下游加工市場規模、佔有率和成長分析（按技術、產品、應用、最終用戶和地區）- 2025-2032 年產業預測

2023 年下游加工市場規模價值 364 億美元，預計將從 2024 年的 423.7 億美元成長到 2032 年的 1,427.8 億美元，預測期內（2025-2032 年）的複合年成長率為 16.4%。

受生物製藥和生物技術產品需求不斷成長的推動，全球下游加工市場預計將經歷顯著成長。隨著越來越多的公司尋求生物製藥的高效精製和生產技術，下游加工技術變得至關重要。默克與無錫國家高新技術產業開發區達成的合作，體現了該產業對拓展能力的決心。然而，設備成本高、初始投資大等挑戰可能會阻礙企業成長，尤其是對中小型企業而言。層析法和過濾的進步正在提高效率和擴充性，而向一次性技術的轉變則簡化了流程、最大限度地降低了污染風險並加快了生產時間。隨著生物製藥產業的持續成長，顛覆性的市場格局預計將推動對創新解決方案的需求激增。

目錄

介紹

• 調查目的
• 研究範圍
• 定義

調查方法

• 資訊採購
• 次要和主要資料方法
• 市場規模預測
• 市場假設與限制

執行摘要

• 全球市場展望
• 供需趨勢分析
• 細分機會分析

市場動態及展望

• 市場概況
• 市場規模
• 市場動態
  • 促進因素和機會
  • 限制與挑戰
• 波特的分析

主要市場考察

• 關鍵成功因素
• 競爭程度
• 主要投資機會
• 市場生態系統
• 市場吸引力指數（2024 年）
• PESTEL 分析
• 總體經濟指標
• 價值鏈分析
• 定價分析

下游加工市場規模（依技術及複合年成長率） (2025-2032)

• 市場概況
• 精製
• 固液分離
• 澄清/濃縮

下游加工市場規模（按產品和複合年成長率） (2025-2032)

• 市場概況
• 層析管柱和樹脂
• 篩選器
• 膜吸附裝置
• 免洗用品
• 其他產品
  • 耗材和
  • 配件

下游加工市場規模（按應用和複合年成長率） (2025-2032)

• 市場概況
• 單株抗體生產
• 疫苗生產
• 胰島素生成
• 免疫球蛋白的產生
• 促紅血球生成素的產生
• 其他用途
  • 干擾素
  • 融合蛋白
  • 生長激素
  • 凝血因子
  • 抗凝血劑
  • 醫用酶
  • 抗菌
  • 抗生素
  • 集落刺激因子

下游加工市場規模（按最終用戶和複合年成長率） (2025-2032)

• 市場概況
• 生物製藥製造商
• 契約製造組織（CMO）

下游加工市場規模（按地區）及複合年成長率（2025-2032）

• 北美洲
  • 美國
  • 加拿大
• 歐洲
  • 德國
  • 西班牙
  • 法國
  • 英國
  • 義大利
  • 其他歐洲國家地區
• 亞太地區
  • 中國
  • 印度
  • 日本
  • 韓國
  • 其他亞太地區
• 拉丁美洲
  • 巴西
  • 其他拉丁美洲國家
• 中東和非洲
  • 海灣合作理事會國家
  • 南非
  • 其他中東和非洲地區

競爭資訊

• 前 5 家公司對比
• 主要企業市場定位（2024年）
• 主要市場參與者所採用的策略
• 近期市場趨勢
• 公司市場佔有率分析（2024 年）
• 主要企業簡介
  • 公司詳細資訊
  • 產品系列分析
  • 公司分部佔有率分析
  • 收益與前一年同期比較對比（2022-2024 年）

主要企業簡介

• Thermo Fisher Scientific Inc.（US）
• Merck KGaA（MilliporeSigma）（Germany）
• Danaher Corporation（Cytiva）（US）
• Sartorius Stedim Biotech SA（France）
• Lonza Group AG（Switzerland）
• 3M Company（US）
• Boehringer Ingelheim International GmbH（Germany）
• Eppendorf AG（Germany）
• Repligen Corporation（US）
• GE Healthcare（US）
• Corning Incorporated（US）
• Dover Corporation（US）
• Asahi Kasei（Japan）
• Pall Corporation（US）
• Bio-Rad Laboratories, Inc.（US）
• Agilent Technologies Inc.（US）
• Finesse Solutions, Inc.（US）
• Novasep（France）
• Rentschler Biopharma（Germany）
• Vetter Pharma International GmbH（Germany）

結論和建議

Downstream Processing Market size was valued at USD 36.4 billion in 2023 and is poised to grow from USD 42.37 billion in 2024 to USD 142.78 billion by 2032, growing at a CAGR of 16.4% during the forecast period (2025-2032).

The Global Downstream Processing Market is set for significant growth driven by the rising demand for biopharmaceuticals and biotechnology products. As companies increasingly seek efficient purification and production techniques for biotherapeutics, downstream processing technologies become essential. Collaborations like Merck's agreement with Wuxi National High-tech Industrial Development Zone illustrate the industry's commitment to expanding capabilities. However, challenges such as high equipment costs and substantial initial investments may hinder growth, particularly for smaller firms. Advancements in chromatography and filtration are improving efficiency and scalability, while the shift toward single-use technologies is streamlining processes, minimizing contamination risks, and accelerating production timelines. As the biopharmaceutical sector continues to thrive, the demand for innovative downstream processing solutions will likely surge, promising a dynamic market landscape.

Top-down and bottom-up approaches were used to estimate and validate the size of the Downstream Processing market and to estimate the size of various other dependent submarkets. The research methodology used to estimate the market size includes the following details: The key players in the market were identified through secondary research, and their market shares in the respective regions were determined through primary and secondary research. This entire procedure includes the study of the annual and financial reports of the top market players and extensive interviews for key insights from industry leaders such as CEOs, VPs, directors, and marketing executives. All percentage shares split, and breakdowns were determined using secondary sources and verified through Primary sources. All possible parameters that affect the markets covered in this research study have been accounted for, viewed in extensive detail, verified through primary research, and analyzed to get the final quantitative and qualitative data.

Downstream Processing Market Segments Analysis

Global Downstream Processing Market is segmented by Technique, Product, Application, End User and region. Based on Technique, the market is segmented into Purification, Solid-liquid Separation and Clarification/Concentration. Based on Product, the market is segmented intoChromatographyColumns and Resins, Filters, Membrane Adsorbers, Single-use Products and Other Products. Based on Application, the market is segmented into Monoclonal Antibody Production, Vaccine Production, Insulin Production, Immunoglobulin Production, Erythropoietin Production and Other Applications. Based on End User, the market is segmented into Biopharmaceutical Manufacturers and Contract Manufacturing Organizations (CMOs). Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Driver of the Downstream Processing Market

The increasing need for biopharmaceuticals, including monoclonal antibodies, vaccines, and recombinant proteins, is driving growth in the downstream processing market. This sector is essential for the purification and isolation of these intricate biological products, which is vital for ensuring their safety and effectiveness. As the biopharmaceutical industry continues to expand, there is a corresponding surge in the demand for advanced downstream processing technologies and equipment. This trend highlights the critical role that downstream processing plays in the overall biopharmaceutical production pipeline, thereby making it a key driver for market development and innovation in the industry.

Restraints in the Downstream Processing Market

The Downstream Processing market faces various restraints due to the unique attributes of each biopharmaceutical product, including size, charge, solubility, and stability. These distinct characteristics can lead to complications such as low yields, challenging purification processes, and a heightened risk of degradation throughout purification stages. As a result, creating customized downstream processes for diverse products, while simultaneously tackling product-specific obstacles, can be quite intricate. This complexity necessitates a high level of expertise and considerable optimization efforts, ultimately making it a significant challenge for companies operating within this field to achieve efficient and effective processing solutions.

Market Trends of the Downstream Processing Market

The downstream processing market is witnessing a significant trend towards process intensification and continuous manufacturing methodologies, driven by the need for enhanced efficiency and productivity in biopharmaceutical production. Techniques such as continuous chromatography and continuous centrifugation are becoming increasingly popular, offering benefits like real-time monitoring and improved process control. These innovations facilitate the optimization of processing operations, resulting in higher yields and reduced processing times. As companies strive to shorten production timelines and minimize costs, the adoption of these advanced technologies is poised to reshape the downstream processing landscape, underscoring the industry's commitment to continuous improvement and operational excellence.

Table of Contents

Introduction

• Objectives of the Study
• Scope of the Report
• Definitions

Research Methodology

• Information Procurement
• Secondary & Primary Data Methods
• Market Size Estimation
• Market Assumptions & Limitations

Executive Summary

• Global Market Outlook
• Supply & Demand Trend Analysis
• Segmental Opportunity Analysis

Market Dynamics & Outlook

• Market Overview
• Market Size
• Market Dynamics
  • Drivers & Opportunities
  • Restraints & Challenges
• Porters Analysis
  • Competitive rivalry
  • Threat of substitute
  • Bargaining power of buyers
  • Threat of new entrants
  • Bargaining power of suppliers

Key Market Insights

• Key Success Factors
• Degree of Competition
• Top Investment Pockets
• Market Ecosystem
• Market Attractiveness Index, 2024
• PESTEL Analysis
• Macro-Economic Indicators
• Value Chain Analysis
• Pricing Analysis

Global Downstream Processing Market Size by Technique & CAGR (2025-2032)

• Market Overview
• Purification
• Solid-liquid Separation
• Clarification/Concentration

Global Downstream Processing Market Size by Product & CAGR (2025-2032)

• Market Overview
• Chromatography Columns and Resins
• Filters
• Membrane Adsorbers
• Single-use Products
• Other Products
  • Consumables an
  • Accessories

Global Downstream Processing Market Size by Application & CAGR (2025-2032)

• Market Overview
• Monoclonal Antibody Production
• Vaccine Production
• Insulin Production
• Immunoglobulin Production
• Erythropoietin Production
• Other Applications
  • Interferons
  • Fusion Proteins
  • Growth Hormones
  • Blood Coagulation Factors
  • Anticoagulants
  • Medical Enzymes
  • Anti-bacterial
  • Antibiotics
  • Colony Stimulating Factors

Global Downstream Processing Market Size by End User & CAGR (2025-2032)

• Market Overview
• Biopharmaceutical Manufacturers
• Contract Manufacturing Organizations (CMOs)

Global Downstream Processing Market Size & CAGR (2025-2032)

• North America (Technique, Product, Application, End User)
  • US
  • Canada
• Europe (Technique, Product, Application, End User)
  • Germany
  • Spain
  • France
  • UK
  • Italy
  • Rest of Europe
• Asia Pacific (Technique, Product, Application, End User)
  • China
  • India
  • Japan
  • South Korea
  • Rest of Asia-Pacific
• Latin America (Technique, Product, Application, End User)
  • Brazil
  • Rest of Latin America
• Middle East & Africa (Technique, Product, Application, End User)
  • GCC Countries
  • South Africa
  • Rest of Middle East & Africa

Competitive Intelligence

• Top 5 Player Comparison
• Market Positioning of Key Players, 2024
• Strategies Adopted by Key Market Players
• Recent Developments in the Market
• Company Market Share Analysis, 2024
• Company Profiles of All Key Players
  • Company Details
  • Product Portfolio Analysis
  • Company's Segmental Share Analysis
  • Revenue Y-O-Y Comparison (2022-2024)

Key Company Profiles

• Thermo Fisher Scientific Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Merck KGaA (MilliporeSigma) (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Danaher Corporation (Cytiva) (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Sartorius Stedim Biotech S.A. (France)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Lonza Group AG (Switzerland)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• 3M Company (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Boehringer Ingelheim International GmbH (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Eppendorf AG (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Repligen Corporation (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• GE Healthcare (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Corning Incorporated (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Dover Corporation (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Asahi Kasei (Japan)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Pall Corporation (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Bio-Rad Laboratories, Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Agilent Technologies Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Finesse Solutions, Inc. (U.S.)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Novasep (France)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Rentschler Biopharma (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments
• Vetter Pharma International GmbH (Germany)
  • Company Overview
  • Business Segment Overview
  • Financial Updates
  • Key Developments

Conclusion & Recommendations