市場調查報告書
商品編碼
1494453
到 2030 年北美微載體市場預測 - 區域分析 - 按產品、設備、應用和最終用戶North America Microcarriers Market Forecast to 2030 - Regional Analysis - by Product, Equipment, Application, and End User |
北美微載體市場預計將從2022年的7.3667億美元成長到2030年的19.3356億美元。
細胞和基因治療製造服務的自動化推動了北美微載體市場
在細胞和基因治療製造中納入自動化將降低污染風險、提高一致性並降低生產成本。 Lonza Cocoon 和 Miltenyi 的 CliniMACS Prodigy 系統是市場上現有的一些設備,這些設備旨在實現單一系統內 CAR-T 流程的大多數順序單元操作的自動化。對細胞和基因療法不斷成長的需求已將全球範圍內的生產從小批量製程轉向大批量製程。細胞和基因療法從學術和臨床環境到大規模生產和商業化的進展進一步推動了商業製造對自動化的需求。 2020 年 7 月,Thermo Fisher Scientific Inc. 和 Lyell Nutrition 合作開發流程,為癌症患者設計有效的細胞療法。根據這項合作關係,兩家公司的目標是提高 T 細胞的能力,並支持開發符合現行良好生產規範 (cGMP) 的綜合平台(系統和軟體)以及試劑、耗材和儀器。此外,美國政府援助的組織正在細胞療法的製造中採用自動化,以提高該國的國家生產能力。因此,自動化正在成為微載體市場的新趨勢。
北美微載體市場概況
北美微載體市場分為美國、加拿大和墨西哥。美國在該地區市場佔據主導地位。北美微載體市場的成長歸因於生物技術和生物製藥公司推出的產品數量不斷增加、主要市場參與者的存在以及各個學術和研究機構的廣泛研發。慢性病盛行率的上升是推動美國微載體市場成長的主要因素。根據美國疾病管制與預防中心 (CDC) 的數據,十分之六的美國人患有至少一種慢性疾病,例如心臟病、中風、癌症或糖尿病。這些疾病是美國死亡和殘疾的重要原因,而且還導致巨大的醫療費用。細胞和基因療法(CGT)領域取得了廣泛的臨床進展,因此這些療法的應用範圍在過去5年中不斷擴大。在 2016 年至 2021 年的分析期間,隨著 12 種新療法的批准和超過 2,900 項臨床試驗的啟動,CGT 創新得到了廣泛的投資。基因編輯技術的進步,以及評估此技術治療效果的臨床試驗,是有利於美國微載體市場的其他因素。例如,Poseida Therapeutics, Inc. 的P-CD19CD20-ALLO1 的研究性新藥(IND) 申請獲得美國食品和藥物管理局(FDA) 批准,這是該公司首款同時靶向CD19 和CD19 的同種異體雙CAR-T 細胞候選產品。 2023 年 4 月,新型同種異體 CAR T 細胞療法在轉移性透明細胞腎細胞癌患者中取得了成果。因此,增加臨床試驗的參與和投資可以加速新療法的採用和可用性。德州大學MD 安德森癌症中心的研究人員領導了I 期試驗,並在美國癌症研究協會(AACR) 2023 年年會上進行了報告。 , Inc. 宣布對支持 Poseida 重新定義癌細胞療法的承諾。安斯泰來投資 5000 萬美元獲得 Poseida 一項臨床階段計畫的許可,該計畫專注於 P-MUC1C-ALLO1,這是一種用於多種實體瘤適應症的同種異體 CAR T 細胞療法。因此,隨著慢性病病例數量的增加以及不同細胞和基因療法的批准,美國對微載體的需求正在增加。
北美微載體市場營收及 2030 年預測(百萬美元)
北美微載體市場細分
北美微載體市場分為產品、設備、應用、最終用戶和國家。
根據產品,北美微載體市場分為微載體珠和培養基和試劑。 2022 年,微載體珠細分市場在北美微載體市場中佔有更大佔有率。
在設備方面,北美微載體市場分為生物反應器、培養皿等。 2022 年,生物反應器領域佔據北美微載體市場的最大佔有率。
根據應用,北美微載體市場分為生物製藥生產、細胞和基因治療、組織工程和再生醫學等。 2022年,生物製藥生產領域在北美微載體市場中佔據最大佔有率。
根據最終用戶,北美微載體市場分為製藥和生物技術公司、合約研究組織和合約製造組織以及學術和研究機構。 2022 年,製藥和生物技術公司領域佔據北美微載體市場的最大佔有率。
根據國家/地區,北美微載體市場分為美國、加拿大和墨西哥。 2022 年,美國主導北美微載體市場。
Teijin Ltd、Bio-Rad Laboratories Inc、Sartorius AG、Danaher Corp、Corning Inc、Eppendorf SE、Asahi Kasei Corp 和 Polysciences Inc 是北美微載體市場上的一些領先公司。
The North America microcarriers market is expected to grow from US$ 736.67 million in 2022 to US$ 1,933.56 million by 2030. It is estimated to record a CAGR of 12.8% from 2022 to 2030.
Automation of Cell and Gene Therapy Manufacturing Services Fuels North America Microcarriers Market
Incorporating automation in cell and gene therapy manufacturing would lead to a reduced risk of contamination, improved consistency, and decreased cost of production. Lonza Cocoon and the CliniMACS Prodigy system from Miltenyi are a few of the devices available in the market that have been designed to enable the automation of most sequential unit operations for a CAR-T process within a single system. The rising demand for cell and gene therapies has shifted production from a small-volume process to a large-volume process worldwide. The progress of cell and gene therapy from an academic and clinical setting to mass production and commercialization further propels the demand for automation in commercial manufacturing. In July 2020, Thermo Fisher Scientific Inc. and Lyell Immunopharma partnered to develop processes to design effective cell therapies for cancer patients. Under this partnership, the companies aim to improve the capability of T-cells and support the development of an integrated current good manufacturing practice (cGMP) compliant platform (system and software), along with reagents, consumables, and instruments. Further, the US government-aided organizations are adopting automation in the manufacturing of cell therapies to increase the national production capabilities of the country. Thus, automation is emerging as a new trend in the microcarriers market.
North America Microcarriers Market Overview
The North America microcarriers market is segmented into the US, Canada, and Mexico. The US dominates the market in this region. The growth of the microcarriers market in North America is attributed to the increasing number of product launches by biotechnology and biopharmaceutical companies, the presence of key market players, and extensive R&D by various academic and research institutes. The rising prevalence of chronic diseases is a leading factor propelling the growth of the microcarrier market in the US. According to the Centers for Disease Control and Prevention (CDC), 6 in 10 Americans live with at least 1 chronic disease, such as heart disease and stroke, cancer, or diabetes. These diseases are the significant causes of mortality and disability in the US, and they also lead to significant costs of healthcare. There have been extensive clinical developments in the field of cell and gene therapies (CGT), owing to which the application range of these therapies has expanded in the past 5 years. With the approval of 12 new therapies and the commencement of over 2,900 clinical trials during the analysis period of 2016-2021, there have been extensive investments in CGT innovations. Technological advancements in gene editing, followed by clinical trials to evaluate the therapeutic effectiveness of the technique, are the other factors that have benefitted the microcarriers market in the US. For example, Poseida Therapeutics, Inc. received the US Food and Drug Administration (FDA) approval for its Investigational New Drug (IND) application for P-CD19CD20-ALLO1-the company's first allogeneic dual CAR-T cell product candidate targeting both CD19 and CD20 antigens for the treatment of relapsed or refractory B-cell malignancies-being developed in partnership with Roche. In April 2023, Novel allogeneic CAR T-cell therapy delivered results in patients with metastatic clear cell renal cell carcinoma. Thus, increased participation and investments in clinical trials can accelerate the adoption and availability of new therapies. Researchers at the University of Texas MD Anderson Cancer Center led the Phase I trial and presented at the American Association for Cancer Research (AACR) Annual Meeting 2023. In August 2023, Astellas Pharma Inc. and Poseida Therapeutics, Inc. announced a strategic investment to support the advancement of Poseida's commitment to redefining cancer cell therapy. Astellas invested US$ 50 million to license one of Poseida's clinical-stage programs focusing on P-MUC1C-ALLO1, an allogeneic CAR T-cell therapy for multiple solid tumor indications. Thus, the demand for microcarriers is on the rise in the US with the increasing number of chronic disease cases and approval of different cell and gene therapies.
North America Microcarriers Market Revenue and Forecast to 2030 (US$ Million)
North America Microcarriers Market Segmentation
The North America microcarriers market is segmented into product, equipment, application, end user, and country.
Based on product, the North America microcarriers market is bifurcated into microcarriers beads and media & reagents. The microcarriers beads segment held a larger share of the North America microcarriers market in 2022.
In terms of equipment, the North America microcarriers market is segmented into bioreactors, culture vessels, and others. The bioreactors segment held the largest share of the North America microcarriers market in 2022.
Based on application, the North America microcarriers market is segmented into biopharmaceutical production, cell and gene therapy, tissue engineering and regenerative medicine, and other. The biopharmaceutical production segment held the largest share of the North America microcarriers market in 2022. Further, biopharmaceutical production segment is categorized into therapeutic protein production and vaccine production.
Based on end user, the North America microcarriers market is segmented into pharmaceutical & biotechnology companies, contract research organizations & contract manufacturing organizations, and academic & research institutes. The pharmaceutical & biotechnology companies segment held the largest share of the North America microcarriers market in 2022.
Based on country, the North America microcarriers market is segmented into the US, Canada, and Mexico. The US dominated the North America microcarriers market in 2022.
Teijin Ltd, Bio-Rad Laboratories Inc, Sartorius AG, Danaher Corp, Corning Inc, Eppendorf SE, Asahi Kasei Corp, and Polysciences Inc are some of the leading companies operating in the North America microcarriers market.