全球高通量篩選市場規模（依技術、應用、產品/服務、地區、範圍和預測）

高通量篩選市場規模及預測

高通量篩選市場規模預計在 2024 年達到 232.6 億美元，到 2031 年將達到 400.4 億美元，2024 年至 2031 年的複合年增長率為 7.75%。

高通量篩選 (HTS) 是藥物發現和其他研究領域中使用的一種方法，用於針對特定目標或條件快速測試數千種化合物、生物樣本或遺傳物質。

此方法利用自動化技術同時進行多項檢測，有效辨識潛在的候選藥物和生物活性。 HTS 通常使用機器人、專用軟體和複雜的檢測系統來快速處理和分析樣本。

在應用中，HTS 主要用於藥物研究，透過篩選大量化合物的功效、毒性或與特定生物標靶的相互作用來識別有前景的候選藥物。

它們也用於基因組學和蛋白​​質組學，以研究基因功能、蛋白質相互作用和疾病機制。此外，HTS 還用於環境和農業科學，以評估化學物質對不同生物系統的影響並發現新的農業化合物。

高通量篩選的全球市場動態

主要市場驅動因子

藥物研發需求不斷增長：對新型有效藥物的需求不斷增長，推動了高通量篩選 (HTS) 的採用，以便從龐大的化合物庫中高效識別潛在的候選藥物。根據美國食品藥物管理局（FDA）的數據，截至 2023 年，開發一種新藥的平均成本估計為 26 億美元，從最初發現到上市批准需要 10 至 15 年的時間。高成本和長時間推動了對 HTS 等更有效的篩選方法的需求。

自動化技術的進步：機器人和自動化技術的不斷改進正在提高 HTS 流程的效率和速度，使其更適用於大規模研究並更有效。美國國家標準與技術研究所 (NIST) 在 2023 年報告稱，實驗室自動化的進步使過去五年來 HTS 系統的平均吞吐量提高了 35%。

越來越關注個人化醫療：個人化醫療的轉變需要高通量方法來分析複雜的生物數據並確定針對個別患者的治療目標。個人化醫療聯盟報告稱，2023 年 FDA 批准的新藥中 25% 將被歸類為個人化醫療，高於 2022 年的 20%。

增加對研發的投入：增加對生物醫學研究和藥品研發的資金和投資將支持 HTS 能力的擴展，實現更全面和多樣化的篩選。美國藥品研究與製造商協會 (PhRMA) 報告稱，其會員公司將在 2023 年花費約 1,023 億美元用於研發，比 2022 年增長 7.5%。

擴大生物技術和基因組學：擴大生物技術和基因組學研究需要先進的篩選技術來處理大型數據集並確定治療發展的關鍵遺傳和分子目標。例如，2024 年 3 月，Ginkgo Bioworks 宣佈推出一個整合基因組數據分析的新型 HTS 平台，使其能夠每天篩檢超過 10 萬個基因突變，以用於潛在的治療應用。

主要問題

複雜的資料管理：HTS 產生大量數據，這些資料難以管理、分析和有效解釋。處理這些數據需要複雜的軟體和熟練的人員，並且需要大量的資源。

技術限制與可靠性問題：HTS 技術可能面臨檢測可靠性、靈敏度和特異性的問題。技術限制可能導致假陽性和假陰性，進而影響篩檢過程的準確性和效率。

整合課題：將 HTS 系統整合到現有的實驗室工作流程和資料基礎架構中可能非常複雜且耗時。相容性問題和大量驗證的需要可能會阻礙無縫實施。

監管和合規障礙：嚴格的監管要求和遵守行業標準的需要使 HTS 流程變得複雜。確保遵守這些法規會增加營運課題和成本。

前期成本高：購買和維護先進的 HTS 設備所需的大量資金，以及開發和驗證篩選檢測的相關成本，對於小型實驗室和組織來說可能是難以承受的。

主要趨勢

整合人工智慧和機器學習：將人工智慧和機器學習融入 HTS 將增強數據分析和解釋。這些技術提高了篩選結果的準確性，更有效地識別模式和潛在匹配，並減少了資料處理所需的時間。根據美國國立衛生研究院 (NIH) 2023 年的報告，從 2020 年到 2023 年，人工智慧和機器學習在藥物發現和 HTS 中的使用增加了 35%。這種整合將藥物發現篩選活動中首次發現的時間縮短了 40%。

檢測技術的進步：檢測技術的創新，例如開發更靈敏、更具體的檢測方法，正在擴展 HTS 的功能。檢測方法的開發使得對生物標靶的篩選更加詳細和可靠，有助於更有效地發現和開發藥物。 2023 年 12 月，Promega 公司推出了一種增強型生物發光報告基因檢測方法，可為蛋白質-蛋白質交互作用研究提供 10 倍更高的靈敏度。

自動化和機器人技術的採用日益廣泛：HTS 系統中自動化和機器人技術的提高正在推動吞吐量和效率的提高。自動化平台簡化了篩選流程、減少了人為錯誤並擴大了樣本量，促進更快、更具成本效益的研究和發現。 HighRes Biosolutions 與一家大型製藥公司合作開發一種用於自適應篩選的人工智慧驅動的機器人系統，並於 2024 年 1 月宣佈了這一消息。

目錄

第 1 章簡介

• 市場定義
• 市場區隔
• 研究方法

第 2 章執行摘要

• 主要發現 市場概況 市集亮點

第三章 市場概覽

• 市場規模與成長潛力
• 市場趨勢
• 市場推動因素
• 市場限制
• 市場機會
• 波特五力分析

第 4 章。

• 基於細胞的檢測 晶片實驗室（LOC）
• 無標籤技術
• 超高通量篩選 (UHTS)

第五章高通量篩選市場（按應用）

• 藥物研發
• 目標識別
• 首次放映
• 毒理學

6. 高通量篩選市場（依產品與服務）

• 設備
• 消耗品
• 服務
• 軟體

第 7 章 區域分析

• 北美洲
• 美國
• 加拿大
• 墨西哥
• 歐洲
• 英國
• 德國
• 法國
• 義大利 亞太地區
• 中國
• 日本
• 印度
• 澳大利亞
• 拉丁美洲
• 巴西
• 阿根廷
• 智利
• 中東和非洲
• 南非
• 沙烏地阿拉伯
• 阿拉伯聯合大公國

第 8 章 市場動態

• 市場推動因素
• 市場限制
• 市場機會
• COVID-19 對市場的影響

第 9 章 競爭格局

• 大型公司
• 市佔率分析

第十章 公司簡介

• Rheon Automatic Machinery
• GEA Group
• Middleby Corporation
• Marel
• Bettcher Industries
• Gunther Maschinenbau GmbH
• Formax, Inc.
• Magurit Gefrierschneider GmbH
• Minerva Omega Group
• Metalbud NOWICKI

第 11 章 市場展望與機會

• 新興技術
• 未來市場趨勢
• 投資機會

第 12 章附錄

• 縮寫列表
• 來源與參考文獻

High Throughput Screening Market Size And Forecast

High Throughput Screening Market size was valued at USD 23.26 Billion in 2024 and is projected to reach USD 40.04 Billion by 2031, growing at a CAGR of 7.75% from 2024 to 2031.

High Throughput Screening (HTS) is a method used in drug discovery and other research fields to rapidly test thousands of compounds, biological samples, or genetic materials against specific targets or conditions.

This technique utilizes automated technologies to conduct a large number of assays simultaneously, enabling the efficient identification of potential drug candidates or biological activities. HTS typically involves robotics, specialized software, and sophisticated detection systems to process and analyze samples quickly.

In terms of application, HTS is predominantly used in pharmaceutical research to identify promising drug candidates by screening large libraries of compounds for their efficacy, toxicity, or interactions with specific biological targets.

It is also employed in genomics and proteomics to study gene function, protein interactions, and disease mechanisms. Additionally, HTS is utilized in environmental and agricultural sciences to assess the impact of chemicals on various biological systems and to discover new agricultural compounds.

Global High Throughput Screening Market Dynamics

The key market dynamics that are shaping the global high throughput screening market include:

Key Market Drivers

Rising Drug Discovery Demands: The increasing need for new and effective pharmaceuticals drives the adoption of High Throughput Screening (HTS) to efficiently identify potential drug candidates from vast compound libraries. According to the U.S. Food and Drug Administration (FDA), as of 2023, the average cost to develop a new drug was estimated at USD 2.6 Billion, with a timeline of 10-15 years from initial discovery to market approval. This high cost and long timeline drive the need for more efficient screening methods like HTS.

Advancements in Automation Technologies: Continuous improvements in robotics and automation technologies enhance the efficiency and speed of HTS processes, making them more accessible and effective for large-scale research. The National Institute of Standards and Technology (NIST) reported in 2023 that advancements in laboratory automation have increased the average throughput of HTS systems by 35% over the past five years.

Growing Focus on Personalized Medicine: The shift towards personalized medicine necessitates high-throughput methods to analyze complex biological data and identify tailored therapeutic targets for individual patients. The Personalized Medicine Coalition reported that 25% of all new drugs approved by the FDA in 2023 were classified as personalized medicines, up from 20% in 2022.

Increased Investment in Research and Development: Growing funding and investment in biomedical research and pharmaceutical R&D support the expansion of HTS capabilities, enabling more comprehensive and diverse screening efforts. The Pharmaceutical Research and Manufacturers of America (PhRMA) reported that its member companies invested an estimated $102.3 billion in R&D in 2023, up 7.5% from 2022.

Expansion of Biotechnology and Genomics: The rise in biotechnology and genomics research requires advanced screening technologies to handle large datasets and identify key genetic and molecular targets for therapeutic development. For instance, in March 2024, Ginkgo Bioworks unveiled a new HTS platform integrating genomic data analysis, capable of screening over 100,000 genetic variants per day for potential therapeutic applications.

Key Challenges:

Complex Data Management: HTS generates vast amounts of data that can be challenging to manage, analyze, and interpret effectively. Handling this data requires sophisticated software and skilled personnel, which can be resource-intensive.

Technical Limitations and Reliability Issues: HTS technologies may face issues with assay reliability, sensitivity, and specificity. Technical limitations can lead to false positives or negatives, impacting the accuracy and efficiency of the screening process.

Integration Challenges: Integrating HTS systems with existing laboratory workflows and data infrastructure can be complex and time-consuming. Compatibility issues and the need for extensive validation can hinder seamless implementation.

Regulatory and Compliance Hurdles: The need to adhere to stringent regulatory requirements and industry standards can complicate the HTS process. Ensuring compliance with these regulations adds to the operational challenges and costs.

High Initial Costs: The significant capital required for purchasing and maintaining advanced HTS equipment, along with the costs associated with developing and validating screening assays, can be prohibitive for smaller laboratories and organizations.

Key Trends

Integration of Artificial Intelligence and Machine Learning: The incorporation of AI and machine learning into HTS is enhancing data analysis and interpretation. These technologies improve the accuracy of screening results, identify patterns and potential hits more efficiently, and reduce the time required for data processing. According to a report by the National Institutes of Health (NIH) in 2023, the use of AI and machine learning in drug discovery and HTS increased by 35% from 2020 to 2023. This integration has led to a 40% reduction in the time required for initial hit identification in drug screening campaigns.

Advancements in Assay Technologies: Innovations in assay technologies, such as the development of more sensitive and specific assays, are expanding the capabilities of HTS. Enhanced assay methods allow for more detailed and reliable screening of biological targets, contributing to more effective drug discovery and development. Promega Corporation launched an enhanced bioluminescent reporter assay in December 2023, offering 10 times higher sensitivity for protein-protein interaction studies.

Growing Adoption of Automation and Robotics: Increased automation and robotics in HTS systems are driving higher throughput and efficiency. Automated platforms streamline the screening process, reduce human error, and enable the handling of larger sample volumes, facilitating faster and more cost-effective research and discovery. HighRes Biosolutions partnered with a leading pharmaceutical company to develop an AI-driven robotic system for adaptive screening, announced in January 2024.

Global High Throughput Screening Market Regional Analysis

Here is a more detailed regional analysis of the global high throughput screening market:

North America

North America dominating the global high throughput screening (HTS) market, driven by its advanced research infrastructure and strong focus on innovation in pharmaceuticals and biotechnology. The United States and Canada are at the forefront of adopting and integrating HTS technologies, leveraging their well-established R&D ecosystem and significant investments in cutting-edge research.

Several key factors contribute to North America's dominance in the HTS market. The region's robust pharmaceutical and biotechnology industries drive demand for efficient drug discovery and development processes, supported by substantial funding and a strong pipeline of research projects. Additionally, North America's well-developed infrastructure, including leading research institutions and pharmaceutical companies, further fuels the growth of HTS technologies.

In North America, notable trends include the increasing integration of artificial intelligence and machine learning into HTS processes to enhance data analysis and predictive capabilities. There is also a growing emphasis on personalized medicine, leading to more sophisticated and tailored screening assays. Furthermore, advancements in automation and robotics are streamlining HTS workflows, boosting efficiency, and enabling higher throughput in drug discovery and development.

Asia Pacific

Asia-Pacific, with China as a key player, is witnessing rapid growth in the High Throughput Screening (HTS) market. The region's expanding biotechnology and pharmaceutical sectors are driving the adoption of advanced HTS technologies, positioning Asia-Pacific as a significant and fast-growing market for screening solutions.

The rapid growth of the HTS market in Asia-Pacific is driven by several factors. In China, substantial investments in pharmaceutical research and biotechnology are fueling demand for efficient drug discovery tools. Additionally, the region's expanding research infrastructure, increasing focus on personalized medicine, and supportive government policies contribute to the accelerated adoption of HTS technologies.

Key trends in the Asia-Pacific HTS market include the rising integration of advanced automation and robotics to enhance screening efficiency and throughput. There is also a growing emphasis on developing and utilizing novel screening assays to support complex drug discovery processes. Furthermore, increasing collaborations between regional research institutions and global pharmaceutical companies are driving innovation and expanding the reach of HTS technologies across the region.

Global High Throughput Screening Market: Segmentation Analysis

The Global High Throughput Screening Market is Segmented on the basis of Technology, Application, Product & Service, And Geography.

High Throughput Screening Market, By Technology

• Cell-Based Assays
• Lab-on-a-Chip (LOC)
• Label-Free Technology
• Ultra-High-Throughput Screening (UHTS)

Based on Technology, the Global High Throughput Screening Market is bifurcated into Cell-Based Assays, Lab-on-a-Chip (LOC), Label-Free Technology, Ultra-High-Throughput Screening (UHTS). The cell-based assay technology is projected to lead the market during the forecast. This dominance is primarily due to the ability of this technology to generate multiple biologically relevant data. Also, the assessing compound attributes is another factor projected to enhance the application of cell-based assay.

High Throughput Screening Market, By Application

• Drug Discovery
• Target Identification
• Primary Screening
• Toxicology

Based on Application, the Global High Throughput Screening Market is bifurcated into Drug Discovery, Target Identification, Primary Screening, and Toxicology. In the high throughput screening (HTS) market, cell-based assays are currently dominating due to their broad applicability in drug discovery and biological research. These assays are essential for evaluating cellular responses to various compounds and are widely used across pharmaceutical and biotechnology industries. Conversely, Label-Free Technology is the rapidly growing segment, driven by its ability to provide real-time, non-invasive measurements without the need for labels or dyes. This technology offers advantages such as reduced assay complexity and improved accuracy, contributing to its increasing adoption and rapid growth in the HTS market.

High Throughput Screening Market, By Product & Service

• Instruments
• Consumables
• Services
• Software

Based on Product & Service, the Global High Throughput Screening Market is bifurcated into Instruments, Consumables, Services, and Software. In the high throughput screening (HTS) market, instruments are the dominating segment, as they form the backbone of HTS systems, enabling the automation and high-throughput capabilities necessary for large-scale screening processes. The demand for sophisticated and high-performance HTS instruments drives this segment's leading position. Meanwhile, software is the rapidly growing segment, fueled by advancements in data analytics, machine learning, and artificial intelligence. Enhanced software solutions for data management and analysis are becoming increasingly vital for interpreting complex screening results and improving overall HTS efficiency, contributing to its swift growth.

High Throughput Screening Market, By Geography

• North America
• Europe
• Asia Pacific
• Rest of the World

Based on Geography, the Global High Throughput Screening Market is classified into North America, Europe, Asia Pacific, and the Rest of the world. In the high throughput screening (HTS) market, North America is the dominating region, driven by its advanced research infrastructure, strong pharmaceutical and biotechnology sectors, and significant investments in cutting-edge HTS technologies. The region's established market presence and extensive R&D activities contribute to its leading position. Conversely, Asia Pacific is the rapidly growing region, with China and other countries in the area experiencing substantial growth due to increasing investments in research and development, expanding pharmaceutical industries, and the adoption of advanced HTS technologies. This region's rapid industrialization and focus on innovation are fueling its swift expansion in the HTS market.

Key Players

The "Global High Throughput Screening Market" study report will provide valuable insight with an emphasis on the global market. The major players in the market are Rheon Automatic Machinery, GEA Group, Middleby Corporation, Marel, Bettcher Industries, Formax, Inc., Magurit Gefrierschneider GmbH, Minerva Omega Group, Metalbud NOWICKI.

Our market analysis also entails a section solely dedicated to such major players wherein our analysts provide an insight into the financial statements of all the major players, along with its product benchmarking and SWOT analysis. The competitive landscape section also includes key development strategies, market share, and market ranking analysis of the above-mentioned players globally.

• Global High Throughput Screening Market Recent Developments
• In October 2023, Thermo Fisher Scientific launched the new Orbitrap Exploris 120 Mass Spectrometer, designed to enhance high-throughput screening capabilities with superior sensitivity and accuracy for drug discovery applications.
• In November 2023, PerkinElmer introduced its upgraded Chemagic 360 automated sample preparation system, which integrates advanced robotics for streamlined high-throughput screening workflows in genomics and proteomics research.
• In December 2023, Agilent Technologies released a next-generation open-access high-throughput screening platform, featuring enhanced data analytics tools and a more flexible assay environment to accelerate drug development.

TABLE OF CONTENTS

1. Introduction

• Market Definition
• Market Segmentation
• Research Methodology

2. Executive Summary

• Key Findings
• Market Overview
• Market Highlights

3. Market Overview

• Market Size and Growth Potential
• Market Trends
• Market Drivers
• Market Restraints
• Market Opportunities
• Porter's Five Forces Analysis

4. High Throughput Screening Market, By Technology

• Cell-based Assays
• Lab-on-a-Chip (LOC)
• Label-free Technology
• Ultra-high-throughput Screening (UHTS)

5. High Throughput Screening Market, By Application

• Drug Discovery
• Target Identification
• Primary Screening
• Toxicology

6. High Throughput Screening Market, By Product & Service

• Instruments
• Consumables
• Services
• Software

7. Regional Analysis

• North America
• United States
• Canada
• Mexico
• Europe
• United Kingdom
• Germany
• France
• Italy
• Asia-Pacific
• China
• Japan
• India
• Australia
• Latin America
• Brazil
• Argentina
• Chile
• Middle East and Africa
• South Africa
• Saudi Arabia
• UAE

8. Market Dynamics

• Market Drivers
• Market Restraints
• Market Opportunities
• Impact of COVID-19 on the Market

9. Competitive Landscape

• Key Players
• Market Share Analysis

10. Company Profiles

• Rheon Automatic Machinery
• GEA Group
• Middleby Corporation
• Marel
• Bettcher Industries
• Gunther Maschinenbau GmbH
• Formax, Inc.
• Magurit Gefrierschneider GmbH
• Minerva Omega Group
• Metalbud NOWICKI

11. Market Outlook and Opportunities

• Emerging Technologies
• Future Market Trends
• Investment Opportunities

12. Appendix

• List of Abbreviations
• Sources and References