市場調查報告書
商品編碼
1383399
到 2030 年基因編輯市場預測:按產品、技術、應用、最終用戶和地區進行的全球分析Gene Editing Market Forecasts to 2030 - Global Analysis By Product, Technology, Application, End User and By Geography |
根據 Stratistics MRC 的數據,2023 年全球基因編輯市場規模為 74.5 億美元,預計預測期內年複合成長率為 17.5%,到 2030 年將達到 230.5 億美元。
一組被稱為「基因編輯」的技術允許研究人員修改生物體的 DNA。這些技術使得改變、添加或去除基因組內特定位置的遺傳物質成為可能。基因組編輯對於人類疾病預防和治療來說是一個有吸引力的領域。更複雜的疾病,如癌症、心臟病、精神疾病和愛滋病毒感染疾病,也可以使用這項技術來治療或預防。
根據美國國立衛生研究院 (NIH) 的數據,大約有 7,000 種罕見疾病影響著 2500 至 3000 萬美國人。
基因組學擴大用於測試食品品質和安全。基因組編輯技術對於發現新藥物以及識別和治療人類遺傳疾病至關重要。 NGS、DNA 分析和分析以及動植物性因工程都採用基因組編輯。在評估魚類族群時,NGS 可用於 DNA 條碼來識別魚卵和幼蟲,或全面表徵魚類群落。因此,在預測期內,隨著基因組分析應用領域的擴大,對基因組編輯技術的需求可能會增加。
基因編輯療法的研究和開發成本高且耗時。公司和組織可能很難籌集徹底的初步測試和臨床試驗所需的資金。基因編輯藥物的開發很大程度上依賴臨床試驗,而臨床試驗的費用相當昂貴。這些試驗通常涉及多個階段和大量人員,需要證明基因編輯療法的安全性和有效性。因此,高成本是市場拓展的主要障礙。
推動基因編輯市場的主要因素之一是遺傳疾病盛行率的上升。這一趨勢的本質特徵是被診斷出患有罕見疾病和各種遺傳性疾病的人數增加。 CRISPR-Cas9等基因編輯技術能夠識別和糾正導致這些疾病的潛在遺傳異常,因此患者終於可以看到希望。這些因素正在推動市場需求。
基因編輯技術的一個顯著限制是CRISPR技術的脫靶效應。儘管 CRISPR-Cas9 可以以令人難以置信的精確度靶向特定基因,但它也可能導致預期目標以外的位置發生意外修改。由於這種脫靶活性,CRISPR技術的應用可能會帶來風險和困難。這些因素都阻礙了市場的擴張。
這場大流行使基因編輯產業受益,因為社交距離規範和醫院床位短缺迫使家庭患者照護系統充分適應。 COVID-19大流行徹底改變了我們的生活。它也進一步加速了科學界對創造力和協作的承諾。隨著疫情在世界各地蔓延,科學家正忙於開發治療方法、疫苗接種和診斷方法。科學家們正在轉向高通量實驗室自動化、人工智慧和機器學習來應對導致 COVID-19 的新型冠狀病毒 SARS-CoV-2。 SARS-CoV-2 對於隔離感染患者並觀察適當的醫療反應是必要的。因此,基因編輯市場受益於 COVID-19 的爆發。
試劑和消耗品部分估計佔最大佔有率。試劑和消耗品包括各種物品,例如箔片密封件、玻片支架、板、晶片、管條、文庫製備、精製和目標富集套件。由於基因組學在各行業的應用不斷成長,預計消耗品市場將會成長。文庫製備技術的進步也使得 NGS 在磊晶和轉錄組學中的應用成為可能。這些試劑盒用於定序應用,例如標靶定序和全基因組定序。
預計聚集的等距短回文重複片段將在預測期內實現良好的成長。作為傳統基因修飾方法的替代方法,CRISPR 成簇的規則間隔截斷回文重複序列已成為基因編輯的重要工具。 Cas9 酶是 CRISPR 與傳統 DNA 編輯的不同之處。 CRISPR 透過去除受損或不必要的 DNA 序列來重新排列基因,使剩餘的 DNA 呈現新的配置。
在估計期間,北美佔據了最大的市場佔有率。基因編輯最重要的區域市場是北美。美國是該地區的主要收益來源。在美國,創業投資、政府機構和私人公司正在基因編輯領域進行大量資金和投資。這筆資金籌措加速了基因編輯技術的研究、開發和商業化。治療性介入的發展和基因編輯操作的擴展是由於資金籌措的提供而成為可能的。
預計亞太地區在預測期內將出現盈利成長。這是由於技術突破的增加、新興地區生物技術產業的崛起以及癌症和其他遺傳異常盛行率的上升而推動的。 CRISPR技術創新在日本仍在顯著成長。同時,新興的 CRISPR 研究預計將推動印度市場的成長。此外,印度研究人員也開發了廣泛使用的 CRISPR-Cas9 基因編輯方法的不同變異。這種變異可以提高基因編輯的精確度,而不會導致意外的 DNA 變化。因此,這些變數預計將影響未來年度的亞太基因編輯市場。
介紹
促進因素
抑制因素
機會
威脅
產品分析
技術分析
應用分析
最終用戶分析
新興市場
新型冠狀病毒感染疾病(COVID-19)的影響
According to Stratistics MRC, the Global Gene Editing Market is accounted for $7.45 billion in 2023 and is expected to reach $23.05 billion by 2030 growing at a CAGR of 17.5% during the forecast period. A group of technologies known as "gene editing" enables researchers to modify an organism's DNA. These technologies make it possible to change, add, or remove genetic material at particular locations within the genome. Genome editing is a fascinating field for both illness prevention and treatment in humans. More complicated conditions like cancer, heart disease, mental illness, and HIV infection may also be treated and prevented by using it.
According to the National Institutes of Health (NIH), there are approximately 7,000 rare diseases affecting between 25 and 30 million Americans.
Genomics is increasingly being used in food quality and safety testing. Technologies for editing genomes are essential for both finding new drugs and identifying and treating genetic diseases in humans. NGS, DNA analysis and profiling, and genetic engineering of plants and animals all employ genome editing. When evaluating fish populations, NGS can be utilized for DNA barcoding to identify fish eggs and larvae as well as to fully characterize fish communities. Therefore, during the projection period, there will likely be a rise in demand for genome editing technologies due to the expanding application areas of genomics.
Gene editing therapy research and development can be costly and time-consuming. It could be difficult for businesses and organizations to get the financing needed for in-depth pre- and clinical testing. The development of gene editing medicine heavily relies on clinical studies, which are quite expensive. These trials, which usually involve several phases and a large number of people, are required to show the safety and effectiveness of gene editing therapy. Therefore, high costs are a significant barrier to market expansion.
One major factor fueling the gene editing market is the increase in the prevalence of genetic illnesses. An increase in the number of people receiving diagnoses for uncommon diseases and different genetic disorders essentially characterizes this trend. Patients may finally have hope due to gene editing technologies like CRISPR-Cas9, which have the ability to identify and fix the underlying genetic abnormalities causing these illnesses. These factors propel market demand.
A significant constraint of gene editing technology is the off-target impacts of CRISPR technology. Although CRISPR-Cas9 can target certain genes with astonishing precision, it can also cause unintentional alterations at places other than the intended target. The application of CRISPR technology may present risks and difficulties as a result of this off-target activity. These factors hinder market expansion.
The industry for gene editing benefited from the pandemic because social distancing norms and a shortage of hospital beds forced home-based patient care systems to adapt to the fullest. The COVID-19 pandemic has changed our lives. It has also intensified the already swift inclinations toward creation and cooperation among the scientific community. With the pandemic spreading across the globe, scientists are working feverishly to develop treatments, vaccinations, and diagnoses. To tackle SARS-CoV-2, the new coronavirus that causes COVID-19, scientists are looking into high-throughput experimental automation, artificial intelligence, and machine learning. The SARS-CoV-2 is necessary for isolating infected patients and observing appropriate medical responses. Thus, the market for gene editing benefited from the COVID-19 epidemic.
The reagents & consumables segment is estimated to hold the largest share. Reagents and consumables encompass a wide range of items, including foil seals, slide holders, plates, chips, tube strips, library preparation, purification, and target enrichment kits. The market for consumables is predicted to rise as a result of genomics' expanding applicability in a variety of industries. Utilizing NGS in epigenetic and transcriptomics has also been made possible by developments in library preparation technology. Applications for sequencing, including targeted and whole-genome sequencing, employ these kits.
The clustered regularly interspaced short palindromic repeats segment is anticipated to have lucrative growth during the forecast period. As an alternative to conventional genetic alteration methods, CRISPR-Clustered Regularly Interspaced Short Palindromic Repeats have become an essential tool for gene editing. The Cas9 enzymes set CRISPR apart from previous types of DNA editing. By removing damaged or undesirable DNA sequences, CRISPR reorganizes genes so that the remaining DNA can take on new configurations.
North America commanded the largest market share during the extrapolated period. The most significant regional market for gene editing is North America. The US has become this region's main source of revenue. In the US, venture capitalists, governmental organizations, and private companies have made large financial and investment contributions in the gene editing field. Research and development, as well as the commercialization of gene editing technologies, have been accelerated by this financing. The development of therapeutic interventions and the expansion of gene editing businesses have been made possible by the availability of funding.
Asia Pacific is expected to witness profitable growth over the projection period. This is due to increasing technological breakthroughs, a thriving biotechnology industry in emerging regions, and the rising prevalence of cancer and other genetic abnormalities. Innovation in CRISPR technology is still growing significantly in Japan. On the other hand, new CRISPR research is anticipated to propel market growth in India. Additionally, researchers in the nation developed a distinct variation of the widely used CRISPR-Cas9 gene-editing method. The variant may increase the accuracy of gene editing without causing unintended DNA changes. Therefore, in the upcoming years, it is anticipated that these variables will have an effect on the Asia-Pacific gene editing market.
Some of the key players in the Gene Editing Market include: Sangamo Therapeutics, Inc., Beam Therapeutics, Integrated DNA Technologies, Inc., Thermo Fisher Scientific, Horizon Discovery Ltd., Precision Biosciences, CRISPR Therapeutics, GeneScript, Agilent Technologies, Intellia Therapeutics, Inc., Caribou Biosciences, Inc., Lonza, Perkinelmer, Editas, edicine, Tecan Life Sciences, Amsbio and Creative Biogene.
In November 2022, Thermo Fisher Scientific (US) announced the launch of Gibco CTS AAV-MAX Helper-Free AAV Production System, an all-in-one solution suitable for commercial and clinical applications associated with AAV-based gene therapies.
In June 2022, Lonza (Switzerland) and Adva entered into a license agreement that will allow Adva to develop innovative solutions for the cell and gene therapies industry.
In February 2023, Gen Script (China) announced the expansion of its Singapore facility to provide a premium gene synthesis service. This marks a significant expansion of the company's advanced gene-synthesis capability and enables Gen Script to provide the service levels required for novel vaccine and therapeutic development in life sciences.
3.1 Introduction
3.2 Drivers
3.3 Restraints
3.4 Opportunities
3.5 Threats
3.6 Product Analysis
3.7 Technology Analysis
3.8 Application Analysis
3.9 End User Analysis
3.10 Emerging Markets
3.11 Impact of Covid-19