![]() |
市場調查報告書
商品編碼
1383350
囊腫纖維化市場至2030年預測:按藥物類別、治療方法、給藥途徑、配銷通路和地區進行的全球分析Cystic Fibrosis Market Forecasts to 2030 - Global Analysis By Drug Class, Treatment Method, Route of Administration, Distribution Channel and By Geography |
根據 Stratistics MRC 的資料,2023年全球囊腫纖維化市場規模為 114.9 億美元,預計在預測期內年複合成長率為 22.4%,到2030年將達到 473 億美元。
基因突變是導致囊腫纖維化(CF)遺傳疾病的原因。特定體液的蛋白質分泌受基因控制。這會影響身體的各個器官,並導致黏液和汗水變稠。此外,這種疾病會改變電解質輸送系統,導致細胞吸收鈉和水,進而導致負責分泌汗水和黏液的腺體出現問題。
根據囊腫纖維化患者登記處的資料,目前美國有超過 30,000 人患有這種疾病,估計全球約有 70,000 人患有這種疾病。
基因序列測定技術和基因檢測的進步使得準確識別個別患者的 CFTR 基因突變成為可能。借助這種個體化方法,醫療專業人員可以根據每位患者的特定基因譜量身定做治療計劃並提供最合適的藥物。此外,對個人化醫療的重視可以提高病患滿意度和治療效果,進一步激發市場活力。
囊腫纖維化的治療費用非常昂貴,尤其是 CFTR 調節劑,每年可達數十萬美元。此類過度支出可能會讓保險公司和衛生系統不堪重負,難以為所有患者提供服務。此外,對這些療法的長期負擔能力的擔憂也可能是由成本驅動的,影響市場擴張。
智慧型的進步改善治療管理。然而,這些實用且高效的給藥策略可確保患者獲得治療的全部益處,改善患者體驗,促進醫囑遵從性,最終有助於擴大市場。
囊腫纖維化治療計劃通常包括藥物、治療方法和生活方式改變之間的複雜相互作用。這種複雜性可能會讓患者不知所措並降低治療的醫囑遵從性。此外,違規可能會導致醫療費用增加和更頻繁的病情惡化。
COVID-19大流行也對患者治療、臨床試驗和醫療保健系統造成重大干擾,影響了囊腫纖維化市場。這場大流行導致醫療資源緊張,減緩了新治療方法的推出,並推遲了研究和開發。被診斷出患有囊腫纖維化的人被認為是高風險族群,經常面臨更大的健康風險和獲得必要醫療照護的機會有限。此外,大流行的經濟影響增加了醫療保健系統和患者的經濟負擔,可能會影響囊腫纖維化治療的成本和可用性。
跨膜傳導調節劑調節劑預計將為這種複雜且具有挑戰性的遺傳疾病的治療帶來範式轉變,並且由於其變革性影響,預計將佔據囊腫纖維化市場的最大佔有率。此外,跨膜傳導調節劑(例如 Trikafta)已經改變了囊腫纖維化的治療方法。這些藥物透過解決導致囊腫纖維化的潛在遺傳缺陷來改善黏液清除和氯離子轉運。對於許多患有某些基因突變的患者來說,跨膜傳導調節劑可顯著改善肺功能,減少病情惡化,並改善生活品質。
在囊腫纖維化市場中,吸入療法領域的年複合成長率最高。近年來,吸入療法變得越來越普及,因為它能夠以有針對性且有效的方式將藥物直接給藥到肺部。吸入器通常用於囊性纖維化治療,以輸送藥物來幫助控制囊腫纖維化的症狀。此外,吸入劑領域的顯著成長歸因於多種因素,例如吸入技術的進步、對吸入療法益處的認知不斷提高以及專門用於吸入給藥的新藥物的開發。
囊腫纖維化在北美擁有最大的市場佔有率。這是由於支持該地區市場主導地位的幾個因素。首先,在北美,無論是一般民眾或醫療相關人員對囊腫纖維化的認知度都很高,醫療基礎設施也很發達。這將有利於患者的早期診斷和治療,擴大患者基礎,並擴大囊腫纖維化治療藥物市場。此外,該地區擁有許多製藥公司和研究機構,積極致力於開發尖端的囊腫纖維化治療方法。最先進的醫療設備和優惠的醫療償付政策也推動了該地區的市場佔有率。
預計亞太地區囊腫纖維化市場的年複合成長率最高。該地區囊腫纖維化患者的數量不斷增加,包括醫療保健在內的許多行業經歷快速成長。該地區的快速成長歸因於許多因素,包括公眾對囊腫纖維化的認知不斷提高、醫療基礎設施的改善以及醫療費用的上升。此外,中國和印度等政府實施目的是使醫療保健更加負擔得起和更容易獲得的計劃,提供更好的診斷和治療選擇,以幫助囊腫纖維化患者受益。
According to Stratistics MRC, the Global Cystic Fibrosis Market is accounted for $11.49 billion in 2023 and is expected to reach $47.30 billion by 2030 growing at a CAGR of 22.4% during the forecast period. A genetic mutation is the cause of the inherited disease known as cystic fibrosis (CF). Certain bodily liquids' protein secretion is regulated by genes. This affects different organs in the body, which tends to thicken mucus and sweat. Moreover, this illness modifies the electrolyte transport system, which results in the absorption of sodium and water by cells and causes issues with the glands responsible for producing sweat and mucus.
According to the Cystic Fibrosis Patient Registry, it is estimated that more than 30,000 people are currently suffering from this condition in the U.S. and it is estimated that about 70,000 people are suffering from it across the globe.
The ability to precisely identify CFTR gene mutations in individual patients has been made possible by advances in genetic sequencing technologies and genetic testing. With the help of this individualized approach, medical professionals can customize treatment plans and offer the best medications depending on each patient's particular genetic profile. Additionally, the market is further propelled by the emphasis on personalized medicine, which raises patient satisfaction and treatment effectiveness.
The cost of treating cystic fibrosis can be extremely high, sometimes amounting to hundreds of thousands of dollars per year, particularly for CFTR modulators. These excessive expenses may put pressure on insurers and healthcare systems, making it more difficult to provide access to all patients. Furthermore, concerns about these treatments' long-term affordability are also brought up by cost, which could have an impact on market expansion.
Treatment administration has been enhanced by advances in drug delivery, such as intelligent inhalers and effective nebulizers. However, since they guarantee that patients get the full benefit of their treatments, these practical and efficient drug delivery strategies improve patient experience, promote adherence, and subsequently aid in market expansion.
Treatment plans for cystic fibrosis frequently entail a complicated mix of drugs, therapies, and lifestyle modifications. This complexity has the potential to overwhelm patients and result in poor adherence to treatment, which will ultimately compromise the efficacy of therapies and patient outcomes. Moreover, healthcare expenses may rise, and exacerbations may occur more frequently as a result of noncompliance.
The COVID-19 pandemic caused major disruptions in patient care, clinical trials, and healthcare systems, which in turn affected the cystic fibrosis market. The pandemic put a strain on healthcare resources, delayed the introduction of new treatments, and postponed research and development. Individuals diagnosed with cystic fibrosis, who were regarded as a high-risk population, experienced increased health risks and frequently had limited access to necessary medical care. Furthermore, the pandemic's economic effects put more strain on healthcare systems and patients' finances, which might have an impact on the cost and accessibility of cystic fibrosis treatments.
CFTR modulators are expected to hold the largest share in the cystic fibrosis market due to their transformative impact, which is expected to represent a paradigm shift in the treatment of this complex and challenging genetic disease. Moreover, treatment for cystic fibrosis has been transformed by CFTR modulators such as Trikafta. These medications improve mucus clearance and chloride transport by addressing the underlying genetic defect that causes cystic fibrosis. For many patients with particular genetic mutations, CFTR modulators greatly improve lung function, lower exacerbations, and improve quality of life.
The inhaled segment of the cystic fibrosis market has the highest CAGR. Because inhaled therapies deliver medication directly to the lungs in a targeted and effective manner, they have become increasingly popular in recent years. Inhalers are commonly used in these therapies to deliver medications that assist in controlling the symptoms of cystic fibrosis. Additionally, the significant growth of the inhaled segment can be attributed to various factors, such as the progression of inhalation technology, heightened consciousness regarding the advantages of inhalation treatments, and the creation of novel medications especially intended for inhalation administration.
North America holds the largest market share for cystic fibrosis. This is explained by a number of factors that support the region's market dominance. First off, both the general public and medical professionals in North America are highly aware of cystic fibrosis, and the continent has a well-established healthcare infrastructure. This makes it easier to diagnose and treat patients early, which expands the patient pool and raises the market for cystic fibrosis treatments. Furthermore, there are many pharmaceutical companies and research facilities in the area that are actively working to develop cutting-edge cystic fibrosis treatments. The availability of cutting-edge medical equipment and advantageous reimbursement practices also boost the market share of the area.
The Asia-Pacific region is anticipated to have the highest CAGR in the cystic fibrosis market. This region is seeing a rise in the number of cases of cystic fibrosis and is seeing rapid growth in a number of industries, including healthcare. The region's rapid growth is attributed to a number of factors, including expanding public awareness of cystic fibrosis, enhancing healthcare infrastructure, and rising healthcare costs. Moreover, governments in nations such as China and India are implementing programs aimed at improving healthcare affordability and accessibility, which will benefit patients with cystic fibrosis by providing better options for diagnosis and treatment.
Some of the key players in Cystic Fibrosis market include: Pharmaxis Ltd , Gilead Sciences, Inc., Teva Pharmaceuticals, Genentech Inc , AbbVie Inc., Mylan N.V, Viatris Inc., Novartis AG, Allergan PLC, Pfizer Inc, Nestle Health Science, Hoffmann-La Roche AG , BayerAG, Vertex Pharmaceuticals Incorporated, AstraZeneca , Chiesi Farmaceutici SpA and Horizon Therapeutic Plc.
In October 2023, Teva Pharmaceuticals and Sanofi have announced an agreement to jointly develop and commercialise a treatment for inflammatory bowel disease, with the deal potentially worth up to $1.5bn.The candidate, Teva's TEV'574, is an anti-TL1A therapy currently being evaluated in phase 2b clinical trials as a treatment for ulcerative colitis and Crohn's disease, the two main types of inflammatory bowel disease.
In October 2023, Viatris Inc., a global healthcare company, today announced it has received an offer for the divestiture of substantially all of its Over-the-Counter (OTC) business, and has entered into definitive agreements to divest its Women's Healthcare business, its Active Pharmaceutical Ingredients (API) business in India and commercialization rights in certain non-core markets that were acquired as part of the Upjohn Transaction.
In September 2023, PeptiDream Inc., a public Kanagawa, Japan-based biopharmaceutical today announced a new multi-target collaboration and license agreement with U.S.-based Genentech, a member of the Roche Group, focused on the discovery and development of novel macrocyclic peptide-radioisotope ("peptide-RI") drug conjugates.