
Merck & Co. Inc.
Novartis AG
Teva Pharmaceutical Industries Ltd.
Vertex Pharmaceuticals Inc.
(Please note that this is only a partial list of the key players, and the complete list is provided in the report.)
In December 2022, Vertex Pharmaceuticals Inc. announced that the U.S. Food and Drug Administration cleared its Investigational New Drug (IND) application for VX-522, a messenger ribonucleic acid (mRNA) therapy targeted at treating the underlying cause of cystic fibrosis (CF) lung disease.
In October 2020, AbbVie Inc. announced the partnership with Roche and the acquisition of the TMEM16A potentiators portfolio. The relationship influenced the expansion of the company's product line.